SI2081937T1 - Triazolopiridazinski modulatorji proteinskih kinaz - Google Patents

Triazolopiridazinski modulatorji proteinskih kinaz

Info

Publication number
SI2081937T1
SI2081937T1 SI200731024T SI200731024T SI2081937T1 SI 2081937 T1 SI2081937 T1 SI 2081937T1 SI 200731024 T SI200731024 T SI 200731024T SI 200731024 T SI200731024 T SI 200731024T SI 2081937 T1 SI2081937 T1 SI 2081937T1
Authority
SI
Slovenia
Prior art keywords
triazolopyridazine
protein kinase
kinase modulators
modulators
protein
Prior art date
Application number
SI200731024T
Other languages
English (en)
Inventor
Christopher Ronald Smith
Pierre-Yves Bounaud
Elizabeth Anne Jefferson
Patrick S Lee
Eduardo Torres
Original Assignee
Sgx Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sgx Pharmaceuticals Inc filed Critical Sgx Pharmaceuticals Inc
Priority claimed from PCT/US2007/081832 external-priority patent/WO2008051805A2/en
Publication of SI2081937T1 publication Critical patent/SI2081937T1/sl

Links

SI200731024T 2006-10-23 2007-10-18 Triazolopiridazinski modulatorji proteinskih kinaz SI2081937T1 (sl)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US86255206P 2006-10-23 2006-10-23
US87138406P 2006-12-21 2006-12-21
US91375207P 2007-04-24 2007-04-24
US95283307P 2007-07-30 2007-07-30
PCT/US2007/081832 WO2008051805A2 (en) 2006-10-23 2007-10-18 Triazolo-pyridazine protein kinase modulators
EP07854193A EP2081937B1 (en) 2006-10-23 2007-10-18 Triazolopyridazine protein kinase modulators

Publications (1)

Publication Number Publication Date
SI2081937T1 true SI2081937T1 (sl) 2012-11-30

Family

ID=41157042

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200731025T SI2084162T1 (sl) 2006-10-23 2007-10-18 Biciklični triazoli kot modulatroji proteinskih kinaz
SI200731024T SI2081937T1 (sl) 2006-10-23 2007-10-18 Triazolopiridazinski modulatorji proteinskih kinaz

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SI200731025T SI2084162T1 (sl) 2006-10-23 2007-10-18 Biciklični triazoli kot modulatroji proteinskih kinaz

Country Status (3)

Country Link
CN (2) CN101553490A (sl)
SI (2) SI2084162T1 (sl)
ZA (1) ZA200902170B (sl)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012019302B1 (pt) * 2010-02-03 2022-06-21 Incyte Holdings Corporation Imidazo[1,2-b] [1,2,4]triazinas como inibidores de c-met, composição que as compreende e métodos in vitro de inibir a atividade de c-met cinase, de inibir a via de sinalização da hgf/c-met cinase em uma célula e de inibir a atividade proliferativa de uma célula
AR085183A1 (es) * 2010-07-30 2013-09-18 Lilly Co Eli Compuesto 6-(1-metil-1h-pirazol-4-il)-3-(2-metil-2h-indazol-5-iltio)-[1,2,4]triazol[4,3-b]piridazina, composicion farmaceutica que lo comprende y uso para preparar un medicamento util para tratar cancer
CN103122000B (zh) * 2012-09-03 2013-12-25 中美冠科生物技术（太仓）有限公司 用作抗肿瘤药物的高选择性的c-Met激酶抑制剂
CN103664954A (zh) * 2012-09-17 2014-03-26 杨育新 一类治疗创伤性脑损伤疾病的化合物及其用途
CN103655576A (zh) * 2012-09-25 2014-03-26 杨子娇 一类治疗房角狭窄的化合物及其用途
JP6355719B2 (ja) * 2013-05-10 2018-07-11 ジエンス ハンセン ファーマセウティカル カンパニー リミテッド ［１，２，４］トリアゾール［４，３−ａ］ピリジン誘導体、その製造方法またはその医薬応用
GB201321745D0 (en) * 2013-12-09 2014-01-22 Ucb Pharma Sa Therapeutic agents
CN103804289B (zh) * 2014-01-16 2016-06-22 苏州泰利三佳纳米科技有限公司 6-甲氧基喹啉的合成方法
CN106687446B (zh) * 2014-07-18 2020-04-28 百济神州(北京)生物科技有限公司 作为t790m/wt-egfr的选择性和不可逆的激酶抑制剂的5-氨基-4-氨甲酰基-吡唑化合物及其用途
KR102665765B1 (ko) * 2015-07-20 2024-05-10 젠자임 코포레이션 콜로니 자극 인자-1 수용체(csf-1r) 저해제
WO2017049711A1 (zh) * 2015-09-24 2017-03-30 上海海聚生物科技有限公司 喹啉类衍生物、其药物组合物、制备方法及应用
BR112018006873A2 (pt) * 2015-10-05 2018-11-06 The Trustees Of Columbia University In The City Of New York ativadores do fluxo autofágico e fosfolipase d e depuração de agregados de proteína incluindo tau e tratamento de proteinopatias
EP3398951B1 (en) * 2015-12-31 2021-04-07 Shanghai Pharmaceuticals Holding Co., Ltd. Salt of quinolone compound, polymorphs thereof, preparation method therefor, composition, and applications
CN108864101B (zh) * 2017-05-12 2019-12-17 中国科学院上海药物研究所 氘代sgx523 及其用途
JP2024500919A (ja) 2020-12-23 2024-01-10 ジェンザイム・コーポレーション 重水素化コロニー刺激因子－１受容体（ｃｓｆ－１ｒ）阻害剤

Also Published As

Publication number Publication date
CN101553490A (zh) 2009-10-07
ZA200902170B (en) 2010-06-30
SI2084162T1 (sl) 2012-11-30
CN101558070A (zh) 2009-10-14

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