ATE347593T1 - Zielgerichtete chromosomale mutagenese mit zinkfingernukleasen - Google Patents

Zielgerichtete chromosomale mutagenese mit zinkfingernukleasen

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Publication number
ATE347593T1
ATE347593T1 AT03746527T AT03746527T ATE347593T1 AT E347593 T1 ATE347593 T1 AT E347593T1 AT 03746527 T AT03746527 T AT 03746527T AT 03746527 T AT03746527 T AT 03746527T AT E347593 T1 ATE347593 T1 AT E347593T1
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AT
Austria
Prior art keywords
genetic material
present
provides
targeted
mutagenesis
Prior art date
Application number
AT03746527T
Other languages
English (en)
Inventor
Dana Carroll
Marina Bibikova
Gary N Drews
Kent Gregory Golic
Mary M Golic
Original Assignee
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of ATE347593T1 publication Critical patent/ATE347593T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
    • A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
    • A01K67/0337—Genetically modified Arthropods
    • A01K67/0339—Genetically modified insects, e.g. Drosophila melanogaster, medfly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
AT03746527T 2002-01-23 2003-01-22 Zielgerichtete chromosomale mutagenese mit zinkfingernukleasen ATE347593T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35103502P 2002-01-23 2002-01-23

Publications (1)

Publication Number Publication Date
ATE347593T1 true ATE347593T1 (de) 2006-12-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
AT03746527T ATE347593T1 (de) 2002-01-23 2003-01-22 Zielgerichtete chromosomale mutagenese mit zinkfingernukleasen

Country Status (10)

Country Link
US (4) US8106255B2 (de)
EP (1) EP1476547B1 (de)
JP (2) JP4968498B2 (de)
CN (1) CN100575485C (de)
AT (1) ATE347593T1 (de)
AU (1) AU2003251286B2 (de)
BR (2) BR0307383A (de)
CA (1) CA2474486C (de)
DE (1) DE60310202T2 (de)
WO (1) WO2003087341A2 (de)

Families Citing this family (408)

* Cited by examiner, † Cited by third party
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DE60310202D1 (de) 2007-01-18
AU2003251286B2 (en) 2007-08-16
CA2474486C (en) 2013-05-14
US20160076045A1 (en) 2016-03-17
WO2003087341A2 (en) 2003-10-23
CN1622993A (zh) 2005-06-01
EP1476547A4 (de) 2005-08-17
CN100575485C (zh) 2009-12-30
US20110014601A2 (en) 2011-01-20
US20120219959A1 (en) 2012-08-30
JP2009195256A (ja) 2009-09-03
CA2474486A1 (en) 2003-10-23
EP1476547B1 (de) 2006-12-06
US20050208489A1 (en) 2005-09-22
BRPI0307383B1 (pt) 2019-12-31
JP4968498B2 (ja) 2012-07-04
AU2003251286A1 (en) 2003-10-27
US20200231979A1 (en) 2020-07-23
BR0307383A (pt) 2005-04-26
US9145565B2 (en) 2015-09-29
JP2005519631A (ja) 2005-07-07
US8106255B2 (en) 2012-01-31

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