CN102481312B - 合成的吡喃葡萄糖脂佐剂 - Google Patents
合成的吡喃葡萄糖脂佐剂 Download PDFInfo
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Abstract
Description
Claims (11)
Priority Applications (1)
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CN201510353412.8A CN105131051B (zh) | 2009-06-05 | 2010-06-04 | 合成的吡喃葡萄糖脂佐剂 |
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US18470309P | 2009-06-05 | 2009-06-05 | |
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PCT/US2010/037466 WO2010141861A1 (en) | 2009-06-05 | 2010-06-04 | Synthetic glucopyranosyl lipid adjuvants |
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CN102481312A CN102481312A (zh) | 2012-05-30 |
CN102481312B true CN102481312B (zh) | 2015-07-15 |
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CN201080034214.0A Active CN102481312B (zh) | 2009-06-05 | 2010-06-04 | 合成的吡喃葡萄糖脂佐剂 |
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EP (2) | EP2437753B1 (zh) |
JP (3) | JP5830015B2 (zh) |
CN (2) | CN105131051B (zh) |
AU (1) | AU2010256461B2 (zh) |
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SM (1) | SMT201600437B (zh) |
TW (2) | TWI549688B (zh) |
WO (1) | WO2010141861A1 (zh) |
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BRPI0923225A2 (pt) | 2008-12-02 | 2016-10-04 | Chiralgen Ltd | metodo para sintese de acidos nucleicos modificados no atomo de fosforo |
EP2437753B1 (en) | 2009-06-05 | 2016-08-31 | Infectious Disease Research Institute | Synthetic glucopyranosyl lipid adjuvants and vaccine compositions containing them |
MX342945B (es) | 2009-07-06 | 2016-10-18 | Ontorii Inc * | Profármacos de ácido nucleico novedosos y métodos de uso de los mismos. |
BR112012022939A2 (pt) | 2010-03-11 | 2016-08-02 | Immune Design Corp | composição farmacêutica para uso em um método de imunização de um indivíduo em necessidade do mesmo contra um vírus influenza |
JP5868324B2 (ja) | 2010-09-24 | 2016-02-24 | 株式会社Wave Life Sciences Japan | 不斉補助基 |
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EP2780350B1 (en) * | 2011-11-18 | 2019-03-06 | Variation Biotechnologies Inc. | Synthetic derivatives of mpl and uses thereof |
ES2894724T3 (es) | 2011-12-02 | 2022-02-15 | Rhode Island Hospital | Vacuna contra la malaria falciparum |
US11510875B2 (en) | 2012-02-07 | 2022-11-29 | Access To Advanced Health Institute | Adjuvant formulations comprising TLR4 agonists and methods of using the same |
JP5650780B2 (ja) | 2012-04-04 | 2015-01-07 | 日東電工株式会社 | ワクチン組成物 |
EP3388835B1 (en) | 2012-05-16 | 2020-04-01 | Immune Design Corp. | Vaccines for hsv-2 |
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CN104684893B (zh) | 2012-07-13 | 2016-10-26 | 日本波涛生命科学公司 | 不对称辅助基团 |
RU2677639C2 (ru) * | 2012-07-13 | 2019-01-18 | Шин Ниппон Биомедикал Лэбораториз, Лтд. | Хиральный адъювант нуклеиновой кислоты |
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