BR112012008833A2 - imunoglobulinas de dominio variavel duplo e usos das mesmas - Google Patents
imunoglobulinas de dominio variavel duplo e usos das mesmasInfo
- Publication number
- BR112012008833A2 BR112012008833A2 BR112012008833A BR112012008833A BR112012008833A2 BR 112012008833 A2 BR112012008833 A2 BR 112012008833A2 BR 112012008833 A BR112012008833 A BR 112012008833A BR 112012008833 A BR112012008833 A BR 112012008833A BR 112012008833 A2 BR112012008833 A2 BR 112012008833A2
- Authority
- BR
- Brazil
- Prior art keywords
- variable domain
- double variable
- domain immunoglobulins
- immunoglobulins
- double
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 2
- 102000018358 immunoglobulin Human genes 0.000 title abstract 2
- 229940072221 immunoglobulins Drugs 0.000 title abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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Applications Claiming Priority (2)
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| US25180409P | 2009-10-15 | 2009-10-15 | |
| PCT/US2010/052843 WO2011047262A2 (en) | 2009-10-15 | 2010-10-15 | Dual variable domain immunoglobulins and uses thereof |
Publications (1)
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| BR112012008833A2 true BR112012008833A2 (pt) | 2015-09-08 |
Family
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| BR112012008833A BR112012008833A2 (pt) | 2009-10-15 | 2010-10-15 | imunoglobulinas de dominio variavel duplo e usos das mesmas |
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| IL219119A0 (en) | 2012-06-28 |
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| AU2010306677A1 (en) | 2012-05-31 |
| CL2012000957A1 (es) | 2013-09-06 |
| KR20140015139A (ko) | 2014-02-06 |
| CN102666875A (zh) | 2012-09-12 |
| WO2011047262A4 (en) | 2011-11-10 |
| RU2012119756A (ru) | 2013-11-20 |
| US8716450B2 (en) | 2014-05-06 |
| US20110091463A1 (en) | 2011-04-21 |
| AU2010306677B2 (en) | 2013-05-23 |
| EP2488658A4 (en) | 2013-06-19 |
| DOP2012000104A (es) | 2013-01-31 |
| CR20120248A (es) | 2012-08-14 |
| MX2012004415A (es) | 2012-05-08 |
| ECSP12011885A (es) | 2012-07-31 |
| AR078651A1 (es) | 2011-11-23 |
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