NO20074563L - Novel anti-plgf antibody - Google Patents

Novel anti-plgf antibody

Info

Publication number
NO20074563L
NO20074563L NO20074563A NO20074563A NO20074563L NO 20074563 L NO20074563 L NO 20074563L NO 20074563 A NO20074563 A NO 20074563A NO 20074563 A NO20074563 A NO 20074563A NO 20074563 L NO20074563 L NO 20074563L
Authority
NO
Norway
Prior art keywords
novel anti
plgf antibody
fragments
plgf
antibody
Prior art date
Application number
NO20074563A
Other languages
English (en)
Other versions
NO341877B1 (no
Inventor
Desire Jose Collen
Jean-Marie Stassen
Peter Carmeliet
Original Assignee
Thrombogenics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombogenics Nv filed Critical Thrombogenics Nv
Publication of NO20074563L publication Critical patent/NO20074563L/no
Publication of NO341877B1 publication Critical patent/NO341877B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Abstract

Sammendrag Foreliggende oppfinnelse angår nye antistoffer og fragmenter og derivater derav, særlig egnet for inhiberingen av angiogenese ved patologiske tilstander.
NO20074563A 2005-03-24 2007-09-10 Nytt anti-plgf antistoff NO341877B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66476805P 2005-03-24 2005-03-24
PCT/BE2006/000023 WO2006099698A2 (en) 2005-03-24 2006-03-24 Novel anti-plgf antibody

Publications (2)

Publication Number Publication Date
NO20074563L true NO20074563L (no) 2007-12-18
NO341877B1 NO341877B1 (no) 2018-02-12

Family

ID=36928446

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074563A NO341877B1 (no) 2005-03-24 2007-09-10 Nytt anti-plgf antistoff

Country Status (27)

Country Link
US (3) US7875704B2 (no)
EP (2) EP2447281B1 (no)
JP (2) JP5164829B2 (no)
KR (1) KR101314014B1 (no)
CN (1) CN101184776B (no)
AT (1) ATE549358T1 (no)
AU (2) AU2006227571B8 (no)
BR (1) BRPI0609151B8 (no)
CA (1) CA2601267C (no)
CY (1) CY1113224T1 (no)
DK (1) DK1869085T3 (no)
EA (1) EA013970B1 (no)
ES (2) ES2565481T3 (no)
HK (1) HK1116803A1 (no)
HR (1) HRP20120477T1 (no)
IL (1) IL185754A (no)
ME (1) ME01446B (no)
MX (1) MX2007011735A (no)
NO (1) NO341877B1 (no)
NZ (1) NZ561763A (no)
PL (1) PL1869085T3 (no)
PT (1) PT1869085E (no)
RS (1) RS52372B (no)
SI (1) SI1869085T1 (no)
UA (1) UA94707C2 (no)
WO (1) WO2006099698A2 (no)
ZA (1) ZA200707258B (no)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2260234T3 (es) * 2000-05-12 2006-11-01 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. Utilizacion de inhibidores del factor de crecimiento placentario para el tratamiento de la angiogenesis patologica, de la arteriogenesis patologica, de la inflamacion, de la formacion tumoral y/o de la perdida vascular.
PT1869085E (pt) 2005-03-24 2012-06-01 Vlaams Interuniv Inst Biotech Vzw Novo anticorpo anti-plgf
CN101534865A (zh) * 2005-10-19 2009-09-16 Ibc药品公司 生物活性装配体的制备方法及其用途
SG190572A1 (en) * 2008-04-29 2013-06-28 Abbott Lab Dual variable domain immunoglobulins and uses thereof
RU2010153578A (ru) 2008-06-03 2012-07-20 Эбботт Лэборетриз (Us) Иммуноглобулины с двойными вариабельными доменами и их применение
CA2726087A1 (en) 2008-06-03 2009-12-10 Tariq Ghayur Dual variable domain immunoglobulins and uses thereof
RU2011104348A (ru) 2008-07-08 2012-08-20 Эбботт Лэборетриз (Us) Иммуноглобулины с двойным вариабельным доменом против простагландина е2 и их применение
MX2011003428A (es) 2008-10-02 2011-07-29 Vib Vzw Inhibicion del factor de crecimiento placentario (plgf) para tratar la leucemia con cromosoma filadelfia positivo.
KR101596539B1 (ko) * 2008-12-23 2016-02-22 제넨테크, 인크. 암 환자에서의 진단 목적용 방법 및 조성물
RU2011148918A (ru) * 2009-05-01 2013-06-10 Эбботт Лэборетриз Иммуноглобулин с двумя вариабельными доменами и его применение
KR20120060877A (ko) 2009-09-01 2012-06-12 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
AU2010306677B2 (en) 2009-10-15 2013-05-23 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
KR101555740B1 (ko) 2010-03-10 2015-09-25 에프. 호프만-라 로슈 아게 면역글로불린 용액 정제 방법
EP2596364B1 (en) * 2010-07-19 2015-12-16 F.Hoffmann-La Roche Ag Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer
KR20130100118A (ko) 2010-08-03 2013-09-09 아비에 인코포레이티드 이원 가변 도메인 면역글로불린 및 이의 용도
CA2809433A1 (en) 2010-08-26 2012-03-01 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
WO2013079713A1 (en) 2011-12-01 2013-06-06 Thrombogenics Nv Improving trabeculectomy outcome
TW201333035A (zh) 2011-12-30 2013-08-16 Abbvie Inc 針對ｉｌ－１３及／或ｉｌ－１７之雙特異性結合蛋白
CA2890263C (en) 2012-11-01 2020-03-10 Abbvie Inc. Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
CN108641002A (zh) 2012-12-18 2018-10-12 西奈山伊坎医学院 流感病毒疫苗及其用途
WO2014159960A1 (en) 2013-03-14 2014-10-02 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
WO2014144280A2 (en) 2013-03-15 2014-09-18 Abbvie Inc. DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1β AND / OR IL-17
WO2015051159A1 (en) * 2013-10-02 2015-04-09 The Rockefeller University Amyloid protofibril antibodies and methods of use thereof
US10093733B2 (en) 2014-12-11 2018-10-09 Abbvie Inc. LRP-8 binding dual variable domain immunoglobulin proteins
US10736956B2 (en) 2015-01-23 2020-08-11 Icahn School Of Medicine At Mount Sinai Influenza virus vaccination regimens
TW201710286A (zh) 2015-06-15 2017-03-16 艾伯維有限公司 抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
CN104930353B (zh) * 2015-07-10 2017-08-15 浙江大学 一种城市供水管网的调压减漏评估系统
WO2017153567A1 (en) 2016-03-10 2017-09-14 Thrombogenics Nv Posterior ocular fibrosis inhibition by antagonizing placental growth factor
JP7237344B2 (ja) 2016-06-15 2023-03-13 アイカーン スクール オブ メディシン アット マウント サイナイ インフルエンザウイルス血球凝集素タンパク質及びその使用
CA3058652A1 (en) * 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
CN109134650A (zh) * 2018-09-10 2019-01-04 宁波奥丞生物科技有限公司 抗人plgf单克隆抗体的制备方法
WO2020239934A1 (en) 2019-05-28 2020-12-03 Vib Vzw Cd8+ t-cells lacking plexins and their application in cancer treatment
EP3976650A1 (en) 2019-05-28 2022-04-06 Vib Vzw Cancer treatment by targeting plexins in the immune compartment
WO2020260595A1 (en) 2019-06-26 2020-12-30 Oncurious Nv Combination treatment of medulloblastoma using a placental growth factor inhibitor and a chemotherapeutic agent
EP3936868A1 (en) 2020-07-10 2022-01-12 Charité - Universitätsmedizin Berlin A ratio between plgf and sflt1 is predictive for neural invasion in patients suffering from pancreatic cancer
WO2022063957A1 (en) 2020-09-24 2022-03-31 Vib Vzw Biomarker for anti-tumor therapy
WO2022099465A1 (zh) * 2020-11-10 2022-05-19 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其制备方法和应用
CN112358546B (zh) * 2020-11-10 2022-04-01 宁波奥丞生物科技有限公司 杂交瘤细胞株9c1、plgf-1单克隆抗体及其应用
CA3203072A1 (en) 2020-12-22 2022-06-30 Andrea CASAZZA Compounds comprising a tetrapeptidic moiety
CN113999310A (zh) * 2020-12-30 2022-02-01 江苏普若维生物技术有限责任公司 一种plgf单克隆抗体、试剂盒、其制备方法和应用
WO2022167664A1 (en) 2021-02-07 2022-08-11 Cobiores Nv Compounds comprising a tetrapeptidic moiety
WO2022175392A1 (en) 2021-02-17 2022-08-25 Vib Vzw Inhibition of slc4a4 in the treatment of cancer
WO2023118294A1 (en) 2021-12-22 2023-06-29 Vib Vzw Inhibition of mitoferrin 2 as means for inhibiting cancer and cancer metastasis
WO2024033381A1 (en) 2022-08-10 2024-02-15 Vib Vzw Inhibition of tcf4/itf2 in the treatment of cancer

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US5770198A (en) 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
IT1242149B (it) 1990-09-27 1994-02-16 Consiglio Nazionale Ricerche Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
US5578704A (en) * 1992-04-03 1996-11-26 Genentech, Inc. Antibody to osteoclast alphavbeta3 ntegrin
US6177401B1 (en) 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
US5861499A (en) * 1994-02-10 1999-01-19 Imclone Systems Incorporated Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
MY134778A (en) 1995-10-23 2007-12-31 Hyal Pharmaceutical Australia Ltd Hyaluronic acid as dna carrier for gene therapy and vegf antisense dna to treat abnormal retinal vascularization
JP2001501471A (ja) 1996-09-24 2001-02-06 メルク エンド カンパニー インコーポレーテッド 血管新生の阻害のための遺伝子治療
US6986890B1 (en) * 1996-11-21 2006-01-17 Kyowa Hakko Kogyo Co., Ltd. Anti-human VEGF receptor Flt-1 monoclonal antibody
GB9723780D0 (en) 1997-11-12 1998-01-07 Univ Manchester Regulation of ocular angiogenesis
EP1064382B1 (en) * 1998-03-17 2008-08-20 Genentech, Inc. Polypeptides homologous to vegf and bmp1
JPH11302193A (ja) * 1998-04-22 1999-11-02 Toagosei Co Ltd 血管新生阻害剤
WO1999060846A1 (en) 1998-05-26 1999-12-02 Innogenetics N.V. Method for expanding primate b cells selectively in immunocompromised mice and producing large numbers of antigen-specific b lymphocytes for the production of primate monoclonal antibodies
JP2001086982A (ja) 1999-07-16 2001-04-03 Shunpei Niida 骨吸収調節薬
CA2399022A1 (en) * 2000-02-04 2001-08-09 Supratek Pharma Inc. Ligand for vascular endothelial growth factor receptor
ES2260234T3 (es) * 2000-05-12 2006-11-01 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. Utilizacion de inhibidores del factor de crecimiento placentario para el tratamiento de la angiogenesis patologica, de la arteriogenesis patologica, de la inflamacion, de la formacion tumoral y/o de la perdida vascular.
US8021658B2 (en) * 2001-05-25 2011-09-20 Thomas Jefferson University Alternative splice forms of proteins as basis for multiple therapeutic modalities
US7139817B1 (en) * 2001-06-12 2006-11-21 Network Appliance, Inc. Managing configuration information for multiple devices
JP2005508298A (ja) 2001-06-20 2005-03-31 イムクローン システムズ インコーポレイティド アテローム性動脈硬化症及び他の炎症性疾患を処置する方法
ATE347908T1 (de) 2002-01-29 2007-01-15 Vlaams Interuniv Inst Biotech Vorbeugung von gewebeadhäsion
IL165392A0 (en) 2002-06-05 2006-01-15 Genentech Inc Compositions and methods for liver growth and liver protection
AU2003251729A1 (en) 2002-06-28 2004-01-19 K.U.Leuven Research & Development Use of antibodies against flt-1 for the treatment of osteoporosis
WO2004042085A2 (en) * 2002-11-08 2004-05-21 Primagen Holding B.V. Method for quantifying a ratio between at least two nucleic acid sequences
WO2004080408A2 (en) * 2003-03-10 2004-09-23 Callisto Pharmaceuticals, Inc. Method of treating cancer with azaspirane compositions
US20050282233A1 (en) * 2004-03-05 2005-12-22 Ludwig Institute For Cancer Research Multivalent antibody materials and methods for VEGF/PDGF family of growth factors
PT1869085E (pt) * 2005-03-24 2012-06-01 Vlaams Interuniv Inst Biotech Vzw Novo anticorpo anti-plgf
US7867490B2 (en) * 2005-06-30 2011-01-11 Vib Vzw Treatment of liver cirrhosis and its complications
MX2011003428A (es) 2008-10-02 2011-07-29 Vib Vzw Inhibicion del factor de crecimiento placentario (plgf) para tratar la leucemia con cromosoma filadelfia positivo.

Also Published As

Publication number Publication date
AU2006227571B8 (en) 2011-01-27
AU2011201340B2 (en) 2012-02-23
ATE549358T1 (de) 2012-03-15
EP1869085B1 (en) 2012-03-14
ES2384110T3 (es) 2012-06-29
CN101184776A (zh) 2008-05-21
EA013970B1 (ru) 2010-08-30
US7875704B2 (en) 2011-01-25
DK1869085T3 (da) 2012-06-18
NO341877B1 (no) 2018-02-12
HRP20120477T1 (hr) 2012-07-31
AU2011201340A1 (en) 2011-04-14
BRPI0609151B1 (pt) 2020-01-21
EP2447281A1 (en) 2012-05-02
ZA200707258B (en) 2008-06-25
EP2447281B1 (en) 2015-12-16
AU2006227571B2 (en) 2010-12-23
JP2012136522A (ja) 2012-07-19
UA94707C2 (en) 2011-06-10
SI1869085T1 (sl) 2012-07-31
US20140178397A1 (en) 2014-06-26
WO2006099698A3 (en) 2006-11-30
MX2007011735A (es) 2008-03-14
RS52372B (en) 2012-12-31
EA200702064A1 (ru) 2008-02-28
PL1869085T3 (pl) 2012-09-28
CN101184776B (zh) 2013-04-24
IL185754A (en) 2013-02-28
US20080193455A1 (en) 2008-08-14
NZ561763A (en) 2009-02-28
EP1869085A2 (en) 2007-12-26
CA2601267A1 (en) 2006-09-28
BRPI0609151A2 (pt) 2010-02-17
KR101314014B1 (ko) 2013-10-02
CA2601267C (en) 2014-02-18
US20110123525A1 (en) 2011-05-26
KR20080016794A (ko) 2008-02-22
AU2006227571A1 (en) 2006-09-28
CY1113224T1 (el) 2016-04-13
US9085617B2 (en) 2015-07-21
WO2006099698A2 (en) 2006-09-28
JP2008532557A (ja) 2008-08-21
HK1116803A1 (en) 2009-01-02
US8758748B2 (en) 2014-06-24
ME01446B (me) 2013-12-20
PT1869085E (pt) 2012-06-01
BRPI0609151B8 (pt) 2021-05-25
ES2565481T3 (es) 2016-04-05
JP5164829B2 (ja) 2013-03-21
IL185754A0 (en) 2008-01-06

Similar Documents

Publication Publication Date Title
NO20074563L (no) Novel anti-plgf antibody
LTC2567976I2 (lt) Antikūnai prieš CD38 antigeną, skirti išsėtinės mielomos gydymui
CY1120365T1 (el) Αντισωματα εναντι της il-17
NL301089I2 (nl) imlifidase
DE602006013029D1 (de) Anti-egfr-antikörper
UA92504C2 (en) Anti-myostatin monoclonal antibody
EA200802168A1 (ru) Гуманизированное антитело к с-kit
ATE545657T1 (de) Tgf-beta antikörper
NO20084650L (no) Modifiserte humaniserte anti-interleukin-18 antistoffer
ATE502052T1 (de) Monoklonale antikörper gegen den humanen anti- müllerian-hormonrezeptor vom typ ii (amhr-ii)
WO2005003169A3 (en) Modified antibody fab fragments
NO20076404L (no) Humaniserte anti-CD40 antistoffer og deres anvendelsesmetoder
NZ594466A (en) Human monoclonal antibodies to protein tyrosine kinase 7 (PTK7) and methods for using anti-PTK7 antibodies
TW200738748A (en) Human monoclonal antibody human CD134 (OX40) and methods of making and using same
WO2003034903A3 (en) Psma antibodies and protein multimers
DK3656793T3 (da) Monoklonale antistoffer mod claudin-18 til cancerbehandling
EA201170590A1 (ru) Ингибиторы рецептора фактора роста фибробластов-3 (fgfr-3) и способы лечения
EA201070636A1 (ru) Ингибирование рецептора белка, стимулирующего макрофаги (ron), и способы его лечения
DK2109623T3 (da) Cancerbehandling med anti-IL-1-antistoffer
DK1411962T3 (da) Terapi for pancreacancer med monoklonalt stof
ATE498010T1 (de) Natürliche igm-antikörper und inhibitoren davon
EA200702634A1 (ru) Гуманизированные антитела, специфичные в отношении nogo-a, и их фармацевтические применения
ITRM20040105A1 (it) Anticorpo monoclonale antitenascina umana.
UA98100C2 (ru) Гуманизированное моноклональное антитело, которое связывается с человеческим nogo и нейтрализует его
CY1115979T1 (el) Αντισωματα κατα της μυοστατινης

Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOT, BE

MM1K Lapsed by not paying the annual fees