IT1242149B - Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi - Google Patents

Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi

Info

Publication number
IT1242149B
IT1242149B IT48315A IT4831590A IT1242149B IT 1242149 B IT1242149 B IT 1242149B IT 48315 A IT48315 A IT 48315A IT 4831590 A IT4831590 A IT 4831590A IT 1242149 B IT1242149 B IT 1242149B
Authority
IT
Italy
Prior art keywords
angiogenesis
coding
human protein
pct
regulatory properties
Prior art date
Application number
IT48315A
Other languages
English (en)
Other versions
IT9048315A0 (it
IT9048315A1 (it
Inventor
Maria Persico
Domenico Maglione
Original Assignee
Consiglio Nazionale Ricerche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11265849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1242149(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Consiglio Nazionale Ricerche filed Critical Consiglio Nazionale Ricerche
Priority to IT48315A priority Critical patent/IT1242149B/it
Publication of IT9048315A0 publication Critical patent/IT9048315A0/it
Priority to PCT/IT1991/000079 priority patent/WO1992006194A1/en
Priority to US08/039,297 priority patent/US5919899A/en
Priority to ES91916657T priority patent/ES2127730T3/es
Priority to JP3515286A priority patent/JP2987203B2/ja
Priority to AU86353/91A priority patent/AU8635391A/en
Priority to AT91916657T priority patent/ATE173505T1/de
Priority to DE69130506T priority patent/DE69130506T2/de
Priority to EP91916657A priority patent/EP0550519B1/en
Priority to CA002092533A priority patent/CA2092533C/en
Publication of IT9048315A1 publication Critical patent/IT9048315A1/it
Publication of IT1242149B publication Critical patent/IT1242149B/it
Application granted granted Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
IT48315A 1990-09-27 1990-09-27 Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi IT1242149B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT48315A IT1242149B (it) 1990-09-27 1990-09-27 Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
CA002092533A CA2092533C (en) 1990-09-27 1991-09-26 Nucleotide sequences coding for a human protein with angiogenesis regulative properties
PCT/IT1991/000079 WO1992006194A1 (en) 1990-09-27 1991-09-26 Nucleotide sequences coding for a human protein with angiogenesis regulative properties
US08/039,297 US5919899A (en) 1990-09-27 1991-09-26 Human protein with angiogenesis regulative properties
ES91916657T ES2127730T3 (es) 1990-09-27 1991-09-26 Secuencias de nucleotidos que codifican una proteina humana que tiene propiedades reguladoras de la angiogenesis.
JP3515286A JP2987203B2 (ja) 1990-09-27 1991-09-26 アンギオジェネシス制御特性を有するヒト蛋白をコードするヌクレオチド配列
AU86353/91A AU8635391A (en) 1990-09-27 1991-09-26 Nucleotide sequences coding for a human protein with angiogenesis regulative properties
AT91916657T ATE173505T1 (de) 1990-09-27 1991-09-26 Nukleotidsequenzen kodierend für ein humanes protein mit angiogenetisch-regulatorischen eigenschaften
DE69130506T DE69130506T2 (de) 1990-09-27 1991-09-26 Nukleotidsequenzen kodierend für ein humanes protein mit angiogenetisch-regulatorischen eigenschaften
EP91916657A EP0550519B1 (en) 1990-09-27 1991-09-26 Nucleotide sequences coding for a human protein with angiogenesis regulative properties

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48315A IT1242149B (it) 1990-09-27 1990-09-27 Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi

Publications (3)

Publication Number Publication Date
IT9048315A0 IT9048315A0 (it) 1990-09-27
IT9048315A1 IT9048315A1 (it) 1992-03-27
IT1242149B true IT1242149B (it) 1994-02-16

Family

ID=11265849

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48315A IT1242149B (it) 1990-09-27 1990-09-27 Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi

Country Status (10)

Country Link
US (1) US5919899A (it)
EP (1) EP0550519B1 (it)
JP (1) JP2987203B2 (it)
AT (1) ATE173505T1 (it)
AU (1) AU8635391A (it)
CA (1) CA2092533C (it)
DE (1) DE69130506T2 (it)
ES (1) ES2127730T3 (it)
IT (1) IT1242149B (it)
WO (1) WO1992006194A1 (it)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69229454T2 (de) * 1991-03-28 2000-01-05 Merck & Co Inc Untereinheit-C des vaskulären endothelialen Zellwachstumsfaktors
US7429646B1 (en) 1995-06-05 2008-09-30 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor-like 2
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
WO1998027932A2 (en) * 1996-12-20 1998-07-02 Human Genome Sciences, Inc. Cerebellum and embryo specific protein
AU7250298A (en) * 1997-04-25 1998-11-24 Collateral Therapeutics, Inc. Truncated vegf-related proteins
EP2357192A1 (en) 1999-02-26 2011-08-17 Human Genome Sciences, Inc. Human endokine alpha and methods of use
US20020164812A1 (en) * 1999-04-06 2002-11-07 Uab Research Foundation Method for screening crystallization conditions in solution crystal growth
US7105168B1 (en) * 2002-06-04 2006-09-12 D. Collen Research Foundation Vzw Method of improving ischemic muscle function by administering placental growth factor
US7727971B2 (en) * 2000-02-04 2010-06-01 Life Sciences Research Partners Vzw Use of placental growth factor for treating ischemic muscle disease
EP1274720A4 (en) 2000-04-12 2004-08-18 Human Genome Sciences Inc ALBUMIN FUSED PROTEINS
EP1297016B1 (en) * 2000-05-12 2006-03-22 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Use of inhibitors of placental growth factor for the treatment of pathological angiogenesis, pathological arteriogenesis, inflammation, tumour formation and/or vascular leakage
AU2002340080A1 (en) * 2001-10-03 2003-04-14 Regeneron Pharmaceuticals, Inc. Anti-angiogenic peptides
CA2841097A1 (en) 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin and g-csf fusion proteins
EE05407B1 (et) * 2002-02-05 2011-04-15 Geymonat S.P.A. Protsess rekombinantse platsenta kasvuteguri tootmiseks
ITRM20020119A1 (it) 2002-03-05 2003-09-05 Geymonat Spa Composizioni contenenti plgf ad uso farmaceutico e cosmetico.
ITRM20020277A1 (it) * 2002-05-17 2003-11-17 Geymonat Spa Muteine del fattore di crescita placentare tipo 1, metodo di preparazione e loro applicazioni.
ATE394679T1 (de) 2002-11-16 2008-05-15 Dade Behring Marburg Gmbh Scd40l, papp-a und plazentaler-wachstumsfaktor (pigf) als biochemische markerkombinationen bei kardiovaskulären erkrankungen
WO2005087812A1 (en) * 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Multivalent antibody materials and methods for vegf/pdgf family of growth factors
US20060024302A1 (en) * 2004-03-05 2006-02-02 Ludwig Institute For Cancer Research Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same
EP2447281B1 (en) * 2005-03-24 2015-12-16 ThromboGenics N.V. Novel anti-PLGF antibody
DE102005022047A1 (de) 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
EP1904095B1 (en) * 2005-06-30 2013-05-29 VIB, vzw Treatment of liver cirrhosis and its complications
AU2006267097A1 (en) * 2005-07-13 2007-01-18 Beth Israel Deaconess Medical Center Methods of diagnosing and treating an inflammatory response
DE602006020881D1 (de) * 2005-08-15 2011-05-05 Vegenics Pty Ltd Enen eigenschaften
DK2548578T3 (da) 2006-05-17 2014-10-06 Ludwig Inst Cancer Res Målretning af VEGF-B-regulering af fedtsyretransportører til modulering af humane sygdomme
WO2009082485A1 (en) 2007-12-26 2009-07-02 Vaccinex, Inc. Anti-c35 antibody combination therapies and methods
EP2238448B1 (en) 2008-01-07 2016-04-06 Ortho-Clinical Diagnostics, Inc. Calibrator/control for simultaneous assay of proteins capable of complexing with one another
US20100004306A1 (en) * 2008-06-18 2010-01-07 Abbott Laboratories PIGF-1 Assay and kits and components thereof
US8741287B2 (en) 2008-06-18 2014-06-03 Abbott Laboratories PlGF-1 assay and kits and components thereof
KR101798664B1 (ko) 2008-10-02 2017-11-16 브이아이비 브이지더블유 필라델피아 염색체 양성 백혈병의 치료를 위한 피엘지에프의 억제
EP2295449A1 (en) 2009-09-09 2011-03-16 Dompe PHA.R.MA S.p.A. PLGF-1 in homodimeric form
CN103087153B (zh) * 2011-10-28 2015-05-06 上海市第一人民医院 一类新的抑制新生血管的小肽及其应用
ES2628321T3 (es) 2011-12-01 2017-08-02 Thrombogenics N.V. Mejora del resultado de una trabeculectomía
WO2014055849A1 (en) 2012-10-05 2014-04-10 Alere San Diego, Inc. Methods for diagnosing and prognosing placental dysfunction and pre-eclampsia

Also Published As

Publication number Publication date
WO1992006194A1 (en) 1992-04-16
EP0550519B1 (en) 1998-11-18
CA2092533C (en) 2002-05-28
EP0550519A1 (en) 1993-07-14
AU8635391A (en) 1992-04-28
DE69130506T2 (de) 1999-06-24
ATE173505T1 (de) 1998-12-15
IT9048315A0 (it) 1990-09-27
US5919899A (en) 1999-07-06
JPH06503225A (ja) 1994-04-14
JP2987203B2 (ja) 1999-12-06
CA2092533A1 (en) 1992-03-28
ES2127730T3 (es) 1999-05-01
IT9048315A1 (it) 1992-03-27
DE69130506D1 (de) 1998-12-24

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960920