DD127966B3 - Verfahren zur herstellung von pyrrolidinderivaten - Google Patents
Verfahren zur herstellung von pyrrolidinderivaten Download PDFInfo
- Publication number
- DD127966B3 DD127966B3 DD19428776A DD19428776A DD127966B3 DD 127966 B3 DD127966 B3 DD 127966B3 DD 19428776 A DD19428776 A DD 19428776A DD 19428776 A DD19428776 A DD 19428776A DD 127966 B3 DD127966 B3 DD 127966B3
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- carbon atoms
- general formula
- abovementioned meaning
- formula
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT26326/75A IT1045043B (it) | 1975-08-13 | 1975-08-13 | Derivati pirrolidinici |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DD127966A5 DD127966A5 (de) | 1977-10-26 |
| DD127966B3 true DD127966B3 (de) | 1983-03-30 |
Family
ID=11219233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD19428776A DD127966B3 (de) | 1975-08-13 | 1976-08-11 | Verfahren zur herstellung von pyrrolidinderivaten |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4118396A (ru) |
| JP (1) | JPS5822034B2 (ru) |
| AR (1) | AR212176A1 (ru) |
| AT (1) | AT353783B (ru) |
| AU (1) | AU506651B2 (ru) |
| BE (1) | BE845099A (ru) |
| CA (1) | CA1077947A (ru) |
| CH (1) | CH624935A5 (ru) |
| CS (1) | CS214766B2 (ru) |
| DD (1) | DD127966B3 (ru) |
| DE (1) | DE2635853C2 (ru) |
| DK (1) | DK156055C (ru) |
| ES (1) | ES450643A1 (ru) |
| FI (1) | FI62290C (ru) |
| FR (1) | FR2320741A1 (ru) |
| GB (1) | GB1550160A (ru) |
| HU (1) | HU173742B (ru) |
| IN (1) | IN144871B (ru) |
| IT (1) | IT1045043B (ru) |
| MX (1) | MX4717E (ru) |
| NL (1) | NL179052C (ru) |
| NO (1) | NO146909C (ru) |
| NZ (1) | NZ181726A (ru) |
| PL (1) | PL101471B1 (ru) |
| SE (1) | SE420599B (ru) |
| SU (1) | SU663302A3 (ru) |
| YU (1) | YU40147B (ru) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1075280B (it) | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| IT1075564B (it) | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| GB1580559A (en) * | 1977-11-24 | 1980-12-03 | Wyeth John & Brother Ltd | Amide cerivatives |
| IT1141287B (it) * | 1979-06-13 | 1986-10-01 | Nattermann A & Cie | Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono |
| IT1131959B (it) * | 1979-08-09 | 1986-06-25 | Hoffmann La Roche | Derivati pirrolidinici |
| CH646149A5 (de) * | 1981-02-05 | 1984-11-15 | Hoffmann La Roche | Pyrrolidin-derivat. |
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| IT1206699B (it) * | 1984-02-27 | 1989-04-27 | Isf Spa | Procedimento per preparare derivati di pirrolidone. |
| CH666483A5 (de) * | 1985-01-16 | 1988-07-29 | Lonza Ag | Verfahren zur herstellung von thiotetronsaeure. |
| IT1190378B (it) * | 1985-06-21 | 1988-02-16 | Isf Spa | Derivati pirrolidonici |
| EP0223328B1 (en) | 1985-07-26 | 1992-01-29 | Denki Kagaku Kogyo Kabushiki Kaisha | Process for producing oxiracetam |
| CH668423A5 (de) * | 1986-06-19 | 1988-12-30 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen. |
| HU195773B (en) * | 1985-09-24 | 1988-07-28 | Lonza Ag | Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid |
| IL80071A0 (en) * | 1985-09-24 | 1986-12-31 | Lonza Ag | Pyrrolidine acetamide derivatives |
| US4677114A (en) * | 1985-11-22 | 1987-06-30 | Warner-Lambert Company | Pyrrolidone-2 derivatives and pharmaceutical compositions thereof |
| CH668424A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung. |
| CH668422A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure. |
| IT1224168B (it) * | 1986-08-01 | 1990-09-26 | Finanziaria R F Spa Ora Finanz | Derivati del pirrolidin-2-one ad attivita' nootropa |
| CH667655A5 (de) * | 1986-09-24 | 1988-10-31 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen. |
| CH670644A5 (ru) * | 1986-12-18 | 1989-06-30 | Lonza Ag | |
| US5202345A (en) * | 1987-08-19 | 1993-04-13 | Shionogi & Co., Ltd. | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| CA1305148C (en) * | 1987-08-19 | 1992-07-14 | Hiromu Matsumura | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| DE3813416A1 (de) * | 1988-04-21 | 1989-11-02 | Hoechst Ag | 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte |
| JP2660201B2 (ja) * | 1988-08-05 | 1997-10-08 | 塩野義製薬株式会社 | 新規ピロロ［１，４］ベンゾジアゼピン誘導体および老人性痴呆薬 |
| JPH02115162A (ja) * | 1988-09-06 | 1990-04-27 | Lonza Ag | ５―アルキルテトラム酸およびその製造方法 |
| IL93051A0 (en) * | 1989-01-17 | 1990-11-05 | Hoffmann La Roche | ((5-oxo-2-pyrrolidinyl)methyl)cyclohexaneacetamides,their preparation and pharmaceutical compositions containing them |
| FI95034C (fi) * | 1989-03-15 | 1995-12-11 | Lonza Ag | Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi |
| CH680293A5 (ru) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
| JP3038032B2 (ja) * | 1991-03-25 | 2000-05-08 | 日清製粉株式会社 | 血小板凝集抑制薬 |
| WO2002053153A1 (fr) | 2000-12-28 | 2002-07-11 | Daiichi Pharmaceutical Co., Ltd. | Medicaments permettant de traiter et de prevenir une douleur neurologique |
| EP1993998B1 (en) * | 2005-12-07 | 2013-08-21 | UCB Pharma, S.A. | 3-carboxy- 2-oxo-1 -pyrrolidine derivatives and their uses |
| DK3260118T3 (da) * | 2008-10-16 | 2021-04-19 | Univ Johns Hopkins | Fremgangsmåder og sammensætninger til forbedring af kognitiv funktion |
| CA2789014C (en) * | 2010-02-09 | 2019-01-15 | Michela Gallagher | Methods and compositions for improving cognitive function |
| JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
| CN105820102A (zh) * | 2016-05-10 | 2016-08-03 | 武汉工程大学 | 奥拉西坦的合成工艺 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1011886B (de) * | 1952-04-29 | 1957-07-11 | Waldemar Kutscher Dr Ing Dr Me | Verfahren zur Herstellung von Aminoalkylpyrrolen |
| GB1309692A (en) * | 1970-02-13 | 1973-03-14 | Ucb Sa | N-substituted lactams |
| GB1039113A (en) * | 1964-08-06 | 1966-08-17 | Ucb Sa | New n-substituted lactams |
| US3541111A (en) * | 1968-05-08 | 1970-11-17 | Du Pont | Pyrrolinecarboxanilide compounds |
| US3577432A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-phenoxypyrrolidines |
-
1975
- 1975-08-13 IT IT26326/75A patent/IT1045043B/it active Protection Beyond IP Right Term
-
1976
- 1976-08-09 CA CA258,677A patent/CA1077947A/en not_active Expired
- 1976-08-09 AT AT589476A patent/AT353783B/de active
- 1976-08-09 AR AR264270A patent/AR212176A1/es active
- 1976-08-09 CS CS765174A patent/CS214766B2/cs unknown
- 1976-08-09 IN IN1433/CAL/1976A patent/IN144871B/en unknown
- 1976-08-09 NZ NZ181726A patent/NZ181726A/xx unknown
- 1976-08-10 DE DE2635853A patent/DE2635853C2/de not_active Expired
- 1976-08-10 SE SE7608938A patent/SE420599B/xx not_active IP Right Cessation
- 1976-08-10 GB GB33243/76A patent/GB1550160A/en not_active Expired
- 1976-08-10 YU YU1964/76A patent/YU40147B/xx unknown
- 1976-08-10 HU HU76IE754A patent/HU173742B/hu not_active IP Right Cessation
- 1976-08-11 BE BE6045634A patent/BE845099A/xx not_active IP Right Cessation
- 1976-08-11 FR FR7624482A patent/FR2320741A1/fr active Granted
- 1976-08-11 NO NO762791A patent/NO146909C/no unknown
- 1976-08-11 DD DD19428776A patent/DD127966B3/de unknown
- 1976-08-11 CH CH1022576A patent/CH624935A5/de not_active IP Right Cessation
- 1976-08-11 NL NLAANVRAGE7608946,A patent/NL179052C/xx not_active IP Right Cessation
- 1976-08-11 JP JP51095930A patent/JPS5822034B2/ja not_active Expired
- 1976-08-12 SU SU762388323A patent/SU663302A3/ru active
- 1976-08-12 AU AU16797/76A patent/AU506651B2/en not_active Expired
- 1976-08-12 ES ES450643A patent/ES450643A1/es not_active Expired
- 1976-08-12 US US05/713,901 patent/US4118396A/en not_active Expired - Lifetime
- 1976-08-12 DK DK365176A patent/DK156055C/da not_active IP Right Cessation
- 1976-08-12 FI FI762314A patent/FI62290C/fi not_active IP Right Cessation
- 1976-08-12 PL PL1976191773A patent/PL101471B1/pl unknown
- 1976-08-13 MX MX762906U patent/MX4717E/es unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DD127966B3 (de) | Verfahren zur herstellung von pyrrolidinderivaten | |
| DE2760372C2 (ru) | ||
| DE1620024C3 (de) | 3'-Pyridylmethyl-2-(4-chlorphenoxy)-2-methylpropionat | |
| DE3346573A1 (de) | 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung | |
| DE2002840B2 (de) | Neue 23,5-trisubstit-2'-Hydroxy-6,7-benzomorphane | |
| DE2918523A1 (de) | Lactam-n-essigsaeuren und deren amide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel | |
| DE2009408A1 (de) | 5-Pyridyl-2-imidazolone | |
| DE1620191A1 (de) | Verfahren zur Herstellung von N-substituierten alpha-Pyrrolidonen | |
| DE2831761A1 (de) | 2,3,6-substituierte-4-pyronderivate und ihre verwendung | |
| DE2044172A1 (de) | Neue Pyrroldenvate, ein Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimittelzubereitungen | |
| DE2635854A1 (de) | Pyrrolin-2-on-derivate, verfahren zu ihrer herstellung und sie enthaltendes arzneimittel | |
| DE3642497A1 (de) | Substituierte aminopropionsaeureamide, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte | |
| DE2046904A1 (de) | Indohzinessigsauren und Verfahren zu ihrer Herstellung | |
| DE2756852A1 (de) | 1-amino-niedrig-alkyl-3,4-diphenyl- 1h-pyrazole | |
| DE1643265C3 (de) | Kernsubstituierte 2-Aminomethylbenzhydrole, Verfahren zu deren Herstellung und Arzneimittel auf der Basis dieser Verbindungen | |
| AT208872B (de) | Verfahren zur Herstellung neuer 1,4-Diazacycloheptane | |
| DE3141585A1 (de) | 1,8-dihydroxy-9-anthron-addukte, verfahren zu ihrer herstellung und ihre verwendung in der human- und veterinaermedizin sowie in der kosmetik | |
| DE1147946B (de) | Verfahren zur Herstellung von Phenthiazinderivaten und ihren Saeureadditionssalzen | |
| DE1620170C3 (de) | Neue Phenothiazinderivate und Verfahren zu ihrer Herstellung | |
| DE1901167C3 (de) | Substituierte Indole, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen | |
| DE2404924A1 (de) | Ergolinderivate | |
| DE1543423A1 (de) | Verfahren zur Herstellung von 2-Methylencycloalkancarbonsaeuren und deren Derivaten | |
| AT356665B (de) | Verfahren zum herstellen neuer chinuclidin- derivate, ihren stereoisomeren, optischen isomeren und salzen | |
| AT374792B (de) | Verfahren zur herstellung eines neuen pyrrolidin -derivates | |
| AT294063B (de) | Verfahren zur Herstellung von neuen 2-Alkyl-4,5-diphenylpyrrolderivaten |