DK1042359T3 - k-Opioidreceptorpeptider - Google Patents
k-OpioidreceptorpeptiderInfo
- Publication number
- DK1042359T3 DK1042359T3 DK98964224T DK98964224T DK1042359T3 DK 1042359 T3 DK1042359 T3 DK 1042359T3 DK 98964224 T DK98964224 T DK 98964224T DK 98964224 T DK98964224 T DK 98964224T DK 1042359 T3 DK1042359 T3 DK 1042359T3
- Authority
- DK
- Denmark
- Prior art keywords
- opioid peptides
- opioid
- peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/997,208 US5965701A (en) | 1997-12-23 | 1997-12-23 | Kappa receptor opioid peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1042359T3 true DK1042359T3 (da) | 2005-11-28 |
Family
ID=25543752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98964224T DK1042359T3 (da) | 1997-12-23 | 1998-12-22 | k-Opioidreceptorpeptider |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5965701A (cs) |
| EP (1) | EP1042359B1 (cs) |
| JP (1) | JP4275852B2 (cs) |
| KR (1) | KR100629548B1 (cs) |
| CN (1) | CN1154655C (cs) |
| AR (1) | AR014167A1 (cs) |
| AT (1) | ATE301670T1 (cs) |
| AU (1) | AU747806B2 (cs) |
| BR (2) | BRPI9814499B8 (cs) |
| CA (1) | CA2315878C (cs) |
| CR (1) | CR5936A (cs) |
| CZ (1) | CZ297281B6 (cs) |
| DE (1) | DE69831176T2 (cs) |
| DK (1) | DK1042359T3 (cs) |
| EE (1) | EE04440B1 (cs) |
| ES (1) | ES2247735T3 (cs) |
| HK (1) | HK1029349A1 (cs) |
| HR (1) | HRP20000415B1 (cs) |
| HU (1) | HU227640B1 (cs) |
| IL (3) | IL136742A0 (cs) |
| MY (1) | MY117542A (cs) |
| NO (1) | NO327080B1 (cs) |
| NZ (1) | NZ505183A (cs) |
| PL (1) | PL195842B1 (cs) |
| PT (1) | PT1042359E (cs) |
| RU (1) | RU2217437C2 (cs) |
| SK (1) | SK286135B6 (cs) |
| TR (1) | TR200001985T2 (cs) |
| TW (1) | TW580502B (cs) |
| UA (1) | UA68366C2 (cs) |
| UY (1) | UY25327A1 (cs) |
| WO (1) | WO1999032510A1 (cs) |
| ZA (1) | ZA9811801B (cs) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| AU1623801A (en) * | 1999-11-19 | 2001-05-30 | Palatin Technologies, Inc. | Opioid metallopeptide compositions and methods |
| DE10116978A1 (de) | 2001-04-05 | 2002-10-10 | Merck Patent Gmbh | Kappa-Opiatagonisten für die Behandlung von Erkrankungen der Blase |
| CN1283317C (zh) * | 2001-05-08 | 2006-11-08 | 东丽株式会社 | 类鸦片κ受体激动性化合物在制备治疗败血症的药物中的应用 |
| CA2479751C (en) | 2002-03-20 | 2008-06-03 | Trent Poole | Inhalation apparatus |
| CA2575692C (en) | 2004-08-20 | 2014-10-14 | Mannkind Corporation | Catalysis of diketopiperazine synthesis |
| JP4990142B2 (ja) | 2004-08-23 | 2012-08-01 | マンカインド コーポレイション | 薬物送達のためのジケトピペラジン塩、ジケトモルホリン塩、又はジケトジオキサン塩 |
| ES2640282T3 (es) | 2005-09-14 | 2017-11-02 | Mannkind Corporation | Método de formulación de fármacos basado en el aumento de la afinidad de superficies de micropartículas cristalinas para agentes activos |
| CN101389348A (zh) | 2006-02-22 | 2009-03-18 | 曼金德公司 | 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法 |
| JP2009538316A (ja) * | 2006-05-26 | 2009-11-05 | カラ セラピューティクス インコーポレイテッド | κオピオイド受容体ペプチドのＮ−オキシド |
| JP2009538310A (ja) * | 2006-05-26 | 2009-11-05 | カラ セラピューティクス インコーポレイテッド | 哺乳動物におけるプロラクチンを上昇させる方法 |
| US7713937B2 (en) * | 2006-11-10 | 2010-05-11 | Cara Therapeutics, Inc. | Synthetic peptide amides and dimeric forms thereof |
| US7842662B2 (en) | 2006-11-10 | 2010-11-30 | Cara Therapeutics, Inc. | Synthetic peptide amide dimers |
| US8236766B2 (en) * | 2006-11-10 | 2012-08-07 | Cara Therapeutics, Inc. | Uses of synthetic peptide amides |
| CA2667155C (en) | 2006-11-10 | 2016-05-10 | Cara Therapeutics, Inc. | Synthetic peptide amides |
| US8906859B2 (en) * | 2006-11-10 | 2014-12-09 | Cera Therapeutics, Inc. | Uses of kappa opioid synthetic peptide amides |
| WO2008077194A1 (en) * | 2006-12-22 | 2008-07-03 | Xenome Ltd | Receptor agonists |
| RU2468832C2 (ru) | 2008-06-13 | 2012-12-10 | Маннкайнд Корпорейшн | Ингалятор для сухого порошка и система для доставки лекарственных средств |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| CN102065942B (zh) | 2008-06-20 | 2013-12-11 | 曼金德公司 | 用于对吸入工作进行实时描绘的交互式设备和方法 |
| TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| JP5859433B2 (ja) | 2009-06-12 | 2016-02-10 | マンカインド コーポレイション | 規定された比表面積を有するジケトピペラジン微粒子 |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| JP6385673B2 (ja) | 2010-06-21 | 2018-09-05 | マンカインド コーポレイション | 乾燥粉末薬物送達システム |
| BR122020008875B8 (pt) | 2011-04-01 | 2022-12-06 | Mannkind Corp | Embalagem de bolha e método de fabricação de uma embalagem de bolhas |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| JP6018640B2 (ja) * | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
| US9802012B2 (en) | 2012-07-12 | 2017-10-31 | Mannkind Corporation | Dry powder drug delivery system and methods |
| US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
| KR102391750B1 (ko) | 2013-03-15 | 2022-04-28 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
| JP6491658B2 (ja) | 2013-07-18 | 2019-03-27 | マンカインド コーポレイション | 熱安定性乾燥粉末医薬組成物及び方法 |
| WO2015021064A1 (en) | 2013-08-05 | 2015-02-12 | Mannkind Corporation | Insufflation apparatus and methods |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| EP3162810B1 (en) * | 2014-06-26 | 2019-02-13 | Maruishi Pharmaceutical Co., Ltd. | Method for producing synthetic pentapeptide |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| EP3294315A2 (en) | 2015-05-11 | 2018-03-21 | Cadila Healthcare Limited | Novel short-chain peptides as kappa opioid receptors (kor) agonist |
| CN107098876B (zh) * | 2016-02-23 | 2021-04-06 | 江苏恒瑞医药股份有限公司 | 苯基丙酰胺类衍生物、其制备方法及其在医药上的应用 |
| JP6794602B2 (ja) | 2016-09-27 | 2020-12-02 | シチュアン ケルン−バイオテック バイオファーマシューティカル カンパニー リミテッド | ポリアミド化合物及びその使用 |
| ES2905164T3 (es) * | 2017-07-21 | 2022-04-07 | Sichuan Haisco Pharmaceutical Co Ltd | Compuesto de amida peptídico y método de preparación y uso médico del mismo |
| US11180530B2 (en) | 2017-12-06 | 2021-11-23 | Jiangsu Hengrui Medicine Co., Ltd. | Salt of phenylpropionamide derivative and preparation method therefor |
| TW202015716A (zh) | 2018-05-16 | 2020-05-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 一種ｋｏｒ受體激動劑醫藥組成物 |
| CN114127086B (zh) * | 2019-07-25 | 2023-10-20 | 四川海思科制药有限公司 | 氘代肽酰胺类化合物及其制备方法和在医药上的用途 |
| CN114127085B (zh) * | 2019-07-25 | 2024-08-13 | 西藏海思科制药有限公司 | 一种肽酰胺盐及其制备方法和在医药上的用途 |
| CN114615976A (zh) * | 2019-08-07 | 2022-06-10 | 人福医药美国公司 | κ阿片受体肽酰胺激动剂 |
| AU2020454871A1 (en) | 2020-06-25 | 2023-01-19 | Humanwell Pharmaceutical US | Peptides for treatment of medical disorders |
| WO2023278843A2 (en) | 2021-07-02 | 2023-01-05 | Acer Therapeutics, Inc. | Solid forms of osanetant |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2013689B (en) * | 1977-12-15 | 1982-03-24 | Reckitt & Colmann Prod Ltd | Compounds |
| GB8801304D0 (en) * | 1988-01-21 | 1988-02-17 | Ici Plc | Diamine compounds |
| US5367053A (en) * | 1993-05-19 | 1994-11-22 | Houghten Pharmaceuticals, Inc. | Opioid peptide inhibitors |
| US5610271A (en) * | 1995-06-07 | 1997-03-11 | Torrey Pines Institute For Molecular Studies | Kappa receptor selective opioid peptides |
-
1997
- 1997-12-23 US US08/997,208 patent/US5965701A/en not_active Expired - Lifetime
-
1998
- 1998-12-22 MY MYPI98005818A patent/MY117542A/en unknown
- 1998-12-22 CZ CZ20002382A patent/CZ297281B6/cs not_active IP Right Cessation
- 1998-12-22 NZ NZ505183A patent/NZ505183A/en not_active IP Right Cessation
- 1998-12-22 BR BRPI9814499A patent/BRPI9814499B8/pt unknown
- 1998-12-22 IL IL13674298A patent/IL136742A0/xx active IP Right Grant
- 1998-12-22 DE DE69831176T patent/DE69831176T2/de not_active Expired - Lifetime
- 1998-12-22 AU AU19402/99A patent/AU747806B2/en not_active Ceased
- 1998-12-22 RU RU2000119773/04A patent/RU2217437C2/ru active
- 1998-12-22 ZA ZA9811801A patent/ZA9811801B/xx unknown
- 1998-12-22 BR BRPI9814499-5A patent/BR9814499B1/pt not_active IP Right Cessation
- 1998-12-22 EE EEP200000370A patent/EE04440B1/xx not_active IP Right Cessation
- 1998-12-22 JP JP2000525447A patent/JP4275852B2/ja not_active Expired - Lifetime
- 1998-12-22 AT AT98964224T patent/ATE301670T1/de active
- 1998-12-22 KR KR1020007006936A patent/KR100629548B1/ko not_active IP Right Cessation
- 1998-12-22 ES ES98964224T patent/ES2247735T3/es not_active Expired - Lifetime
- 1998-12-22 SK SK960-2000A patent/SK286135B6/sk not_active IP Right Cessation
- 1998-12-22 DK DK98964224T patent/DK1042359T3/da active
- 1998-12-22 PT PT98964224T patent/PT1042359E/pt unknown
- 1998-12-22 CR CR5936A patent/CR5936A/es unknown
- 1998-12-22 HU HU0100626A patent/HU227640B1/hu not_active IP Right Cessation
- 1998-12-22 UA UA2000063810A patent/UA68366C2/uk unknown
- 1998-12-22 WO PCT/US1998/027282 patent/WO1999032510A1/en active IP Right Grant
- 1998-12-22 EP EP98964224A patent/EP1042359B1/en not_active Expired - Lifetime
- 1998-12-22 CA CA2315878A patent/CA2315878C/en not_active Expired - Lifetime
- 1998-12-22 CN CNB98812582XA patent/CN1154655C/zh not_active Expired - Lifetime
- 1998-12-22 TR TR2000/01985T patent/TR200001985T2/xx unknown
- 1998-12-22 PL PL98341308A patent/PL195842B1/pl not_active IP Right Cessation
- 1998-12-23 AR ARP980106652A patent/AR014167A1/es active IP Right Grant
- 1998-12-23 UY UY25327A patent/UY25327A1/es unknown
-
1999
- 1999-02-10 TW TW087121390A patent/TW580502B/zh not_active IP Right Cessation
-
2000
- 2000-06-12 IL IL136742A patent/IL136742A/en not_active IP Right Cessation
- 2000-06-20 HR HR20000415A patent/HRP20000415B1/xx not_active IP Right Cessation
- 2000-06-21 NO NO20003245A patent/NO327080B1/no not_active IP Right Cessation
- 2000-11-28 HK HK00107625A patent/HK1029349A1/xx not_active IP Right Cessation
-
2006
- 2006-10-05 IL IL178471A patent/IL178471A0/en unknown
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