|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US3896111A
(en)
|
1973-02-20 |
1975-07-22 |
Research Corp |
Ansa macrolides
|
|
US4151042A
(en)
|
1977-03-31 |
1979-04-24 |
Takeda Chemical Industries, Ltd. |
Method for producing maytansinol and its derivatives
|
|
US4137230A
(en)
|
1977-11-14 |
1979-01-30 |
Takeda Chemical Industries, Ltd. |
Method for the production of maytansinoids
|
|
USRE30985E
(en)
|
1978-01-01 |
1982-06-29 |
|
Serum-free cell culture media
|
|
US4265814A
(en)
|
1978-03-24 |
1981-05-05 |
Takeda Chemical Industries |
Matansinol 3-n-hexadecanoate
|
|
US4307016A
(en)
|
1978-03-24 |
1981-12-22 |
Takeda Chemical Industries, Ltd. |
Demethyl maytansinoids
|
|
JPS5562090A
(en)
|
1978-10-27 |
1980-05-10 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS55164687A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS5566585A
(en)
|
1978-11-14 |
1980-05-20 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
US4256746A
(en)
|
1978-11-14 |
1981-03-17 |
Takeda Chemical Industries |
Dechloromaytansinoids, their pharmaceutical compositions and method of use
|
|
JPS55102583A
(en)
|
1979-01-31 |
1980-08-05 |
Takeda Chem Ind Ltd |
20-acyloxy-20-demethylmaytansinoid compound
|
|
JPS55162791A
(en)
|
1979-06-05 |
1980-12-18 |
Takeda Chem Ind Ltd |
Antibiotic c-15003pnd and its preparation
|
|
JPS55164685A
(en)
|
1979-06-08 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
JPS55164686A
(en)
|
1979-06-11 |
1980-12-22 |
Takeda Chem Ind Ltd |
Novel maytansinoid compound and its preparation
|
|
US4309428A
(en)
|
1979-07-30 |
1982-01-05 |
Takeda Chemical Industries, Ltd. |
Maytansinoids
|
|
JPS5645483A
(en)
|
1979-09-19 |
1981-04-25 |
Takeda Chem Ind Ltd |
C-15003phm and its preparation
|
|
JPS5645485A
(en)
|
1979-09-21 |
1981-04-25 |
Takeda Chem Ind Ltd |
Production of c-15003pnd
|
|
EP0028683A1
(en)
|
1979-09-21 |
1981-05-20 |
Takeda Chemical Industries, Ltd. |
Antibiotic C-15003 PHO and production thereof
|
|
US4270537A
(en)
|
1979-11-19 |
1981-06-02 |
Romaine Richard A |
Automatic hypodermic syringe
|
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
WO1982001188A1
(en)
|
1980-10-08 |
1982-04-15 |
Takeda Chemical Industries Ltd |
4,5-deoxymaytansinoide compounds and process for preparing same
|
|
US4450254A
(en)
|
1980-11-03 |
1984-05-22 |
Standard Oil Company |
Impact improvement of high nitrile resins
|
|
US4419446A
(en)
|
1980-12-31 |
1983-12-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant DNA process utilizing a papilloma virus DNA as a vector
|
|
US4315929A
(en)
|
1981-01-27 |
1982-02-16 |
The United States Of America As Represented By The Secretary Of Agriculture |
Method of controlling the European corn borer with trewiasine
|
|
US4313946A
(en)
|
1981-01-27 |
1982-02-02 |
The United States Of America As Represented By The Secretary Of Agriculture |
Chemotherapeutically active maytansinoids from Trewia nudiflora
|
|
JPS57192389A
(en)
|
1981-05-20 |
1982-11-26 |
Takeda Chem Ind Ltd |
Novel maytansinoid
|
|
US4596792A
(en)
|
1981-09-04 |
1986-06-24 |
The Regents Of The University Of California |
Safe vaccine for hepatitis containing polymerized serum albumin
|
|
US4741900A
(en)
|
1982-11-16 |
1988-05-03 |
Cytogen Corporation |
Antibody-metal ion complexes
|
|
US4601978A
(en)
|
1982-11-24 |
1986-07-22 |
The Regents Of The University Of California |
Mammalian metallothionein promoter system
|
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
|
US4599231A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
|
US4599230A
(en)
|
1984-03-09 |
1986-07-08 |
Scripps Clinic And Research Foundation |
Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
|
|
US4965199A
(en)
|
1984-04-20 |
1990-10-23 |
Genentech, Inc. |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
|
|
US4970198A
(en)
|
1985-10-17 |
1990-11-13 |
American Cyanamid Company |
Antitumor antibiotics (LL-E33288 complex)
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
US4601903A
(en)
|
1985-05-01 |
1986-07-22 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease
|
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
|
US5567610A
(en)
|
1986-09-04 |
1996-10-22 |
Bioinvent International Ab |
Method of producing human monoclonal antibodies and kit therefor
|
|
US5811128A
(en)
|
1986-10-24 |
1998-09-22 |
Southern Research Institute |
Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
|
|
US5075109A
(en)
|
1986-10-24 |
1991-12-24 |
Southern Research Institute |
Method of potentiating an immune response
|
|
US4886499A
(en)
|
1986-12-18 |
1989-12-12 |
Hoffmann-La Roche Inc. |
Portable injection appliance
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
US5079233A
(en)
|
1987-01-30 |
1992-01-07 |
American Cyanamid Company |
N-acyl derivatives of the LL-E33288 antitumor antibiotics, composition and methods for using the same
|
|
GB8704027D0
(en)
|
1987-02-20 |
1987-03-25 |
Owen Mumford Ltd |
Syringe needle combination
|
|
AU600575B2
(en)
|
1987-03-18 |
1990-08-16 |
Sb2, Inc. |
Altered antibodies
|
|
US4849222A
(en)
|
1987-03-24 |
1989-07-18 |
The Procter & Gamble Company |
Mixtures for treating hypercholesterolemia
|
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
|
US4940460A
(en)
|
1987-06-19 |
1990-07-10 |
Bioject, Inc. |
Patient-fillable and non-invasive hypodermic injection device assembly
|
|
US4975278A
(en)
|
1988-02-26 |
1990-12-04 |
Bristol-Myers Company |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
|
|
US5004697A
(en)
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
|
US5053394A
(en)
|
1988-09-21 |
1991-10-01 |
American Cyanamid Company |
Targeted forms of methyltrithio antitumor agents
|
|
JP2670680B2
(ja)
|
1988-02-24 |
1997-10-29 |
株式会社ビーエムジー |
生理活性物質含有ポリ乳酸系微小球およびその製造法
|
|
US5339163A
(en)
|
1988-03-16 |
1994-08-16 |
Canon Kabushiki Kaisha |
Automatic exposure control device using plural image plane detection areas
|
|
JPH01287029A
(ja)
|
1988-05-13 |
1989-11-17 |
Mect Corp |
新規抗ウィルス剤
|
|
DE68925971T2
(de)
|
1988-09-23 |
1996-09-05 |
Cetus Oncology Corp |
Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
FR2638359A1
(fr)
|
1988-11-03 |
1990-05-04 |
Tino Dalto |
Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
|
|
US5175384A
(en)
|
1988-12-05 |
1992-12-29 |
Genpharm International |
Transgenic mice depleted in mature t-cells and methods for making transgenic mice
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
ES2096590T3
(es)
|
1989-06-29 |
1997-03-16 |
Medarex Inc |
Reactivos biespecificos para la terapia del sida.
|
|
US5690938A
(en)
|
1989-07-07 |
1997-11-25 |
Oravax, Inc. |
Oral immunization with multiple particulate antigen delivery system
|
|
US5518725A
(en)
|
1989-09-25 |
1996-05-21 |
University Of Utah Research Foundation |
Vaccine compositions and method for induction of mucosal immune response via systemic vaccination
|
|
CA2026147C
(en)
|
1989-10-25 |
2006-02-07 |
Ravi J. Chari |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5238843A
(en)
|
1989-10-27 |
1993-08-24 |
Genencor International, Inc. |
Method for cleaning a surface on which is bound a glycoside-containing substance
|
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
|
WO1991010741A1
(en)
|
1990-01-12 |
1991-07-25 |
Cell Genesys, Inc. |
Generation of xenogeneic antibodies
|
|
US5061620A
(en)
|
1990-03-30 |
1991-10-29 |
Systemix, Inc. |
Human hematopoietic stem cell
|
|
US5268164A
(en)
|
1990-04-23 |
1993-12-07 |
Alkermes, Inc. |
Increasing blood-brain barrier permeability with permeabilizer peptides
|
|
US5112596A
(en)
|
1990-04-23 |
1992-05-12 |
Alkermes, Inc. |
Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
|
|
AP249A
(en)
|
1990-04-24 |
1993-03-17 |
Biota Scient Management Pty Ltd |
Anti-viral compounds.
|
|
WO1991016073A1
(en)
|
1990-04-24 |
1991-10-31 |
The University Of Newcastle Research Associates Limited |
Oral vaccine comprising antigen surface-associated with red blood cells
|
|
US5229275A
(en)
|
1990-04-26 |
1993-07-20 |
Akzo N.V. |
In-vitro method for producing antigen-specific human monoclonal antibodies
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
DE69132709T2
(de)
|
1990-06-29 |
2002-06-20 |
Large Scale Biology Corp., Vacaville |
Melaninproduktion durch transformierte mikroorganismen
|
|
US5190521A
(en)
|
1990-08-22 |
1993-03-02 |
Tecnol Medical Products, Inc. |
Apparatus and method for raising a skin wheal and anesthetizing skin
|
|
ATE158021T1
(de)
|
1990-08-29 |
1997-09-15 |
Genpharm Int |
Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5714374A
(en)
|
1990-09-12 |
1998-02-03 |
Rutgers University |
Chimeric rhinoviruses
|
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
|
WO1992006691A1
(en)
|
1990-10-19 |
1992-04-30 |
Biota Scientific Management Pty. Ltd. |
Anti-viral compounds that bind the active site of influenza neuramidase and display in vivo activity against orthomyxovirus and paramyxovirus
|
|
US5264365A
(en)
|
1990-11-09 |
1993-11-23 |
Board Of Regents, The University Of Texas System |
Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides
|
|
US5508192A
(en)
|
1990-11-09 |
1996-04-16 |
Board Of Regents, The University Of Texas System |
Bacterial host strains for producing proteolytically sensitive polypeptides
|
|
DK0564531T3
(da)
|
1990-12-03 |
1998-09-28 |
Genentech Inc |
Berigelsesfremgangsmåde for variantproteiner med ændrede bindingsegenskaber
|
|
US5527288A
(en)
|
1990-12-13 |
1996-06-18 |
Elan Medical Technologies Limited |
Intradermal drug delivery device and method for intradermal delivery of drugs
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
ATE158415T1
(de)
|
1991-04-30 |
1997-10-15 |
Eukarion Inc |
Kationisierte antikörper gegen intrazelluläre eiweisse
|
|
CA2103059C
(en)
|
1991-06-14 |
2005-03-22 |
Paul J. Carter |
Method for making humanized antibodies
|
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
|
GB9118204D0
(en)
|
1991-08-23 |
1991-10-09 |
Weston Terence E |
Needle-less injector
|
|
SE9102652D0
(sv)
|
1991-09-13 |
1991-09-13 |
Kabi Pharmacia Ab |
Injection needle arrangement
|
|
WO1993006217A1
(en)
|
1991-09-19 |
1993-04-01 |
Genentech, Inc. |
EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES
|
|
JP3540315B2
(ja)
|
1991-09-23 |
2004-07-07 |
メディカル リサーチ カウンシル |
キメラ抗体の製造−組合せアプローチ
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
|
FI941572L
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenetelmä
|
|
US5288502A
(en)
|
1991-10-16 |
1994-02-22 |
The University Of Texas System |
Preparation and uses of multi-phase microspheres
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
ES2137981T3
(es)
|
1991-11-19 |
2000-01-01 |
Univ Virginia |
Tratamiento combinado por agentes antimediaticos y antiviricos de resfriados comunes.
|
|
JPH0826057B2
(ja)
|
1992-01-16 |
1996-03-13 |
株式会社ディ・ディ・エス研究所 |
シアル酸オリゴ糖誘導体及び微粒子キャリヤー
|
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
|
EP1514934B1
(en)
|
1992-02-06 |
2008-12-31 |
Novartis Vaccines and Diagnostics, Inc. |
Biosynthetic binding protein for cancer marker
|
|
US5328483A
(en)
|
1992-02-27 |
1994-07-12 |
Jacoby Richard M |
Intradermal injection device with medication and needle guard
|
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
US5326856A
(en)
|
1992-04-09 |
1994-07-05 |
Cytogen Corporation |
Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
|
|
ZA932522B
(en)
|
1992-04-10 |
1993-12-20 |
Res Dev Foundation |
Immunotoxins directed against c-erbB-2(HER/neu) related surface antigens
|
|
JP2904647B2
(ja)
|
1992-06-12 |
1999-06-14 |
株式会社蛋白工学研究所 |
5−ブロム−4−クロロインド−3−イル−2−シアル酸の製造方法
|
|
EP0651805B1
(en)
|
1992-07-17 |
2006-12-13 |
Dana Farber Cancer Institute |
Method of intracellular binding of target molecules
|
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
WO1994002178A1
(en)
|
1992-07-27 |
1994-02-03 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Targeting of liposomes to the blood-brain barrier
|
|
DE69308573T2
(de)
|
1992-08-17 |
1997-08-07 |
Genentech Inc |
Bispezifische immunoadhesine
|
|
US5569189A
(en)
|
1992-09-28 |
1996-10-29 |
Equidyne Systems, Inc. |
hypodermic jet injector
|
|
AU683026B2
(en)
|
1992-10-22 |
1997-10-30 |
Kirin Pharma Kabushiki Kaisha |
Novel shingoglycolipid and use thereof
|
|
US5807722A
(en)
|
1992-10-30 |
1998-09-15 |
Bioengineering Resources, Inc. |
Biological production of acetic acid from waste gases with Clostridium ljungdahlii
|
|
US5334144A
(en)
|
1992-10-30 |
1994-08-02 |
Becton, Dickinson And Company |
Single use disposable needleless injector
|
|
US5736137A
(en)
|
1992-11-13 |
1998-04-07 |
Idec Pharmaceuticals Corporation |
Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma
|
|
RU2139731C1
(ru)
|
1992-11-13 |
1999-10-20 |
Айдек Фармасьютикалс Корпорейшн (US |
Способ лечения, антитела, гибридома
|
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
|
JP3523285B2
(ja)
*
|
1993-01-22 |
2004-04-26 |
雪印乳業株式会社 |
糖分解酵素の製造法
|
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
|
US5374541A
(en)
|
1993-05-04 |
1994-12-20 |
The Scripps Research Institute |
Combined use of β-galactosidase and sialyltransferase coupled with in situ regeneration of CMP-sialic acid for one pot synthesis of oligosaccharides
|
|
US20020037517A1
(en)
|
1993-05-28 |
2002-03-28 |
Hutchens T. William |
Methods for sequencing biopolymers
|
|
WO1994029351A2
(en)
|
1993-06-16 |
1994-12-22 |
Celltech Limited |
Antibodies
|
|
ATE224184T1
(de)
|
1993-10-22 |
2002-10-15 |
Genentech Inc |
Verfahren zur mikroverkapselung von antigenen und verwendung der zusammensetzungen als impfstoffe
|
|
US5369017A
(en)
|
1994-02-04 |
1994-11-29 |
The Scripps Research Institute |
Process for solid phase glycopeptide synthesis
|
|
DE69506383T2
(de)
|
1994-02-25 |
1999-06-17 |
E.I. Du Pont De Nemours And Co., Wilmington, Del. |
4-n substituierte sialinsäuren und deren sialoside
|
|
WO1995024176A1
(en)
|
1994-03-07 |
1995-09-14 |
Bioject, Inc. |
Ampule filling device
|
|
US5466220A
(en)
|
1994-03-08 |
1995-11-14 |
Bioject, Inc. |
Drug vial mixing and transfer device
|
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
|
US5622701A
(en)
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
|
DE69534530T2
(de)
|
1994-08-12 |
2006-07-06 |
Immunomedics, Inc. |
Für b-zell-lymphom und leukämiezellen spezifische immunkonjugate und humane antikörper
|
|
US5639635A
(en)
|
1994-11-03 |
1997-06-17 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
|
CA2207869A1
(en)
|
1994-12-02 |
1996-06-06 |
Chiron Corporation |
Method of promoting an immune response with a bispecific antibody
|
|
US5663149A
(en)
|
1994-12-13 |
1997-09-02 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
|
|
US5599302A
(en)
|
1995-01-09 |
1997-02-04 |
Medi-Ject Corporation |
Medical injection system and method, gas spring thereof and launching device using gas spring
|
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US6673533B1
(en)
|
1995-03-10 |
2004-01-06 |
Meso Scale Technologies, Llc. |
Multi-array multi-specific electrochemiluminescence testing
|
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
CN1181720A
(zh)
|
1995-04-25 |
1998-05-13 |
伊萝莉公司 |
可远程编程的存储器材料及其应用
|
|
DE69637481T2
(de)
|
1995-04-27 |
2009-04-09 |
Amgen Fremont Inc. |
Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
|
|
AU2466895A
(en)
|
1995-04-28 |
1996-11-18 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5730723A
(en)
|
1995-10-10 |
1998-03-24 |
Visionary Medical Products Corporation, Inc. |
Gas pressured needle-less injection device and method
|
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
|
US6265150B1
(en)
|
1995-06-07 |
2001-07-24 |
Becton Dickinson & Company |
Phage antibodies
|
|
US5837234A
(en)
|
1995-06-07 |
1998-11-17 |
Cytotherapeutics, Inc. |
Bioartificial organ containing cells encapsulated in a permselective polyether suflfone membrane
|
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
|
AU6505796A
(en)
|
1995-07-26 |
1997-02-26 |
Maxim Pharmaceuticals |
Mucosal delivery of polynucleotides
|
|
DE19544393A1
(de)
|
1995-11-15 |
1997-05-22 |
Hoechst Schering Agrevo Gmbh |
Synergistische herbizide Mischungen
|
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
|
US6027888A
(en)
|
1996-04-05 |
2000-02-22 |
Board Of Regents, The University Of Texas System |
Methods for producing soluble, biologically-active disulfide-bond containing eukaryotic proteins in bacterial cells
|
|
GB9607549D0
(en)
|
1996-04-11 |
1996-06-12 |
Weston Medical Ltd |
Spring-powered dispensing device
|
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
US6340702B1
(en)
|
1996-07-22 |
2002-01-22 |
Sankyo Company, Limited |
Neuraminic acid derivatives, their preparation and their medical use
|
|
US6506564B1
(en)
|
1996-07-29 |
2003-01-14 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
|
TR199901081T2
(xx)
|
1996-11-14 |
1999-08-23 |
Biota Scientific Management Pty.Ltd. |
Y�ntem ve bu y�ntemde kullan�lan yeni bile�imler.
|
|
DE69738539T2
(de)
|
1996-12-03 |
2009-03-26 |
Amgen Fremont Inc. |
Vollkommen humane Antikörper die EGFR binden
|
|
TW555562B
(en)
|
1996-12-27 |
2003-10-01 |
Kirin Brewery |
Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
|
|
US6399071B1
(en)
|
1997-04-18 |
2002-06-04 |
Novartis Ag |
Neoglycoproteins
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
US6083715A
(en)
|
1997-06-09 |
2000-07-04 |
Board Of Regents, The University Of Texas System |
Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
|
|
JPH1135593A
(ja)
|
1997-07-18 |
1999-02-09 |
Daikin Ind Ltd |
2−フルオロフコシル−n−アロイルグルコサミン誘導体及びその中間物、並びにそれらの製造方法
|
|
TW477783B
(en)
|
1997-12-12 |
2002-03-01 |
Gilead Sciences Inc |
Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
|
|
IT1298087B1
(it)
|
1998-01-08 |
1999-12-20 |
Fiderm S R L |
Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
|
|
JP2002507410A
(ja)
|
1998-03-27 |
2002-03-12 |
プロルーム・リミテッド |
ルシフェラーゼ、蛍光タンパク質、ルシフェラーゼおよび蛍光タンパク質をコードする核酸および、診断、高処理スクリーニングおよび新規アイテムにおけるその使用
|
|
CA2323757C
(en)
|
1998-04-02 |
2011-08-02 |
Genentech, Inc. |
Antibody variants and fragments thereof
|
|
PT2180007E
(pt)
|
1998-04-20 |
2013-11-25 |
Roche Glycart Ag |
Engenharia de glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
|
|
US6455571B1
(en)
|
1998-04-23 |
2002-09-24 |
Abbott Laboratories |
Inhibitors of neuraminidases
|
|
DK1308456T3
(da)
|
1998-05-06 |
2007-12-27 |
Genentech Inc |
Antistofoprensning ved ionbytterkromatografi
|
|
US6528286B1
(en)
|
1998-05-29 |
2003-03-04 |
Genentech, Inc. |
Mammalian cell culture process for producing glycoproteins
|
|
JP3773153B2
(ja)
|
1998-05-29 |
2006-05-10 |
独立行政法人理化学研究所 |
シアル酸誘導体
|
|
EP2306195A3
(en)
|
1998-09-18 |
2012-04-25 |
Massachusetts Institute of Technology |
Biological applications of semiconductor nanocrystals
|
|
FR2783523B1
(fr)
*
|
1998-09-21 |
2006-01-20 |
Goemar Lab Sa |
Fuco-oligosaccharides, enzyme pour leur preparation a partir des fucanes, bacterie productrice de l'enzyme et applications des fuco-oligosaccharides a la protection des plantes
|
|
US6696304B1
(en)
|
1999-02-24 |
2004-02-24 |
Luminex Corporation |
Particulate solid phase immobilized protein quantitation
|
|
AUPP913999A0
(en)
|
1999-03-12 |
1999-04-01 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
US7090973B1
(en)
|
1999-04-09 |
2006-08-15 |
Oscient Pharmaceuticals Corporation |
Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics
|
|
US7854934B2
(en)
|
1999-08-20 |
2010-12-21 |
Sloan-Kettering Institute For Cancer Research |
Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
|
|
US6824780B1
(en)
|
1999-10-29 |
2004-11-30 |
Genentech, Inc. |
Anti-tumor antibody compositions and methods of use
|
|
AUPQ422399A0
(en)
|
1999-11-24 |
1999-12-16 |
University Of New South Wales, The |
Method of screening transformed or transfected cells
|
|
US6727356B1
(en)
|
1999-12-08 |
2004-04-27 |
Epoch Pharmaceuticals, Inc. |
Fluorescent quenching detection reagents and methods
|
|
US20020098513A1
(en)
|
2000-02-17 |
2002-07-25 |
Glycominds Ltd. |
Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
|
|
US7019129B1
(en)
|
2000-05-09 |
2006-03-28 |
Biosearch Technologies, Inc. |
Dark quenchers for donor-acceptor energy transfer
|
|
US7863020B2
(en)
|
2000-06-28 |
2011-01-04 |
Glycofi, Inc. |
Production of sialylated N-glycans in lower eukaryotes
|
|
US6514221B2
(en)
|
2000-07-27 |
2003-02-04 |
Brigham And Women's Hospital, Inc. |
Blood-brain barrier opening
|
|
US20020065259A1
(en)
|
2000-08-30 |
2002-05-30 |
Schatzberg Alan F. |
Glucocorticoid blocking agents for increasing blood-brain barrier permeability
|
|
AUPR001000A0
(en)
|
2000-09-08 |
2000-10-05 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
US7034036B2
(en)
|
2000-10-30 |
2006-04-25 |
Pain Therapeutics, Inc. |
Inhibitors of ABC drug transporters at the blood-brain barrier
|
|
US20030083299A1
(en)
|
2000-11-04 |
2003-05-01 |
Ferguson Ian A. |
Non-invasive delivery of polypeptides through the blood-brain barrier
|
|
JP2002153272A
(ja)
|
2000-11-24 |
2002-05-28 |
Inst Of Physical & Chemical Res |
生体分子マイクロアレイ
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
AU2002338446A1
(en)
|
2001-01-23 |
2002-11-05 |
University Of Rochester Medical Center |
Methods of producing or identifying intrabodies in eukaryotic cells
|
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
|
DE10121982B4
(de)
|
2001-05-05 |
2008-01-24 |
Lts Lohmann Therapie-Systeme Ag |
Nanopartikel aus Protein mit gekoppeltem Apolipoprotein E zur Überwindung der Blut-Hirn-Schranke und Verfahren zu ihrer Herstellung
|
|
JP2002371087A
(ja)
|
2001-06-15 |
2002-12-26 |
Mitsubishi Chemicals Corp |
有機ホスホン酸
|
|
AU2002327338A1
(en)
|
2001-07-25 |
2003-02-17 |
New York University |
Use of glycosylceramides as adjuvants for vaccines against infections and cancer
|
|
US20030113316A1
(en)
|
2001-07-25 |
2003-06-19 |
Kaisheva Elizabet A. |
Stable lyophilized pharmaceutical formulation of IgG antibodies
|
|
EP1554572B1
(en)
|
2001-07-25 |
2009-10-14 |
Raptor Pharmaceutical Inc. |
Compositions and methods for modulating blood-brain barrier transport
|
|
CA2455365C
(en)
|
2001-08-03 |
2014-07-29 |
Glycart Biotechnology Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
|
ES2556338T3
(es)
*
|
2001-10-10 |
2016-01-15 |
Novo Nordisk A/S |
Remodelación y glicoconjugación de péptidos
|
|
JP4763237B2
(ja)
|
2001-10-19 |
2011-08-31 |
キャボット コーポレイション |
基板上に導電性電子部品を製造する方法
|
|
AUPR879601A0
(en)
|
2001-11-09 |
2001-12-06 |
Biota Scientific Management Pty Ltd |
Novel chemical compounds and their use
|
|
AU2002352831A1
(en)
|
2001-11-21 |
2003-06-10 |
Paradigm Genetics, Inc. |
Methods and systems for analyzing complex biological systems
|
|
CN100522999C
(zh)
|
2002-02-14 |
2009-08-05 |
免疫医疗公司 |
抗cd20抗体及其融合蛋白和使用方法
|
|
US20030162695A1
(en)
|
2002-02-27 |
2003-08-28 |
Schatzberg Alan F. |
Glucocorticoid blocking agents for increasing blood-brain barrier permeability
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
AU2003219277A1
(en)
|
2002-03-14 |
2003-09-29 |
Medical Research Council |
Intracellular antibodies
|
|
DE60328481D1
(de)
|
2002-05-14 |
2009-09-03 |
Novartis Vaccines & Diagnostic |
Schleimhautapplizierter impfstoff, der das adjuvanz chitosan und menigokokkenantigene enthält
|
|
EP1551865B1
(en)
|
2002-07-08 |
2009-04-22 |
GlaxoSmithKline istrazivacki centar Zagreb d.o.o. |
Hybrid molecules of macrolides with steroidal/non-steroidal anti-inflammatory molecules
|
|
US20080070324A1
(en)
|
2002-07-15 |
2008-03-20 |
Floyd Alton D |
Quantity control device for microscope slide staining assays
|
|
EP1391213A1
(en)
|
2002-08-21 |
2004-02-25 |
Boehringer Ingelheim International GmbH |
Compositions and methods for treating cancer using maytansinoid CD44 antibody immunoconjugates and chemotherapeutic agents
|
|
US20040062682A1
(en)
|
2002-09-30 |
2004-04-01 |
Rakow Neal Anthony |
Colorimetric sensor
|
|
CN101928344B
(zh)
|
2002-10-17 |
2014-08-13 |
根马布股份公司 |
抗cd20的人单克隆抗体
|
|
KR101186210B1
(ko)
|
2002-12-03 |
2012-10-08 |
블랜체트 록펠러 뉴로사이언시즈 인스티튜트 |
혈뇌장벽을 통과하는 물질 수송용 인공 저밀도 지단백질 운반체
|
|
ES2347241T3
(es)
|
2002-12-16 |
2010-10-27 |
Genentech, Inc. |
Variantes de inmunoglobulina y sus utilizaciones.
|
|
AU2004204494B2
(en)
|
2003-01-09 |
2011-09-29 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
EP1587921B1
(en)
*
|
2003-01-22 |
2010-07-28 |
GlycArt Biotechnology AG |
Fusion constructs and use of same to produce antibodies with increased fc receptor binding affinity and effector function
|
|
US8088387B2
(en)
|
2003-10-10 |
2012-01-03 |
Immunogen Inc. |
Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
|
|
AR044388A1
(es)
|
2003-05-20 |
2005-09-07 |
Applied Molecular Evolution |
Moleculas de union a cd20
|
|
US20040259142A1
(en)
|
2003-06-04 |
2004-12-23 |
Imperial College Innovations Limited |
Products and methods
|
|
CA2528669A1
(en)
|
2003-06-09 |
2005-01-20 |
The Regents Of The University Of Michigan |
Compositions and methods for treating and diagnosing cancer
|
|
JP4148844B2
(ja)
|
2003-06-11 |
2008-09-10 |
ソニー・エリクソン・モバイルコミュニケーションズ株式会社 |
情報端末装置及び音声付画像ファイルの出力方法
|
|
EP1648507B1
(en)
*
|
2003-07-24 |
2017-01-25 |
Innate Pharma S.A. |
Methods and compositions for increasing the efficiency of therapeutic antibodies using nk cell potentiating compounds
|
|
JP2007501812A
(ja)
*
|
2003-08-08 |
2007-02-01 |
ノボ ノルディスク アクティーゼルスカブ |
ペプチドのための結合剤として新しい構造上十分に定義された枝分れしたポリマーの合成および適用
|
|
EP1663239A4
(en)
|
2003-09-10 |
2008-07-23 |
Cedars Sinai Medical Center |
KALIUM CHANNEL-MEDIATED FEEDING OF MEDICINES BY THE BLOOD BRAIN BARRIER
|
|
WO2005027990A2
(en)
|
2003-09-15 |
2005-03-31 |
Univ Jefferson |
Implants with attached silylated therapeutic agents
|
|
JP2007522094A
(ja)
|
2003-09-22 |
2007-08-09 |
アシドフィル エルエルシー |
小分子組成物、及びその組成物を使用して薬物効率を高めるための方法
|
|
US7019288B2
(en)
|
2003-09-30 |
2006-03-28 |
Sequenom, Inc. |
Methods of making substrates for mass spectrometry analysis and related devices
|
|
US20050221337A1
(en)
|
2003-10-02 |
2005-10-06 |
Massachusetts Institute Of Technology |
Microarrays and microspheres comprising oligosaccharides, complex carbohydrates or glycoproteins
|
|
HRP20100303T1
(hr)
|
2003-11-05 |
2010-07-31 |
Roche Glycart Ag |
Cd20 antitijela s povećanim afinitetom vezivanja fc receptora i efektorskim djelovanjem
|
|
ES2456325T3
(es)
|
2003-11-06 |
2014-04-22 |
Seattle Genetics, Inc. |
Compuestos de monometilvalina capaces de conjugación con ligandos
|
|
WO2005050224A2
(en)
|
2003-11-13 |
2005-06-02 |
Epitome Biosystems Inc. |
Small molecule and peptide arrays and uses thereof
|
|
JP2007527539A
(ja)
|
2004-03-05 |
2007-09-27 |
ザ スクリプス リサーチ インスティテュート |
ハイスループットグリカンマイクロアレイ
|
|
US20050221397A1
(en)
|
2004-03-30 |
2005-10-06 |
Northern Advancement Center For Science & Technology |
RM2 antigen (beta1,4-GalNAc-disialyl-Lc4) as prostate cancer-associated antigen
|
|
WO2005103081A2
(en)
|
2004-04-20 |
2005-11-03 |
Genmab A/S |
Human monoclonal antibodies against cd20
|
|
ITMI20040928A1
(it)
|
2004-05-07 |
2004-08-07 |
Uni Di Bologna Dipartiment O D |
Procedura per la preparazione di coniugati della doxorubicina con l'albumina umana lattosaminata
|
|
WO2006002382A2
(en)
|
2004-06-24 |
2006-01-05 |
The Scripps Research Institute |
Arrays with cleavable linkers
|
|
DK1771482T3
(da)
|
2004-07-22 |
2014-10-20 |
Genentech Inc |
HER2-antistofsammensætning
|
|
US8022043B2
(en)
|
2004-08-27 |
2011-09-20 |
Albert Einstein College Of Medicine Of Yeshiva University |
Ceramide derivatives as modulators of immunity and autoimmunity
|
|
US20100291537A1
(en)
|
2004-11-16 |
2010-11-18 |
Glauco Souza |
Methods and compositions related to phage-nanoparticle assemblies
|
|
WO2006055925A2
(en)
|
2004-11-19 |
2006-05-26 |
Swiss Federal Institute Of Technology |
Microarrays for analyte detection
|
|
WO2006064983A1
(en)
|
2004-12-14 |
2006-06-22 |
Korea Research Institute Of Bioscience And Biotechnology |
Monoclonal antibody specific human embryonic stem cell
|
|
US7923013B2
(en)
|
2004-12-28 |
2011-04-12 |
The Rockefeller University |
Glycolipids and analogues thereof as antigens for NKT cells
|
|
JP5090928B2
(ja)
|
2004-12-28 |
2012-12-05 |
ザ ロックフェラー ユニバーシティ |
Nkt細胞に対する抗原としての糖脂質及びその類似体
|
|
EP1835937B1
(en)
|
2005-01-06 |
2012-04-11 |
Novo Nordisk A/S |
Compositions and methods for treating viral infection
|
|
US7837990B2
(en)
|
2005-03-28 |
2010-11-23 |
The Rockefeller University |
In vivo expanded NKT cells and methods of use thereof
|
|
EP1865058B1
(en)
|
2005-03-31 |
2011-01-12 |
Biomedics Inc. |
Anti-cd-20 monoclonal antibody
|
|
CN101273063A
(zh)
|
2005-05-24 |
2008-09-24 |
阿维斯塔金格兰技术有限公司 |
用于b细胞淋巴瘤治疗的针对cd20的单克隆抗体的生产方法
|
|
CA2610234A1
(en)
|
2005-06-02 |
2006-12-07 |
Astrazeneca Ab |
Antibodies directed to cd20 and uses thereof
|
|
CN101506238B
(zh)
*
|
2005-06-30 |
2013-11-06 |
森托科尔公司 |
具有提高治疗活性的方法和成分
|
|
JP2007036104A
(ja)
|
2005-07-29 |
2007-02-08 |
Nec Electronics Corp |
半導体装置およびその製造方法
|
|
CA2621236A1
(en)
*
|
2005-08-31 |
2007-03-08 |
Centocor, Inc. |
Host cell lines for production of antibody constant region with enhanced effector function
|
|
WO2007053648A2
(en)
|
2005-10-31 |
2007-05-10 |
The Regents Of The University Of Michigan |
Compositions and methods for treating and diagnosing cancer
|
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
|
US7781203B2
(en)
|
2005-12-29 |
2010-08-24 |
Corning Incorporated |
Supports for assaying analytes and methods of making and using thereof
|
|
US20090060921A1
(en)
*
|
2006-01-17 |
2009-03-05 |
Biolex Therapeutics, Inc. |
Glycan-optimized anti-cd20 antibodies
|
|
EP2001358B1
(en)
|
2006-03-27 |
2016-07-13 |
University Of Maryland, Baltimore |
Glycoprotein synthesis and remodeling by enzymatic transglycosylation
|
|
DE602007006471D1
(de)
|
2006-05-18 |
2010-06-24 |
Veterinaermedizinische Uni Wie |
Nachweisverfahren für grippeviren
|
|
CA2655246A1
(en)
|
2006-06-09 |
2007-12-21 |
University Of Maryland, Baltimore |
Glycosylation engineered antibody therapy
|
|
JP5215298B2
(ja)
|
2006-07-12 |
2013-06-19 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グリコシル化された基質から切断される末端単糖の固相検出
|
|
JP2008025989A
(ja)
|
2006-07-15 |
2008-02-07 |
Keio Gijuku |
局在表面プラズモン共鳴法と質量分析法によるリガンドの分析方法及びそのためのセンサー素子
|
|
CA2660516A1
(en)
|
2006-08-18 |
2008-02-21 |
Oncotherapy Science, Inc. |
Treating or preventing cancers over-expressing reg4 or kiaa0101
|
|
US8444971B2
(en)
|
2006-11-27 |
2013-05-21 |
Diadexus, Inc. |
OVR110 antibody compositions and methods of use
|
|
US8765390B2
(en)
|
2006-12-08 |
2014-07-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Identification and isolation of squamous carcinoma stem cells
|
|
US9239329B2
(en)
|
2006-12-18 |
2016-01-19 |
Japan Science And Technology Agency |
Method of measuring interaction between biomaterial and sugar chain, method of evaluating biomaterial in sugar chain selectivity, method of screening biomaterial, method of patterning biomaterials, and kits for performing these methods
|
|
AU2008206884B2
(en)
|
2007-01-18 |
2012-07-05 |
Glykos Finland Oy |
Novel methods and reagents directed to production of cells
|
|
JP2010516241A
(ja)
|
2007-01-18 |
2010-05-20 |
スオメン プナイネン リスティ,ヴェリパルベル |
新規の特異的細胞結合剤
|
|
US8309354B2
(en)
|
2007-01-22 |
2012-11-13 |
Macrogenics West, Inc. |
Human cancer stem cells
|
|
WO2008103824A1
(en)
|
2007-02-23 |
2008-08-28 |
Chinese Academy Of Inspection And Quarantine (Caiq) |
Sensitivity-enhanced dot-antibody linked immunogold assay for virus detection
|
|
KR101473028B1
(ko)
|
2007-03-07 |
2014-12-15 |
다이이찌 산쿄 가부시키가이샤 |
인플루엔자 치료제
|
|
US20080220988A1
(en)
|
2007-03-07 |
2008-09-11 |
Ada Technologies, Inc. |
Preparing carbohydrate microarrays and conjugated nanoparticles
|
|
DK2308514T3
(da)
|
2007-03-23 |
2013-09-02 |
To Bbb Holding B V |
Konjugater til målrettet lægemiddeltransport gennem blod-hjerne barrieren
|
|
US7943330B2
(en)
|
2007-03-23 |
2011-05-17 |
Academia Sinica |
Tailored glycoproteomic methods for the sequencing, mapping and identification of cellular glycoproteins
|
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
|
EP2144594A4
(en)
|
2007-04-13 |
2012-12-05 |
Academia Sinica |
ALPHA-GALACTOSYL CERAMIDE ANALOGUES AND THEIR USE IN IMMUNOTHERAPIES
|
|
MX2009011500A
(es)
|
2007-04-23 |
2010-01-29 |
Schering Corp |
Anticuerpos anti-mdl-1.
|
|
US8082480B2
(en)
|
2007-06-27 |
2011-12-20 |
Presagis |
Distributed checksum computation
|
|
EP2527435B2
(en)
|
2007-07-12 |
2021-10-13 |
Sangamo BioSciences, Inc. |
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT 8) gene expression
|
|
EP2022848A1
(en)
|
2007-08-10 |
2009-02-11 |
Hubrecht Institut |
A method for identifying, expanding, and removing adult stem cells and cancer stem cells
|
|
CA2697508A1
(en)
|
2007-08-24 |
2009-03-05 |
Tokyo Institute Of Technology |
Method for detecting gynecologic cancer
|
|
US7888337B2
(en)
|
2007-08-31 |
2011-02-15 |
Academia Sinica |
Synthesis of oseltamivir containing phosphonate congeners with anti-influenza activity
|
|
FR2921387B1
(fr)
|
2007-09-26 |
2012-04-20 |
Sanofi Pasteur |
Procede de production du virus de la grippe
|
|
US8647626B2
(en)
|
2007-10-02 |
2014-02-11 |
Avaxia Biologics, Incorporated |
Compositions comprising TNF-specific antibodies for oral delivery
|
|
US20090123439A1
(en)
|
2007-11-09 |
2009-05-14 |
The Jackson Laboratory |
Diagnostic and prognosis methods for cancer stem cells
|
|
CA2710779C
(en)
|
2007-12-31 |
2017-06-20 |
Bayer Schering Pharma Aktiengesellschaft |
Antibodies to tnf.alpha.
|
|
CN106222150A
(zh)
|
2008-03-21 |
2016-12-14 |
丹尼斯科美国公司 |
用于增加生物量水解的富含半纤维素酶的组合物
|
|
WO2009119692A1
(ja)
|
2008-03-25 |
2009-10-01 |
独立行政法人理化学研究所 |
新規糖脂質及びその用途
|
|
CN107561270B
(zh)
|
2008-04-09 |
2019-06-04 |
贝克顿·迪金森公司 |
使用包被的纳米颗粒的灵敏的免疫测定
|
|
US8383554B2
(en)
|
2008-04-14 |
2013-02-26 |
Academia Sinica |
Quantitative microarray of intact glycolipid CD1d interaction and correlation with cell-based cytokine production
|
|
MX2010011598A
(es)
*
|
2008-04-22 |
2010-12-15 |
Univ Rockefeller |
Metodos para identificar compuestos anti-inflamatorios.
|
|
US8906832B2
(en)
|
2008-04-30 |
2014-12-09 |
Academia Sinica |
Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants
|
|
CN102036658A
(zh)
|
2008-05-23 |
2011-04-27 |
香港大学 |
治疗流感的联合疗法
|
|
US20110137570A1
(en)
*
|
2008-05-30 |
2011-06-09 |
Anthony Lapadula |
Methods for structural analysis of glycans
|
|
EP2303286A4
(en)
|
2008-06-16 |
2011-12-28 |
Academia Sinica |
COMPOSITIONS FOR GENERATING IMMUNE REACTIONS SPECIFIC TO GLOBO H AND SSEA3 AND THEIR USES IN CANCER TREATMENT
|
|
JP5216139B2
(ja)
|
2008-06-16 |
2013-06-19 |
アカデミア シニカ |
GloboHおよびその断片に対する抗体のレベルに基づく癌の診断方法
|
|
JP2010014691A
(ja)
|
2008-06-20 |
2010-01-21 |
Igaku Seibutsugaku Kenkyusho:Kk |
腹水中のメソテリン及び/又は巨核球増強因子を検出するための方法、キット、試薬及び装置
|
|
US20100003674A1
(en)
|
2008-07-03 |
2010-01-07 |
Cope Frederick O |
Adult stem cells, molecular signatures, and applications in the evaluation, diagnosis, and therapy of mammalian conditions
|
|
US7928077B2
(en)
|
2008-07-11 |
2011-04-19 |
Academia Sinica |
Alpha-galactosyl ceramide analogs and their use as immunotherapies
|
|
JP5986745B2
(ja)
|
2008-07-15 |
2016-09-06 |
アカデミア シニカAcademia Sinica |
Ptfe様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法
|
|
US20100022916A1
(en)
|
2008-07-24 |
2010-01-28 |
Javanbakhsh Esfandiari |
Method and Apparatus for Collecting and Preparing Biological Samples for Testing
|
|
GB0816679D0
(en)
|
2008-09-11 |
2008-10-22 |
Univ Bath |
Compounds for treating viral infections
|
|
WO2010036443A1
(en)
|
2008-09-26 |
2010-04-01 |
Eureka Therapeutics, Inc. |
Cell lines and proteins with variant glycosylation pattern
|
|
US10369204B2
(en)
*
|
2008-10-02 |
2019-08-06 |
Dako Denmark A/S |
Molecular vaccines for infectious disease
|
|
ES2582208T3
(es)
|
2008-10-27 |
2016-09-09 |
Sapporo Medical University |
Marcador molecular para células madre cancerosas
|
|
CA2742990A1
(en)
*
|
2008-11-17 |
2010-05-20 |
Genentech, Inc. |
Method and formulation for reducing aggregation of a macromolecule under physiological conditions
|
|
JP2012518419A
(ja)
*
|
2009-02-25 |
2012-08-16 |
メルク・シャープ・エンド・ドーム・コーポレイション |
糖操作酵母ピチア・パストリスにおけるガラクトース同化経路の代謝操作
|
|
DK2411528T3
(en)
|
2009-03-27 |
2015-12-14 |
Academia Sinica |
ALFA-SELECTIVE SIALYLPHOSPHATDONORER MAKING SIALOSIDER AND sialoside arrays FOR DETECTION OF INFLUENZA
|
|
SG175188A1
(en)
*
|
2009-05-04 |
2011-11-28 |
Abbott Biotech Ltd |
Stable high protein concentration formulations of human anti-tnf-alpha-antibodies
|
|
WO2011005756A1
(en)
|
2009-07-06 |
2011-01-13 |
Puretech Ventures, Llc |
Delivery of agents targeted to microbiota niches
|
|
BR112012001061B8
(pt)
|
2009-07-15 |
2021-05-25 |
Univ British Columbia |
glicosídeos 2,3-fluorados como inibidores de neuraminidase, seu método de preparação, composição farmacêutica que os compreende e embalagem comercial
|
|
KR20120104158A
(ko)
|
2009-07-22 |
2012-09-20 |
엔즌 파마슈티칼스, 인코포레이티드 |
7-에틸-10-히드록시캠토테신의 다분지형 중합 컨쥬게이트와 her2 수용체 길항제를 병용하여 her2 양성 암을 치료하는 방법
|
|
WO2011031236A1
(en)
|
2009-09-14 |
2011-03-17 |
Thailand Excellence Center For Tissue Engineering |
Phytochemical compositions including xanthones for anti-inflammatory, anti-cytokine storm, and other uses
|
|
US10087236B2
(en)
*
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
|
JPWO2011074621A1
(ja)
|
2009-12-18 |
2013-04-25 |
株式会社医学生物学研究所 |
メソセリン(msln)に対する抗体及びその用途
|
|
EP2347769A1
(en)
|
2010-01-20 |
2011-07-27 |
Glycotope GmbH |
Cancer stem cell markers and uses thereof
|
|
SG182823A1
(en)
|
2010-02-11 |
2012-09-27 |
Alexion Pharma Inc |
Therapeutic methods using an ti-cd200 antibodies
|
|
KR101930961B1
(ko)
|
2010-02-24 |
2018-12-19 |
머크 샤프 앤드 돔 코포레이션 |
피키아 파스토리스에서 생산된 치료 당단백질 상의 n-글리코실화 부위 점유를 증가시키는 방법
|
|
HUE046360T2
(hu)
|
2010-03-12 |
2020-03-30 |
Debiopharm Int Sa |
CD37-kötõ molekulák és azok immunkonjugátumai
|
|
US10338069B2
(en)
|
2010-04-12 |
2019-07-02 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
|
WO2011130624A2
(en)
|
2010-04-16 |
2011-10-20 |
Immune Disease Institute, Inc. |
Sustained polypeptide expression from synthetic, modified rnas and uses thereof
|
|
AU2011250970B2
(en)
|
2010-05-10 |
2016-12-15 |
Sinica, Academia |
Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses
|
|
WO2011145957A1
(en)
|
2010-05-20 |
2011-11-24 |
Auckland Uniservices Limited |
Agents and methods for detection and/or imaging of hypoxia
|
|
AU2011258425B2
(en)
*
|
2010-05-27 |
2015-12-10 |
Merck Sharp & Dohme Llc |
Method for preparing antibodies having improved properties
|
|
MX2013002270A
(es)
*
|
2010-08-26 |
2013-05-14 |
Abbvie Inc |
Inmonoglubinas de dominio variable doble y usos de las mismas.
|
|
GB201015569D0
(en)
|
2010-09-16 |
2010-10-27 |
Medical Res Council |
Blood assay for prions
|
|
WO2012082635A1
(en)
|
2010-12-13 |
2012-06-21 |
Ancora Pharmaceuticals, Inc. |
Synthetic oligosaccharide group a streptococcus
|
|
ES2654382T3
(es)
|
2011-01-05 |
2018-02-13 |
National Taiwan University |
Método para la preparación de glucoesfingolípidos
|
|
JP2014509323A
(ja)
|
2011-02-28 |
2014-04-17 |
マックマスター ユニヴァーシティ |
ドーパミン受容体遮断薬による癌の処置
|
|
US10851174B2
(en)
|
2011-03-03 |
2020-12-01 |
University Of Maryland, Baltimore |
Core fucosylated glycopeptides and glycoproteins: chemoenzymatic synthesis and uses thereof
|
|
EP2714732A4
(en)
*
|
2011-05-25 |
2014-12-10 |
Merck Sharp & Dohme |
PROCESS FOR PREPARING FC-CONTAINING POLYPEPTIDES WITH IMPROVED PROPERTIES
|
|
SI2734545T1
(sl)
*
|
2011-07-18 |
2019-06-28 |
Institute For Research In Biomedicine |
Protitelesa, ki nevtralizirajo virus influence A in njihova uporaba
|
|
JP5795067B2
(ja)
|
2011-07-21 |
2015-10-14 |
京セラ株式会社 |
照明装置、イメージセンサヘッドおよびこれを備える読取装置
|
|
TWI601727B
(zh)
|
2011-08-12 |
2017-10-11 |
日產化學工業股份有限公司 |
三環雜環化合物及jak(傑納斯激酶)抑制劑
|
|
WO2013066761A1
(en)
|
2011-10-31 |
2013-05-10 |
Merck Sharp & Dohme Corp. |
Method for preparing antibodies having improved properties
|
|
US20140302028A1
(en)
|
2011-11-18 |
2014-10-09 |
Merck Sharp & Dohme Corp. |
Fc containing polypeptides having increased anti-inflammatory properties and increased fcrn binding
|
|
EP2604281B1
(en)
|
2011-12-14 |
2014-07-30 |
Centre National de la Recherche Scientifique (CNRS) |
Clicked somatostatin conjugated analogs for biological applications
|
|
US9637465B2
(en)
|
2012-01-19 |
2017-05-02 |
The University Of British Columbia |
3′ Equatorial-fluorine-substituted neuraminidase inhibitor compounds, compositions and methods for the use thereof as anti-virals
|
|
GB201201314D0
(en)
|
2012-01-26 |
2012-03-07 |
Isis Innovation |
Composition
|
|
IN2014DN06806A
(enExample)
|
2012-02-10 |
2015-05-22 |
Univ Maryland |
|
|
WO2013130603A1
(en)
|
2012-02-27 |
2013-09-06 |
Board Of Regents, The University Of Texas System |
Ganglioside gd2 as a marker and target on cancer stem cells
|
|
EP2833915A1
(en)
|
2012-04-02 |
2015-02-11 |
Merrimack Pharmaceuticals, Inc. |
Dosage and administration of monospecific and bispecific anti-igf-1r and anti-erbb3 antibodies
|
|
WO2013151649A1
(en)
|
2012-04-04 |
2013-10-10 |
Sialix Inc |
Glycan-interacting compounds
|
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
|
WO2013181585A2
(en)
|
2012-06-01 |
2013-12-05 |
Momenta Pharmaceuticals, Inc. |
Methods related to adalimumab
|
|
AU2013306098A1
(en)
|
2012-08-18 |
2015-02-12 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
|
TWI510627B
(zh)
|
2012-08-20 |
2015-12-01 |
中央研究院 |
寡醣之大規模酵素合成
|
|
US9547009B2
(en)
|
2012-08-21 |
2017-01-17 |
Academia Sinica |
Benzocyclooctyne compounds and uses thereof
|
|
WO2014070957A1
(en)
|
2012-10-30 |
2014-05-08 |
Esperance Pharmaceuticals, Inc. |
Antibody/drug conjugates and methods of use
|
|
CN110669136A
(zh)
*
|
2012-11-05 |
2020-01-10 |
全药工业株式会社 |
抗体或抗体组合物的制备方法
|
|
WO2014078373A1
(en)
|
2012-11-13 |
2014-05-22 |
Iogenetics, Llc |
Antimicrobial compositions
|
|
CN103045647A
(zh)
*
|
2012-11-29 |
2013-04-17 |
大连大学 |
核心岩藻糖基转移酶基因沉默细胞模型的建立及鉴定方法
|
|
GB201305986D0
(en)
|
2013-04-03 |
2013-05-15 |
Asociaci N Ct De Investigaci N Cooperativa En Biomateriales |
Synthesis and use of isotopically-labelled glycans
|
|
WO2014167126A2
(en)
|
2013-04-13 |
2014-10-16 |
Universidade De Coimbra |
Platform for targeted delivery to stem cells and tumor cells and methods thereof
|
|
CN104225616A
(zh)
|
2013-06-08 |
2014-12-24 |
中南大学 |
一种靶向卵巢癌干细胞的抗肿瘤生物制剂
|
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
|
WO2014210564A1
(en)
|
2013-06-27 |
2014-12-31 |
Academia Sinica |
Glycan conjugates and use thereof
|
|
TWI599370B
(zh)
*
|
2013-07-26 |
2017-09-21 |
中央研究院 |
靈芝多醣誘發之抗體介導抗腫瘤活性
|
|
JP6553042B2
(ja)
|
2013-09-05 |
2019-07-31 |
ブイアイビー ブイゼットダブリュVib Vzw |
変更されたグリコシル化パターンを有するFc含有分子を産生する細胞並びにその方法及び使用
|
|
AU2014317889B2
(en)
|
2013-09-06 |
2020-03-05 |
Academia Sinica |
Human iNKT cell activation using glycolipids with altered glycosyl groups
|
|
US20160201132A1
(en)
|
2013-09-12 |
2016-07-14 |
Teva Pharmaceutical Industries Ltd. |
Gene expression biomarkers of laquinimod responsiveness
|
|
CN103436627B
(zh)
|
2013-09-13 |
2016-02-03 |
四川大学华西医院 |
一种恶性乳腺癌干细胞的筛查试剂盒
|
|
US20160215061A1
(en)
|
2013-10-08 |
2016-07-28 |
Merck Sharp & Dohme Corp. |
Fc CONTAINING POLYPEPTIDES HAVING INCREASED BINDING TO FcGammaRIIB
|
|
TW201620939A
(zh)
|
2014-01-16 |
2016-06-16 |
中央研究院 |
治療及檢測癌症之組合物及方法
|
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
TWI682033B
(zh)
*
|
2014-03-17 |
2020-01-11 |
泉盛生物科技股份有限公司 |
製造具有經修飾的糖苷化作用之重組糖蛋白之方法
|
|
TWI687428B
(zh)
|
2014-03-27 |
2020-03-11 |
中央研究院 |
反應性標記化合物及其用途
|
|
AU2015267051B2
(en)
|
2014-05-27 |
2022-03-17 |
Academia Sinica |
Fucosidase from bacteroides and methods using the same
|
|
AU2015267047A1
(en)
*
|
2014-05-27 |
2017-01-05 |
Academia Sinica |
Anti-CD20 glycoantibodies and uses thereof
|
|
JP7062361B2
(ja)
|
2014-05-27 |
2022-05-06 |
アカデミア シニカ |
抗her2糖操作抗体群およびその使用
|
|
US10118969B2
(en)
*
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
|
WO2015184001A1
(en)
*
|
2014-05-28 |
2015-12-03 |
Academia Sinica |
Anti-tnf-alpha glycoantibodies and uses thereof
|
|
US10273295B2
(en)
|
2014-08-19 |
2019-04-30 |
Miltenyi Biotec Gmbh |
Chimeric antigen receptor specific for SSEA4 antigen
|
|
US10155823B2
(en)
|
2014-08-22 |
2018-12-18 |
Academia Sinica |
Glycan conjugates and use thereof
|
|
US9879042B2
(en)
|
2014-09-08 |
2018-01-30 |
Academia Sinica |
Human iNKT cell activation using glycolipids
|
|
EP3191524A4
(en)
|
2014-09-12 |
2018-05-30 |
The Regents of The University of California |
Macropinocytosing human anti-cd46 antibodies and targeted cancer therapeutics
|
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
|
WO2016118090A1
(en)
|
2015-01-23 |
2016-07-28 |
Agency For Science, Technology And Research |
Cancer specific antigen-binding proteins
|
|
AU2015378564A1
(en)
|
2015-01-24 |
2017-07-13 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
|
ES2901173T3
(es)
*
|
2015-01-30 |
2022-03-21 |
Academia Sinica |
Composiciones y procedimientos relacionados con glicoformas universales para una eficacia de anticuerpos anti-SSEA4 mejorada
|
|
US20170283878A1
(en)
|
2015-12-11 |
2017-10-05 |
Academia Sinica |
Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers
|
|
CN109195996A
(zh)
|
2016-03-08 |
2019-01-11 |
中央研究院 |
N-聚醣及其阵列的模组化合成方法
|
|
KR20180121786A
(ko)
|
2016-03-29 |
2018-11-08 |
오비아이 파머 인코퍼레이티드 |
항체, 제약 조성물 및 방법
|
|
KR102588027B1
(ko)
|
2016-08-22 |
2023-10-12 |
초 파마 인크. |
항체, 결합 단편 및 사용 방법
|
|
US10000747B2
(en)
|
2016-08-24 |
2018-06-19 |
Academia Sinica |
Endoglycosidase mutants for glycoprotein remodeling and methods of using it
|
|
CA3044274A1
(en)
|
2016-11-21 |
2018-05-24 |
Obi Pharma, Inc. |
Conjugated biological molecules, pharmaceutical compositions and methods
|
|
US11203645B2
(en)
|
2018-06-27 |
2021-12-21 |
Obi Pharma, Inc. |
Glycosynthase variants for glycoprotein engineering and methods of use
|