PL2081937T3 - Triazolopirydazynowe modulatory kinaz białkowych - Google Patents

Triazolopirydazynowe modulatory kinaz białkowych

Info

Publication number
PL2081937T3
PL2081937T3 PL07854193T PL07854193T PL2081937T3 PL 2081937 T3 PL2081937 T3 PL 2081937T3 PL 07854193 T PL07854193 T PL 07854193T PL 07854193 T PL07854193 T PL 07854193T PL 2081937 T3 PL2081937 T3 PL 2081937T3
Authority
PL
Poland
Prior art keywords
triazolopyridazine
protein kinase
kinase modulators
modulators
protein
Prior art date
Application number
PL07854193T
Other languages
English (en)
Inventor
Christopher Ronald Smith
Pierre-Yves Bounaud
Elizabeth Anne Jefferson
Patrick S Lee
Eduardo Torres
Original Assignee
Sgx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sgx Pharmaceuticals Inc filed Critical Sgx Pharmaceuticals Inc
Publication of PL2081937T3 publication Critical patent/PL2081937T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL07854193T 2006-10-23 2007-10-18 Triazolopirydazynowe modulatory kinaz białkowych PL2081937T3 (pl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US86255206P 2006-10-23 2006-10-23
US87138406P 2006-12-21 2006-12-21
US91375207P 2007-04-24 2007-04-24
US95283307P 2007-07-30 2007-07-30
EP07854193A EP2081937B1 (en) 2006-10-23 2007-10-18 Triazolopyridazine protein kinase modulators
PCT/US2007/081832 WO2008051805A2 (en) 2006-10-23 2007-10-18 Triazolo-pyridazine protein kinase modulators

Publications (1)

Publication Number Publication Date
PL2081937T3 true PL2081937T3 (pl) 2013-01-31

Family

ID=39031065

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07854193T PL2081937T3 (pl) 2006-10-23 2007-10-18 Triazolopirydazynowe modulatory kinaz białkowych

Country Status (16)

Country Link
US (1) US8071581B2 (pl)
EP (1) EP2081937B1 (pl)
JP (1) JP2010507577A (pl)
KR (1) KR101083177B1 (pl)
AU (1) AU2007309237B2 (pl)
BR (1) BRPI0717317A2 (pl)
CA (1) CA2667453A1 (pl)
DK (1) DK2081937T3 (pl)
EA (1) EA016527B1 (pl)
ES (1) ES2393132T3 (pl)
MX (1) MX2009004060A (pl)
PE (1) PE20081256A1 (pl)
PL (1) PL2081937T3 (pl)
PT (1) PT2081937E (pl)
TW (1) TW200833692A (pl)
WO (1) WO2008051805A2 (pl)

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JP2014505088A (ja) 2011-02-10 2014-02-27 ノバルティス アーゲー Ｃ−ＭＥＴチロシンキナーゼ阻害剤としての［１，２，４］トリアゾロ［４，３−ｂ］ピリダジン化合物
US20140088114A1 (en) 2011-05-16 2014-03-27 OSI Pharmaceuticals ,LLC Fused bicyclic kinase inhibitors
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CN107082779A (zh) 2012-03-30 2017-08-22 理森制药股份公司 作为c‑met 蛋白激酶调节剂的新化合物
AU2013290444B2 (en) 2012-07-16 2018-04-26 Vertex Pharmaceuticals Incorporated Pharmaceutical compositions of (R)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide and administration thereof
CN103122000B (zh) * 2012-09-03 2013-12-25 中美冠科生物技术（太仓）有限公司 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂
TWI606045B (zh) 2012-10-16 2017-11-21 健生藥品公司 ＲＯＲγｔ之亞甲基聯結的喹啉基調節劑
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Also Published As

Publication number Publication date
EA200970402A1 (ru) 2009-10-30
CA2667453A1 (en) 2008-05-02
PT2081937E (pt) 2012-10-15
EP2081937A2 (en) 2009-07-29
TW200833692A (en) 2008-08-16
JP2010507577A (ja) 2010-03-11
WO2008051805A3 (en) 2008-07-10
AU2007309237B2 (en) 2012-03-22
EA016527B1 (ru) 2012-05-30
DK2081937T3 (da) 2012-10-01
EP2081937B1 (en) 2012-09-12
KR20090069303A (ko) 2009-06-30
ES2393132T3 (es) 2012-12-18
AU2007309237A1 (en) 2008-05-02
PE20081256A1 (es) 2008-10-13
BRPI0717317A2 (pt) 2013-10-22
MX2009004060A (es) 2009-06-19
US20100120739A1 (en) 2010-05-13
US8071581B2 (en) 2011-12-06
KR101083177B1 (ko) 2011-11-11
WO2008051805A2 (en) 2008-05-02

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