BR112015004426A2 - método para reduzir o nível, tratar uma condição, tratar uma condição inflamatória, tratar distúrbio de cd16+, tratar um respondente inadequado de metotrexate, tratar um respondente inadequado de inibidor de tnf, indentificar um sujeito, predizer responsividade e métodos para tratar uma condição inflamatória - Google Patents
método para reduzir o nível, tratar uma condição, tratar uma condição inflamatória, tratar distúrbio de cd16+, tratar um respondente inadequado de metotrexate, tratar um respondente inadequado de inibidor de tnf, indentificar um sujeito, predizer responsividade e métodos para tratar uma condição inflamatóriaInfo
- Publication number
- BR112015004426A2 BR112015004426A2 BR112015004426-3A BR112015004426A BR112015004426A2 BR 112015004426 A2 BR112015004426 A2 BR 112015004426A2 BR 112015004426 A BR112015004426 A BR 112015004426A BR 112015004426 A2 BR112015004426 A2 BR 112015004426A2
- Authority
- BR
- Brazil
- Prior art keywords
- treat
- respondent
- inadequate
- condition
- inflammatory condition
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96486—Metalloendopeptidases (3.4.24)
- G01N2333/96491—Metalloendopeptidases (3.4.24) with definite EC number
- G01N2333/96494—Matrix metalloproteases, e. g. 3.4.24.7
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261695641P | 2012-08-31 | 2012-08-31 | |
US61/695,641 | 2012-08-31 | ||
US201361767989P | 2013-02-22 | 2013-02-22 | |
US61/767,989 | 2013-02-22 | ||
US201361778706P | 2013-03-13 | 2013-03-13 | |
US61/778,706 | 2013-03-13 | ||
PCT/US2013/057442 WO2014036357A1 (en) | 2012-08-31 | 2013-08-30 | Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r) |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015004426A2 true BR112015004426A2 (pt) | 2018-08-28 |
Family
ID=50184395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015004426-3A BR112015004426A2 (pt) | 2012-08-31 | 2013-08-30 | método para reduzir o nível, tratar uma condição, tratar uma condição inflamatória, tratar distúrbio de cd16+, tratar um respondente inadequado de metotrexate, tratar um respondente inadequado de inibidor de tnf, indentificar um sujeito, predizer responsividade e métodos para tratar uma condição inflamatória |
Country Status (14)
Country | Link |
---|---|
US (4) | US20140079699A1 (pt) |
EP (2) | EP2890398A4 (pt) |
JP (3) | JP2015533787A (pt) |
KR (2) | KR20150047593A (pt) |
CN (2) | CN107759690A (pt) |
AU (2) | AU2013308635A1 (pt) |
BR (1) | BR112015004426A2 (pt) |
CA (1) | CA2882804A1 (pt) |
HK (1) | HK1212214A1 (pt) |
IL (1) | IL237351B (pt) |
RU (1) | RU2718751C2 (pt) |
SG (2) | SG11201501413YA (pt) |
TW (2) | TWI713436B (pt) |
WO (1) | WO2014036357A1 (pt) |
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2013
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- 2013-08-30 WO PCT/US2013/057442 patent/WO2014036357A1/en active Application Filing
- 2013-08-30 JP JP2015530076A patent/JP2015533787A/ja not_active Withdrawn
- 2013-08-30 RU RU2015111563A patent/RU2718751C2/ru active
- 2013-08-30 US US14/014,446 patent/US20140079699A1/en not_active Abandoned
- 2013-08-30 SG SG11201501413YA patent/SG11201501413YA/en unknown
- 2013-08-30 CN CN201711051816.7A patent/CN107759690A/zh active Pending
- 2013-08-30 SG SG10201906328RA patent/SG10201906328RA/en unknown
- 2013-08-30 EP EP19151799.4A patent/EP3679949A1/en active Pending
- 2013-08-30 BR BR112015004426-3A patent/BR112015004426A2/pt not_active Application Discontinuation
- 2013-08-30 TW TW102131424A patent/TWI713436B/zh active
- 2013-08-30 KR KR1020157007686A patent/KR20150047593A/ko not_active IP Right Cessation
- 2013-08-30 KR KR1020207035035A patent/KR20200140400A/ko not_active Application Discontinuation
- 2013-08-30 CN CN201380051793.3A patent/CN104684582A/zh active Pending
- 2013-08-30 TW TW107119286A patent/TW201919691A/zh unknown
- 2013-08-30 CA CA2882804A patent/CA2882804A1/en active Pending
- 2013-08-30 AU AU2013308635A patent/AU2013308635A1/en not_active Abandoned
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2015
- 2015-02-22 IL IL237351A patent/IL237351B/en active IP Right Grant
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2016
- 2016-01-06 HK HK16100099.2A patent/HK1212214A1/xx unknown
- 2016-05-13 US US15/154,822 patent/US10221243B2/en active Active
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2018
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2019
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2020
- 2020-09-21 US US17/026,853 patent/US20210107986A1/en active Pending
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AU2018204331B2 (en) | 2020-03-12 |
RU2718751C2 (ru) | 2020-04-14 |
CN104684582A (zh) | 2015-06-03 |
US20140079699A1 (en) | 2014-03-20 |
JP7106386B2 (ja) | 2022-07-26 |
US10221243B2 (en) | 2019-03-05 |
JP2021095415A (ja) | 2021-06-24 |
JP2018197250A (ja) | 2018-12-13 |
TWI713436B (zh) | 2020-12-21 |
SG10201906328RA (en) | 2019-08-27 |
WO2014036357A1 (en) | 2014-03-06 |
TW201919691A (zh) | 2019-06-01 |
EP3679949A1 (en) | 2020-07-15 |
AU2013308635A1 (en) | 2015-03-12 |
US20190248908A1 (en) | 2019-08-15 |
TW201414492A (zh) | 2014-04-16 |
JP2015533787A (ja) | 2015-11-26 |
US10822421B2 (en) | 2020-11-03 |
IL237351A0 (en) | 2015-04-30 |
KR20200140400A (ko) | 2020-12-15 |
CA2882804A1 (en) | 2014-03-06 |
US20210107986A1 (en) | 2021-04-15 |
KR20150047593A (ko) | 2015-05-04 |
SG11201501413YA (en) | 2015-03-30 |
IL237351B (en) | 2020-03-31 |
CN107759690A (zh) | 2018-03-06 |
EP2890398A4 (en) | 2016-03-09 |
RU2015111563A (ru) | 2016-10-20 |
US20160326254A1 (en) | 2016-11-10 |
EP2890398A1 (en) | 2015-07-08 |
HK1212214A1 (en) | 2016-06-10 |
AU2018204331A1 (en) | 2018-07-05 |
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