KR830001282A - 빈데신 설페이트의 제조방법 - Google Patents

빈데신 설페이트의 제조방법 Download PDF

Info

Publication number
KR830001282A
KR830001282A KR1019790003467A KR790003467A KR830001282A KR 830001282 A KR830001282 A KR 830001282A KR 1019790003467 A KR1019790003467 A KR 1019790003467A KR 790003467 A KR790003467 A KR 790003467A KR 830001282 A KR830001282 A KR 830001282A
Authority
KR
South Korea
Prior art keywords
vindesine
producing
vindesine sulfate
sulfate
pure
Prior art date
Application number
KR1019790003467A
Other languages
English (en)
Other versions
KR850000150B1 (ko
Inventor
롤스키 스태니스로우
Original Assignee
아더 알. 웨일
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아더 알. 웨일, 일라이 릴리 앤드 캄파니 filed Critical 아더 알. 웨일
Publication of KR830001282A publication Critical patent/KR830001282A/ko
Application granted granted Critical
Publication of KR850000150B1 publication Critical patent/KR850000150B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)

Abstract

내용 없음

Description

빈데신 설페이트의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 순수한 빈데신 염기를 약 1% 농도로 아세토니트릴 도는 아세톤에 융해시키고 이용액에, 빈데신 디설페이트의 생성이 최소가 되는 범위내의 속도로 1몰의 1N 수성황산을 교반하면서 가하여 순수한 빈데신 모노설페이트를 수득함을 특징으로 하여 빈데신 설페이트를 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR7903467A 1978-10-10 1979-10-10 빈데신 설페이트의 제조방법 KR850000150B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94959578A 1978-10-10 1978-10-10
US949595 1992-09-23

Publications (2)

Publication Number Publication Date
KR830001282A true KR830001282A (ko) 1983-04-30
KR850000150B1 KR850000150B1 (ko) 1985-02-28

Family

ID=25489302

Family Applications (1)

Application Number Title Priority Date Filing Date
KR7903467A KR850000150B1 (ko) 1978-10-10 1979-10-10 빈데신 설페이트의 제조방법

Country Status (32)

Country Link
EP (1) EP0009996B1 (ko)
JP (1) JPS5553295A (ko)
KR (1) KR850000150B1 (ko)
AR (1) AR225153A1 (ko)
AT (1) AT370422B (ko)
AU (1) AU525702B2 (ko)
BE (1) BE879213A (ko)
BG (1) BG34763A3 (ko)
CA (1) CA1114817A (ko)
CH (2) CH649301A5 (ko)
CS (1) CS235503B2 (ko)
DD (1) DD146461A5 (ko)
DE (1) DE2964913D1 (ko)
DK (1) DK146823C (ko)
EG (1) EG14140A (ko)
ES (1) ES484827A1 (ko)
FI (1) FI70223C (ko)
FR (1) FR2438659A1 (ko)
GB (1) GB2031893B (ko)
GR (1) GR72394B (ko)
HU (1) HU180744B (ko)
IE (1) IE48958B1 (ko)
IL (1) IL58390A (ko)
LU (1) LU81763A1 (ko)
MY (1) MY8500569A (ko)
NZ (1) NZ191744A (ko)
PH (1) PH16092A (ko)
PL (1) PL117678B1 (ko)
PT (1) PT70269A (ko)
RO (1) RO77380A (ko)
YU (1) YU241179A (ko)
ZA (1) ZA795268B (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558053A (en) * 1983-12-21 1985-12-10 Eli Lilly And Company Naphthalene-1,5-disulfonate salts of dimeric indole-dihydroindole alkaloids
CN112592357B (zh) * 2020-12-22 2022-03-22 海南长春花药业有限公司 一种硫酸长春地辛的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
US4029663A (en) * 1975-07-10 1977-06-14 Eli Lilly And Company Dimeric anhydro-vinca derivatives
GR69783B (ko) * 1976-09-08 1982-07-07 Lilly Co Eli

Also Published As

Publication number Publication date
DK146823C (da) 1984-07-02
ATA658279A (de) 1982-08-15
FI70223C (fi) 1986-09-15
PH16092A (en) 1983-06-20
AU5142779A (en) 1980-04-17
EP0009996A1 (en) 1980-04-16
DK146823B (da) 1984-01-16
YU241179A (en) 1983-01-21
IL58390A (en) 1982-07-30
ES484827A1 (es) 1980-10-01
CS235503B2 (en) 1985-05-15
JPS628119B2 (ko) 1987-02-20
AT370422B (de) 1983-03-25
AU525702B2 (en) 1982-11-25
BG34763A3 (en) 1983-11-15
HU180744B (en) 1983-04-29
EG14140A (en) 1983-09-30
FR2438659B1 (ko) 1983-03-18
MY8500569A (en) 1985-12-31
IE791914L (en) 1980-04-10
AR225153A1 (es) 1982-02-26
DD146461A5 (de) 1981-02-11
EP0009996B1 (en) 1983-02-23
GB2031893B (en) 1983-03-30
KR850000150B1 (ko) 1985-02-28
CA1114817A (en) 1981-12-22
PL218756A1 (ko) 1980-06-16
RO77380A (ro) 1981-11-04
NZ191744A (en) 1981-05-29
FI70223B (fi) 1986-02-28
DE2964913D1 (en) 1983-03-31
JPS5553295A (en) 1980-04-18
IE48958B1 (en) 1985-06-26
PT70269A (de) 1979-11-01
PL117678B1 (en) 1981-08-31
IL58390A0 (en) 1980-01-31
ZA795268B (en) 1981-05-27
GR72394B (ko) 1983-11-01
DK422979A (da) 1980-04-11
FR2438659A1 (fr) 1980-05-09
BE879213A (fr) 1980-04-08
CH645120A5 (fr) 1984-09-14
CH649301A5 (fr) 1985-05-15
GB2031893A (en) 1980-04-30
FI793065A (fi) 1980-04-11
LU81763A1 (fr) 1980-01-24

Similar Documents

Publication Publication Date Title
KR830001269A (ko) 치환 프로린의 메르캅토 아실 유도체의 제조방법
SE7712986L (sv) Losning innehallande bestendig persyra
KR830005394A (ko) 금속 탈거 조성물
KR850001020A (ko) 탈산소제
KR870000103A (ko) 산화촉매의 제조방법
KR830001282A (ko) 빈데신 설페이트의 제조방법
KR830006286A (ko) 빈카민 사카리내이트의 제조방법
KR870003994A (ko) 도파민-β-하이드록시라제 억제제
KR890015022A (ko) 암 스크리닝 진단용의 개량된 밀론시약(1)
NL7901960A (nl) Stabiele waterige micro-emulsies van carbonzuur- of sulfonzuur- bevattende vinylharsen.
KR900007793A (ko) 용융된 시클로헥사논 옥심의 저장성 향상방법
KR880012226A (ko) 외 용 제
IT1092701B (it) Etere cis-e trans-3,3,5-trimetilcicloesiletilic o e loro miscugli come profumi,composizioni di profumi che li contengono e processo di produzione migliorato dell'etere trans-3,3,5-trimetil-cicloesil-etilico
KR830001308A (ko) 루틴폴리(h-) 설페이트를 제조하는 방법
Grant Cobalt complexes and le Chatelier
KR920009689A (ko) 안정화 이산화염소 수용액의 제조방법
ES428937A1 (es) Un procedimiento mejorado para la purificacion de acido sulfurico acuoso.
KR830007545A (ko) 프로스타글란딘의 제조방법
KR890003992A (ko) 반도체 팩케이지 리드부분의 납땜 또는 도금 공정의 전 처리를 하기 위한 조성물
JPS5265300A (en) Synthesis of 2-thioadenosines
KR830000172A (ko) 폐황산에 함유되어 있는 톨루엔설폰산유도체의 회수방법
KR840001179A (ko) 순수한 6,6-디요오도페니실란산의 제조방법
JPS52101671A (en) Desulfurization of exhaust gas
JPS52128318A (en) Production of acrylamide aqueous solution
KR880003665A (ko) 고령토로부터 탈색제의 제조방법