MX2008012945A - Moduladores de transportadores de cartucho de union a adenosina-trifosfato celular (atp). - Google Patents

Moduladores de transportadores de cartucho de union a adenosina-trifosfato celular (atp).

Info

Publication number
MX2008012945A
MX2008012945A MX2008012945A MX2008012945A MX2008012945A MX 2008012945 A MX2008012945 A MX 2008012945A MX 2008012945 A MX2008012945 A MX 2008012945A MX 2008012945 A MX2008012945 A MX 2008012945A MX 2008012945 A MX2008012945 A MX 2008012945A
Authority
MX
Mexico
Prior art keywords
optionally substituted
independently
mmol
carbonyl
aliphatic
Prior art date
Application number
MX2008012945A
Other languages
English (en)
Spanish (es)
Inventor
Brian Bear
Peter D J Grootenhuis
Sara S Hadida Ruah
Frederick Van Goor
Jinglan Zhou
Mark T Miller
Jason Mccartney
Mehdi Michel Jamel Numa
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of MX2008012945A publication Critical patent/MX2008012945A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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  • Pharmacology & Pharmacy (AREA)
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  • Urology & Nephrology (AREA)
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MX2008012945A 2006-04-07 2007-04-09 Moduladores de transportadores de cartucho de union a adenosina-trifosfato celular (atp). MX2008012945A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79045906P 2006-04-07 2006-04-07
PCT/US2007/008975 WO2007117715A2 (en) 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters

Publications (1)

Publication Number Publication Date
MX2008012945A true MX2008012945A (es) 2009-01-15

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MX2008012945A MX2008012945A (es) 2006-04-07 2007-04-09 Moduladores de transportadores de cartucho de union a adenosina-trifosfato celular (atp).

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US (9) US7776905B2 (enExample)
EP (5) EP2674428B1 (enExample)
JP (3) JP5420395B2 (enExample)
CN (2) CN101460489A (enExample)
AU (1) AU2007235260B2 (enExample)
BR (1) BRPI0710965B8 (enExample)
CA (2) CA2648719C (enExample)
CY (3) CY1116979T1 (enExample)
DK (3) DK3091011T3 (enExample)
ES (4) ES2580803T3 (enExample)
HU (4) HUE026145T2 (enExample)
IL (1) IL194576A (enExample)
IN (1) IN2014KN02423A (enExample)
LT (1) LT3091011T (enExample)
MX (1) MX2008012945A (enExample)
NZ (3) NZ571803A (enExample)
PL (4) PL3091011T3 (enExample)
PT (3) PT2007756E (enExample)
RU (1) RU2451018C2 (enExample)
SI (4) SI3327016T1 (enExample)
WO (1) WO2007117715A2 (enExample)
ZA (1) ZA200809290B (enExample)

Families Citing this family (114)

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