AU5486396A - Process for the preparation of spiroindolines - Google Patents

Process for the preparation of spiroindolines

Info

Publication number
AU5486396A
AU5486396A AU54863/96A AU5486396A AU5486396A AU 5486396 A AU5486396 A AU 5486396A AU 54863/96 A AU54863/96 A AU 54863/96A AU 5486396 A AU5486396 A AU 5486396A AU 5486396 A AU5486396 A AU 5486396A
Authority
AU
Australia
Prior art keywords
spiroindolines
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU54863/96A
Inventor
David Askin
Peter E Maligres
Paul J. Reider
Kai Rossen
Jess Sager
Veena Upadhyay
Ralph P. Volante
Kenneth M Wells
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU5486396A publication Critical patent/AU5486396A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU54863/96A 1995-04-19 1996-04-15 Process for the preparation of spiroindolines Abandoned AU5486396A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42512895A 1995-04-19 1995-04-19
US425128 1995-04-19
PCT/US1996/005259 WO1996033189A1 (en) 1995-04-19 1996-04-15 Process for the preparation of spiroindolines

Publications (1)

Publication Number Publication Date
AU5486396A true AU5486396A (en) 1996-11-07

Family

ID=23685282

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54863/96A Abandoned AU5486396A (en) 1995-04-19 1996-04-15 Process for the preparation of spiroindolines

Country Status (3)

Country Link
EP (1) EP0823904A4 (en)
AU (1) AU5486396A (en)
WO (1) WO1996033189A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2333097T3 (en) 2000-05-31 2010-02-17 Raqualia Pharma Inc USE OF SECRETAGOGS OF GROWTH HORMONE TO STIMULATE GASTROINTESTINAL MOTILITY.
BRPI0408295A (en) * 2003-03-14 2006-03-07 Merck Sharp & Dohme use of a compound
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
CU23558A1 (en) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech COMPOUNDS ANALOG TO THE PEPTIDIC SECRETAGOGS OF THE GROWTH HORMONE
BRPI0807046A2 (en) 2007-02-09 2015-05-26 Tranzyme Pharma Inc Compound, pharmaceutical composition, methods of treating a disorder, cardiovascular disease and a patient suffering from reduced or dysfunctional gastrointestinal motility and, kit.
CN102875448B (en) * 2012-11-05 2014-07-02 中国药科大学 Synthetic method for preparing indole spiral cyclopentane derivant
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
WO2017075535A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES468860A1 (en) * 1977-04-21 1979-09-16 Hoechst Ag Spiro(indoline-3,4'-piperidine)s and related compounds
CZ151495A3 (en) * 1992-12-11 1995-12-13 Merck & Co Inc Spiropiperidine derivatives, process of their preparation and a pharmaceutical composition containing thereof
EP0702681A1 (en) * 1993-06-07 1996-03-27 Merck & Co. Inc. Spiro-substituted azacycles as neurokinin antagonists

Also Published As

Publication number Publication date
EP0823904A1 (en) 1998-02-18
EP0823904A4 (en) 1998-09-09
WO1996033189A1 (en) 1996-10-24

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