ATE498010T1 - Natürliche igm-antikörper und inhibitoren davon - Google Patents
Natürliche igm-antikörper und inhibitoren davonInfo
- Publication number
- ATE498010T1 ATE498010T1 AT05723931T AT05723931T ATE498010T1 AT E498010 T1 ATE498010 T1 AT E498010T1 AT 05723931 T AT05723931 T AT 05723931T AT 05723931 T AT05723931 T AT 05723931T AT E498010 T1 ATE498010 T1 AT E498010T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- natural igm
- igm antibodies
- natural
- disorders
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54912304P | 2004-03-01 | 2004-03-01 | |
| US58864804P | 2004-07-16 | 2004-07-16 | |
| PCT/US2005/006276 WO2005085288A2 (en) | 2004-03-01 | 2005-03-01 | Natural igm antibodies and inhibitors thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE498010T1 true ATE498010T1 (de) | 2011-02-15 |
Family
ID=34922704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05723931T ATE498010T1 (de) | 2004-03-01 | 2005-03-01 | Natürliche igm-antikörper und inhibitoren davon |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US7442783B2 (de) |
| EP (2) | EP1725659B1 (de) |
| JP (3) | JP5557982B2 (de) |
| AT (1) | ATE498010T1 (de) |
| AU (1) | AU2005219839B9 (de) |
| CA (1) | CA2560066A1 (de) |
| DE (1) | DE602005026260D1 (de) |
| IL (1) | IL177825A (de) |
| WO (1) | WO2005085288A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005085288A2 (en) | 2004-03-01 | 2005-09-15 | The Cbr Institute For Biomedical Research | Natural igm antibodies and inhibitors thereof |
| US20100136684A1 (en) * | 2004-03-01 | 2010-06-03 | Carroll Michael C | Natural IgM Antibodies |
| AU2010328359B2 (en) * | 2009-12-07 | 2015-02-05 | Decimmune Therapeutics, Inc. | Anti-inflammatory antibodies and uses therefor |
| CN103221062A (zh) * | 2010-06-03 | 2013-07-24 | 阿布拉西斯生物科学有限责任公司 | 外周血sparc 结合抗体及其用途 |
| WO2014055392A2 (en) * | 2012-10-01 | 2014-04-10 | Decimmune Therapeutics, Inc. | Method of protecting cardiac function |
| CA2905940A1 (en) | 2013-03-12 | 2014-10-09 | Decimmune Therapeutics, Inc. | Humanized, anti-n2 antibodies |
| JP6551825B2 (ja) * | 2014-02-10 | 2019-07-31 | 公立大学法人首都大学東京 | クロマチン構造制御剤 |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (de) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimäre Rezeptoren durch Verbindung und Expression von DNS |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5266480A (en) | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
| DE768377T1 (de) | 1988-09-02 | 1998-01-02 | Dyax Corp | Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| EP0411060A4 (en) | 1988-09-06 | 1991-04-03 | Asarco Incorporated | Method and burner for melting copper |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5198346A (en) | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
| US5096815A (en) | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
| WO1991000906A1 (en) | 1989-07-12 | 1991-01-24 | Genetics Institute, Inc. | Chimeric and transgenic animals capable of producing human antibodies |
| EP0502060A4 (en) | 1989-11-13 | 1993-05-05 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
| AU7163091A (en) * | 1989-12-12 | 1991-07-18 | Biomedical Research Institute | Novel malarial sporozoite peptide antigens |
| ATE139258T1 (de) | 1990-01-12 | 1996-06-15 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| AU8507191A (en) | 1990-08-29 | 1992-03-30 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| AU664976B2 (en) | 1990-08-29 | 1995-12-14 | Gene Pharming Europe Bv | Homologous recombination in mammalian cells |
| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
| EP0562025B1 (de) | 1990-12-06 | 2001-02-07 | Affymetrix, Inc. (a Delaware Corporation) | Verbindungen und ihre Verwendung in einer binären Synthesestrategie |
| ES2287206T3 (es) | 1991-03-01 | 2007-12-16 | Dyax Corporation | Proceso para el desarrollo de mini-proteinas de union. |
| WO1992018619A1 (en) | 1991-04-10 | 1992-10-29 | The Scripps Research Institute | Heterodimeric receptor libraries using phagemids |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| WO1993009668A1 (en) | 1991-11-22 | 1993-05-27 | Affymax Technology N.V. | Combinatorial strategies for polymer synthesis |
| US5233409A (en) | 1992-02-25 | 1993-08-03 | Schwab Karl W | Color analysis of organic constituents in sedimentary rocks for thermal maturity |
| US5359115A (en) | 1992-03-26 | 1994-10-25 | Affymax Technologies, N.V. | Methods for the synthesis of phosphonate esters |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| US5288514A (en) | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| PT665897E (pt) | 1992-10-01 | 2003-11-28 | Trustees Of Columbia U In The | Bibliotecas quimicas combinatorias complexas codificadas com etiquetas |
| US6174530B1 (en) | 1993-05-05 | 2001-01-16 | Gryphon Sciences | Homogeneous polyoxime compositions and their preparation by parallel assembly |
| WO1994029351A2 (en) | 1993-06-16 | 1994-12-22 | Celltech Limited | Antibodies |
| US5362899A (en) | 1993-09-09 | 1994-11-08 | Affymax Technologies, N.V. | Chiral synthesis of alpha-aminophosponic acids |
| US6184344B1 (en) | 1995-05-04 | 2001-02-06 | The Scripps Research Institute | Synthesis of proteins by native chemical ligation |
| US6376653B1 (en) | 1998-09-28 | 2002-04-23 | Smithkline Beecham Plc | Tie2 antagonist antibodies |
| WO2001064835A2 (en) * | 2000-02-28 | 2001-09-07 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| EP1135535A2 (de) * | 1998-12-03 | 2001-09-26 | Phagetech Inc. | Entwicklung von antimikrobiellen mittel auf der basis des bakteriophagen-genoms |
| WO2000042210A2 (en) | 1999-01-15 | 2000-07-20 | International Paper Company | Microsatellite dna markers and uses thereof |
| US6753314B1 (en) * | 1999-04-01 | 2004-06-22 | Curagen Corporation | Protein-protein complexes and methods of using same |
| AU5625500A (en) * | 1999-06-18 | 2001-01-09 | Emory University | Huntington disease cellular model: stably transfected pc12 cells expressing mutant huntingtin |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| AU2001263006A1 (en) * | 2000-05-18 | 2001-11-26 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| AU2001275378A1 (en) * | 2000-06-08 | 2001-12-17 | The Center For Blood Research, Inc. | Methods and compositions for inhibiting immunoglobulin-mediated reperfusion inj ury |
| CA2424379C (en) * | 2000-10-10 | 2013-10-01 | Tanox, Inc. | Inhibition of complement c5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection |
| US7319139B2 (en) * | 2001-01-29 | 2008-01-15 | Biogen Idec, Inc. | TAG-72 specific CH2 domain deleted antibodies |
| US20040131607A1 (en) | 2001-06-08 | 2004-07-08 | Carroll Michael C. | Methods and compositions for inhibiting immunoglobulin-mediated reperfusion injury |
| AU2002364105A1 (en) * | 2001-12-21 | 2003-07-15 | Diadexus, Inc. | Compositions and methods relating to endometrial specific genes and proteins |
| AU2002357382A1 (en) * | 2001-12-21 | 2003-07-30 | Diadexus, Inc. | Compositions and methods relating to endometrial specific genes and proteins |
| US7709610B2 (en) * | 2003-05-08 | 2010-05-04 | Facet Biotech Corporation | Therapeutic use of anti-CS1 antibodies |
| WO2005085288A2 (en) | 2004-03-01 | 2005-09-15 | The Cbr Institute For Biomedical Research | Natural igm antibodies and inhibitors thereof |
| US20100136684A1 (en) | 2004-03-01 | 2010-06-03 | Carroll Michael C | Natural IgM Antibodies |
| US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| IT1395574B1 (it) | 2009-09-14 | 2012-10-16 | Guala Dispensing Spa | Dispositivo di erogazione |
-
2005
- 2005-03-01 WO PCT/US2005/006276 patent/WO2005085288A2/en not_active Ceased
- 2005-03-01 EP EP05723931A patent/EP1725659B1/de not_active Expired - Lifetime
- 2005-03-01 DE DE602005026260T patent/DE602005026260D1/de not_active Expired - Lifetime
- 2005-03-01 AT AT05723931T patent/ATE498010T1/de not_active IP Right Cessation
- 2005-03-01 JP JP2007501869A patent/JP5557982B2/ja not_active Expired - Fee Related
- 2005-03-01 CA CA002560066A patent/CA2560066A1/en not_active Abandoned
- 2005-03-01 EP EP10185693.8A patent/EP2290077B1/de not_active Expired - Lifetime
- 2005-03-01 US US11/069,834 patent/US7442783B2/en not_active Expired - Lifetime
- 2005-03-01 AU AU2005219839A patent/AU2005219839B9/en not_active Ceased
-
2006
- 2006-08-31 IL IL177825A patent/IL177825A/en not_active IP Right Cessation
-
2008
- 2008-10-28 US US12/259,767 patent/US20090176966A1/en not_active Abandoned
-
2011
- 2011-02-01 JP JP2011019668A patent/JP5618852B2/ja not_active Expired - Fee Related
-
2013
- 2013-04-09 US US13/859,054 patent/US9657060B2/en not_active Expired - Fee Related
-
2014
- 2014-04-24 JP JP2014089965A patent/JP2014155497A/ja active Pending
-
2015
- 2015-07-23 US US14/806,924 patent/US9914751B2/en not_active Expired - Lifetime
-
2017
- 2017-05-08 US US15/588,933 patent/US20170342109A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005026260D1 (de) | 2011-03-24 |
| AU2005219839A1 (en) | 2005-09-15 |
| IL177825A (en) | 2013-02-28 |
| AU2005219839B2 (en) | 2011-11-24 |
| EP2290077A3 (de) | 2011-05-18 |
| US7442783B2 (en) | 2008-10-28 |
| US9914751B2 (en) | 2018-03-13 |
| US20170342109A1 (en) | 2017-11-30 |
| WO2005085288A2 (en) | 2005-09-15 |
| JP2008504807A (ja) | 2008-02-21 |
| US20050276811A1 (en) | 2005-12-15 |
| CA2560066A1 (en) | 2005-09-15 |
| EP1725659A2 (de) | 2006-11-29 |
| US9657060B2 (en) | 2017-05-23 |
| WO2005085288A3 (en) | 2006-08-03 |
| JP2014155497A (ja) | 2014-08-28 |
| JP2011139704A (ja) | 2011-07-21 |
| IL177825A0 (en) | 2006-12-31 |
| US20090176966A1 (en) | 2009-07-09 |
| EP2290077B1 (de) | 2016-01-27 |
| US20140127214A1 (en) | 2014-05-08 |
| EP2290077A2 (de) | 2011-03-02 |
| JP5557982B2 (ja) | 2014-07-23 |
| HK1154904A1 (en) | 2012-05-04 |
| EP1725659B1 (de) | 2011-02-09 |
| AU2005219839B9 (en) | 2011-12-22 |
| JP5618852B2 (ja) | 2014-11-05 |
| US20160280740A1 (en) | 2016-09-29 |
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| ATE498010T1 (de) | Natürliche igm-antikörper und inhibitoren davon |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |