DD146461A5 - Verfahren zur herstellung von vindesinsulfat - Google Patents

Verfahren zur herstellung von vindesinsulfat Download PDF

Info

Publication number
DD146461A5
DD146461A5 DD79216158A DD21615879A DD146461A5 DD 146461 A5 DD146461 A5 DD 146461A5 DD 79216158 A DD79216158 A DD 79216158A DD 21615879 A DD21615879 A DD 21615879A DD 146461 A5 DD146461 A5 DD 146461A5
Authority
DD
German Democratic Republic
Prior art keywords
sulfuric acid
vindesine
acetonitrile
stirring
virtually
Prior art date
Application number
DD79216158A
Other languages
German (de)
English (en)
Inventor
Stanislaw Rolski
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD146461A5 publication Critical patent/DD146461A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
DD79216158A 1978-10-10 1979-10-10 Verfahren zur herstellung von vindesinsulfat DD146461A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US94959578A 1978-10-10 1978-10-10

Publications (1)

Publication Number Publication Date
DD146461A5 true DD146461A5 (de) 1981-02-11

Family

ID=25489302

Family Applications (1)

Application Number Title Priority Date Filing Date
DD79216158A DD146461A5 (de) 1978-10-10 1979-10-10 Verfahren zur herstellung von vindesinsulfat

Country Status (32)

Country Link
EP (1) EP0009996B1 (pl)
JP (1) JPS5553295A (pl)
KR (1) KR850000150B1 (pl)
AR (1) AR225153A1 (pl)
AT (1) AT370422B (pl)
AU (1) AU525702B2 (pl)
BE (1) BE879213A (pl)
BG (1) BG34763A3 (pl)
CA (1) CA1114817A (pl)
CH (2) CH645120A5 (pl)
CS (1) CS235503B2 (pl)
DD (1) DD146461A5 (pl)
DE (1) DE2964913D1 (pl)
DK (1) DK146823C (pl)
EG (1) EG14140A (pl)
ES (1) ES484827A1 (pl)
FI (1) FI70223C (pl)
FR (1) FR2438659A1 (pl)
GB (1) GB2031893B (pl)
GR (1) GR72394B (pl)
HU (1) HU180744B (pl)
IE (1) IE48958B1 (pl)
IL (1) IL58390A (pl)
LU (1) LU81763A1 (pl)
MY (1) MY8500569A (pl)
NZ (1) NZ191744A (pl)
PH (1) PH16092A (pl)
PL (1) PL117678B1 (pl)
PT (1) PT70269A (pl)
RO (1) RO77380A (pl)
YU (1) YU241179A (pl)
ZA (1) ZA795268B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558053A (en) * 1983-12-21 1985-12-10 Eli Lilly And Company Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
CN112592357B (zh) * 2020-12-22 2022-03-22 海南长春花药业有限公司 一种硫酸长春地辛的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
US4029663A (en) * 1975-07-10 1977-06-14 Eli Lilly And Company Dimeric anhydro-vinca derivatives
GR69783B (pl) * 1976-09-08 1982-07-07 Lilly Co Eli

Also Published As

Publication number Publication date
EG14140A (en) 1983-09-30
MY8500569A (en) 1985-12-31
AU5142779A (en) 1980-04-17
LU81763A1 (fr) 1980-01-24
CA1114817A (en) 1981-12-22
BE879213A (fr) 1980-04-08
HU180744B (en) 1983-04-29
DK422979A (da) 1980-04-11
FI793065A (fi) 1980-04-11
JPS628119B2 (pl) 1987-02-20
EP0009996A1 (en) 1980-04-16
AU525702B2 (en) 1982-11-25
RO77380A (ro) 1981-11-04
ES484827A1 (es) 1980-10-01
ATA658279A (de) 1982-08-15
AT370422B (de) 1983-03-25
FR2438659B1 (pl) 1983-03-18
JPS5553295A (en) 1980-04-18
IL58390A0 (en) 1980-01-31
KR850000150B1 (ko) 1985-02-28
FR2438659A1 (fr) 1980-05-09
FI70223C (fi) 1986-09-15
DK146823C (da) 1984-07-02
FI70223B (fi) 1986-02-28
AR225153A1 (es) 1982-02-26
DK146823B (da) 1984-01-16
IE48958B1 (en) 1985-06-26
ZA795268B (en) 1981-05-27
GR72394B (pl) 1983-11-01
EP0009996B1 (en) 1983-02-23
BG34763A3 (en) 1983-11-15
PH16092A (en) 1983-06-20
GB2031893A (en) 1980-04-30
CS235503B2 (en) 1985-05-15
YU241179A (en) 1983-01-21
IL58390A (en) 1982-07-30
IE791914L (en) 1980-04-10
GB2031893B (en) 1983-03-30
KR830001282A (ko) 1983-04-30
NZ191744A (en) 1981-05-29
PL117678B1 (en) 1981-08-31
CH649301A5 (fr) 1985-05-15
PL218756A1 (pl) 1980-06-16
CH645120A5 (fr) 1984-09-14
DE2964913D1 (en) 1983-03-31
PT70269A (de) 1979-11-01

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