BRPI0807046A2 - Composto, composição farmacêutica, métodos de tratar um distúrbio, uma doença cardiovascular e um paciente que sofre de motilidade gastrointestinal reduzida ou disfuncional e, kit. - Google Patents

Composto, composição farmacêutica, métodos de tratar um distúrbio, uma doença cardiovascular e um paciente que sofre de motilidade gastrointestinal reduzida ou disfuncional e, kit.

Info

Publication number
BRPI0807046A2
BRPI0807046A2 BRPI0807046-6A BRPI0807046A BRPI0807046A2 BR PI0807046 A2 BRPI0807046 A2 BR PI0807046A2 BR PI0807046 A BRPI0807046 A BR PI0807046A BR PI0807046 A2 BRPI0807046 A2 BR PI0807046A2
Authority
BR
Brazil
Prior art keywords
disorder
kit
treating
compound
methods
Prior art date
Application number
BRPI0807046-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Hamid Hoveyda
Graeme Fraser
Sophia Beauchemin
Martin Brassard
David Drutz
Éric Marsault
Luc Ouellet
Mark L Peterson
Zhingang Wang
Kamel Benakli
Original Assignee
Tranzyme Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tranzyme Pharma Inc filed Critical Tranzyme Pharma Inc
Publication of BRPI0807046A2 publication Critical patent/BRPI0807046A2/pt

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
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    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Otolaryngology (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biophysics (AREA)
BRPI0807046-6A 2007-02-09 2008-02-08 Composto, composição farmacêutica, métodos de tratar um distúrbio, uma doença cardiovascular e um paciente que sofre de motilidade gastrointestinal reduzida ou disfuncional e, kit. BRPI0807046A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88916307P 2007-02-09 2007-02-09
PCT/US2008/001754 WO2008130464A1 (en) 2007-02-09 2008-02-08 Macrocyclic ghrelin receptor modulators and methods of using the same

Publications (1)

Publication Number Publication Date
BRPI0807046A2 true BRPI0807046A2 (pt) 2015-05-26

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Application Number Title Priority Date Filing Date
BRPI0807046-6A BRPI0807046A2 (pt) 2007-02-09 2008-02-08 Composto, composição farmacêutica, métodos de tratar um distúrbio, uma doença cardiovascular e um paciente que sofre de motilidade gastrointestinal reduzida ou disfuncional e, kit.

Country Status (12)

Country Link
US (3) US9371297B2 (enExample)
EP (2) EP2644618B1 (enExample)
JP (2) JP2010518090A (enExample)
KR (1) KR20090107088A (enExample)
CN (1) CN101657436A (enExample)
AU (1) AU2008241532A1 (enExample)
BR (1) BRPI0807046A2 (enExample)
CA (1) CA2677399C (enExample)
EA (1) EA200901077A1 (enExample)
ES (2) ES2604943T3 (enExample)
MX (1) MX2009008574A (enExample)
WO (1) WO2008130464A1 (enExample)

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US7491695B2 (en) * 2003-06-18 2009-02-17 Tranzyme Pharma Inc. Methods of using macrocyclic modulators of the ghrelin receptor
US20090198050A1 (en) * 2003-06-18 2009-08-06 Tranzyme Pharma Inc. Macrocyclic Modulators of the Ghrelin Receptor
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
US8921521B2 (en) 2003-06-18 2014-12-30 Ocera Therapeutics, Inc. Macrocyclic modulators of the Ghrelin receptor
US7476653B2 (en) * 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
US8088733B2 (en) * 2006-07-06 2012-01-03 Tranzyme Pharma Inc. Methods of using macrocyclic agonists of the ghrelin receptor for treatment of gastrointestinal motility disorders
EP2952522B1 (en) 2007-01-31 2019-10-30 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
CA2677813A1 (en) * 2007-02-13 2008-08-21 Helsinn Therapeutics (U.S.), Inc. Method of treating cell proliferative disorders using growth hormone secretagogues
ES2430067T3 (es) 2007-03-28 2013-11-18 President And Fellows Of Harvard College Polipéptidos cosidos
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JP2014141507A (ja) 2014-08-07
CN101657436A (zh) 2010-02-24
EP2118080A1 (en) 2009-11-18
EP2644618B1 (en) 2016-08-17
WO2008130464A1 (en) 2008-10-30
US9949949B2 (en) 2018-04-24
US9371297B2 (en) 2016-06-21
US10258602B2 (en) 2019-04-16
US20180228768A1 (en) 2018-08-16
EA200901077A1 (ru) 2010-04-30
US20170042858A1 (en) 2017-02-16
EP2118080B1 (en) 2016-08-31
JP6047514B2 (ja) 2016-12-21
CA2677399C (en) 2016-09-13
JP2010518090A (ja) 2010-05-27
MX2009008574A (es) 2009-12-09
ES2602789T3 (es) 2017-02-22
KR20090107088A (ko) 2009-10-12
CA2677399A1 (en) 2008-10-30
AU2008241532A1 (en) 2008-10-30
US20080194672A1 (en) 2008-08-14

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