EP2763540A4 - Compositions and methods for assessing and treating inflammatory diseases and disorders - Google Patents
Compositions and methods for assessing and treating inflammatory diseases and disordersInfo
- Publication number
- EP2763540A4 EP2763540A4 EP12829361.0A EP12829361A EP2763540A4 EP 2763540 A4 EP2763540 A4 EP 2763540A4 EP 12829361 A EP12829361 A EP 12829361A EP 2763540 A4 EP2763540 A4 EP 2763540A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- assessing
- disorders
- compositions
- methods
- inflammatory diseases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161532902P | 2011-09-09 | 2011-09-09 | |
US201261584988P | 2012-01-10 | 2012-01-10 | |
PCT/US2012/033753 WO2013036290A1 (en) | 2011-09-09 | 2012-04-16 | Compositions and methods for assessing and treating inflammatory diseases and disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2763540A1 EP2763540A1 (en) | 2014-08-13 |
EP2763540A4 true EP2763540A4 (en) | 2015-04-22 |
Family
ID=47832488
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12829361.0A Withdrawn EP2763540A4 (en) | 2011-09-09 | 2012-04-16 | Compositions and methods for assessing and treating inflammatory diseases and disorders |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2763540A4 (en) |
WO (1) | WO2013036290A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009062132A2 (en) | 2007-11-09 | 2009-05-14 | California Institute Of Technology | Immunomodulating compounds and related compositions and methods |
ES2694100T3 (en) | 2010-04-07 | 2018-12-18 | California Institute Of Technology | Vehicle to distribute a compound in a mucous membrane and compositions, procedures and related systems |
WO2013009945A1 (en) | 2011-07-12 | 2013-01-17 | The Brigham And Women's Hospital, Inc. | Lipid-containing psa compositions, methods of isolation and methods of use thereof |
BR112015008621A2 (en) | 2012-10-17 | 2018-08-28 | Enterome | METHODS AND DIAGNOSTIC AND / OR PROGNOSTIC KIT IN VITRO NUCLEIC ACID MICRO-ASSEMBLY. |
US9758838B2 (en) | 2013-03-12 | 2017-09-12 | Yale University | Compositions and methods for identifying secretory antibody-bound microbes |
JP2016521284A (en) * | 2013-05-10 | 2016-07-21 | カリフォルニア インスティチュート オブ テクノロジー | Prevention and treatment of colorectal cancer with probiotics |
US10920283B2 (en) | 2013-11-01 | 2021-02-16 | Washington University | Methods to establish and restore normal gut microbiota function of subject in need thereof |
FI127671B (en) | 2014-05-28 | 2018-11-30 | Filip Scheperjans | Method for diagnostics of Parkinson’s disease |
EP3453396A1 (en) | 2014-08-28 | 2019-03-13 | Yale University | Compositions and methods for treating an inflammatory disease or disorder |
US9968616B2 (en) | 2014-10-25 | 2018-05-15 | The Chinese University Of Hong Kong | Discovery of FDA-approved drugs as inhibitors of fatty acid binding protein 4 using molecular docking screening |
US10465224B2 (en) | 2015-02-03 | 2019-11-05 | Mayo Foundation For Medical Education And Research | Methods and materials for assessing and treating arthritis |
WO2016201342A1 (en) | 2015-06-10 | 2016-12-15 | California Institute Of Technology | Sepsis treatment and related compositions methods and systems |
CA2997211A1 (en) | 2015-08-19 | 2017-02-23 | President And Fellows Of Harvard College | Lipidated psa compositions and methods |
WO2018014012A1 (en) | 2016-07-15 | 2018-01-18 | President And Fellows Of Harvard College | Glycolipid compositions and methods of use |
KR20230041709A (en) * | 2020-06-22 | 2023-03-24 | 리제너론 파마슈티칼스 인코포레이티드 | Treatment of obesity with G-protein coupled receptor 75 (GPR75) inhibitors |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004045525A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
WO2005016226A2 (en) * | 2003-08-14 | 2005-02-24 | Hadasit Medical Research Services & Development Ltd. | Pharmaceutical compositions comprising ccr5 antagonists |
WO2011043654A1 (en) * | 2009-10-05 | 2011-04-14 | Aak Patent B.V. | Methods for diagnosing irritable bowel syndrome |
WO2011082218A1 (en) * | 2009-12-31 | 2011-07-07 | Ira Milton Trachtman | Compositions and method for treatment and prophylaxis of inflammatory bowel disease |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
US4160452A (en) | 1977-04-07 | 1979-07-10 | Alza Corporation | Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina |
US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
US5023243A (en) | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
US5190931A (en) | 1983-10-20 | 1993-03-02 | The Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US5168053A (en) | 1989-03-24 | 1992-12-01 | Yale University | Cleavage of targeted RNA by RNAase P |
US5459039A (en) | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5424186A (en) | 1989-06-07 | 1995-06-13 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis |
US5288644A (en) | 1990-04-04 | 1994-02-22 | The Rockefeller University | Instrument and method for the sequencing of genome |
ATE199054T1 (en) | 1990-12-06 | 2001-02-15 | Affymetrix Inc A Delaware Corp | COMPOUNDS AND THEIR USE IN A BINARY SYNTHESIS STRATEGY |
US5384261A (en) | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
AU8126694A (en) | 1993-10-26 | 1995-05-22 | Affymax Technologies N.V. | Arrays of nucleic acid probes on biological chips |
US6159693A (en) | 1998-03-13 | 2000-12-12 | Promega Corporation | Nucleic acid detection |
US6270974B1 (en) | 1998-03-13 | 2001-08-07 | Promega Corporation | Exogenous nucleic acid detection |
EP2280085A3 (en) * | 2004-11-01 | 2011-02-23 | George Mason University | Compositions and methods for diagnosing colon disorders |
US20120004160A1 (en) * | 2009-02-19 | 2012-01-05 | Glaxo Group Ltd. | Methods for identifying and compounds useful for the diagnosis and treatment of diseases involving inflammation |
AU2010286516B2 (en) * | 2009-08-28 | 2016-10-06 | Regeneron Pharmaceuticals, Inc. | Antikine antibodies that bind to multiple CC chemokines |
-
2012
- 2012-04-16 WO PCT/US2012/033753 patent/WO2013036290A1/en active Application Filing
- 2012-04-16 EP EP12829361.0A patent/EP2763540A4/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004045525A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
WO2005016226A2 (en) * | 2003-08-14 | 2005-02-24 | Hadasit Medical Research Services & Development Ltd. | Pharmaceutical compositions comprising ccr5 antagonists |
WO2011043654A1 (en) * | 2009-10-05 | 2011-04-14 | Aak Patent B.V. | Methods for diagnosing irritable bowel syndrome |
WO2011082218A1 (en) * | 2009-12-31 | 2011-07-07 | Ira Milton Trachtman | Compositions and method for treatment and prophylaxis of inflammatory bowel disease |
Non-Patent Citations (5)
Title |
---|
DELPHINE M SAULNIER ET AL: "Gastrointestinal Microbiome Signatures of Pediatric Patients With Irritable Bowel Syndrome", GASTROENTEROLOGY, ELSEVIER, PHILADELPHIA, PA, vol. 141, no. 5, 24 June 2011 (2011-06-24), pages 1782 - 1791, XP028325678, ISSN: 0016-5085, [retrieved on 20110708], DOI: 10.1053/J.GASTRO.2011.06.072 * |
ERAN ELINAV ET AL: "NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis", CELL, CELL PRESS, US, vol. 145, no. 5, 22 April 2011 (2011-04-22), pages 745 - 757, XP028221175, ISSN: 0092-8674, [retrieved on 20110502], DOI: 10.1016/J.CELL.2011.04.022 * |
See also references of WO2013036290A1 * |
YANFEI CHEN ET AL: "Characterization of fecal microbial communities in patients with liver cirrhosis", HEPATOLOGY, vol. 54, no. 2, 26 June 2011 (2011-06-26), pages 562 - 572, XP055159513, ISSN: 0270-9139, DOI: 10.1002/hep.24423 * |
YOUNES J. ERRAHALI ET AL: "CCL26-Targeted siRNA Treatment of Alveolar Type II Cells Decreases Expression of CCR3-Binding Chemokines and Reduces Eosinophil Migration: Implications in Asthma Therapy", JOURNAL OF INTERFERON & CYTOKINE RESEARCH, vol. 29, no. 4, 1 April 2009 (2009-04-01), pages 227 - 239, XP055175655, ISSN: 1079-9907, DOI: 10.1089/jir.2008.0051 * |
Also Published As
Publication number | Publication date |
---|---|
WO2013036290A1 (en) | 2013-03-14 |
EP2763540A1 (en) | 2014-08-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20140409 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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AX | Request for extension of the european patent |
Extension state: BA ME |
|
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20150319 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A01N 63/00 20060101AFI20150313BHEP |
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17Q | First examination report despatched |
Effective date: 20160420 |
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GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
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INTG | Intention to grant announced |
Effective date: 20170315 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20170726 |