ATE549358T1 - Neuer anti-plgf-antikörper - Google Patents

Neuer anti-plgf-antikörper

Info

Publication number
ATE549358T1
ATE549358T1 AT06721544T AT06721544T ATE549358T1 AT E549358 T1 ATE549358 T1 AT E549358T1 AT 06721544 T AT06721544 T AT 06721544T AT 06721544 T AT06721544 T AT 06721544T AT E549358 T1 ATE549358 T1 AT E549358T1
Authority
AT
Austria
Prior art keywords
new anti
plgf antibody
fragments
plgf
antibody
Prior art date
Application number
AT06721544T
Other languages
English (en)
Inventor
Jean-Marie Stassen
Peter Carmeliet
Desire Collen
Original Assignee
Thrombogenics Nv
Life Sciences Res Partners
Vlaams Interuniv Inst Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombogenics Nv, Life Sciences Res Partners, Vlaams Interuniv Inst Biotech filed Critical Thrombogenics Nv
Application granted granted Critical
Publication of ATE549358T1 publication Critical patent/ATE549358T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
AT06721544T 2005-03-24 2006-03-24 Neuer anti-plgf-antikörper ATE549358T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66476805P 2005-03-24 2005-03-24
PCT/BE2006/000023 WO2006099698A2 (en) 2005-03-24 2006-03-24 Novel anti-plgf antibody

Publications (1)

Publication Number Publication Date
ATE549358T1 true ATE549358T1 (de) 2012-03-15

Family

ID=36928446

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06721544T ATE549358T1 (de) 2005-03-24 2006-03-24 Neuer anti-plgf-antikörper

Country Status (27)

Country Link
US (3) US7875704B2 (de)
EP (2) EP1869085B1 (de)
JP (2) JP5164829B2 (de)
KR (1) KR101314014B1 (de)
CN (1) CN101184776B (de)
AT (1) ATE549358T1 (de)
AU (2) AU2006227571B8 (de)
BR (1) BRPI0609151B8 (de)
CA (1) CA2601267C (de)
CY (1) CY1113224T1 (de)
DK (1) DK1869085T3 (de)
EA (1) EA013970B1 (de)
ES (2) ES2384110T3 (de)
HK (1) HK1116803A1 (de)
HR (1) HRP20120477T1 (de)
IL (1) IL185754A (de)
ME (1) ME01446B (de)
MX (1) MX2007011735A (de)
NO (1) NO341877B1 (de)
NZ (1) NZ561763A (de)
PL (1) PL1869085T3 (de)
PT (1) PT1869085E (de)
RS (1) RS52372B (de)
SI (1) SI1869085T1 (de)
UA (1) UA94707C2 (de)
WO (1) WO2006099698A2 (de)
ZA (1) ZA200707258B (de)

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MX2007011735A (es) 2005-03-24 2008-03-14 Thrombogenics Nv Anticuerpo anti-plgf novedoso.
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TW201710286A (zh) 2015-06-15 2017-03-16 艾伯維有限公司 抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
CN104930353B (zh) * 2015-07-10 2017-08-15 浙江大学 一种城市供水管网的调压减漏评估系统
EP3426685A1 (de) 2016-03-10 2019-01-16 Oxurion NV Hintere okularfibrosehemmung durch antagonisierung des plazentalen wachstumsfaktors
EP3471767A4 (de) 2016-06-15 2020-01-15 Icahn School of Medicine at Mount Sinai Influenzavirus-hämagglutinin-proteine und verwendungen davon
EP3606555A4 (de) * 2017-04-07 2021-08-04 Icahn School of Medicine at Mount Sinai Neuraminidase-antikörper gegen influenza-b-virus und verwendungen davon
CN109134650A (zh) * 2018-09-10 2019-01-04 宁波奥丞生物科技有限公司 抗人plgf单克隆抗体的制备方法
WO2020239945A1 (en) 2019-05-28 2020-12-03 Vib Vzw Cancer treatment by targeting plexins in the immune compartment
EP3976067A1 (de) 2019-05-28 2022-04-06 Vib Vzw Cd8+-t-zellen ohne plexine und ihre anwendung zur krebsbehandlung
WO2020260595A1 (en) 2019-06-26 2020-12-30 Oncurious Nv Combination treatment of medulloblastoma using a placental growth factor inhibitor and a chemotherapeutic agent
EP3936868A1 (de) 2020-07-10 2022-01-12 Charité - Universitätsmedizin Berlin Verhältnis zwischen plgf und sflt1, das prädiktiv für die neurale invasion bei patienten mit pankreaskrebs ist
WO2022063957A1 (en) 2020-09-24 2022-03-31 Vib Vzw Biomarker for anti-tumor therapy
CN112358546B (zh) * 2020-11-10 2022-04-01 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其应用
WO2022099465A1 (zh) * 2020-11-10 2022-05-19 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其制备方法和应用
CA3203072A1 (en) 2020-12-22 2022-06-30 Andrea CASAZZA Compounds comprising a tetrapeptidic moiety
CN113999310A (zh) * 2020-12-30 2022-02-01 江苏普若维生物技术有限责任公司 一种plgf单克隆抗体、试剂盒、其制备方法和应用
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Also Published As

Publication number Publication date
CN101184776B (zh) 2013-04-24
NO341877B1 (no) 2018-02-12
EP1869085B1 (de) 2012-03-14
EP2447281A1 (de) 2012-05-02
KR101314014B1 (ko) 2013-10-02
US20110123525A1 (en) 2011-05-26
RS52372B (en) 2012-12-31
US20080193455A1 (en) 2008-08-14
JP2012136522A (ja) 2012-07-19
CY1113224T1 (el) 2016-04-13
IL185754A (en) 2013-02-28
KR20080016794A (ko) 2008-02-22
WO2006099698A2 (en) 2006-09-28
SI1869085T1 (sl) 2012-07-31
AU2006227571B8 (en) 2011-01-27
HK1116803A1 (en) 2009-01-02
US8758748B2 (en) 2014-06-24
BRPI0609151A2 (pt) 2010-02-17
UA94707C2 (en) 2011-06-10
AU2006227571A1 (en) 2006-09-28
AU2011201340A1 (en) 2011-04-14
PT1869085E (pt) 2012-06-01
JP5164829B2 (ja) 2013-03-21
EA200702064A1 (ru) 2008-02-28
US20140178397A1 (en) 2014-06-26
HRP20120477T1 (hr) 2012-07-31
IL185754A0 (en) 2008-01-06
CN101184776A (zh) 2008-05-21
WO2006099698A3 (en) 2006-11-30
US7875704B2 (en) 2011-01-25
AU2006227571B2 (en) 2010-12-23
US9085617B2 (en) 2015-07-21
ME01446B (me) 2013-12-20
CA2601267A1 (en) 2006-09-28
BRPI0609151B8 (pt) 2021-05-25
JP2008532557A (ja) 2008-08-21
ES2384110T3 (es) 2012-06-29
MX2007011735A (es) 2008-03-14
PL1869085T3 (pl) 2012-09-28
ES2565481T3 (es) 2016-04-05
EA013970B1 (ru) 2010-08-30
NZ561763A (en) 2009-02-28
NO20074563L (no) 2007-12-18
BRPI0609151B1 (pt) 2020-01-21
CA2601267C (en) 2014-02-18
AU2011201340B2 (en) 2012-02-23
EP2447281B1 (de) 2015-12-16
ZA200707258B (en) 2008-06-25
EP1869085A2 (de) 2007-12-26
DK1869085T3 (da) 2012-06-18

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