BR112015023120A2 - método para identificar um indivíduo com uma doença ou disfunção, método para prever a responsividade de um indivíduo com uma doença ou disfunção, método para determinar a probabilidade de que um indivíduo com uma doença ou disfunção exibirá benefício do tratamento, método para selecionar uma terapia, usos de um antagonista de ligação do eixo pd-l1, ensaio para identificar um indivíduo com uma doença, kit de diagnóstico, método para avaliar uma resposta ao tratamento e método para monitorar a resposta de um indivíduo tratado - Google Patents

método para identificar um indivíduo com uma doença ou disfunção, método para prever a responsividade de um indivíduo com uma doença ou disfunção, método para determinar a probabilidade de que um indivíduo com uma doença ou disfunção exibirá benefício do tratamento, método para selecionar uma terapia, usos de um antagonista de ligação do eixo pd-l1, ensaio para identificar um indivíduo com uma doença, kit de diagnóstico, método para avaliar uma resposta ao tratamento e método para monitorar a resposta de um indivíduo tratado

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Publication number
BR112015023120A2
BR112015023120A2 BR112015023120A BR112015023120A BR112015023120A2 BR 112015023120 A2 BR112015023120 A2 BR 112015023120A2 BR 112015023120 A BR112015023120 A BR 112015023120A BR 112015023120 A BR112015023120 A BR 112015023120A BR 112015023120 A2 BR112015023120 A2 BR 112015023120A2
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Brazil
Prior art keywords
individual
disease
dysfunction
response
treatment
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BR112015023120A
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English (en)
Inventor
Shin-Yu Chen Daniel
Koeppen Hartmut
KOWANETZ Marcin
Hegde Priti
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Genentech Inc
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Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112015023120A2 publication Critical patent/BR112015023120A2/pt

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Abstract

resumo “biomarcadores e métodos para tratar condições relacionadas a pd-1 e pd-l1” no presente pedido são fornecidos biomarcadores para o tratamento de condições patológicas, como câncer, e método de uso de antagonistas da via pd-1/pd-l1. em particular, são fornecidos biomarcadores para a seleção de pacientes e prognóstico de câncer, bem como métodos de tratamento terapêutico, artigos de fabricação e métodos para fabricar os mesmos, kits de diagnóstico, métodos de detecção e métodos de publicidade relacionados aos mesmos.
BR112015023120A 2013-03-15 2014-03-12 método para identificar um indivíduo com uma doença ou disfunção, método para prever a responsividade de um indivíduo com uma doença ou disfunção, método para determinar a probabilidade de que um indivíduo com uma doença ou disfunção exibirá benefício do tratamento, método para selecionar uma terapia, usos de um antagonista de ligação do eixo pd-l1, ensaio para identificar um indivíduo com uma doença, kit de diagnóstico, método para avaliar uma resposta ao tratamento e método para monitorar a resposta de um indivíduo tratado BR112015023120A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361802296P 2013-03-15 2013-03-15
US201361812678P 2013-04-16 2013-04-16
US201361829236P 2013-05-30 2013-05-30
US201361883186P 2013-09-26 2013-09-26
PCT/US2014/024746 WO2014151006A2 (en) 2013-03-15 2014-03-12 Biomarkers and methods of treating pd-1 and pd-l1 related conditions

Publications (1)

Publication Number Publication Date
BR112015023120A2 true BR112015023120A2 (pt) 2017-11-21

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BR112015023120A BR112015023120A2 (pt) 2013-03-15 2014-03-12 método para identificar um indivíduo com uma doença ou disfunção, método para prever a responsividade de um indivíduo com uma doença ou disfunção, método para determinar a probabilidade de que um indivíduo com uma doença ou disfunção exibirá benefício do tratamento, método para selecionar uma terapia, usos de um antagonista de ligação do eixo pd-l1, ensaio para identificar um indivíduo com uma doença, kit de diagnóstico, método para avaliar uma resposta ao tratamento e método para monitorar a resposta de um indivíduo tratado

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US (2) US11299544B2 (pt)
EP (3) EP2972373B1 (pt)
JP (2) JP6483082B2 (pt)
KR (5) KR20150131269A (pt)
CN (2) CN110079599A (pt)
AU (4) AU2014235453A1 (pt)
BR (1) BR112015023120A2 (pt)
CA (2) CA3180286A1 (pt)
ES (1) ES2761260T3 (pt)
HK (1) HK1212769A1 (pt)
IL (2) IL241309B (pt)
MX (2) MX2015011774A (pt)
MY (2) MY176706A (pt)
NZ (3) NZ712314A (pt)
PL (1) PL2972373T3 (pt)
RU (1) RU2701378C2 (pt)
SG (2) SG11201507333XA (pt)
WO (1) WO2014151006A2 (pt)

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