IE41474L - Thiomethylergolines - Google Patents



Publication number
IE41474L IE751221A IE122175A IE41474L IE 41474 L IE41474 L IE 41474L IE 751221 A IE751221 A IE 751221A IE 122175 A IE122175 A IE 122175A IE 41474 L IE41474 L IE 41474L
Prior art keywords
Prior art date
Application number
Other versions
IE41474B1 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US477136A priority Critical patent/US3901894A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IE41474L publication Critical patent/IE41474L/en
Publication of IE41474B1 publication Critical patent/IE41474B1/en



    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A61P35/00Antineoplastic agents
IE1221/75A 1974-06-06 1975-06-03 -thiomethylergolines IE41474B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US477136A US3901894A (en) 1974-06-06 1974-06-06 8-thiomethylergolines

Publications (2)

Publication Number Publication Date
IE41474L true IE41474L (en) 1975-12-06
IE41474B1 IE41474B1 (en) 1980-01-16



Family Applications (1)

Application Number Title Priority Date Filing Date
IE1221/75A IE41474B1 (en) 1974-06-06 1975-06-03 -thiomethylergolines

Country Status (27)

Country Link
US (1) US3901894A (en)
JP (1) JPS582946B2 (en)
AR (1) AR210736A1 (en)
AT (1) AT344333B (en)
AU (1) AU507574B2 (en)
BE (1) BE829887A (en)
BG (1) BG24812A3 (en)
CA (1) CA1071623A (en)
CH (1) CH617196A5 (en)
CS (1) CS199591B2 (en)
DD (1) DD120438A5 (en)
DE (1) DE2524575A1 (en)
DK (1) DK144160C (en)
ES (1) ES438313A1 (en)
FR (1) FR2273542B1 (en)
GB (1) GB1505296A (en)
HU (1) HU173590B (en)
IE (1) IE41474B1 (en)
IL (1) IL47424A (en)
NL (1) NL180911C (en)
PH (1) PH10992A (en)
PL (1) PL95738B1 (en)
RO (1) RO77543A (en)
SE (1) SE420095B (en)
SU (1) SU613724A3 (en)
YU (1) YU145575A (en)
ZA (1) ZA7503638B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (en) * 1977-07-05 1988-03-31 Simes Ergoline derivatives of 2-thioethers and their sulfoxides
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) * 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (en) * 1982-05-03 1983-11-03 Schering Ag Pharmaceutical preparations with a cytostatic effect
FR2526797B1 (en) * 1982-05-12 1984-12-28 Roussel Uclaf
CH649998A5 (en) * 1982-08-09 1985-06-28 Sandoz Ag Ergol derivatives, a method for their production and healing agents, containing these ergol derivatives as an active substance.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (en) * 1985-11-13 1988-09-02 Roussel Uclaf Use of ergolin derivatives for obtaining a geriatric medicine
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
MXPA03011321A (en) * 2001-06-08 2004-12-06 Conseils De Rech S Et D Aplica Somatostatin-dopamine chimeric analogs.
AU2003221494A1 (en) * 2002-03-15 2003-09-29 Antibioticos S.P.A. Process for the synthesis of pergolide
TWI523863B (en) 2012-11-01 2016-03-01 艾普森藥品公司 Somatostatin-dopamine chimeric analogs
JP2016503402A (en) 2012-11-01 2016-02-04 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエIpsen Pharma S.A.S. Somatostatin analogs and dimers thereof
US20190374534A1 (en) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507248A (en) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke A process for preparing D-6-methylergolin (I) ylacetic acid
DE1935556A1 (en) * 1969-07-12 1971-01-21 Hoechst Ag A process for preparing lysergol
JPS5012398A (en) * 1973-06-08 1975-02-07

Also Published As

Publication number Publication date
CH617196A5 (en) 1980-05-14
CA1071623A (en) 1980-02-12
JPS50160300A (en) 1975-12-25
AU8182775A (en) 1976-12-09
DD120438A5 (en) 1976-06-12
DE2524575A1 (en) 1975-12-18
JPS582946B2 (en) 1983-01-19
DK249975A (en) 1975-12-07
FR2273542B1 (en) 1978-10-06
FR2273542A1 (en) 1976-01-02
NL180911C (en) 1987-05-18
ATA427975A (en) 1977-11-15
BE829887A1 (en)
AT344333B (en) 1978-07-10
IL47424D0 (en) 1975-08-31
GB1505296A (en) 1978-03-30
CA1071623A1 (en)
AR210736A1 (en) 1977-09-15
YU145575A (en) 1982-02-28
ZA7503638B (en) 1977-01-26
DK144160B (en) 1981-12-28
BE829887A (en) 1975-12-05
RO77543A (en) 1982-02-26
PH10992A (en) 1977-10-20
AU507574B2 (en) 1980-02-21
SU613724A3 (en) 1978-06-30
BG24812A3 (en) 1978-05-12
US3901894A (en) 1975-08-26
CS199591B2 (en) 1980-07-31
HU173590B (en) 1979-06-28
IL47424A (en) 1979-11-30
NL7506584A (en) 1975-12-09
IE41474B1 (en) 1980-01-16
ES438313A1 (en) 1977-05-16
PL95738B1 (en) 1977-11-30
DK144160C (en) 1982-06-07
SE420095B (en) 1981-09-14
SE7506327L (en) 1975-12-08
NL180911B (en) 1986-12-16

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