DE602005026260D1 - Natürliche igm-antikörper und inhibitoren davon - Google Patents
Natürliche igm-antikörper und inhibitoren davonInfo
- Publication number
- DE602005026260D1 DE602005026260D1 DE602005026260T DE602005026260T DE602005026260D1 DE 602005026260 D1 DE602005026260 D1 DE 602005026260D1 DE 602005026260 T DE602005026260 T DE 602005026260T DE 602005026260 T DE602005026260 T DE 602005026260T DE 602005026260 D1 DE602005026260 D1 DE 602005026260D1
- Authority
- DE
- Germany
- Prior art keywords
- inhibitors
- natural igm
- igm antibodies
- natural
- disorders
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 208000027866 inflammatory disease Diseases 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54912304P | 2004-03-01 | 2004-03-01 | |
US58864804P | 2004-07-16 | 2004-07-16 | |
PCT/US2005/006276 WO2005085288A2 (en) | 2004-03-01 | 2005-03-01 | Natural igm antibodies and inhibitors thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005026260D1 true DE602005026260D1 (de) | 2011-03-24 |
Family
ID=34922704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005026260T Active DE602005026260D1 (de) | 2004-03-01 | 2005-03-01 | Natürliche igm-antikörper und inhibitoren davon |
Country Status (10)
Country | Link |
---|---|
US (5) | US7442783B2 (de) |
EP (2) | EP1725659B1 (de) |
JP (3) | JP5557982B2 (de) |
AT (1) | ATE498010T1 (de) |
AU (1) | AU2005219839B9 (de) |
CA (1) | CA2560066A1 (de) |
DE (1) | DE602005026260D1 (de) |
HK (1) | HK1154904A1 (de) |
IL (1) | IL177825A (de) |
WO (1) | WO2005085288A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100136684A1 (en) * | 2004-03-01 | 2010-06-03 | Carroll Michael C | Natural IgM Antibodies |
ATE498010T1 (de) | 2004-03-01 | 2011-02-15 | Immune Disease Inst Inc | Natürliche igm-antikörper und inhibitoren davon |
CA2783563A1 (en) * | 2009-12-07 | 2011-06-16 | Decimmune Therapeutics, Inc. | Anti-inflammatory antibodies and uses therefor |
AU2011261270A1 (en) * | 2010-06-03 | 2012-12-13 | Abraxis Bioscience, Llc | Peripheral blood SPARC antibodies and uses thereof |
WO2014055392A2 (en) * | 2012-10-01 | 2014-04-10 | Decimmune Therapeutics, Inc. | Method of protecting cardiac function |
WO2014165115A1 (en) | 2013-03-12 | 2014-10-09 | Decimmune Therapeutics, Inc. | Humanized anti-n2 antibodies |
JP6551825B2 (ja) * | 2014-02-10 | 2019-07-31 | 公立大学法人首都大学東京 | クロマチン構造制御剤 |
Family Cites Families (60)
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
EP0173494A3 (de) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimäre Rezeptoren durch Verbindung und Expression von DNS |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US5266480A (en) | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
EP0436597B1 (de) | 1988-09-02 | 1997-04-02 | Protein Engineering Corporation | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
KR900702061A (ko) | 1988-09-06 | 1990-12-05 | 원본미기재 | 구리를 용융시키는 방법 및 버어너 |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5198346A (en) | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
US5096815A (en) | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
WO1991000906A1 (en) | 1989-07-12 | 1991-01-24 | Genetics Institute, Inc. | Chimeric and transgenic animals capable of producing human antibodies |
AU6886791A (en) | 1989-11-13 | 1991-06-13 | Affymax Technologies N.V. | Spatially-addressable immobilization of anti-ligands on surfaces |
AU7163091A (en) * | 1989-12-12 | 1991-07-18 | Biomedical Research Institute | Novel malarial sporozoite peptide antigens |
WO1991010741A1 (en) | 1990-01-12 | 1991-07-25 | Cell Genesys, Inc. | Generation of xenogeneic antibodies |
US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
AU665190B2 (en) | 1990-07-10 | 1995-12-21 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
CA2089661C (en) | 1990-08-29 | 2007-04-03 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
US5612205A (en) | 1990-08-29 | 1997-03-18 | Genpharm International, Incorporated | Homologous recombination in mammalian cells |
US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
DE69129154T2 (de) | 1990-12-03 | 1998-08-20 | Genentech, Inc., South San Francisco, Calif. | Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften |
EP0562025B1 (de) | 1990-12-06 | 2001-02-07 | Affymetrix, Inc. (a Delaware Corporation) | Verbindungen und ihre Verwendung in einer binären Synthesestrategie |
ATE439435T1 (de) | 1991-03-01 | 2009-08-15 | Dyax Corp | Chimäres protein mit mikroprotein mit zwei oder mehr disulfidbindungen und ausgestaltungen davon |
DE69233367T2 (de) | 1991-04-10 | 2005-05-25 | The Scripps Research Institute, La Jolla | Bibliotheken heterodimerer rezeptoren mittels phagemiden |
DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
US5677195A (en) | 1991-11-22 | 1997-10-14 | Affymax Technologies N.V. | Combinatorial strategies for polymer synthesis |
US5233409A (en) | 1992-02-25 | 1993-08-03 | Schwab Karl W | Color analysis of organic constituents in sedimentary rocks for thermal maturity |
US5359115A (en) | 1992-03-26 | 1994-10-25 | Affymax Technologies, N.V. | Methods for the synthesis of phosphonate esters |
US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
US5288514A (en) | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
ES2204910T3 (es) | 1992-10-01 | 2004-05-01 | The Trustees Of Columbia University In The City Of New York | Bibliotecas quimicas combinatorias complejas codificadas con señales. |
US6174530B1 (en) | 1993-05-05 | 2001-01-16 | Gryphon Sciences | Homogeneous polyoxime compositions and their preparation by parallel assembly |
CA2163345A1 (en) | 1993-06-16 | 1994-12-22 | Susan Adrienne Morgan | Antibodies |
US5362899A (en) | 1993-09-09 | 1994-11-08 | Affymax Technologies, N.V. | Chiral synthesis of alpha-aminophosponic acids |
US6184344B1 (en) | 1995-05-04 | 2001-02-06 | The Scripps Research Institute | Synthesis of proteins by native chemical ligation |
US6376653B1 (en) | 1998-09-28 | 2002-04-23 | Smithkline Beecham Plc | Tie2 antagonist antibodies |
WO2001088088A2 (en) * | 2000-05-18 | 2001-11-22 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
AU774841B2 (en) * | 1998-12-03 | 2004-07-08 | Targanta Therapeutics Inc. | Development of novel anti-microbial agents based on bacteriophage genomics |
AU2407600A (en) * | 1999-01-15 | 2000-08-01 | Craig S. Echt | Microsatellite dna markers and uses thereof |
US6753314B1 (en) * | 1999-04-01 | 2004-06-22 | Curagen Corporation | Protein-protein complexes and methods of using same |
US6355481B1 (en) * | 1999-06-18 | 2002-03-12 | Emory University | Hybridoma cell line and monoclonal antibody for huntingtin protein |
AU2001238347A1 (en) * | 2000-02-28 | 2001-09-12 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
WO2001093892A1 (en) * | 2000-06-08 | 2001-12-13 | The Center For Blood Research, Inc. | Methods and compositions for inhibiting immunoglobulin-mediated__reperfusion injury |
EP2113516B1 (de) * | 2000-10-10 | 2014-05-21 | Genentech, Inc. | C5 Antikörper, die die Typ II Aktivierung von Endothelialzellen inhibieren |
WO2002096948A2 (en) * | 2001-01-29 | 2002-12-05 | Idec Pharmaceuticals Corporation | Engineered tetravalent antibodies and methods of use |
US20040131607A1 (en) | 2001-06-08 | 2004-07-08 | Carroll Michael C. | Methods and compositions for inhibiting immunoglobulin-mediated reperfusion injury |
AU2002357382A1 (en) * | 2001-12-21 | 2003-07-30 | Diadexus, Inc. | Compositions and methods relating to endometrial specific genes and proteins |
AU2002364105A1 (en) * | 2001-12-21 | 2003-07-15 | Diadexus, Inc. | Compositions and methods relating to endometrial specific genes and proteins |
US7709610B2 (en) * | 2003-05-08 | 2010-05-04 | Facet Biotech Corporation | Therapeutic use of anti-CS1 antibodies |
US20100136684A1 (en) | 2004-03-01 | 2010-06-03 | Carroll Michael C | Natural IgM Antibodies |
ATE498010T1 (de) | 2004-03-01 | 2011-02-15 | Immune Disease Inst Inc | Natürliche igm-antikörper und inhibitoren davon |
US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
IT1395574B1 (it) | 2009-09-14 | 2012-10-16 | Guala Dispensing Spa | Dispositivo di erogazione |
-
2005
- 2005-03-01 AT AT05723931T patent/ATE498010T1/de not_active IP Right Cessation
- 2005-03-01 WO PCT/US2005/006276 patent/WO2005085288A2/en active Application Filing
- 2005-03-01 JP JP2007501869A patent/JP5557982B2/ja not_active Expired - Fee Related
- 2005-03-01 CA CA002560066A patent/CA2560066A1/en not_active Abandoned
- 2005-03-01 EP EP05723931A patent/EP1725659B1/de not_active Not-in-force
- 2005-03-01 AU AU2005219839A patent/AU2005219839B9/en not_active Ceased
- 2005-03-01 EP EP10185693.8A patent/EP2290077B1/de not_active Not-in-force
- 2005-03-01 US US11/069,834 patent/US7442783B2/en active Active
- 2005-03-01 DE DE602005026260T patent/DE602005026260D1/de active Active
-
2006
- 2006-08-31 IL IL177825A patent/IL177825A/en not_active IP Right Cessation
-
2008
- 2008-10-28 US US12/259,767 patent/US20090176966A1/en not_active Abandoned
-
2011
- 2011-02-01 JP JP2011019668A patent/JP5618852B2/ja not_active Expired - Fee Related
- 2011-09-01 HK HK11109256.7A patent/HK1154904A1/zh not_active IP Right Cessation
-
2013
- 2013-04-09 US US13/859,054 patent/US9657060B2/en active Active
-
2014
- 2014-04-24 JP JP2014089965A patent/JP2014155497A/ja active Pending
-
2015
- 2015-07-23 US US14/806,924 patent/US9914751B2/en active Active
-
2017
- 2017-05-08 US US15/588,933 patent/US20170342109A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP5557982B2 (ja) | 2014-07-23 |
US20090176966A1 (en) | 2009-07-09 |
HK1154904A1 (zh) | 2012-05-04 |
US20170342109A1 (en) | 2017-11-30 |
US20050276811A1 (en) | 2005-12-15 |
EP2290077A2 (de) | 2011-03-02 |
JP2014155497A (ja) | 2014-08-28 |
EP2290077B1 (de) | 2016-01-27 |
US9657060B2 (en) | 2017-05-23 |
EP2290077A3 (de) | 2011-05-18 |
AU2005219839A1 (en) | 2005-09-15 |
AU2005219839B9 (en) | 2011-12-22 |
EP1725659A2 (de) | 2006-11-29 |
JP2011139704A (ja) | 2011-07-21 |
US9914751B2 (en) | 2018-03-13 |
ATE498010T1 (de) | 2011-02-15 |
WO2005085288A2 (en) | 2005-09-15 |
WO2005085288A3 (en) | 2006-08-03 |
CA2560066A1 (en) | 2005-09-15 |
US20160280740A1 (en) | 2016-09-29 |
IL177825A0 (en) | 2006-12-31 |
EP1725659B1 (de) | 2011-02-09 |
AU2005219839B2 (en) | 2011-11-24 |
US20140127214A1 (en) | 2014-05-08 |
US7442783B2 (en) | 2008-10-28 |
JP2008504807A (ja) | 2008-02-21 |
IL177825A (en) | 2013-02-28 |
JP5618852B2 (ja) | 2014-11-05 |
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