DK249975A - Fremgangsmade til fremstilling af 8-thiomethylergolin-forbindelser - Google Patents

Fremgangsmade til fremstilling af 8-thiomethylergolin-forbindelser

Info

Publication number
DK249975A
DK249975A DK249975A DK249975A DK249975A DK 249975 A DK249975 A DK 249975A DK 249975 A DK249975 A DK 249975A DK 249975 A DK249975 A DK 249975A DK 249975 A DK249975 A DK 249975A
Authority
DK
Denmark
Prior art keywords
thiomethylergoline
compounds
preparation
thiomethylergoline compounds
Prior art date
Application number
DK249975A
Other languages
English (en)
Other versions
DK144160B (da
DK144160C (da
Inventor
E C Kornfeld
N J Bach
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK249975A publication Critical patent/DK249975A/da
Publication of DK144160B publication Critical patent/DK144160B/da
Application granted granted Critical
Publication of DK144160C publication Critical patent/DK144160C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK249975A 1974-06-06 1975-06-04 Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner DK144160C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US477136A US3901894A (en) 1974-06-06 1974-06-06 8-thiomethylergolines
US47713674 1974-06-06

Publications (3)

Publication Number Publication Date
DK249975A true DK249975A (da) 1975-12-07
DK144160B DK144160B (da) 1981-12-28
DK144160C DK144160C (da) 1982-06-07

Family

ID=23894677

Family Applications (1)

Application Number Title Priority Date Filing Date
DK249975A DK144160C (da) 1974-06-06 1975-06-04 Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner

Country Status (27)

Country Link
US (1) US3901894A (da)
JP (1) JPS582946B2 (da)
AR (1) AR210736A1 (da)
AT (1) AT344333B (da)
AU (1) AU507574B2 (da)
BE (1) BE829887A (da)
BG (1) BG24812A3 (da)
CA (1) CA1071623A (da)
CH (1) CH617196A5 (da)
CS (1) CS199591B2 (da)
DD (1) DD120438A5 (da)
DE (1) DE2524575A1 (da)
DK (1) DK144160C (da)
ES (1) ES438313A1 (da)
FR (1) FR2273542A1 (da)
GB (1) GB1505296A (da)
HU (1) HU173590B (da)
IE (1) IE41474B1 (da)
IL (1) IL47424A (da)
NL (1) NL180911C (da)
PH (1) PH10992A (da)
PL (1) PL95738B1 (da)
RO (1) RO77543A (da)
SE (1) SE420095B (da)
SU (1) SU613724A3 (da)
YU (1) YU145575A (da)
ZA (1) ZA753638B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (it) * 1977-07-05 1988-03-31 Simes Derivati di ergoline-2-tioeteri e loro solfossidi
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) * 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (de) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische zubereitungen mit zytostatischer wirkung
FR2526797A1 (fr) * 1982-05-12 1983-11-18 Roussel Uclaf Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (fr) * 1985-11-13 1988-09-02 Roussel Uclaf Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
ATE424414T1 (de) * 2001-06-08 2009-03-15 Sod Conseils Rech Applic Chimere somatostatin-dopamin-analoga
US7019140B2 (en) * 2002-03-15 2006-03-28 Antibioticos S.P.A. Process for the synthesis of pergolide
WO2014070965A2 (en) 2012-11-01 2014-05-08 Ipsen Pharma S.A.S Somatostatin analogs and dimers thereof
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
NZ728804A (en) 2014-09-25 2022-10-28 Boehringer Ingelheim Vetmedica Gmbh Combination treatment of sglt2 inhibitors and dopamine agonists for preventing metabolic disorders in equine animals
WO2019234069A1 (en) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (da) * 1967-03-16 1968-07-15
DE1935556A1 (de) * 1969-07-12 1971-01-21 Hoechst Ag Verfahren zur Herstellung von Lysergol
JPS5012398A (da) * 1973-06-08 1975-02-07

Also Published As

Publication number Publication date
NL180911C (nl) 1987-05-18
IL47424A (en) 1979-11-30
NL7506584A (nl) 1975-12-09
BE829887A (fr) 1975-12-05
AR210736A1 (es) 1977-09-15
ES438313A1 (es) 1977-05-16
FR2273542A1 (fr) 1976-01-02
CA1071623A (en) 1980-02-12
CH617196A5 (da) 1980-05-14
IE41474B1 (en) 1980-01-16
PH10992A (en) 1977-10-20
SE7506327L (sv) 1975-12-08
JPS50160300A (da) 1975-12-25
DE2524575A1 (de) 1975-12-18
BG24812A3 (en) 1978-05-12
US3901894A (en) 1975-08-26
FR2273542B1 (da) 1978-10-06
JPS582946B2 (ja) 1983-01-19
RO77543A (ro) 1982-02-26
ZA753638B (en) 1977-01-26
IL47424A0 (en) 1975-08-31
SE420095B (sv) 1981-09-14
DD120438A5 (da) 1976-06-12
AU507574B2 (en) 1980-02-21
IE41474L (en) 1975-12-06
DK144160B (da) 1981-12-28
CS199591B2 (en) 1980-07-31
HU173590B (hu) 1979-06-28
AU8182775A (en) 1976-12-09
ATA427975A (de) 1977-11-15
YU145575A (en) 1982-02-28
SU613724A3 (ru) 1978-06-30
AT344333B (de) 1978-07-10
NL180911B (nl) 1986-12-16
GB1505296A (en) 1978-03-30
PL95738B1 (pl) 1977-11-30
DK144160C (da) 1982-06-07

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