DE3856544T2 - Verfahren zur Lagerung labiler Proteine - Google Patents

Verfahren zur Lagerung labiler Proteine

Info

Publication number
DE3856544T2
DE3856544T2 DE3856544T DE3856544T DE3856544T2 DE 3856544 T2 DE3856544 T2 DE 3856544T2 DE 3856544 T DE3856544 T DE 3856544T DE 3856544 T DE3856544 T DE 3856544T DE 3856544 T2 DE3856544 T2 DE 3856544T2
Authority
DE
Germany
Prior art keywords
proteins
meta
protein
soluble protein
aqueous medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3856544T
Other languages
German (de)
English (en)
Other versions
DE3856544D1 (de
Inventor
Shanfun Ching
Patricia A Billing
Julian Gordon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22107719&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3856544(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE3856544D1 publication Critical patent/DE3856544D1/de
Publication of DE3856544T2 publication Critical patent/DE3856544T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90Plate chromatography, e.g. thin layer or paper chromatography
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/967Standards, controls, materials, e.g. validation studies, buffer systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/97Test strip or test slide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/801Electron dense compounds, e.g. ferritin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/826Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Colloid Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE3856544T 1987-07-13 1988-07-12 Verfahren zur Lagerung labiler Proteine Expired - Lifetime DE3856544T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/072,459 US5120643A (en) 1987-07-13 1987-07-13 Process for immunochromatography with colloidal particles

Publications (2)

Publication Number Publication Date
DE3856544D1 DE3856544D1 (de) 2002-12-12
DE3856544T2 true DE3856544T2 (de) 2003-08-21

Family

ID=22107719

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3854951T Expired - Lifetime DE3854951T3 (de) 1987-07-13 1988-07-12 Verfahren für Immunochromatographie mit Kolloidteilchen
DE3856544T Expired - Lifetime DE3856544T2 (de) 1987-07-13 1988-07-12 Verfahren zur Lagerung labiler Proteine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3854951T Expired - Lifetime DE3854951T3 (de) 1987-07-13 1988-07-12 Verfahren für Immunochromatographie mit Kolloidteilchen

Country Status (8)

Country Link
US (3) US5120643A (es)
EP (2) EP0675361B1 (es)
JP (1) JPH0760159B2 (es)
AT (2) ATE227427T1 (es)
AU (1) AU614294B2 (es)
CA (1) CA1306675C (es)
DE (2) DE3854951T3 (es)
ES (2) ES2085257T5 (es)

Families Citing this family (407)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
DE3445816C1 (de) 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US5514602A (en) * 1986-06-09 1996-05-07 Ortho Diagnostic Systems, Inc. Method of producing a metal sol reagent containing colloidal metal particles
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
USRE38430E1 (en) 1987-03-27 2004-02-17 Becton, Dickinson And Company Solid phase chromatographic immunoassay
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification
JPH0746107B2 (ja) 1987-04-27 1995-05-17 ユニリーバー・ナームローゼ・ベンノートシヤープ 検定法
DE3715485A1 (de) * 1987-05-09 1988-11-17 Boehringer Mannheim Gmbh Stabilisierung von ss-galactosidase
US4954452A (en) * 1987-07-09 1990-09-04 Abbott Laboratories Non-metal colloidal particle immunoassay
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
ES2039025T3 (es) * 1987-11-16 1993-08-16 Janssen Pharmaceutica N.V. Un agregado para determinar sustancias combinables.
US5670381A (en) * 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
US5866322A (en) * 1988-01-29 1999-02-02 Abbott Laboratories Method for performing Rubella assay
US5459078A (en) * 1988-01-29 1995-10-17 Abbott Laboratories Methods and reagents for performing ion-capture digoxin assays
US5459080A (en) * 1988-01-29 1995-10-17 Abbott Laboratories Ion-capture assays using a specific binding member conjugated to carboxymethylamylose
AU2684488A (en) * 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
IT1227293B (it) * 1988-10-06 1991-04-05 Boehringer Biochemia Srl Dispositivo e metodo per la diagnosi di gravidanza
US5348891A (en) * 1988-11-15 1994-09-20 H.B.T. Holland Biotechnology Method for an increased visualization of the reaction product of a specifically binding substance and a corresponding bindable substance and test kit therefor
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US6352862B1 (en) * 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5411858A (en) * 1989-05-17 1995-05-02 Actimed Laboratories, Inc. Manufacturing process for sample initiated assay device
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
WO1991013998A1 (en) * 1990-03-12 1991-09-19 Biosite Diagnostics, Inc. Bioassay device with non-absorbent textured capillary surface
US5922615A (en) 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
EP0462376B1 (en) * 1990-05-09 1996-07-24 Abbott Laboratories Conjugate recovery binding assays
DE4024544A1 (de) * 1990-08-02 1992-02-06 Boehringer Mannheim Gmbh Analyseelement und verfahren zu seiner herstellung
US5266497A (en) * 1990-08-31 1993-11-30 Japan Synthetic Rubber Co., Ltd. Immunochromatographic assay with improved colored latex
DE69126142T2 (de) * 1990-09-26 1997-09-11 Akers Lab Inc Verbessertes bestimmungsverfahren für liganden
JP2868900B2 (ja) * 1991-01-11 1999-03-10 クイデル コーポレイション ワンステップ側方流非吸収性アッセイ
JP3108115B2 (ja) * 1991-03-28 2000-11-13 ロート製薬株式会社 イムノクロマトグラフ法による物質検出法
US5607863A (en) 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5869345A (en) 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5468648A (en) 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
ES2112906T3 (es) * 1991-05-30 1998-04-16 Abbott Lab Dispositivos que permiten realizar analisis de fijacion con captura de iones.
EP0588958A1 (en) * 1991-06-13 1994-03-30 Pacific Biotech Inc. Assay for the detection of specific ligands
US5686315A (en) * 1991-06-14 1997-11-11 Quidel Corporation Assay device for one step detection of analyte
JPH0545361A (ja) * 1991-06-27 1993-02-23 Idemitsu Petrochem Co Ltd 液体試料の分析方法及び該方法に用いる液体試料分析用基板
DE69322781T2 (de) * 1992-01-22 1999-08-26 Actimed Lab Herstellungsverfahren für eine durch die probe initiierte assayvorrichtung
DE4202850A1 (de) * 1992-01-31 1993-08-05 Boehringer Mannheim Gmbh Analysenelement fuer immunoassays
ES2151902T3 (es) * 1992-03-10 2001-01-16 Quidel Corp Medio de separacion de globulos rojos para dosificarlos mediante union especifica.
US5310647A (en) * 1992-04-01 1994-05-10 Cherrystone Corporation Detection and measurement of destructive and polymer forming enzymes by colloidal flocculation
US6664114B1 (en) * 1992-08-03 2003-12-16 Sapidyne Instruments, Inc. Solid phase assay for detection of ligands
US5372783A (en) * 1992-08-03 1994-12-13 Sapidyne, Inc. Assay system
US5356782A (en) * 1992-09-03 1994-10-18 Boehringer Mannheim Corporation Analytical test apparatus with on board negative and positive control
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
US5807752A (en) * 1992-09-11 1998-09-15 Boehringer Mannheim Corporation Assay using an unblocked solid phase with immobilized analyte binding partner
US5736410A (en) * 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
AU6357394A (en) * 1993-03-04 1994-09-26 Sapidyne, Inc. Assay flow apparatus and method
US5500375A (en) * 1993-04-13 1996-03-19 Serex, Inc. Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats
JP3479100B2 (ja) 1993-06-02 2003-12-15 帝国臓器製薬株式会社 免疫化学的簡易半定量方法および装置
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
DE4331596A1 (de) * 1993-09-17 1995-03-23 Boehringer Mannheim Gmbh Verfahren zur quantitativen Analyse von Probenflüssigkeiten
US5770389A (en) * 1993-09-27 1998-06-23 Abbott Laboratories Apparatus and method for determining the quanity of an analyte in a biological sample by means of transmission photometry
JP3755826B2 (ja) * 1993-12-09 2006-03-15 触媒化成工業株式会社 アルミナの製造方法と装置
WO1995021190A1 (en) * 1994-02-07 1995-08-10 The United States Of America, Represented By The Secretary Of Agriculture Detection of wheat that has experienced elevated temperatures during the grain filling period
ATE196689T1 (de) * 1994-03-30 2000-10-15 Johnson & Johnson Clin Diag Verringerung der störung in chemilumineszierenden dünnschicht-immuntests
US5597700A (en) * 1994-04-28 1997-01-28 California Research, Llc Method for detecting free insulin-like growth-factor-binding protein 1 and a test device for detecting the ruptures of fetal membranes using the above method
US5658747A (en) * 1994-05-10 1997-08-19 Biocontrol System, Inc. Compositions and methods for control of reactivity between diagnostic reagents and microorganisms
WO1995032414A1 (en) * 1994-05-20 1995-11-30 Chemtrak, Inc. Qualitative surface immunoassay using consecutive reagent application
US6653066B1 (en) 1994-06-17 2003-11-25 Trinity Biotech Device and method for detecting polyvalent substances
EP0699906B1 (de) 1994-07-25 2002-04-24 Roche Diagnostics GmbH Verfahren zum Nachweis der Kontamination einer Oberfläche mit einem Analyten
US6818199B1 (en) * 1994-07-29 2004-11-16 James F. Hainfeld Media and methods for enhanced medical imaging
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US5521102A (en) * 1994-08-08 1996-05-28 Quidel Corporation Controlled sensitivity immunochromatographic assay
DE4443386C2 (de) * 1994-12-06 1996-09-19 Seratec Ges Fuer Biotechnologi Vorrichtung zur Durchführung eines Schwangerschaftstests
SE9500184D0 (sv) * 1995-01-20 1995-01-20 Pharmacia Ab Analysmetod som utnyttjar biospecifika affinitetsreaktioner och märkt reaktant samt reagens att användas i föredragen utförandeform
US5569608A (en) * 1995-01-30 1996-10-29 Bayer Corporation Quantitative detection of analytes on immunochromatographic strips
AU4996796A (en) * 1995-02-28 1996-09-18 Joel R.L. Ehrenkranz Rapid, self-performing tsh immunoassay
US6309671B1 (en) 1995-04-14 2001-10-30 Inhale Therapeutic Systems Stable glassy state powder formulations
US5804452A (en) * 1995-04-27 1998-09-08 Quidel Corporation One step urine creatinine assays
US6319676B1 (en) 1995-05-02 2001-11-20 Carter Wallace, Inc. Diagnostic detection device and method
US5739041A (en) * 1995-05-02 1998-04-14 Carter Wallace, Inc. Diagnostic detection device
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
DE69617568T2 (de) * 1995-09-08 2002-08-01 Fujirebio Kk Immunoassay Vorrichtung und Testverfahren zu seiner Verwendung
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
WO1997034150A1 (en) * 1996-03-14 1997-09-18 Abbott Laboratories Binding members extending from particles for immunoassay
US5876944A (en) * 1996-06-10 1999-03-02 Bayer Corporation Method for amplification of the response signal in a sandwich immunoassay
US5871905A (en) * 1996-09-04 1999-02-16 Epitope, Inc. Reduction of false positives in oral-fluid based immunoassays
US6001658A (en) * 1996-09-13 1999-12-14 Diagnostic Chemicals Limited Test strip apparatus and method for determining presence of analyte in a fluid sample
US6979576B1 (en) * 1997-07-25 2005-12-27 Shu-Ching Cheng Methods of use of one step immunochromatographic device for Streptococcus A antigen
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US20050101032A1 (en) * 1997-02-10 2005-05-12 Metrika, Inc. Assay device, composition, and method of optimizing assay sensitivity
CA2285384C (en) * 1997-03-28 2012-10-16 Epitope, Inc. Simultaneous collection of dna and non-nucleic analytes from oral fluids
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6258548B1 (en) 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
IT1292163B1 (it) * 1997-06-13 1999-01-25 Giorgio Torelli Dispositivo immunocromatografico a fissazione dell'analita
US5895765A (en) * 1997-06-30 1999-04-20 Bayer Corporation Method for the detection of an analyte by immunochromatography
US5985675A (en) 1997-12-31 1999-11-16 Charm Sciences, Inc. Test device for detection of an analyte
US6037186A (en) * 1997-07-16 2000-03-14 Stimpson; Don Parallel production of high density arrays
US6319466B1 (en) 1997-07-16 2001-11-20 Charm Sciences, Inc. Test device for detecting the presence of a residue analyte in a sample
EP1473565B1 (en) * 1997-07-16 2010-08-25 Charm Sciences Inc. A test device and method for detecting the presence of a residue analyte in a sample
US6833275B1 (en) * 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
US5922533A (en) * 1997-08-15 1999-07-13 Abbott Laboratories Rapid assay for simultaneous detection and differentiation of antibodies to HIV groups
US6824985B1 (en) * 1997-09-09 2004-11-30 Bayer Corporation Formulation for reducing urea effect for immunochromatography assays using urine samples
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
US6004525A (en) * 1997-10-06 1999-12-21 Kabushiki Kaisha Toyota Chuo Kenkyusho Hollow oxide particle and process for producing the same
US6423299B1 (en) 1997-10-31 2002-07-23 Vincent Fischetti Composition for treatment of a bacterial infection of an upper respiratory tract
US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US7232576B2 (en) 1997-10-31 2007-06-19 New Horizons Diagnostics Corp Throat lozenge for the treatment of Streptococcus Group A
US6752988B1 (en) 2000-04-28 2004-06-22 New Horizons Diagnostic Corp Method of treating upper resiratory illnesses
US6277399B1 (en) 1997-10-31 2001-08-21 New Horizon Diagnostics Corporation Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
US20030129146A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti The use of bacterial phage associated lysing proteins for treating bacterial dental caries
US20020136712A1 (en) * 1997-10-31 2002-09-26 Fischetti Vincent Bacterial phage associated lysing enzymes for the prophylactic and therapeutic treatment of colonization and infections caused by streptococcus pneumoniae
US6406692B1 (en) * 1997-10-31 2002-06-18 New Horizons Diagnostics Corp Composition for treatment of an ocular bacterial infection
US20030129147A1 (en) * 1997-10-31 2003-07-10 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6428784B1 (en) 1997-10-31 2002-08-06 New Horizons Diagnostics Corp Vaginal suppository for treating group B Streptococcus infection
US20030082110A1 (en) * 1997-10-31 2003-05-01 Vincent Fischetti Use of bacterial phage associated lysing proteins for treating bacterial dental caries
US6432444B1 (en) 1997-10-31 2002-08-13 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymes for treating dermatological infections
SE9704933D0 (sv) 1997-12-30 1997-12-30 Pharmacia & Upjohn Diag Ab Metod som utnyttjar en ny kalibrator och test kit som innehåller kalibratorn
SE9704935D0 (sv) 1997-12-30 1997-12-30 Pharmacia & Upjohn Diag Ab Analysmetod med partiklar
US6673629B2 (en) 1998-01-15 2004-01-06 Abbott Laboratories Neutralization of polycations in a chromatographic device for whole blood use
US6267722B1 (en) 1998-02-03 2001-07-31 Adeza Biomedical Corporation Point of care diagnostic systems
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
US6303081B1 (en) 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
AU3219099A (en) * 1998-03-30 1999-10-18 Epitope, Inc. Collection device for single step assay of oral fluids
US6368873B1 (en) * 1998-04-09 2002-04-09 Applied Biotech, Inc. Identification of human urine for drug testing
US7220596B2 (en) * 1998-04-15 2007-05-22 Utah State University Real time detection of antigens
USD432244S (en) * 1998-04-20 2000-10-17 Adeza Biomedical Corporation Device for encasing an assay test strip
USD434153S (en) * 1998-04-20 2000-11-21 Adeza Biomedical Corporation Point of care analyte detector system
SE9801563D0 (sv) 1998-04-30 1998-04-30 Pharmacia & Upjohn Diag Ab Förfarande med separation och kit att användas vid förfarandet
US20060019404A1 (en) * 1998-05-06 2006-01-26 Blatt Joel M Quantitative assay with extended dynamic range
EP1086375A4 (en) * 1998-06-12 2004-12-15 New Horizons Diagnostics Inc COLLOIDAL COLORIMETRIC TESTS IN CONTINUOUS FLOW AND SIDE FLOW USING SOLUBLE SUBMICRONIC PARTICLES
US7347972B1 (en) * 1998-07-22 2008-03-25 Jin Po Lee Multiple analyte assay device
US6410341B1 (en) 1998-08-06 2002-06-25 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
WO2000008466A2 (en) 1998-08-06 2000-02-17 Spectral Diagnostics, Inc. Analytical test device and method
US6171870B1 (en) 1998-08-06 2001-01-09 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
US6214629B1 (en) 1998-08-06 2001-04-10 Spectral Diagnostics, Inc. Analytical test device and method for use in medical diagnoses
CN1214816C (zh) * 1998-09-18 2005-08-17 比南股份有限公司 使用纯化的抗原特异性抗体快速检测肺炎链球菌的体外方法和材料
GB9823397D0 (en) * 1998-10-27 1998-12-23 Rsr Ltd Assays for thyroid autoantibodies
US6136610A (en) 1998-11-23 2000-10-24 Praxsys Biosystems, Inc. Method and apparatus for performing a lateral flow assay
US6566051B1 (en) * 1999-01-15 2003-05-20 Medtox Scientific, Inc. Lateral flow test strip
US6262265B1 (en) 1999-06-18 2001-07-17 Microgenics Corporation Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay
JP4212189B2 (ja) * 1999-07-12 2009-01-21 富士フイルム株式会社 乾式分析方法及び乾式分析要素
US6699507B1 (en) 1999-08-05 2004-03-02 Wisconsin Alulmni Research Foundation Colloidal particles of different element composition for specific labeling purposes
US20020127215A1 (en) * 1999-09-14 2002-09-12 Lawrence Loomis Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections
US7063837B2 (en) * 1999-09-14 2006-06-20 New Horizons Diagnostics Corp Syrup composition containing phage associated lytic enzymes
US6306665B1 (en) 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
US20020004246A1 (en) * 2000-02-07 2002-01-10 Daniels Robert H. Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
US6365417B1 (en) 2000-02-09 2002-04-02 A-Fem Medical Corporation Collection device for lateral flow chromatography
US6998273B1 (en) 2000-02-09 2006-02-14 A-Fem Medical Corporation Collection device for lateral flow chromatography
WO2001066568A2 (en) * 2000-03-09 2001-09-13 Heska Corporation Use of recombinant antigens to determine the immune status of an animal
US6607922B2 (en) 2000-03-17 2003-08-19 Quantum Design, Inc. Immunochromatographic assay method and apparatus
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
US6656745B1 (en) 2000-06-02 2003-12-02 Francis X. Cole Devices and methods for a multi-level, semi-quantitative immunodiffusion assay
CU22968A1 (es) * 2000-06-07 2004-07-14 Ct Ingenieria Genetica Biotech Procedimiento para la detección de anticuerpos anti transglutaminasa con utilidad en el diagnóstico de la enfermedad celíaca
ATE349011T1 (de) 2000-10-03 2007-01-15 Minerva Biotechnologies Corp Magnetisches in situ dilutionsverfahren
US6764825B1 (en) * 2000-10-13 2004-07-20 Tang J. Wang Methods and device for detecting prostate specific antigen (PSA)
EP1333854A4 (en) * 2000-11-02 2005-10-05 New Horizons Diagnostics Corp USE OF BACTERIAL PHAGS IN CONNECTION WITH LYSEENZYMS FOR PREVENTING FOOD DRUGS
US7867756B2 (en) 2001-04-12 2011-01-11 Arkray, Inc. Specimen analyzing implement
WO2002100444A1 (en) * 2001-06-08 2002-12-19 Biosphere Medical Inc. Colloidal metal labelled microparticles, their production and use
US20040213765A1 (en) * 2001-07-13 2004-10-28 Vincent Fischetti Use of bacterial phage associated lytic enzymes to prevent food poisoning
US7790439B2 (en) 2001-08-09 2010-09-07 Panasonic Corporation Biosensor and measurement method
US20030059951A1 (en) * 2001-08-14 2003-03-27 Frushour Susan L.M. Maternal status testing in animals
US8481334B1 (en) 2001-11-06 2013-07-09 Charm Sciences, Inc. Method of attaching a ligand to a solid support
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US6703216B2 (en) 2002-03-14 2004-03-09 The Regents Of The University Of California Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB)
US20040018576A1 (en) * 2002-07-24 2004-01-29 Dematteo Todd M. Bence Jones protein testing cassette
SI1535068T1 (sl) 2002-08-13 2010-07-30 N Dia Inc Naprave in postopki za odkrivanje amnijske tekočine v vaginalnih izločkih
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US20040092036A1 (en) * 2002-09-11 2004-05-13 Lattec I/S Device for analysing analyte compounds and use hereof
ES2525318T3 (es) * 2002-10-11 2014-12-22 Zbx Corporation Dispositivos de diagnóstico
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7597936B2 (en) * 2002-11-26 2009-10-06 University Of Utah Research Foundation Method of producing a pigmented composite microporous material
EP1576351A4 (en) * 2002-11-26 2010-06-23 Univ Utah Res Found MICROPOROUS MATERIALS, METHODS, AND ARTICLES FOR LOCATING AND QUANTIFYING ANALYTES
US20040121334A1 (en) * 2002-12-19 2004-06-24 Kimberly-Clark Worldwide, Inc. Self-calibrated flow-through assay devices
US7197169B2 (en) * 2003-01-02 2007-03-27 Kuo-Jeng Wang Method for detecting a response of each probe zone on a test strip
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
GB0301225D0 (en) * 2003-01-20 2003-02-19 Univ Sunderland Surface layer immuno-chromatography
FI118904B (fi) * 2003-03-28 2008-04-30 Ani Biotech Oy Monikanavainen testiväline, menetelmä sen valmistamiseksi ja sen käyttö
GB0312403D0 (en) * 2003-05-29 2003-07-02 Axis Shield Asa Assay
EP1664772A4 (en) * 2003-08-04 2007-01-03 Univ Emory POROUS MATERIALS ENCLOSED WITH NANO-SPECIES
EP2031390B1 (en) * 2003-08-20 2014-07-16 Seikagaku Corporation Stabilizing agent and blocking agent
US7722817B2 (en) * 2003-08-28 2010-05-25 Epocal Inc. Lateral flow diagnostic devices with instrument controlled fluidics
US7238538B2 (en) * 2003-09-19 2007-07-03 Freitag Helmut E Chromatographic assay device and methods
EP1664781B1 (en) 2003-09-22 2013-05-08 Quidel Corporation Devices for the detection of multiple analytes in a sample
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7410808B1 (en) 2003-12-08 2008-08-12 Charm Sciences, Inc. Method and assay for detection of residues
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20080227220A1 (en) * 2004-01-29 2008-09-18 Maartje-Maria Franse Lateral Flow Binding Assay
DE602005016527D1 (de) * 2004-02-09 2009-10-22 Rapid Pathogen Screening Inc Verfahren zur schnelldiagnose von zielen in menschlichen körperflüssigkeiten
US20050255533A1 (en) * 2004-02-10 2005-11-17 Brendan Bioscience, Llc Comprehensive food allergy test
FI20040205A (fi) * 2004-02-11 2005-08-12 Reagena Ltd Oy Menetelmä ja laite pikatestin valmistamiseksi
US20050191704A1 (en) * 2004-03-01 2005-09-01 Kimberly-Clark Worldwide, Inc. Assay devices utilizing chemichromic dyes
WO2005095967A1 (en) 2004-03-23 2005-10-13 Quidel Corporation Hybrid phase lateral flow assay
CN100357738C (zh) * 2004-03-26 2007-12-26 博奥生物有限公司 一种检测小分子化合物的方法
US7319032B2 (en) * 2004-04-22 2008-01-15 Medtox Non-sugar sweeteners for use in test devices
US20060024757A1 (en) * 2004-07-30 2006-02-02 Robert Hussa Detection of oncofetal fibronectin for selection of concepti
US20060040258A1 (en) * 2004-08-23 2006-02-23 Huiyan Guo Water-soluble conjugates and methods of preparation
US20060046310A1 (en) * 2004-08-25 2006-03-02 Zong-Li Xia Amplification method for solid phase immunoassays
JP2008512687A (ja) * 2004-09-10 2008-04-24 アラン ディー. プロノヴォスト 唾液グルコースのモニタリング方法
US7465587B2 (en) 2004-12-03 2008-12-16 Genzyme Corporation Diagnostic assay device
US20060154260A1 (en) * 2005-01-07 2006-07-13 Barbour William M Sample preparation methods for diagnostic analyses
EP1843850B1 (en) 2005-01-31 2015-11-18 Realbio Technologies Ltd. Multistep reaction lateral flow capillary device
US8445293B2 (en) * 2005-02-09 2013-05-21 Rapid Pathogen Screening, Inc. Method to increase specificity and/or accuracy of lateral flow immunoassays
US8614101B2 (en) * 2008-05-20 2013-12-24 Rapid Pathogen Screening, Inc. In situ lysis of cells in lateral flow immunoassays
US8669052B2 (en) 2008-06-10 2014-03-11 Rapid Pathogen Screening, Inc. Lateral flow nucleic acid detector
EP1848999A4 (en) * 2005-02-16 2012-05-30 Gao Ping Epitope Diagnostics FECAL SAMPLE TESTING DEVICE AND METHODS OF USE THEREOF
US20060205090A1 (en) * 2005-03-14 2006-09-14 Newton Michael W Water-soluble conjugates for electrochemical detection
EP1869468B1 (en) * 2005-03-29 2010-05-05 Inverness Medical Switzerland GmbH Colloidal metal conjugates
US7939342B2 (en) 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
DK3264094T3 (da) 2005-04-04 2020-11-23 Biogen Ma Inc Fremgangsmåder til evaluering af en immunrespons på et terapeutisk middel
US7439079B2 (en) 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US7858384B2 (en) * 2005-04-29 2010-12-28 Kimberly-Clark Worldwide, Inc. Flow control technique for assay devices
US7803319B2 (en) * 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US20060263907A1 (en) * 2005-04-29 2006-11-23 Zweig Stephen E Fluorescence lateral flow immunoassay
US20070042427A1 (en) * 2005-05-03 2007-02-22 Micronics, Inc. Microfluidic laminar flow detection strip
ATE515703T1 (de) * 2005-05-23 2011-07-15 Phadia Ab Verfahren und vorrichtungen für lateralfluss- tests mit zwei schritten
US7785865B2 (en) 2005-06-28 2010-08-31 Zbx Corporation Membrane array and analytical device
US20070015166A1 (en) * 2005-07-14 2007-01-18 Nilsen Thor W Lateral flow methods and devices for detection of nucleic acid binding proteins
US8003399B2 (en) * 2005-08-31 2011-08-23 Kimberly-Clark Worldwide, Inc. Nitrite detection technique
US7504235B2 (en) * 2005-08-31 2009-03-17 Kimberly-Clark Worldwide, Inc. Enzyme detection technique
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
US7344893B2 (en) * 2005-10-13 2008-03-18 Auric Enterprises, Llc Immuno-gold lateral flow assay
US7910381B2 (en) * 2005-10-13 2011-03-22 BioAssay Works Immuno gold lateral flow assay
US8153444B2 (en) * 2005-10-13 2012-04-10 Auric Enterprises, Llc Immuno gold lateral flow assay
JP2007139649A (ja) * 2005-11-21 2007-06-07 Asahi Kasei Corp 分析装置の多孔体
US7279136B2 (en) * 2005-12-13 2007-10-09 Takeuchi James M Metering technique for lateral flow assay devices
US7618810B2 (en) * 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US7871568B2 (en) * 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) * 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
US20070202561A1 (en) * 2006-02-10 2007-08-30 Becton Dickinson And Company Electronic Detection Immunoassays that Utilize a Binder Support Medium
CA2659773A1 (en) * 2006-02-21 2007-08-30 Nanogen, Inc. Methods and compositions for analyte detection
JP2009528359A (ja) 2006-02-28 2009-08-06 エラン ファーマシューティカルズ,インコーポレイテッド ナタリズマブを用いて炎症性疾患および自己免疫性疾患を治療する方法
SG170058A1 (en) 2006-03-03 2011-04-29 Elan Pharm Inc Methods of treating inflammatory and autoimmune diseases with natalizumab
EP2007905B1 (en) * 2006-03-15 2012-08-22 Micronics, Inc. Integrated nucleic acid assays
US7547557B2 (en) * 2006-06-13 2009-06-16 Quantum Design, Inc. Directed-flow assay device
US20080014657A1 (en) * 2006-07-12 2008-01-17 Beckton Dickinson And Company Use of Albumin, Bovine, P-Aminophenyl N-Acetyl B-D Glucosaminide as a Control Line for an Immunoassay Device
ATE498615T1 (de) 2006-07-14 2011-03-15 Chemocentryx Inc Triazolylphenylbenzensulfonamide
WO2008021954A2 (en) * 2006-08-09 2008-02-21 Biogen Idec Ma Inc. Method for distribution of a drug
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
WO2008037026A1 (en) 2006-09-28 2008-04-03 The Macfarlane Burnet Institute For Medical Research And Public Health Limited A method of diagnosis and kit therefor
US7749775B2 (en) 2006-10-03 2010-07-06 Jonathan Scott Maher Immunoassay test device and method of use
JP2008139297A (ja) * 2006-11-08 2008-06-19 Fujifilm Corp イムノクロマトグラフキット
US20080138842A1 (en) * 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
US8012761B2 (en) * 2006-12-14 2011-09-06 Kimberly-Clark Worldwide, Inc. Detection of formaldehyde in urine samples
US8377379B2 (en) * 2006-12-15 2013-02-19 Kimberly-Clark Worldwide, Inc. Lateral flow assay device
US7935538B2 (en) * 2006-12-15 2011-05-03 Kimberly-Clark Worldwide, Inc. Indicator immobilization on assay devices
US7846383B2 (en) * 2006-12-15 2010-12-07 Kimberly-Clark Worldwide, Inc. Lateral flow assay device and absorbent article containing same
US9086408B2 (en) 2007-04-30 2015-07-21 Nexus Dx, Inc. Multianalyte assay
WO2009005552A2 (en) * 2007-03-29 2009-01-08 Epitype Corporation Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
EP2716656B1 (en) 2007-06-15 2016-10-12 Xiamen University Monoclonal antibodies binding to avian influenza virus subtype H5 haemagglutinin and uses thereof
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
KR101849560B1 (ko) * 2007-07-12 2018-04-17 케모센트릭스, 인크. 염증의 치료를 위한 ccr2 조절물질로서 융합된 헤테로아릴 피리딜과 페닐 벤젠술폰아마이드
US20090208975A1 (en) * 2007-12-13 2009-08-20 Beckman Coulter, Inc. Device and methods for detecting a target cell
US9797898B2 (en) 2008-05-20 2017-10-24 Rapid Pathogen Screening, Inc. Methods and devices for using mucolytic agents including N-acetyl cysteine (NAC)
US9068981B2 (en) 2009-12-04 2015-06-30 Rapid Pathogen Screening, Inc. Lateral flow assays with time delayed components
US8815609B2 (en) 2008-05-20 2014-08-26 Rapid Pathogen Screening, Inc. Multiplanar lateral flow assay with diverting zone
US8609433B2 (en) * 2009-12-04 2013-12-17 Rapid Pathogen Screening, Inc. Multiplanar lateral flow assay with sample compressor
US20130196310A1 (en) 2008-05-20 2013-08-01 Rapid Pathogen Screening, Inc. Method and Device for Combined Detection of Viral and Bacterial Infections
US8962260B2 (en) 2008-05-20 2015-02-24 Rapid Pathogen Screening, Inc. Method and device for combined detection of viral and bacterial infections
US20110086359A1 (en) 2008-06-10 2011-04-14 Rapid Pathogen Screening, Inc. Lateral flow assays
CN102076415B (zh) 2008-06-29 2015-06-24 瑞尔比奥技术有限公司 尤其可用作生物测定过程中的捕捉装置的液体转移装置
WO2010011860A1 (en) * 2008-07-23 2010-01-28 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
US9234889B1 (en) 2008-12-18 2016-01-12 Charm Sciences, Inc. Method and test strip for detecting residues
DK2391892T3 (en) 2009-01-30 2017-04-24 Mycartis N V BIOMARKET FOR DIAGNOSIS, PREDICTION AND / OR PROJECTS OF ACUTE HEART FAILURE AND USE thereof
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
WO2010132447A2 (en) 2009-05-11 2010-11-18 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
US20100290948A1 (en) * 2009-05-15 2010-11-18 Xuedong Song Absorbent articles capable of indicating the presence of urinary tract infections
JP5414424B2 (ja) * 2009-08-31 2014-02-12 シスメックス株式会社 目的物質の検出方法、及び目的物質を検出するためのクロマトグラフィー用試験キット
AU2010303156B2 (en) 2009-10-11 2016-02-04 Biogen Ma Inc. Anti-VLA-4 related assays
US20120220493A1 (en) 2009-10-21 2012-08-30 Pronota N.V. Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
KR101464418B1 (ko) 2009-11-17 2014-11-21 아사히 가세이 셍이 가부시키가이샤 유기 착색 미립자, 이것을 포함하는 진단약 키트 및 인비트로 진단 방법
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
HUE060312T2 (hu) 2010-01-11 2023-02-28 Biogen Ma Inc A JC vírus antitestek vizsgálata
US9132423B2 (en) 2010-01-29 2015-09-15 Micronics, Inc. Sample-to-answer microfluidic cartridge
WO2011119484A1 (en) 2010-03-23 2011-09-29 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
AU2011231537B2 (en) 2010-03-26 2016-05-12 Mycartis Nv LTBP2 as a biomarker for renal dysfunction, glomerular filtration rate, dyspnea, acute heart failure, left ventricular hypertrophy, cardiac fibrosis, preeclampsia, pregnancy-associated proteinuria
DK2556090T3 (en) 2010-04-09 2016-05-30 Critical Care Diagnostics Inc Soluble, human st-2 antibodies and assays
US20130045889A1 (en) 2010-04-13 2013-02-21 Pronota N.V. Biomarkers for hypertensive disorders of pregnancy
EP2566949B1 (en) 2010-05-06 2023-02-15 Charm Sciences, Inc. Reader-incubator apparatus
EP2576806B1 (en) 2010-05-26 2017-03-08 The Board of Trustees of the University of Illionis Personal glucose meters for detection and quantification of a broad range of analytes
CA2802305A1 (en) 2010-07-08 2012-01-12 Pronota N.V. Biomarker for hypertensive disorders of pregnancy
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US8828329B2 (en) 2010-10-01 2014-09-09 Church & Dwight, Co., Inc. Electronic analyte assaying device
AU2011340630B2 (en) 2010-12-06 2017-01-19 Mycartis Nv Biomarkers and parameters for hypertensive disorders of pregnancy
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
CN103582816B (zh) 2011-04-06 2017-04-19 奥索临床诊断有限公司 具有斜方形突出的测定装置
EP2771349B1 (en) 2011-09-16 2020-02-26 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
SG11201400677PA (en) 2011-09-16 2014-06-27 Credo Biomedical Pte Ltd Molecular diagnostic assay device and method of use
US20130116597A1 (en) * 2011-11-04 2013-05-09 Phenomenex, Inc. Method and apparatus for acquiring blood for testing
WO2013083781A2 (en) 2011-12-08 2013-06-13 Pronota N.V. Biomarkers and test panels useful in systemic inflammatory conditions
CN104136924B (zh) 2011-12-15 2018-05-29 麦卡蒂斯股份有限公司 用于先兆子痫的生物标志物和参数
WO2013095729A1 (en) 2011-12-22 2013-06-27 Life Technologies Corporation Sequential lateral flow capillary device for analyte determination
US20130171619A1 (en) 2011-12-30 2013-07-04 General Electric Company Porous membranes having a hydrophilic coating and methods for their preparation and use
CA2802670C (en) 2012-01-20 2020-09-01 Ortho-Clinical Diagnostics, Inc. Assay device having multiple reagent cells
CN103212455B (zh) 2012-01-20 2016-12-28 奥索临床诊断有限公司 在角附近具有均匀流的测定装置
CA2802260C (en) 2012-01-20 2021-03-30 Ortho-Clinical Diagnostics, Inc. Controlling fluid flow through an assay device
KR20130085992A (ko) 2012-01-20 2013-07-30 오르토-클리니칼 다이아그노스틱스, 인코포레이티드 제어가능한 샘플 크기를 갖는 분석 장치
WO2013109821A1 (en) 2012-01-20 2013-07-25 Ortho-Clinical Diagnostics, Inc. Assay device having multiplexing
EP3418397B1 (en) 2012-01-24 2020-10-07 CD Diagnostics, Inc. System for detecting infection in synovial fluid
CN107505465B (zh) 2012-01-31 2020-01-14 明尼苏达大学董事会 热对比测定和读取器
US10725033B2 (en) 2012-01-31 2020-07-28 Regents Of The University Of Minnesota Lateral flow assays with thermal contrast readers
US10816492B2 (en) 2012-01-31 2020-10-27 Regents Of The University Of Minnesota Lateral flow assays with thermal contrast readers
EP3415919B1 (en) 2012-02-07 2020-07-29 Intuitive Biosciences Inc. Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
SG10201700493XA (en) 2012-02-29 2017-03-30 Chemocentryx Inc Pyrazol-1-yl benzene sulfonamides as ccr9 antagonists
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
US9110030B2 (en) 2012-06-29 2015-08-18 Daniel A. Kerschensteiner Colorimetric gelatinase assay
US9651549B2 (en) 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
US9528941B2 (en) 2012-08-08 2016-12-27 Scanadu Incorporated Method and apparatus for determining analyte concentration by quantifying and interpreting color information captured in a continuous or periodic manner
CN104969068B (zh) 2012-08-08 2019-06-18 思勘度股份有限公司 用于在自动校准环境中执行及量化由特定浓度的生物分析物诱发的色彩改变的方法及设备
US9285323B2 (en) 2012-08-08 2016-03-15 Scanadu Incorporated Quantifying color changes of chemical test pads induced concentrations of biological analytes under different lighting conditions
AU2013305970B2 (en) 2012-08-21 2017-08-17 Saladax Biomedical Inc. Antibodies to aripiprazole haptens and use thereof
PL3462173T3 (pl) 2012-08-21 2021-08-16 Janssen Pharmaceutica Nv Przeciwciała przeciwko rysperydonowi i ich zastosowanie
EP2888277A4 (en) 2012-08-21 2016-05-18 Ortho Clinical Diagnostics Inc ANTIBODIES AGAINST PALIPERIDONE AND USE THEREOF
JP2015529199A (ja) 2012-08-21 2015-10-05 オルソ−クリニカル ダイアグノスティクス,インコーポレイティド パリペリドンハプテンに対する抗体及びその使用
PL2888592T3 (pl) 2012-08-21 2018-03-30 Janssen Pharmaceutica Nv Przeciwciała względem kwetiapiny i ich zastosowania
PT2888373T (pt) 2012-08-21 2018-06-12 Janssen Pharmaceutica Nv Anticorpos contra aripiprazole e seu uso
ES2822914T3 (es) 2012-08-21 2021-05-05 Janssen Pharmaceutica Nv Haptenos de aripiprazol y su uso en inmunoensayos
EP2888284B1 (en) 2012-08-21 2022-07-06 Janssen Pharmaceutica NV Antibodies to risperidone haptens and use thereof
EP3581195A1 (en) 2012-08-21 2019-12-18 Janssen Pharmaceutica NV Antibodies to olanzapine haptens and use thereof
PL2888286T3 (pl) 2012-08-21 2018-07-31 Janssen Pharmaceutica Nv Przeciwciała skierowane przeciwko haptenom kwetiapinowym i ich zastosowanie
ES2807902T3 (es) 2012-08-21 2021-02-24 Janssen Pharmaceutica Nv Anticuerpos para olanzapina y uso de los mismos
US20140072959A1 (en) 2012-09-12 2014-03-13 Force Diagnostics, Inc. Rapid tests for insurance underwriting
EP2904394A4 (en) * 2012-10-05 2016-11-16 Verax Biomedical Inc TEST WITH SEVERAL ANALYSIS
RU2015121732A (ru) 2012-11-15 2017-01-10 Орто-Клиникал Дайэгностикс, Инк. Калибровка анализов с использованием времени реакции
US9360479B2 (en) 2012-11-15 2016-06-07 Daniel Wang Rapid lateral flow assay method for low quantity liquid or dry samples
EP3203236A1 (en) 2012-11-15 2017-08-09 Ortho-Clinical Diagnostics, Inc. Quality/process control of a lateral flow assay device based on flow monitoring
EP2922964A2 (en) 2012-11-21 2015-09-30 Oslo Universitetssykehus HF Systems and methods for monitoring biological fluids
WO2014100732A1 (en) 2012-12-21 2014-06-26 Micronics, Inc. Fluidic circuits and related manufacturing methods
US10518262B2 (en) 2012-12-21 2019-12-31 Perkinelmer Health Sciences, Inc. Low elasticity films for microfluidic use
EP2935559B1 (en) 2012-12-21 2020-09-16 PerkinElmer Health Sciences, Inc. Fluorescence detection system
US20140234987A1 (en) 2013-01-02 2014-08-21 N-Dia, Inc. Methods for predicting time-to-delivery in pregnant women
US8968677B2 (en) 2013-01-22 2015-03-03 Quantum Design International, Inc. Frazil ice conjugate assay device and method
CA2841692C (en) 2013-02-12 2023-08-22 Zhong Ding Reagent zone deposition pattern
CA2902484C (en) 2013-02-26 2021-05-18 Astute Medical, Inc. Lateral flow assay with test strip retainer
EP2778679B1 (en) 2013-03-15 2017-09-27 Ortho-Clinical Diagnostics, Inc. Rotable disk-shaped fluid sample collection device
EP2777499B1 (en) 2013-03-15 2015-09-16 Ortho-Clinical Diagnostics Inc Rotatable fluid sample collection device
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
JP6472788B2 (ja) 2013-05-07 2019-02-20 マイクロニクス, インコーポレイテッド 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法
US10087440B2 (en) 2013-05-07 2018-10-02 Micronics, Inc. Device for preparation and analysis of nucleic acids
WO2014193804A1 (en) 2013-05-28 2014-12-04 Biogen Idec Ma Inc. Method of assessing risk of pml
US10364451B2 (en) 2013-05-30 2019-07-30 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
US10392611B2 (en) 2013-05-30 2019-08-27 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
CN108051590B (zh) 2013-09-13 2020-12-11 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
EP3077806B1 (en) 2013-12-06 2019-09-11 Ortho Clinical Diagnostics, Inc. Assay device having a wash port
JP6481192B2 (ja) * 2013-12-27 2019-03-13 地方独立行政法人大阪健康安全基盤研究所 クドア・セプテンプンクタータの迅速検出法
US10416158B2 (en) 2014-03-11 2019-09-17 Wisconsin Alumni Research Foundation Peptide MHCII tetramers to detect endogenous calnexin specific CD4 T cells
JP2016010338A (ja) * 2014-06-27 2016-01-21 国立大学法人東北大学 核酸検出用デバイス
US9903858B2 (en) 2014-07-23 2018-02-27 Ortho-Clinical Diagnostics, Inc. Multiplexing with single sample metering event to increase throughput
US10071373B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device having flow constrictions
US10073091B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral flow assay device
US11033896B2 (en) 2014-08-08 2021-06-15 Ortho-Clinical Diagnostics, Inc. Lateral-flow assay device with filtration flow control
US9863811B2 (en) 2014-08-15 2018-01-09 Scanadu Incorporated Precision luxmeter methods for digital cameras to quantify colors in uncontrolled lighting environments
JP6954834B2 (ja) 2014-10-06 2021-10-27 ケモセントリックス,インコーポレイティド CCケモカイン受容体9(CCR9)の阻害剤と抗α4β7インテグリン遮断抗体の併用療法
WO2016154530A1 (en) 2015-03-26 2016-09-29 Duke University Targeted therapeutic agents comprising multivalent protein-biopolymer fusions
CN115728482A (zh) 2015-04-06 2023-03-03 Blu诊断有限公司 用于检测唾液样品中的分析物的检测装置及使用方法
CA2983732A1 (en) 2015-04-23 2016-10-27 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Fungal detection using mannan epitope
US11002732B2 (en) 2015-05-19 2021-05-11 Ortho-Clinical Diagnostics, Inc. Method of improving liquid sample flow in assay device
AU2016301391B2 (en) 2015-08-04 2022-07-28 Duke University Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same
AU2016301231A1 (en) 2015-08-04 2018-02-22 Cd Diagnostics, Inc. Methods for detecting adverse local tissue reaction (ALTR) necrosis
EP3785799B1 (en) 2015-08-06 2023-01-18 Lia Diagnostics, Inc. Manufacturing methods for water dispersible assays
WO2017040352A1 (en) * 2015-08-28 2017-03-09 Pops! Diabetes Care, Inc. Blood glucose management system
US10808287B2 (en) 2015-10-23 2020-10-20 Rapid Pathogen Screening, Inc. Methods and devices for accurate diagnosis of infections
EP3371321A1 (en) 2015-11-06 2018-09-12 Oslo Universitetssykehus HF Methods and devices for detecting methanol poisoning using formate oxidase
EP3978619A1 (en) 2015-12-09 2022-04-06 Intuitive Biosciences, Inc. Automated silver enhancement system
JP6994461B2 (ja) 2015-12-17 2022-02-04 ヤンセン ファーマシューティカ エヌ.ベー. クエチアピンに対する抗体及びその使用
WO2017106501A1 (en) 2015-12-17 2017-06-22 Janssen Pharmaceutica Nv Antibodies to risperidone and use thereof
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
WO2017147186A1 (en) 2016-02-22 2017-08-31 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
WO2017178554A1 (en) 2016-04-13 2017-10-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for the rapid detection of the escherichia coli o25b-st131 clone
WO2017210476A1 (en) 2016-06-01 2017-12-07 Duke University Nonfouling biosensors
CN109964127A (zh) 2016-08-23 2019-07-02 Qoolabs有限公司 用于评估重组蛋白表达或报告基因表达的侧向流动检测
CN109890833A (zh) 2016-09-14 2019-06-14 杜克大学 用于递送亲水性药物的基于三嵌段多肽的纳米粒子
JP2020500150A (ja) 2016-09-23 2020-01-09 デューク ユニバーシティ 下限臨界溶液温度挙動を有する非反復かつ非構造的ポリペプチド
KR20190088513A (ko) 2016-11-23 2019-07-26 케모센트릭스, 인크. 국소 분절 사구체경화증의 치료 방법
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
CN113720832A (zh) 2016-12-28 2021-11-30 纽勤有限公司 器具分析装置和使用所述装置的方法
US11648200B2 (en) 2017-01-12 2023-05-16 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
WO2018152496A1 (en) 2017-02-17 2018-08-23 The Usa, As Represented By The Secretary, Dept. Of Health And Human Services Compositions and methods for the diagnosis and treatment of zika virus infection
EP4230649A3 (en) 2017-04-25 2023-10-25 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Antibodies and methods for the diagnosis and treatment of epstein barr virus infection
WO2018203145A1 (en) 2017-05-03 2018-11-08 Oslo Universitetssykehus Hf Systems and methods for monitoring biological fluids
US11554097B2 (en) 2017-05-15 2023-01-17 Duke University Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
KR102582297B1 (ko) 2017-05-19 2023-09-25 필립모리스 프로덕츠 에스.에이. 대상체의 흡연 상태를 구별하기 위한 진단 테스트
US11680083B2 (en) 2017-06-30 2023-06-20 Duke University Order and disorder as a design principle for stimuli-responsive biopolymer networks
EP3655430A1 (en) 2017-07-19 2020-05-27 The U.S.A. as represented by the Secretary, Department of Health and Human Services Antibodies and methods for the diagnosis and treatment of hepatitis b virus infection
RU2020113612A (ru) 2017-10-11 2021-11-12 Хемоцентрикс, Инк. Лечение фокально-сегментарного гломерулосклероза антагонистами ccr2
US20210171610A1 (en) 2018-05-02 2021-06-10 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Antibodies and methods for the diagnosis, prevention, and treatment of epstein barr virus infection
RU2682320C1 (ru) * 2018-05-07 2019-03-19 Владислав Николаевич Ласкавый Средство для профилактики вирусных инфекций
JPWO2019221250A1 (ja) * 2018-05-17 2021-11-11 株式会社テクノメデイカ 競合イムノクロマト分析法及びイムノクロマトセンサ
JP6530114B1 (ja) * 2018-06-27 2019-06-12 株式会社ニチレイバイオサイエンス メンブランシートのブロッキング方法
EP3820909B1 (en) 2018-07-11 2023-03-01 The United States of America, as represented by the Secretary, Department of Health and Human Services Monoclonal antibody for the detection of the antiretroviral drug emtricitabine (ftc, 2',3'-dideoxy-5-fluoro-3'-thiacytidine)
WO2020028806A1 (en) 2018-08-02 2020-02-06 Duke University Dual agonist fusion proteins
US11293839B2 (en) 2018-08-16 2022-04-05 Epitope Biotechnology Co., Ltd. Device for fecal sample collection and extraction
JP2022505934A (ja) 2018-10-24 2022-01-14 オラシュアテクノロジーズ, インコーポレイテッド 差異的アイソタイプ検出のためのラテラルフローアッセイ
US11300576B2 (en) 2019-01-29 2022-04-12 Arizona Board Of Regents On Behalf Of Arizona State University DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples
JP2020003477A (ja) * 2019-05-09 2020-01-09 株式会社ニチレイバイオサイエンス メンブランシートのブロッキング方法
EP3980182A1 (en) 2019-06-04 2022-04-13 Abbott Toxicology Limited Fluid specimen testing
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
CN110824177B (zh) * 2019-09-11 2021-06-11 润和生物医药科技(汕头)有限公司 一种快速检测试纸及其制备方法和应用
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
TW202203916A (zh) 2020-03-31 2022-02-01 美商卡默森屈有限公司 使用ccr9抑制劑及抗il—23阻斷抗體治療發炎性腸道疾病的組成物及方法
US20230295274A1 (en) 2020-07-27 2023-09-21 Single Cell Technology, Inc. Anti-sars coronavirus-2 spike protein antibodies
KR20240045314A (ko) 2021-08-18 2024-04-05 필립모리스 프로덕츠 에스.에이. 항체 및 이의 항원 결합 단편
WO2023163155A1 (ja) * 2022-02-28 2023-08-31 株式会社カネカ 検出用デバイス
WO2023239834A1 (en) * 2022-06-08 2023-12-14 Spotitearly Ltd. Machine learning (ml)-based disease-detection system using detection animals
WO2024030982A2 (en) 2022-08-02 2024-02-08 Diadem Spa Device for detection and prognostic assessment of neurodegenerative disorders

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941618A (es) * 1972-08-29 1974-04-19
US4022876A (en) * 1973-06-21 1977-05-10 Stanford Research Institute Mass spectrometric immunoassay
US4166105A (en) * 1973-07-30 1979-08-28 Block Engineering, Inc. Dye tagged reagent
CA1039649A (en) * 1973-08-30 1978-10-03 General Electric Company Method of forming multilayer immunologically complexed films
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
IT1087285B (it) * 1976-11-10 1985-06-04 Hoffmann La Roche Procedimento di determinazione immunologico
US4407943A (en) * 1976-12-16 1983-10-04 Millipore Corporation Immobilized antibody or antigen for immunoassay
US4200690A (en) * 1976-12-16 1980-04-29 Millipore Corporation Immunoassay with membrane immobilized antibody
US4122030A (en) * 1977-09-19 1978-10-24 Xerox Corporation Formation of colloidal dispersions of selenium by the locus control method
NL7807532A (nl) * 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
US4361537A (en) * 1979-01-12 1982-11-30 Thyroid Diagnostics, Inc. Test device and method for its use
US4235601A (en) * 1979-01-12 1980-11-25 Thyroid Diagnostics, Inc. Test device and method for its use
US4515893A (en) 1979-04-26 1985-05-07 Ortho Pharmaceutical Corporation Hybrid cell line for producing complement-fixing monoclonal antibody to human T cells
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
US4452901A (en) * 1980-03-20 1984-06-05 Ciba-Geigy Corporation Electrophoretically transferring electropherograms to nitrocellulose sheets for immuno-assays
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
DE3269567D1 (en) * 1981-04-29 1986-04-10 Ciba Geigy Ag New devices and kits for immunological analysis
DE3130924A1 (de) * 1981-08-05 1983-02-17 Röhm GmbH, 6100 Darmstadt Oberflaechenreiche systeme zur fixierung von nucleophile gruppen enthaltenden substraten
US4452886A (en) 1981-09-21 1984-06-05 Henry Robert P Novel photon absorbing or emitting polymers and their use as reagents in immunoassay systems
US5073484A (en) * 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
JPS59122950A (ja) * 1982-12-28 1984-07-16 Toray Ind Inc 生物学的に活性な物質の測定法およびそれに使用する標識剤
US4552839A (en) 1983-08-01 1985-11-12 Syntex (U.S.A.) Inc. Determination of analytes in particle-containing medium
GB8331514D0 (en) * 1983-11-25 1984-01-04 Janssen Pharmaceutica Nv Visualization method
US4703017C1 (en) * 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
US4756828A (en) 1984-04-12 1988-07-12 Syntex (U.S.A.) Inc. Chromatographic strip having non-compressed edges
JPS60231167A (ja) * 1984-05-01 1985-11-16 Nitsusui Seiyaku Kk 診断用スクリ−ニング試薬及びその調製法
FR2571146B1 (fr) * 1984-10-01 1988-02-26 Centre Nat Rech Scient Antigenes carcino-foetaux du pancreas humain et un procede de purification, antiserum contre ces antigenes et son procede de preparation et compositions diagnostiques les contenant
DE3445816C1 (de) * 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
EP0207152B1 (en) 1984-12-20 1992-12-30 Nycomed Pharma As Solid phase diffusion assay
GB8500698D0 (en) * 1985-01-11 1985-02-13 Unilever Plc Preparation of reagents
US4740468A (en) 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
JPS61224986A (ja) * 1985-03-28 1986-10-06 Eisai Co Ltd エラスタ−ゼ含有凍結乾燥物
GB8526741D0 (en) * 1985-10-30 1985-12-04 Boots Celltech Diagnostics Binding assay device
US4916056A (en) * 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
US4960692A (en) * 1986-03-18 1990-10-02 Fisher Scientific Company Assay employing binding pair members on particles and on a filter or membrane
AU602694B2 (en) * 1986-06-09 1990-10-25 Ortho Diagnostic Systems Inc. Improved colloidal gold membrane assay
US4818686A (en) * 1986-09-15 1989-04-04 Coulter Corporation Chemical blocking agent against non-specific binding or staining of an antibody specific for terminal deoxynucleotidyl transferase in biological specimens during immunoassay
US5310650A (en) * 1986-09-29 1994-05-10 Abbott Laboratoires Method and device for improved reaction kinetics in nucleic acid hybridizations
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
CA1303983C (en) * 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
US4748042A (en) * 1987-03-31 1988-05-31 V-Tech, Inc. Method and apparatus for imprinting membranes with patterns of antibody
JPH0746107B2 (ja) * 1987-04-27 1995-05-17 ユニリーバー・ナームローゼ・ベンノートシヤープ 検定法
DE3715485A1 (de) * 1987-05-09 1988-11-17 Boehringer Mannheim Gmbh Stabilisierung von ss-galactosidase
US4855240A (en) * 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
US4943522A (en) * 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
US4962023A (en) * 1987-06-22 1990-10-09 Louisiana State University, Agricultural And Mechanical College Single incubation immuno sorbent assay method using particle labels to detect test antigen specific antibodies in presence of other antibodies
US4954452A (en) * 1987-07-09 1990-09-04 Abbott Laboratories Non-metal colloidal particle immunoassay
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
US4859604A (en) * 1987-08-27 1989-08-22 Ampor, Inc. Composition for stabilization of diagnostic reagents
US5529901A (en) * 1987-11-19 1996-06-25 Staat Der Nederlanden Method for determining the presence or amount of analyte using a stable colloidal carbon sol
US5670381A (en) * 1988-01-29 1997-09-23 Abbott Laboratories Devices for performing ion-capture binding assays
US5281522A (en) * 1988-09-15 1994-01-25 Adeza Biomedical Corporation Reagents and kits for determination of fetal fibronectin in a vaginal sample
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5091318A (en) * 1990-04-13 1992-02-25 Abbott Laboratories Binding of allergens to a solid phase
US5266497A (en) * 1990-08-31 1993-11-30 Japan Synthetic Rubber Co., Ltd. Immunochromatographic assay with improved colored latex
US5451504A (en) * 1991-07-29 1995-09-19 Serex, Inc. Method and device for detecting the presence of analyte in a sample
US5310647A (en) * 1992-04-01 1994-05-10 Cherrystone Corporation Detection and measurement of destructive and polymer forming enzymes by colloidal flocculation
JPH0746107A (ja) * 1993-07-28 1995-02-14 Ricoh Co Ltd 出力切り替え回路
US5599668A (en) * 1994-09-22 1997-02-04 Abbott Laboratories Light scattering optical waveguide method for detecting specific binding events
US5712172A (en) * 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use

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Publication number Publication date
EP0299428A3 (en) 1991-07-31
DE3854951T3 (de) 2004-09-02
EP0299428B2 (en) 2004-01-02
ATE133788T1 (de) 1996-02-15
AU614294B2 (en) 1991-08-29
ES2085257T5 (es) 2004-09-16
JPH0760159B2 (ja) 1995-06-28
ES2085257T3 (es) 1996-06-01
EP0675361A2 (en) 1995-10-04
EP0675361B1 (en) 2002-11-06
ATE227427T1 (de) 2002-11-15
ES2186697T3 (es) 2003-05-16
DE3854951D1 (de) 1996-03-14
US5120643A (en) 1992-06-09
US20010006821A1 (en) 2001-07-05
DE3856544D1 (de) 2002-12-12
US6534320B2 (en) 2003-03-18
EP0299428B1 (en) 1996-01-31
EP0299428A2 (en) 1989-01-18
US5578577A (en) 1996-11-26
DE3854951T2 (de) 1996-11-07
AU1893388A (en) 1989-04-27
EP0675361A3 (en) 1995-10-25
CA1306675C (en) 1992-08-25
JPS6432169A (en) 1989-02-02

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