CN104321429A - 经修饰的级联核糖核蛋白及其用途 - Google Patents

经修饰的级联核糖核蛋白及其用途 Download PDF

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CN104321429A
CN104321429A CN201280071058.4A CN201280071058A CN104321429A CN 104321429 A CN104321429 A CN 104321429A CN 201280071058 A CN201280071058 A CN 201280071058A CN 104321429 A CN104321429 A CN 104321429A
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sequence
nucleic acid
cascade
subunit
amino acid
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斯坦·乔翰·约瑟夫·布朗兹
约翰·万德奥斯特
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Caribou Biosciences Inc
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Wageningen Universiteit
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    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
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CN201280071058.4A 2011-12-30 2012-12-21 经修饰的级联核糖核蛋白及其用途 Pending CN104321429A (zh)

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GB1122458.1 2011-12-30
GB201122458A GB201122458D0 (en) 2011-12-30 2011-12-30 Modified cascade ribonucleoproteins and uses thereof
PCT/EP2012/076674 WO2013098244A1 (en) 2011-12-30 2012-12-21 Modified cascade ribonucleoproteins and uses thereof

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Cited By (11)

* Cited by examiner, † Cited by third party
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CN105331627A (zh) * 2015-09-30 2016-02-17 华中农业大学 一种利用内源CRISPR-Cas系统进行原核生物基因组编辑的方法
CN107922918A (zh) * 2015-06-15 2018-04-17 北卡罗来纳州立大学 用于有效递送核酸和基于rna的抗微生物剂的方法和组合物
CN108271385A (zh) * 2015-09-09 2018-07-10 国立大学法人神户大学 用于特异性转变靶向dna序列的核酸碱基的基因组序列的修饰方法、及其使用的分子复合体
CN111304230A (zh) * 2013-07-26 2020-06-19 哈佛大学校长及研究员协会 基因组工程
CN111849978A (zh) * 2020-06-11 2020-10-30 中山大学 一种基于Type I-F CRISPR/Cas的染色质成像方法和染色质成像系统
CN111979240A (zh) * 2020-06-11 2020-11-24 中山大学 一种基于Type I-F CRISPR/Cas的基因表达调控方法和调控系统
CN112272704A (zh) * 2018-06-13 2021-01-26 卡里布生物科学公司 改造的cascade组分和cascade复合体
CN112533627A (zh) * 2018-03-27 2021-03-19 G+Flas 生命科学公司 序列特异性体内细胞靶向
CN115851664A (zh) * 2022-09-19 2023-03-28 中国药科大学 一种I-B型CRISPR-Cascade-Cas3基因编辑系统及应用
CN117384867A (zh) * 2022-09-16 2024-01-12 北京普译生物科技有限公司 一种经修饰的Cas3移位酶及其应用
WO2025156264A1 (zh) * 2024-01-26 2025-07-31 中国科学院微生物研究所 一种精简的I型CRISPR-Cas效应复合物及其应用

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US7790756B2 (en) 2006-10-11 2010-09-07 Deciphera Pharmaceuticals, Llc Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases
CN103038338B (zh) 2010-05-10 2017-03-08 加利福尼亚大学董事会 核糖核酸内切酶组合物及其使用方法
BR112013024337A2 (pt) 2011-03-23 2017-09-26 Du Pont locus de traço transgênico complexo em uma planta, planta ou semente, método para produzir em uma planta um locus de traço transgênico complexo e construto de expressão
EP3613852A3 (en) 2011-07-22 2020-04-22 President and Fellows of Harvard College Evaluation and improvement of nuclease cleavage specificity
JP2014531908A (ja) 2011-10-14 2014-12-04 プレジデント アンド フェローズ オブ ハーバード カレッジ 構造アッセンブリによる配列決定
JP2015500648A (ja) 2011-12-16 2015-01-08 ターゲットジーン バイオテクノロジーズ リミテッド 所定の標的核酸配列を修飾するための組成物及び方法
ES2991004T3 (es) 2011-12-22 2024-12-02 Harvard College Métodos para la detección de analitos
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