BE829887A - 8-thiomethylergolines - Google Patents

8-thiomethylergolines

Info

Publication number
BE829887A
BE829887A BE1006709A BE1006709A BE829887A BE 829887 A BE829887 A BE 829887A BE 1006709 A BE1006709 A BE 1006709A BE 1006709 A BE1006709 A BE 1006709A BE 829887 A BE829887 A BE 829887A
Authority
BE
Belgium
Prior art keywords
thiomethylergolines
Prior art date
Application number
BE1006709A
Other languages
English (en)
French (fr)
Inventor
E C Kornfeld
N J Bach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE829887A publication Critical patent/BE829887A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE1006709A 1974-06-06 1975-06-05 8-thiomethylergolines BE829887A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US477136A US3901894A (en) 1974-06-06 1974-06-06 8-thiomethylergolines

Publications (1)

Publication Number Publication Date
BE829887A true BE829887A (fr) 1975-12-05

Family

ID=23894677

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1006709A BE829887A (fr) 1974-06-06 1975-06-05 8-thiomethylergolines

Country Status (27)

Country Link
US (1) US3901894A (xx)
JP (1) JPS582946B2 (xx)
AR (1) AR210736A1 (xx)
AT (1) AT344333B (xx)
AU (1) AU507574B2 (xx)
BE (1) BE829887A (xx)
BG (1) BG24812A3 (xx)
CA (1) CA1071623A (xx)
CH (1) CH617196A5 (xx)
CS (1) CS199591B2 (xx)
DD (1) DD120438A5 (xx)
DE (1) DE2524575A1 (xx)
DK (1) DK144160C (xx)
ES (1) ES438313A1 (xx)
FR (1) FR2273542A1 (xx)
GB (1) GB1505296A (xx)
HU (1) HU173590B (xx)
IE (1) IE41474B1 (xx)
IL (1) IL47424A (xx)
NL (1) NL180911C (xx)
PH (1) PH10992A (xx)
PL (1) PL95738B1 (xx)
RO (1) RO77543A (xx)
SE (1) SE420095B (xx)
SU (1) SU613724A3 (xx)
YU (1) YU145575A (xx)
ZA (1) ZA753638B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (it) * 1977-07-05 1988-03-31 Simes Derivati di ergoline-2-tioeteri e loro solfossidi
US4180582A (en) * 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (de) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische zubereitungen mit zytostatischer wirkung
FR2526797A1 (fr) * 1982-05-12 1983-11-18 Roussel Uclaf Nouveaux derives de l'acide 9-oxalysergique, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
CH649998A5 (de) * 1982-08-09 1985-06-28 Sandoz Ag Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (fr) * 1985-11-13 1988-09-02 Roussel Uclaf Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
JP3996897B2 (ja) * 2001-06-08 2007-10-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス ソマトスタチン−ドーパミンキメラ類似体
EP1485382B1 (en) * 2002-03-15 2008-11-19 Antibioticos S.p.A. Process for the synthesis of pergolide
EP2914276A4 (en) 2012-11-01 2016-07-13 Ipsen Pharma Sas SOMATOSTATIN ANALOGA AND DIMERE OUT
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
BR112017003570A2 (pt) 2014-09-25 2017-12-05 Boehringer Ingelheim Vetmedica Gmbh tratamento de combinação de inibidores de sglt2 e agonistas de dopamina para prevenir distúrbios metabólicos em animais equinos
US20190374534A1 (en) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (xx) * 1967-03-16 1968-07-15
DE1935556A1 (de) * 1969-07-12 1971-01-21 Hoechst Ag Verfahren zur Herstellung von Lysergol
JPS5012398A (xx) * 1973-06-08 1975-02-07

Also Published As

Publication number Publication date
RO77543A (ro) 1982-02-26
FR2273542A1 (fr) 1976-01-02
SU613724A3 (ru) 1978-06-30
AU8182775A (en) 1976-12-09
SE7506327L (sv) 1975-12-08
DD120438A5 (xx) 1976-06-12
JPS582946B2 (ja) 1983-01-19
ATA427975A (de) 1977-11-15
NL180911C (nl) 1987-05-18
GB1505296A (en) 1978-03-30
AU507574B2 (en) 1980-02-21
PH10992A (en) 1977-10-20
FR2273542B1 (xx) 1978-10-06
ZA753638B (en) 1977-01-26
NL7506584A (nl) 1975-12-09
HU173590B (hu) 1979-06-28
JPS50160300A (xx) 1975-12-25
CS199591B2 (en) 1980-07-31
CH617196A5 (xx) 1980-05-14
IL47424A0 (en) 1975-08-31
DK249975A (da) 1975-12-07
AT344333B (de) 1978-07-10
YU145575A (en) 1982-02-28
ES438313A1 (es) 1977-05-16
DK144160B (da) 1981-12-28
CA1071623A (en) 1980-02-12
AR210736A1 (es) 1977-09-15
US3901894A (en) 1975-08-26
DK144160C (da) 1982-06-07
NL180911B (nl) 1986-12-16
DE2524575A1 (de) 1975-12-18
IE41474B1 (en) 1980-01-16
PL95738B1 (pl) 1977-11-30
BG24812A3 (en) 1978-05-12
IL47424A (en) 1979-11-30
IE41474L (en) 1975-12-06
SE420095B (sv) 1981-09-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19910630