BR112012032778A2 - "proteínas multiespecíficas e multivalentes" - Google Patents

"proteínas multiespecíficas e multivalentes"

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Publication number
BR112012032778A2
BR112012032778A2 BR112012032778A BR112012032778A BR112012032778A2 BR 112012032778 A2 BR112012032778 A2 BR 112012032778A2 BR 112012032778 A BR112012032778 A BR 112012032778A BR 112012032778 A BR112012032778 A BR 112012032778A BR 112012032778 A2 BR112012032778 A2 BR 112012032778A2
Authority
BR
Brazil
Prior art keywords
multispecific
multivalent
multivalent proteins
proteins
disease
Prior art date
Application number
BR112012032778A
Other languages
English (en)
Inventor
J Jakway James
Liu Junjian
Benatuil Lorenzo
V Talanian Robert
Ghayur Tariq
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of BR112012032778A2 publication Critical patent/BR112012032778A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/64—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising a combination of variable region and constant region components

Abstract

"proteínas multiespecíficas e multivalentes"a presente invenção refere-se a proteinas de ligação multiespecíficas e multivalente projetadas aos métodos de fabricação,e especificamente aos seus usos para a prevenção diagnóstica e/ou tratamento da doença.
BR112012032778A 2010-06-24 2011-06-23 "proteínas multiespecíficas e multivalentes" BR112012032778A2 (pt)

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PCT/US2011/041633 WO2011163478A2 (en) 2010-06-24 2011-06-23 Dual variable domain immunoglobulins and uses thereof

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WO2011163478A3 (en) 2012-05-03
EP2585607A2 (en) 2013-05-01
CO6650372A2 (es) 2013-04-15
RU2013103060A (ru) 2014-07-27
ZA201300623B (en) 2014-05-28
CN103200963A (zh) 2013-07-10
CA2803392A1 (en) 2011-12-29
JP2013539353A (ja) 2013-10-24
EP2585607A4 (en) 2014-01-22
US20110318349A1 (en) 2011-12-29
WO2011163478A4 (en) 2012-07-05
KR20130043168A (ko) 2013-04-29
ECSP13012402A (es) 2013-03-28
SG188944A1 (en) 2013-05-31
PE20130614A1 (es) 2013-07-01
AU2011270848A1 (en) 2013-02-07
CL2012003610A1 (es) 2013-05-17
TW201204831A (en) 2012-02-01

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