BE829887A - 8-THIOMETHYLERGOLINES - Google Patents

8-THIOMETHYLERGOLINES

Info

Publication number
BE829887A
BE829887A BE1006709A BE1006709A BE829887A BE 829887 A BE829887 A BE 829887A BE 1006709 A BE1006709 A BE 1006709A BE 1006709 A BE1006709 A BE 1006709A BE 829887 A BE829887 A BE 829887A
Authority
BE
Belgium
Prior art keywords
thiomethylergolines
Prior art date
Application number
BE1006709A
Other languages
French (fr)
Inventor
E C Kornfeld
N J Bach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE829887A publication Critical patent/BE829887A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
BE1006709A 1974-06-06 1975-06-05 8-THIOMETHYLERGOLINES BE829887A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US477136A US3901894A (en) 1974-06-06 1974-06-06 8-thiomethylergolines

Publications (1)

Publication Number Publication Date
BE829887A true BE829887A (en) 1975-12-05

Family

ID=23894677

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1006709A BE829887A (en) 1974-06-06 1975-06-05 8-THIOMETHYLERGOLINES

Country Status (27)

Country Link
US (1) US3901894A (en)
JP (1) JPS582946B2 (en)
AR (1) AR210736A1 (en)
AT (1) AT344333B (en)
AU (1) AU507574B2 (en)
BE (1) BE829887A (en)
BG (1) BG24812A3 (en)
CA (1) CA1071623A (en)
CH (1) CH617196A5 (en)
CS (1) CS199591B2 (en)
DD (1) DD120438A5 (en)
DE (1) DE2524575A1 (en)
DK (1) DK144160C (en)
ES (1) ES438313A1 (en)
FR (1) FR2273542A1 (en)
GB (1) GB1505296A (en)
HU (1) HU173590B (en)
IE (1) IE41474B1 (en)
IL (1) IL47424A (en)
NL (1) NL180911C (en)
PH (1) PH10992A (en)
PL (1) PL95738B1 (en)
RO (1) RO77543A (en)
SE (1) SE420095B (en)
SU (1) SU613724A3 (en)
YU (1) YU145575A (en)
ZA (1) ZA753638B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (en) * 1977-07-05 1988-03-31 Simes ERGOLINE-2-THIOETHERS AND THEIR SULPHOXIDES DERIVATIVES
US4180582A (en) * 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (en) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen PHARMACEUTICAL PREPARATIONS WITH A CYTOSTATIC EFFECT
FR2526797A1 (en) * 1982-05-12 1983-11-18 Roussel Uclaf NOVEL 9-OXALYSERGIC ACID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME
CH649998A5 (en) * 1982-08-09 1985-06-28 Sandoz Ag ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (en) * 1985-11-13 1988-09-02 Roussel Uclaf USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
ES2483722T3 (en) * 2001-06-08 2014-08-07 Ipsen Pharma Chimeric somatostatin-dopamine analogs
US7019140B2 (en) * 2002-03-15 2006-03-28 Antibioticos S.P.A. Process for the synthesis of pergolide
CN104768565B (en) 2012-11-01 2017-04-26 益普生制药股份有限公司 Somatostatin analogs and dimers thereof
TWI523863B (en) 2012-11-01 2016-03-01 艾普森藥品公司 Somatostatin-dopamine chimeric analogs
US20190374534A1 (en) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507248A (en) * 1967-03-16 1971-05-15 Spofa Vereinigte Pharma Werke Process for the preparation of D-6-methylergolin (I) ylacetic acid
DE1935556A1 (en) * 1969-07-12 1971-01-21 Hoechst Ag Process for the production of lysergol
JPS5012398A (en) * 1973-06-08 1975-02-07

Also Published As

Publication number Publication date
FR2273542B1 (en) 1978-10-06
HU173590B (en) 1979-06-28
SE420095B (en) 1981-09-14
DK144160C (en) 1982-06-07
GB1505296A (en) 1978-03-30
CA1071623A (en) 1980-02-12
DK249975A (en) 1975-12-07
YU145575A (en) 1982-02-28
JPS582946B2 (en) 1983-01-19
NL180911B (en) 1986-12-16
IE41474L (en) 1975-12-06
AR210736A1 (en) 1977-09-15
ES438313A1 (en) 1977-05-16
NL7506584A (en) 1975-12-09
FR2273542A1 (en) 1976-01-02
US3901894A (en) 1975-08-26
PH10992A (en) 1977-10-20
IL47424A (en) 1979-11-30
CH617196A5 (en) 1980-05-14
SE7506327L (en) 1975-12-08
IE41474B1 (en) 1980-01-16
NL180911C (en) 1987-05-18
SU613724A3 (en) 1978-06-30
AU507574B2 (en) 1980-02-21
DE2524575A1 (en) 1975-12-18
CS199591B2 (en) 1980-07-31
RO77543A (en) 1982-02-26
AT344333B (en) 1978-07-10
DD120438A5 (en) 1976-06-12
ATA427975A (en) 1977-11-15
AU8182775A (en) 1976-12-09
BG24812A3 (en) 1978-05-12
IL47424A0 (en) 1975-08-31
DK144160B (en) 1981-12-28
PL95738B1 (en) 1977-11-30
JPS50160300A (en) 1975-12-25
ZA753638B (en) 1977-01-26

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19910630