DK156055C - Analogifremgangsmaade til fremstilling af pyrrolidin-2-onderivater - Google Patents
Analogifremgangsmaade til fremstilling af pyrrolidin-2-onderivaterInfo
- Publication number
- DK156055C DK156055C DK365176A DK365176A DK156055C DK 156055 C DK156055 C DK 156055C DK 365176 A DK365176 A DK 365176A DK 365176 A DK365176 A DK 365176A DK 156055 C DK156055 C DK 156055C
- Authority
- DK
- Denmark
- Prior art keywords
- pyrrolidin
- analogy
- substances
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT26326/75A IT1045043B (it) | 1975-08-13 | 1975-08-13 | Derivati pirrolidinici |
| IT2632675 | 1975-08-13 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK365176A DK365176A (da) | 1977-02-14 |
| DK156055B DK156055B (da) | 1989-06-19 |
| DK156055C true DK156055C (da) | 1989-12-04 |
Family
ID=11219233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK365176A DK156055C (da) | 1975-08-13 | 1976-08-12 | Analogifremgangsmaade til fremstilling af pyrrolidin-2-onderivater |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4118396A (ru) |
| JP (1) | JPS5822034B2 (ru) |
| AR (1) | AR212176A1 (ru) |
| AT (1) | AT353783B (ru) |
| AU (1) | AU506651B2 (ru) |
| BE (1) | BE845099A (ru) |
| CA (1) | CA1077947A (ru) |
| CH (1) | CH624935A5 (ru) |
| CS (1) | CS214766B2 (ru) |
| DD (1) | DD127966B3 (ru) |
| DE (1) | DE2635853C2 (ru) |
| DK (1) | DK156055C (ru) |
| ES (1) | ES450643A1 (ru) |
| FI (1) | FI62290C (ru) |
| FR (1) | FR2320741A1 (ru) |
| GB (1) | GB1550160A (ru) |
| HU (1) | HU173742B (ru) |
| IN (1) | IN144871B (ru) |
| IT (1) | IT1045043B (ru) |
| MX (1) | MX4717E (ru) |
| NL (1) | NL179052C (ru) |
| NO (1) | NO146909C (ru) |
| NZ (1) | NZ181726A (ru) |
| PL (1) | PL101471B1 (ru) |
| SE (1) | SE420599B (ru) |
| SU (1) | SU663302A3 (ru) |
| YU (1) | YU40147B (ru) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1075564B (it) * | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| IT1075280B (it) | 1977-02-11 | 1985-04-22 | Isf Spa | Procedimento per la preparazione di derivati pirrolidinici |
| GB1580559A (en) * | 1977-11-24 | 1980-12-03 | Wyeth John & Brother Ltd | Amide cerivatives |
| IT1141287B (it) * | 1979-06-13 | 1986-10-01 | Nattermann A & Cie | Ammidi di acidi pirrolidin-(2)-on-(1)-ilalchil-carbossilici,procedimento per la loro preparazione e prodotti medicinali che le contengono |
| IT1131959B (it) * | 1979-08-09 | 1986-06-25 | Hoffmann La Roche | Derivati pirrolidinici |
| CH646149A5 (de) * | 1981-02-05 | 1984-11-15 | Hoffmann La Roche | Pyrrolidin-derivat. |
| FR2515179A1 (fr) * | 1981-07-24 | 1983-04-29 | Hoffmann La Roche | Derives de pyrrolidine, leur procede de preparation, les intermediaires pour leur synthese et leur application therapeutique |
| IT1206699B (it) * | 1984-02-27 | 1989-04-27 | Isf Spa | Procedimento per preparare derivati di pirrolidone. |
| CH666483A5 (de) * | 1985-01-16 | 1988-07-29 | Lonza Ag | Verfahren zur herstellung von thiotetronsaeure. |
| IT1190378B (it) * | 1985-06-21 | 1988-02-16 | Isf Spa | Derivati pirrolidonici |
| EP0223328B1 (en) | 1985-07-26 | 1992-01-29 | Denki Kagaku Kogyo Kabushiki Kaisha | Process for producing oxiracetam |
| IL80071A0 (en) * | 1985-09-24 | 1986-12-31 | Lonza Ag | Pyrrolidine acetamide derivatives |
| HU195773B (en) * | 1985-09-24 | 1988-07-28 | Lonza Ag | Process for preparing alkyl esters of 4-alkoxy-3-pyrrolin-2-on-1-yl-acetic acid |
| CH668423A5 (de) * | 1986-06-19 | 1988-12-30 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-3-pyrrolin-2-onen. |
| US4677114A (en) * | 1985-11-22 | 1987-06-30 | Warner-Lambert Company | Pyrrolidone-2 derivatives and pharmaceutical compositions thereof |
| CH668424A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on-l-yl-acetamid, dessen herstellung und verwendung. |
| CH668422A5 (de) * | 1986-06-26 | 1988-12-30 | Lonza Ag | 4-benzyloxy-3-pyrrolin-2-on, dessen herstellung und verwendung zur synthese von tetramsaeure. |
| IT1224168B (it) * | 1986-08-01 | 1990-09-26 | Finanziaria R F Spa Ora Finanz | Derivati del pirrolidin-2-one ad attivita' nootropa |
| CH667655A5 (de) * | 1986-09-24 | 1988-10-31 | Lonza Ag | Verfahren zur herstellung von 4-alkoxy-2(5h)-thiophenonen. |
| CH670644A5 (ru) * | 1986-12-18 | 1989-06-30 | Lonza Ag | |
| CA1305148C (en) * | 1987-08-19 | 1992-07-14 | Hiromu Matsumura | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| US5202345A (en) * | 1987-08-19 | 1993-04-13 | Shionogi & Co., Ltd. | Carbamoylpyrrolidone derivatives and drugs for senile dementia |
| DE3813416A1 (de) * | 1988-04-21 | 1989-11-02 | Hoechst Ag | 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte |
| JP2660201B2 (ja) * | 1988-08-05 | 1997-10-08 | 塩野義製薬株式会社 | 新規ピロロ［１，４］ベンゾジアゼピン誘導体および老人性痴呆薬 |
| DE58909320D1 (de) * | 1988-09-06 | 1995-08-03 | Lonza Ag | Verfahren zur Herstellung von 5-Alkyltetramsäuren. |
| AU625157B2 (en) * | 1989-01-17 | 1992-07-02 | F. Hoffmann-La Roche Ag | Cyclohexaneacetamide derivatives |
| FI95034C (fi) * | 1989-03-15 | 1995-12-11 | Lonza Ag | Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi |
| CH680293A5 (ru) * | 1990-06-26 | 1992-07-31 | Lonza Ag | |
| JP3038032B2 (ja) * | 1991-03-25 | 2000-05-08 | 日清製粉株式会社 | 血小板凝集抑制薬 |
| DE60138733D1 (de) | 2000-12-28 | 2009-06-25 | Hamilton Pharmaceuticals Inc | Arzneimittel zur behandlung und vermeidung neurogener schmerzen |
| CA2632453A1 (en) * | 2005-12-07 | 2007-06-14 | Ucb Pharma, S.A. | 3-carboxy- 2-oxo-1 -pyrrolidine derivatives and their uses |
| CN107243007A (zh) | 2008-10-16 | 2017-10-13 | 约翰斯.霍普金斯大学 | 改善认知功能的方法和组合物 |
| BR112012019923A2 (pt) * | 2010-02-09 | 2016-08-09 | Univ Johns Hopkins | métodos e composições para melhorar a função cognitiva |
| CA2891122C (en) | 2012-11-14 | 2021-07-20 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| EP2968220B1 (en) | 2013-03-15 | 2021-05-05 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
| CN107810002B (zh) | 2015-05-22 | 2021-01-05 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
| CN105820102A (zh) * | 2016-05-10 | 2016-08-03 | 武汉工程大学 | 奥拉西坦的合成工艺 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1011886B (de) * | 1952-04-29 | 1957-07-11 | Waldemar Kutscher Dr Ing Dr Me | Verfahren zur Herstellung von Aminoalkylpyrrolen |
| GB1039113A (en) * | 1964-08-06 | 1966-08-17 | Ucb Sa | New n-substituted lactams |
| GB1309692A (en) * | 1970-02-13 | 1973-03-14 | Ucb Sa | N-substituted lactams |
| US3541111A (en) * | 1968-05-08 | 1970-11-17 | Du Pont | Pyrrolinecarboxanilide compounds |
| US3577432A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-phenoxypyrrolidines |
-
1975
- 1975-08-13 IT IT26326/75A patent/IT1045043B/it active Protection Beyond IP Right Term
-
1976
- 1976-08-09 AR AR264270A patent/AR212176A1/es active
- 1976-08-09 AT AT589476A patent/AT353783B/de active
- 1976-08-09 CA CA258,677A patent/CA1077947A/en not_active Expired
- 1976-08-09 IN IN1433/CAL/1976A patent/IN144871B/en unknown
- 1976-08-09 NZ NZ181726A patent/NZ181726A/xx unknown
- 1976-08-09 CS CS765174A patent/CS214766B2/cs unknown
- 1976-08-10 GB GB33243/76A patent/GB1550160A/en not_active Expired
- 1976-08-10 YU YU1964/76A patent/YU40147B/xx unknown
- 1976-08-10 DE DE2635853A patent/DE2635853C2/de not_active Expired
- 1976-08-10 SE SE7608938A patent/SE420599B/xx not_active IP Right Cessation
- 1976-08-10 HU HU76IE754A patent/HU173742B/hu not_active IP Right Cessation
- 1976-08-11 FR FR7624482A patent/FR2320741A1/fr active Granted
- 1976-08-11 CH CH1022576A patent/CH624935A5/de not_active IP Right Cessation
- 1976-08-11 NO NO762791A patent/NO146909C/no unknown
- 1976-08-11 DD DD19428776A patent/DD127966B3/de unknown
- 1976-08-11 NL NLAANVRAGE7608946,A patent/NL179052C/xx not_active IP Right Cessation
- 1976-08-11 JP JP51095930A patent/JPS5822034B2/ja not_active Expired
- 1976-08-11 BE BE6045634A patent/BE845099A/xx not_active IP Right Cessation
- 1976-08-12 PL PL1976191773A patent/PL101471B1/pl unknown
- 1976-08-12 FI FI762314A patent/FI62290C/fi not_active IP Right Cessation
- 1976-08-12 ES ES450643A patent/ES450643A1/es not_active Expired
- 1976-08-12 US US05/713,901 patent/US4118396A/en not_active Expired - Lifetime
- 1976-08-12 DK DK365176A patent/DK156055C/da not_active IP Right Cessation
- 1976-08-12 SU SU762388323A patent/SU663302A3/ru active
- 1976-08-12 AU AU16797/76A patent/AU506651B2/en not_active Expired
- 1976-08-13 MX MX762906U patent/MX4717E/es unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |