DE60231938D1 - Partikel auf Basis von Polyhydroxyalkanoat und Verfahren zu deren Herstellung - Google Patents

Partikel auf Basis von Polyhydroxyalkanoat und Verfahren zu deren Herstellung

Info

Publication number
DE60231938D1
DE60231938D1 DE60231938T DE60231938T DE60231938D1 DE 60231938 D1 DE60231938 D1 DE 60231938D1 DE 60231938 T DE60231938 T DE 60231938T DE 60231938 T DE60231938 T DE 60231938T DE 60231938 D1 DE60231938 D1 DE 60231938D1
Authority
DE
Germany
Prior art keywords
polyhydroxyalkanoate
preparation
particles based
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60231938T
Other languages
English (en)
Inventor
Tetsuya Yano
Tsuyoshi Nomoto
Shinya Kozaki
Tsutomu Honma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Canon Inc
Original Assignee
Canon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canon Inc filed Critical Canon Inc
Application granted granted Critical
Publication of DE60231938D1 publication Critical patent/DE60231938D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6925—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a microcapsule, nanocapsule, microbubble or nanobubble
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Nanotechnology (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Emergency Medicine (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Cosmetics (AREA)
DE60231938T 2001-07-10 2002-07-10 Partikel auf Basis von Polyhydroxyalkanoat und Verfahren zu deren Herstellung Expired - Lifetime DE60231938D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2001210041 2001-07-10
JP2001210040 2001-07-10
JP2001210043 2001-07-10
JP2001210055 2001-07-10

Publications (1)

Publication Number Publication Date
DE60231938D1 true DE60231938D1 (de) 2009-05-28

Family

ID=27482422

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60231938T Expired - Lifetime DE60231938D1 (de) 2001-07-10 2002-07-10 Partikel auf Basis von Polyhydroxyalkanoat und Verfahren zu deren Herstellung

Country Status (5)

Country Link
US (1) US7615233B2 (de)
EP (1) EP1275378B1 (de)
KR (1) KR100521526B1 (de)
CN (1) CN1278675C (de)
DE (1) DE60231938D1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3673711B2 (ja) * 1999-12-27 2005-07-20 キヤノン株式会社 ポリヒドロキシアルカノエートおよび微生物を利用するその製造方法
JP2003012957A (ja) * 2001-04-27 2003-01-15 Canon Inc ポリヒドロキシアルカノエートからなるマイクロカプセル化顔料含有カラーフィルタ用着色組成物
US7153622B2 (en) * 2001-04-27 2006-12-26 Canon Kabushiki Kaisha Electrostatic charge image developing toner, producing method therefor, image forming method and image forming apparatus utilizing the toner, construct and method for making the construct
JP2004331750A (ja) * 2003-05-02 2004-11-25 Canon Inc ポリヒドロキシアルカノエートを含有する磁性構造体及びその製造方法ならびにその用途
WO2004097417A1 (en) * 2003-05-02 2004-11-11 Canon Kabushiki Kaisha Structured construct and producing method therefor
JP4429105B2 (ja) * 2003-08-19 2010-03-10 キヤノン株式会社 有機物固定化構造体及びその製造方法、ペプチド及びｄｎａ
WO2005078018A1 (en) * 2004-02-11 2005-08-25 Michigan State University Anhydride functionalized polyhydroxyalkanoates, preparation and use thereof
NZ551241A (en) * 2004-05-14 2010-08-27 Emisphere Tech Inc Aryl ketone compounds and compositions for delivering active agents
JP2006204257A (ja) 2005-01-31 2006-08-10 Canon Inc ポリヒドロキシアルカノエート合成酵素遺伝子の破壊されたポリヒドロキシアルカノエート生産菌の同質遺伝子系統、またこれを利用したポリヒドロキシアルカノエート生産方法
JP2006204258A (ja) * 2005-01-31 2006-08-10 Canon Inc 新規ポリヒドロキシアルカノエート合成微生物及びそれを用いたポリヒドロキシアルカノエートの製造方法
JP2006204255A (ja) * 2005-01-31 2006-08-10 Canon Inc アセチル−ＣｏＡアシルトランスフェラーゼ遺伝子破壊ポリヒドロキシアルカノエート生産菌、またこれを利用したポリヒドロキシアルカノエート生産方法
WO2006129843A2 (en) 2005-05-31 2006-12-07 Canon Kabushiki Kaisha Bispecific capturing molecule
US7875465B2 (en) 2005-05-31 2011-01-25 Canon Kabushiki Kaisha Target substance capturing molecule
JP2006333825A (ja) * 2005-06-03 2006-12-14 Canon Inc 標的物質捕捉用タンパク質の製造方法及びその構成材料の選択方法
FR2893325B1 (fr) * 2005-11-15 2010-04-02 Arkema Procede de preparation de polyhydroxyalkanoates polymeres ainsi obtenus, compositions les comprenant et leurs utilisations
JP2007163185A (ja) * 2005-12-09 2007-06-28 Canon Inc 酵素電極
JP2007163268A (ja) * 2005-12-13 2007-06-28 Canon Inc 酵素電極
US20090233280A1 (en) * 2005-12-28 2009-09-17 Canon Kabushiki Kaisha Method of acquiring information regarding base sequence and information reading device for the same
WO2007092633A2 (en) * 2006-02-09 2007-08-16 Elevance Renewable Sciences, Inc. Antimicrobial compositions, methods and systems
US7951232B2 (en) * 2006-02-09 2011-05-31 Elevance Renewable Sciences, Inc. Surface coating compositions and methods
JP2008054521A (ja) * 2006-08-29 2008-03-13 Canon Inc 細胞培養処理装置及び細胞培養処理方法
JP5196760B2 (ja) * 2006-10-27 2013-05-15 一般財団法人 九州医療資源財団 Ｗ／ｏ／ｗ型エマルジョン組成物
US20080227664A1 (en) * 2007-03-16 2008-09-18 Canon Kabushiki Kaisha Cell array structural body and cell array
JP2010524675A (ja) * 2007-04-26 2010-07-22 ビーエーエスエフ ソシエタス・ヨーロピア マイクロカプセルの酵素的製造法
CN101951895B (zh) * 2008-02-18 2013-11-06 Csir公司 药物给药用的纳米粒子载体及其制备方法
US8093060B2 (en) * 2008-02-28 2012-01-10 Canon Kabushiki Kaisha Multisite phosphorylated peptide (protein) recognizing compound and detection method, imaging method, alzheimer's disease diagnosing method and reagent kit using the same
US20100018674A1 (en) * 2008-07-22 2010-01-28 Donald John Enzinna Reservoir with moveable partition for quick recovery
US20110230343A1 (en) * 2008-10-24 2011-09-22 Basf Se Method for the Manufacture of Microparticles Comprising an Effect Substance
US20110243850A1 (en) 2008-12-25 2011-10-06 Canon Kabushiki Kaisha Probe for a biological specimen and labelling method and screening method using the probe
CN101733051B (zh) * 2010-01-06 2012-06-13 东华大学 硅水凝胶互穿网络(ipn)球的制备方法
US8491908B2 (en) 2010-06-01 2013-07-23 Canon Kabushiki Kaisha Composite particle, contrast agent for photoacoustic imaging, and method for producing the composite particle
US20140079642A1 (en) * 2011-01-24 2014-03-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Nanoparticles based for dermal and systemic delivery of drugs
KR101344660B1 (ko) * 2012-03-09 2013-12-24 경상대학교산학협력단 칼슘 용기, 칼슘 킬레이트화된 ｐｈａ 미립체 및 이를 포함하는 미생물
EP2920290B1 (de) 2012-11-19 2016-09-21 Unilever PLC, a company registered in England and Wales under company no. 41424 Verbesserungen an verkapselten wirkstoffen
CN103495369B (zh) * 2013-09-30 2016-07-13 常州大学 一种纳米C/Si复合空心球材料及其制备方法
WO2015138638A1 (en) 2014-03-11 2015-09-17 Theraly Pharmaceuticals, Inc. Long acting trail receptor agonists for treatment of autoimmune diseases
KR101558083B1 (ko) * 2014-04-07 2015-10-07 에스케이케미칼주식회사 약물함유 고분자미립구 제조방법
EA038551B1 (ru) 2015-12-17 2021-09-14 Дзе Джонс Хопкинс Юниверсити Способ лечения или профилактики системного склероза
WO2017177148A1 (en) 2016-04-07 2017-10-12 The Johns Hopkins University Compositions and methods for treating pancreatitis and pain with death receptor agonists
CN109843985B (zh) 2016-10-13 2022-06-07 株式会社钟化 聚羟基链烷酸酯的制造方法
IT201700035338A1 (it) * 2017-03-30 2018-09-30 Bio On Spa Composizione cosmetica comprendente un poliestere biodegradabile e una fase oleosa.
CN110129213B (zh) * 2019-05-30 2020-12-01 长春理工大学 一株铜绿假单胞菌及其应用
KR102257252B1 (ko) * 2019-11-07 2021-05-28 한국과학기술연구원 캡슐 제조 방법 및 제조 장치
CN112798693B (zh) * 2019-11-13 2023-11-21 浙江圣兆药物科技股份有限公司 一种在微球制备过程中准确监控plg分子量变化的方法
US11767353B2 (en) 2020-06-05 2023-09-26 Theraly Fibrosis, Inc. Trail compositions with reduced immunogenicity
CN115484926A (zh) * 2020-06-26 2022-12-16 欧莱雅公司 包含可生物降解聚合物的化妆品组合物
FR3131209A1 (fr) * 2021-12-23 2023-06-30 L'oreal Composition cosmétique comprenant un copolymère polyhydroxyalcanoate à chaine hydrocarbonée (in)saturé, et un polymère hydrocarboné
CN114367383B (zh) * 2022-01-13 2024-01-09 苏州丰倍生物科技股份有限公司 一种脂肪酸酯纳米悬浮液、其制备方法和应用
CN115212817A (zh) * 2022-06-29 2022-10-21 珠海麦得发生物科技股份有限公司 一种微球的制备系统及利用其制备pha微球的方法

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2911498A1 (de) 1979-03-23 1980-10-02 Stihl Maschf Andreas Tragbare motorkettensaege
PH19942A (en) 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
US4690682A (en) * 1983-04-15 1987-09-01 Damon Biotech, Inc. Sustained release
JPS60100516A (ja) 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
DE3428372A1 (de) 1984-08-01 1986-02-13 Hoechst Ag, 6230 Frankfurt Mikrokapseln von regulatorischen peptiden mit kontrollierter freisetzung, verfahren zu ihrer herstellung und injektionszubereitungen
JPS6163613A (ja) 1984-09-04 1986-04-01 Mitsui Toatsu Chem Inc 顆粒状に調整された徐放性製剤
JPH0720859B2 (ja) 1985-02-07 1995-03-08 武田薬品工業株式会社 マイクロカプセルの製造法
JPS6457087A (en) 1987-08-27 1989-03-03 Iseki Agricult Mach Cereal-grain drying operation control method
JPH01163135A (ja) 1987-12-18 1989-06-27 Taki Chem Co Ltd 徐放性基剤の製造方法
WO1989008499A1 (en) * 1988-03-17 1989-09-21 Nippon Fine Chemical Co., Ltd. Liposome
JP2827287B2 (ja) 1988-07-05 1998-11-25 武田薬品工業株式会社 水溶性薬物含有徐放型マイクロカプセル
US5064655A (en) * 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method
JP2852080B2 (ja) 1989-09-08 1999-01-27 オリンパス光学工業株式会社 マイクロ波プローブ
JP2653255B2 (ja) 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
JPH057492A (ja) 1990-09-14 1993-01-19 Mitsubishi Gas Chem Co Inc 共重合体の製造法
IS1685B (is) * 1990-12-11 1998-02-24 Bracco International B.V. Aðferð við að búa til fitukúlur (liposomes) sem eru gæddar auknum hæfileika til að draga í sig og halda í sér aðskotaefnum
JP2503315B2 (ja) 1991-03-18 1996-06-05 矢崎総業株式会社 吸収冷凍機
JP2777757B2 (ja) 1991-09-17 1998-07-23 鐘淵化学工業株式会社 共重合体およびその製造方法
CA2078388A1 (en) * 1991-10-02 1993-04-03 Mridula Nair Biocompatible emulsion particles
JPH05294839A (ja) 1992-04-20 1993-11-09 Biomaterial Universe Kk シスプラチン含有生体内分解吸収性高分子の微小球お よびその製造法
JP3277342B2 (ja) 1992-09-02 2002-04-22 武田薬品工業株式会社 徐放性マイクロカプセルの製造法
DK0669128T3 (da) 1992-11-17 2000-06-19 Yoshitomi Pharmaceutical Sustained-release mikrosfære indeholdende antipsykotikum og fremgangsmåde til at fremstille samme
JPH0814967B2 (ja) 1993-02-15 1996-02-14 九州日立マクセル株式会社 ディスククリーナ
EP0646642A3 (de) * 1993-09-30 1995-08-16 Canon Kk Mikroorganismus enthaltender Träger und Methode zur Bodensanierung mittels Verwendung von diesem Träger.
JPH07265065A (ja) 1994-03-29 1995-10-17 Kanegafuchi Chem Ind Co Ltd 共重合体の合成遺伝子による形質転換体および共重合体の製造方法
JPH0819227A (ja) 1994-06-30 1996-01-19 Toshiba Corp コイルブロックの切断方法およびその切断装置
JP3862304B2 (ja) 1994-09-09 2006-12-27 武田薬品工業株式会社 徐放性製剤
JPH08151322A (ja) 1994-09-30 1996-06-11 Takeda Chem Ind Ltd 経口徐放剤
JP3790567B2 (ja) 1994-09-30 2006-06-28 武田薬品工業株式会社 徐放剤
US6333021B1 (en) 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
EP0765660A3 (de) 1995-09-28 1998-09-23 Takeda Chemical Industries, Ltd. Mikrokapseln enthaltend 2-Piperazinon-1-essigsäure Verbindungen
JPH09191893A (ja) 1996-01-22 1997-07-29 Taisei Corp ヒドロキシアルカン酸共重合体の製造方法
JPH11199514A (ja) 1998-01-13 1999-07-27 Meiji Seika Kaisha Ltd 徐放性製剤組成物
US6146665A (en) * 1998-09-09 2000-11-14 Mcgill University Entrapment or microencapsulation of drugs in a polyhydroxyalkanoate formed by enzyme synthesis
EP2305324B1 (de) * 1999-03-25 2014-09-17 Metabolix, Inc. Medizinische Geräte und Anwendungen aus Polyhydroxyalkanoat-Polymeren
EP1120461B1 (de) 1999-08-09 2004-12-08 Japan Science and Technology Agency Verfahren zur herstellung von copolymerisierten polyestern
JP2001069968A (ja) 1999-09-06 2001-03-21 Canon Inc 新規微生物ｏｋ４株およびその微生物を用いたポリヒドロキシアルカノエートの生物的生産方法
JP2001078753A (ja) 1999-09-08 2001-03-27 Canon Inc 新規微生物ｏｋ３株およびその微生物を用いたポリヒドロキシアルカノエートの生物的生産方法
JP2001178484A (ja) 1999-12-27 2001-07-03 Canon Inc ポリヒドロキシアルカン酸の製造方法
US6903053B2 (en) * 2000-06-09 2005-06-07 The Procter & Gamble Company Agricultural items and agricultural methods comprising biodegradable copolymers
US7153622B2 (en) * 2001-04-27 2006-12-26 Canon Kabushiki Kaisha Electrostatic charge image developing toner, producing method therefor, image forming method and image forming apparatus utilizing the toner, construct and method for making the construct
JP3625433B2 (ja) 2001-04-27 2005-03-02 キヤノン株式会社 粒状構造体及びその製造方法
JP3684175B2 (ja) 2001-04-27 2005-08-17 キヤノン株式会社 構造体及びその製造方法
JP3990880B2 (ja) * 2001-07-10 2007-10-17 キヤノン株式会社 ポリヒドロキシアルカノエート被覆リポソームの製造方法

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EP1275378A2 (de) 2003-01-15
KR100521526B1 (ko) 2005-10-13
EP1275378B1 (de) 2009-04-15
US20030194443A1 (en) 2003-10-16
US7615233B2 (en) 2009-11-10
KR20030007089A (ko) 2003-01-23
EP1275378A3 (de) 2003-10-15
CN1278675C (zh) 2006-10-11

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