CA2869945C - Modulators of atp-binding cassette transporters - Google Patents

Modulators of atp-binding cassette transporters Download PDF

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Publication number
CA2869945C
CA2869945C CA2869945A CA2869945A CA2869945C CA 2869945 C CA2869945 C CA 2869945C CA 2869945 A CA2869945 A CA 2869945A CA 2869945 A CA2869945 A CA 2869945A CA 2869945 C CA2869945 C CA 2869945C
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Prior art keywords
optionally substituted
independently
aliphatic
ring
cycloaliphatic
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CA2869945A
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English (en)
French (fr)
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CA2869945A1 (en
Inventor
Sara S. Hadida Ruah
Peter D.J. Grootenhuis
Fredrick Van Goor
Jinglan Zhou
Brian Bear
Mark T. Miller
Jason Mccartney
Mehdi Michel Jamel Numa
Xiaoqing Yang
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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CA2869945A 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters Active CA2869945C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79045906P 2006-04-07 2006-04-07
US60/790,459 2006-04-07
CA2648719A CA2648719C (en) 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters

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CA2648719A Division CA2648719C (en) 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters

Publications (2)

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CA2869945A1 CA2869945A1 (en) 2007-10-18
CA2869945C true CA2869945C (en) 2018-01-23

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CA2869945A Active CA2869945C (en) 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters
CA2648719A Active CA2648719C (en) 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters

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US (9) US7776905B2 (enExample)
EP (5) EP2007756B1 (enExample)
JP (3) JP5420395B2 (enExample)
CN (2) CN103254177A (enExample)
AU (1) AU2007235260B2 (enExample)
BR (1) BRPI0710965B8 (enExample)
CA (2) CA2869945C (enExample)
CY (3) CY1116979T1 (enExample)
DK (3) DK3091011T3 (enExample)
ES (4) ES2659364T3 (enExample)
HU (4) HUE036165T2 (enExample)
IL (1) IL194576A (enExample)
IN (1) IN2014KN02423A (enExample)
LT (1) LT3091011T (enExample)
MX (1) MX2008012945A (enExample)
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