AT344333B - METHOD FOR PRODUCING NEW 8-THIOMETHYLERGOLINES - Google Patents

METHOD FOR PRODUCING NEW 8-THIOMETHYLERGOLINES

Info

Publication number
AT344333B
AT344333B AT427975A AT427975A AT344333B AT 344333 B AT344333 B AT 344333B AT 427975 A AT427975 A AT 427975A AT 427975 A AT427975 A AT 427975A AT 344333 B AT344333 B AT 344333B
Authority
AT
Austria
Prior art keywords
thiomethylergolines
producing new
producing
new
Prior art date
Application number
AT427975A
Other languages
German (de)
Other versions
ATA427975A (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ATA427975A publication Critical patent/ATA427975A/en
Application granted granted Critical
Publication of AT344333B publication Critical patent/AT344333B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT427975A 1974-06-06 1975-06-05 METHOD FOR PRODUCING NEW 8-THIOMETHYLERGOLINES AT344333B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US477136A US3901894A (en) 1974-06-06 1974-06-06 8-thiomethylergolines

Publications (2)

Publication Number Publication Date
ATA427975A ATA427975A (en) 1977-11-15
AT344333B true AT344333B (en) 1978-07-10

Family

ID=23894677

Family Applications (1)

Application Number Title Priority Date Filing Date
AT427975A AT344333B (en) 1974-06-06 1975-06-05 METHOD FOR PRODUCING NEW 8-THIOMETHYLERGOLINES

Country Status (27)

Country Link
US (1) US3901894A (en)
JP (1) JPS582946B2 (en)
AR (1) AR210736A1 (en)
AT (1) AT344333B (en)
AU (1) AU507574B2 (en)
BE (1) BE829887A (en)
BG (1) BG24812A3 (en)
CA (1) CA1071623A (en)
CH (1) CH617196A5 (en)
CS (1) CS199591B2 (en)
DD (1) DD120438A5 (en)
DE (1) DE2524575A1 (en)
DK (1) DK144160C (en)
ES (1) ES438313A1 (en)
FR (1) FR2273542A1 (en)
GB (1) GB1505296A (en)
HU (1) HU173590B (en)
IE (1) IE41474B1 (en)
IL (1) IL47424A (en)
NL (1) NL180911C (en)
PH (1) PH10992A (en)
PL (1) PL95738B1 (en)
RO (1) RO77543A (en)
SE (1) SE420095B (en)
SU (1) SU613724A3 (en)
YU (1) YU145575A (en)
ZA (1) ZA753638B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4147789A (en) * 1974-03-14 1979-04-03 Sandoz Ltd. 6-Methyl-8-thiomethyl-ergolene derivatives
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
JPS5283894A (en) * 1976-01-01 1977-07-13 Lilly Co Eli 88thiomethyl ergoline
GB1549829A (en) * 1976-05-26 1979-08-08 Farmaceutici Italia 10'-methoxy-1',6'-dimethylergoline-8'-beta-methyl-amino(or thio)-pyrazines
IT1192260B (en) * 1977-07-05 1988-03-31 Simes ERGOLINE-2-THIOETHERS AND THEIR SULPHOXIDES DERIVATIVES
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4180582A (en) * 1978-02-08 1979-12-25 Eli Lilly And Company 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
US4202979A (en) * 1979-01-11 1980-05-13 Eli Lilly And Company 6-Ethyl(or allyl)-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4246265A (en) * 1979-10-01 1981-01-20 Eli Lilly And Company 6-n-Propyl-8α-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity
DE3216870A1 (en) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen PHARMACEUTICAL PREPARATIONS WITH A CYTOSTATIC EFFECT
FR2526797A1 (en) * 1982-05-12 1983-11-18 Roussel Uclaf NOVEL 9-OXALYSERGIC ACID DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME
CH649998A5 (en) * 1982-08-09 1985-06-28 Sandoz Ag ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE.
GB8427536D0 (en) * 1984-10-31 1984-12-05 Lilly Industries Ltd Ergoline derivatives
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
FR2589734B1 (en) * 1985-11-13 1988-09-02 Roussel Uclaf USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
CA2449634C (en) * 2001-06-08 2011-08-02 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R Somatostatin-dopamine chimeric analogs
EP1485382B1 (en) * 2002-03-15 2008-11-19 Antibioticos S.p.A. Process for the synthesis of pergolide
JP2016503402A (en) 2012-11-01 2016-02-04 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエＩｐｓｅｎ Ｐｈａｒｍａ Ｓ．Ａ．Ｓ． Somatostatin analogs and dimers thereof
TWI523863B (en) 2012-11-01 2016-03-01 艾普森藥品公司 Somatostatin-dopamine chimeric analogs
WO2019234069A1 (en) 2018-06-08 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Liquid pharmaceutical compositions comprising pergolide

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (en) * 1967-03-16 1968-07-15
DE1935556A1 (en) * 1969-07-12 1971-01-21 Hoechst Ag Process for the production of lysergol
JPS5012398A (en) * 1973-06-08 1975-02-07

Also Published As

Publication number Publication date
BE829887A (en) 1975-12-05
SE7506327L (en) 1975-12-08
DK144160C (en) 1982-06-07
SU613724A3 (en) 1978-06-30
DK249975A (en) 1975-12-07
FR2273542A1 (en) 1976-01-02
PH10992A (en) 1977-10-20
JPS50160300A (en) 1975-12-25
JPS582946B2 (en) 1983-01-19
GB1505296A (en) 1978-03-30
PL95738B1 (en) 1977-11-30
AU507574B2 (en) 1980-02-21
DE2524575A1 (en) 1975-12-18
IL47424A (en) 1979-11-30
IE41474L (en) 1975-12-06
AU8182775A (en) 1976-12-09
NL7506584A (en) 1975-12-09
ES438313A1 (en) 1977-05-16
RO77543A (en) 1982-02-26
NL180911B (en) 1986-12-16
FR2273542B1 (en) 1978-10-06
BG24812A3 (en) 1978-05-12
CS199591B2 (en) 1980-07-31
IL47424A0 (en) 1975-08-31
AR210736A1 (en) 1977-09-15
CH617196A5 (en) 1980-05-14
DD120438A5 (en) 1976-06-12
SE420095B (en) 1981-09-14
CA1071623A (en) 1980-02-12
US3901894A (en) 1975-08-26
ZA753638B (en) 1977-01-26
ATA427975A (en) 1977-11-15
NL180911C (en) 1987-05-18
DK144160B (en) 1981-12-28
IE41474B1 (en) 1980-01-16
HU173590B (en) 1979-06-28
YU145575A (en) 1982-02-28

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee