PL3091011T3 - Modulatory transporterów posiadających kasetę wiążącą ATP - Google Patents

Modulatory transporterów posiadających kasetę wiążącą ATP

Info

Publication number
PL3091011T3
PL3091011T3 PL16155334T PL16155334T PL3091011T3 PL 3091011 T3 PL3091011 T3 PL 3091011T3 PL 16155334 T PL16155334 T PL 16155334T PL 16155334 T PL16155334 T PL 16155334T PL 3091011 T3 PL3091011 T3 PL 3091011T3
Authority
PL
Poland
Prior art keywords
atp
modulators
binding cassette
cassette transporters
transporters
Prior art date
Application number
PL16155334T
Other languages
English (en)
Inventor
Sara S. Hadida Ruah
Peter D.J. Grootenhuis
Fredrick Van Goor
Jinglan Zhou
Brian Bear
Mark T. Miller
Jason Mccartney
Mehdi Michel Jamel Numa
Xiaoqing Yang
Original Assignee
Vertex Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Incorporated filed Critical Vertex Pharmaceuticals Incorporated
Publication of PL3091011T3 publication Critical patent/PL3091011T3/pl

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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • C—CHEMISTRY; METALLURGY
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    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
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    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • G—PHYSICS
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PL16155334T 2006-04-07 2007-04-09 Modulatory transporterów posiadających kasetę wiążącą ATP PL3091011T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79045906P 2006-04-07 2006-04-07
EP16155334.2A EP3091011B1 (en) 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters
EP13167785.8A EP2674428B1 (en) 2006-04-07 2007-04-09 Modulators of ATP-binding cassette transporters
EP07755298.2A EP2007756B1 (en) 2006-04-07 2007-04-09 Modulators of atp-binding cassette transporters

Publications (1)

Publication Number Publication Date
PL3091011T3 true PL3091011T3 (pl) 2018-06-29

Family

ID=38477342

Family Applications (4)

Application Number Title Priority Date Filing Date
PL16155334T PL3091011T3 (pl) 2006-04-07 2007-04-09 Modulatory transporterów posiadających kasetę wiążącą ATP
PL13167785T PL2674428T3 (pl) 2006-04-07 2007-04-09 Modulatory transporterów z kasetą wiążącą ATP
PL07755298T PL2007756T3 (pl) 2006-04-07 2007-04-09 Modulatory transporterów posiadających kasetę wiążącą ATP
PL17209175T PL3327016T3 (pl) 2006-04-07 2007-04-09 Wytwarzanie modulatorów transporterów posiadających kasetę wiążącą ATP

Family Applications After (3)

Application Number Title Priority Date Filing Date
PL13167785T PL2674428T3 (pl) 2006-04-07 2007-04-09 Modulatory transporterów z kasetą wiążącą ATP
PL07755298T PL2007756T3 (pl) 2006-04-07 2007-04-09 Modulatory transporterów posiadających kasetę wiążącą ATP
PL17209175T PL3327016T3 (pl) 2006-04-07 2007-04-09 Wytwarzanie modulatorów transporterów posiadających kasetę wiążącą ATP

Country Status (22)

Country Link
US (9) US7776905B2 (pl)
EP (5) EP3327016B1 (pl)
JP (3) JP5420395B2 (pl)
CN (2) CN101460489A (pl)
AU (1) AU2007235260B2 (pl)
BR (1) BRPI0710965B8 (pl)
CA (2) CA2648719C (pl)
CY (3) CY1116979T1 (pl)
DK (3) DK3091011T3 (pl)
ES (4) ES2659364T3 (pl)
HU (4) HUE055205T2 (pl)
IL (1) IL194576A (pl)
IN (1) IN2014KN02423A (pl)
LT (1) LT3091011T (pl)
MX (1) MX2008012945A (pl)
NZ (3) NZ596889A (pl)
PL (4) PL3091011T3 (pl)
PT (3) PT3091011T (pl)
RU (1) RU2451018C2 (pl)
SI (4) SI3091011T1 (pl)
WO (1) WO2007117715A2 (pl)
ZA (1) ZA200809290B (pl)

Families Citing this family (106)

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Publication number Priority date Publication date Assignee Title
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
EP1664006A2 (en) 2003-09-06 2006-06-07 Vertex Pharmaceuticals Incorporated Modulators of atp-binding cassette transporters
CA2545719A1 (en) * 2003-11-14 2005-06-02 Vertex Pharmaceuticals Incorporated Thiazoles and oxazoles useful as modulators of atp-binding cassette transporters
US7977322B2 (en) 2004-08-20 2011-07-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-binding cassette transporters
AU2005210474B2 (en) * 2004-01-30 2011-07-07 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding cassette transporters
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US20070244159A1 (en) 2007-10-18
US8912199B2 (en) 2014-12-16
DK3091011T3 (en) 2018-02-26
SI3327016T1 (sl) 2021-09-30
CA2648719C (en) 2015-02-24
LT3091011T (lt) 2018-04-10
RU2451018C2 (ru) 2012-05-20
EP2674428A1 (en) 2013-12-18
PT2007756E (pt) 2015-11-02
BRPI0710965B1 (pt) 2020-08-18
US20160332997A1 (en) 2016-11-17
HUE055205T2 (hu) 2021-11-29
JP5420395B2 (ja) 2014-02-19
EP2007756A2 (en) 2008-12-31
SI3091011T1 (en) 2018-06-29
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IN2014KN02423A (pl) 2015-05-01
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US7776905B2 (en) 2010-08-17
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EP2007756B1 (en) 2015-08-26
ES2882684T3 (es) 2021-12-02
JP5827297B2 (ja) 2015-12-02
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IL194576A (en) 2016-12-29
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AU2007235260A1 (en) 2007-10-18
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US20140057906A1 (en) 2014-02-27
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US20220411410A1 (en) 2022-12-29

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