NO20074563L - Novel anti-plgf antibody - Google Patents

Novel anti-plgf antibody

Info

Publication number
NO20074563L
NO20074563L NO20074563A NO20074563A NO20074563L NO 20074563 L NO20074563 L NO 20074563L NO 20074563 A NO20074563 A NO 20074563A NO 20074563 A NO20074563 A NO 20074563A NO 20074563 L NO20074563 L NO 20074563L
Authority
NO
Norway
Prior art keywords
novel anti
plgf antibody
fragments
plgf
antibody
Prior art date
Application number
NO20074563A
Other languages
Norwegian (no)
Other versions
NO341877B1 (en
Inventor
Desire Jose Collen
Jean-Marie Stassen
Peter Carmeliet
Original Assignee
Thrombogenics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombogenics Nv filed Critical Thrombogenics Nv
Publication of NO20074563L publication Critical patent/NO20074563L/en
Publication of NO341877B1 publication Critical patent/NO341877B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Abstract

The present invention provides novel monoclonal antibodies directed to PIGF and fragments and derivatives thereof, more particularly to humanized antibodies and fragments thereof for use in the treatment and/or prevention of pathological angiogenesis.
NO20074563A 2005-03-24 2007-09-10 NEW ANTI-PLGF ANTIBODY NO341877B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66476805P 2005-03-24 2005-03-24
PCT/BE2006/000023 WO2006099698A2 (en) 2005-03-24 2006-03-24 Novel anti-plgf antibody

Publications (2)

Publication Number Publication Date
NO20074563L true NO20074563L (en) 2007-12-18
NO341877B1 NO341877B1 (en) 2018-02-12

Family

ID=36928446

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074563A NO341877B1 (en) 2005-03-24 2007-09-10 NEW ANTI-PLGF ANTIBODY

Country Status (27)

Country Link
US (3) US7875704B2 (en)
EP (2) EP2447281B1 (en)
JP (2) JP5164829B2 (en)
KR (1) KR101314014B1 (en)
CN (1) CN101184776B (en)
AT (1) ATE549358T1 (en)
AU (2) AU2006227571B8 (en)
BR (1) BRPI0609151B8 (en)
CA (1) CA2601267C (en)
CY (1) CY1113224T1 (en)
DK (1) DK1869085T3 (en)
EA (1) EA013970B1 (en)
ES (2) ES2565481T3 (en)
HK (1) HK1116803A1 (en)
HR (1) HRP20120477T1 (en)
IL (1) IL185754A (en)
ME (1) ME01446B (en)
MX (1) MX2007011735A (en)
NO (1) NO341877B1 (en)
NZ (1) NZ561763A (en)
PL (1) PL1869085T3 (en)
PT (1) PT1869085E (en)
RS (1) RS52372B (en)
SI (1) SI1869085T1 (en)
UA (1) UA94707C2 (en)
WO (1) WO2006099698A2 (en)
ZA (1) ZA200707258B (en)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1297016B1 (en) * 2000-05-12 2006-03-22 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Use of inhibitors of placental growth factor for the treatment of pathological angiogenesis, pathological arteriogenesis, inflammation, tumour formation and/or vascular leakage
SI1869085T1 (en) 2005-03-24 2012-07-31 Thrombogenics Nv Novel anti-plgf antibody
CN101534865A (en) * 2005-10-19 2009-09-16 Ibc药品公司 Methods and compositions for generating bioactive assemblies of increased complexity and uses
EP2282769A4 (en) * 2008-04-29 2012-04-25 Abbott Lab Dual variable domain immunoglobulins and uses thereof
JP2011523853A (en) 2008-06-03 2011-08-25 アボット・ラボラトリーズ Dual variable domain immunoglobulins and uses thereof
KR20110016959A (en) 2008-06-03 2011-02-18 아보트 러보러터리즈 Dual variable domain immunoglobulins and uses thereof
SG192489A1 (en) 2008-07-08 2013-08-30 Abbott Lab Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
CN102239178B (en) 2008-10-02 2017-06-23 Vib研究所 Suppress PlGF to treat Philadelphia Chromosome Positive leukaemia
SG172355A1 (en) * 2008-12-23 2011-07-28 Genentech Inc Methods and compositions for diagnostic use in cancer patients
MX2011011670A (en) * 2009-05-01 2011-11-18 Abbott Lab Dual variable domain immunoglobulins and uses thereof.
SG178602A1 (en) 2009-09-01 2012-04-27 Abbott Lab Dual variable domain immunoglobulins and uses thereof
BR112012008833A2 (en) 2009-10-15 2015-09-08 Abbott Lab double variable domain immunoglobulins and uses thereof
UY32979A (en) 2009-10-28 2011-02-28 Abbott Lab IMMUNOGLOBULINS WITH DUAL VARIABLE DOMAIN AND USES OF THE SAME
WO2011110598A1 (en) 2010-03-10 2011-09-15 F. Hoffmann-La Roche Ag Method for purifying immunoglobulin solutions
SG187012A1 (en) * 2010-07-19 2013-02-28 Hoffmann La Roche Blood plasma biomarkers for bevacizumab combination therapies for treatment of pancreatic cancer
MX341579B (en) 2010-08-03 2016-08-25 Abbvie Inc * Dual variable domain immunoglobulins and uses thereof.
AU2011293253B2 (en) 2010-08-26 2014-12-11 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
PL2785739T3 (en) 2011-12-01 2017-10-31 Thrombogenics Nv Improving trabeculectomy outcome
CA2861610A1 (en) 2011-12-30 2013-07-04 Abbvie Inc. Dual specific binding proteins directed against il-13 and/or il-17
TW202210507A (en) 2012-11-01 2022-03-16 美商艾伯維有限公司 Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof
AU2013362935B2 (en) 2012-12-18 2018-10-04 Icahn School Of Medicine At Mount Sinai Influenza virus vaccines and uses thereof
US9908930B2 (en) 2013-03-14 2018-03-06 Icahn School Of Medicine At Mount Sinai Antibodies against influenza virus hemagglutinin and uses thereof
US9062108B2 (en) 2013-03-15 2015-06-23 Abbvie Inc. Dual specific binding proteins directed against IL-1 and/or IL-17
US10035847B2 (en) 2013-10-02 2018-07-31 The Rockefeller University Amyloid protofibril antibodies and methods of use thereof
US10093733B2 (en) 2014-12-11 2018-10-09 Abbvie Inc. LRP-8 binding dual variable domain immunoglobulin proteins
CA2974699A1 (en) 2015-01-23 2016-07-28 Icahn School Of Medicine At Mount Sinai Influenza virus vaccination regimens
TW201710286A (en) 2015-06-15 2017-03-16 艾伯維有限公司 Binding proteins against VEGF, PDGF, and/or their receptors
CN104930353B (en) * 2015-07-10 2017-08-15 浙江大学 A kind of pressure regulation of public supply mains subtracts leakage assessment system
US20190031762A1 (en) 2016-03-10 2019-01-31 Thrombogenics Nv Posterior ocular fibrosis inhibition by antagonizing placental growth factor
WO2017218624A1 (en) 2016-06-15 2017-12-21 Icahn School Of Medicine At Mount Sinai Influenza virus hemagglutinin proteins and uses thereof
CA3058652A1 (en) 2017-04-07 2018-10-11 Icahn School Of Medicine At Mount Sinai Anti-influenza b virus neuraminidase antibodies and uses thereof
CN109134650A (en) * 2018-09-10 2019-01-04 宁波奥丞生物科技有限公司 The preparation method of anti-human PLGF monoclonal antibody
WO2020239934A1 (en) 2019-05-28 2020-12-03 Vib Vzw Cd8+ t-cells lacking plexins and their application in cancer treatment
WO2020239945A1 (en) 2019-05-28 2020-12-03 Vib Vzw Cancer treatment by targeting plexins in the immune compartment
WO2020260595A1 (en) 2019-06-26 2020-12-30 Oncurious Nv Combination treatment of medulloblastoma using a placental growth factor inhibitor and a chemotherapeutic agent
EP3936868A1 (en) 2020-07-10 2022-01-12 Charité - Universitätsmedizin Berlin A ratio between plgf and sflt1 is predictive for neural invasion in patients suffering from pancreatic cancer
WO2022063957A1 (en) 2020-09-24 2022-03-31 Vib Vzw Biomarker for anti-tumor therapy
CN112358546B (en) * 2020-11-10 2022-04-01 宁波奥丞生物科技有限公司 Hybridoma cell strain 9C1, PLGF-1 monoclonal antibody and application thereof
WO2022099465A1 (en) * 2020-11-10 2022-05-19 宁波奥丞生物科技有限公司 Hybridoma cell strain 9c1, plgf-1 monoclonal antibody, preparation method therefor and application thereof
AU2021405744A1 (en) 2020-12-22 2023-08-03 Cobiores Nv Compounds comprising a tetrapeptidic moiety
CN113999310A (en) * 2020-12-30 2022-02-01 江苏普若维生物技术有限责任公司 PLGF monoclonal antibody, kit, preparation method and application thereof
WO2022167664A1 (en) 2021-02-07 2022-08-11 Cobiores Nv Compounds comprising a tetrapeptidic moiety
CN117241804A (en) 2021-02-17 2023-12-15 非营利性组织佛兰芒综合大学生物技术研究所 Inhibition of SLC4A4 in cancer treatment
WO2023118294A1 (en) 2021-12-22 2023-06-29 Vib Vzw Inhibition of mitoferrin 2 as means for inhibiting cancer and cancer metastasis
WO2024033381A1 (en) 2022-08-10 2024-02-15 Vib Vzw Inhibition of tcf4/itf2 in the treatment of cancer

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US5770198A (en) 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
IT1242149B (en) 1990-09-27 1994-02-16 Consiglio Nazionale Ricerche CODING NUCLEOTID SEQUENCE FOR A HUMAN PROTEIN WITH REGULATORY PROPERTIES OF ANGIOGENESIS
DE69322860T2 (en) * 1992-04-03 1999-07-01 Genentech Inc ANTIBODIES AGAINST ALPHA V BETA 3 INTEGRIN
US6177401B1 (en) 1992-11-13 2001-01-23 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis
US5861499A (en) * 1994-02-10 1999-01-19 Imclone Systems Incorporated Nucleic acid molecules encoding the variable or hypervariable region of a monoclonal antibody that binds to an extracellular domain
IL117645A (en) 1995-03-30 2005-08-31 Genentech Inc Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration
NZ320006A (en) 1995-10-23 2001-12-21 Meditech Res Ltd An adjuvant composition comprising hyaluronic acid for gene therapy either in the sense or antisense direction
DE69736860T2 (en) 1996-09-24 2007-05-16 Merck & Co., Inc. COMPOUNDS FOR INHIBITING ANGIOGENESIS THROUGH GENE THERAPY
US6986890B1 (en) * 1996-11-21 2006-01-17 Kyowa Hakko Kogyo Co., Ltd. Anti-human VEGF receptor Flt-1 monoclonal antibody
GB9723780D0 (en) 1997-11-12 1998-01-07 Univ Manchester Regulation of ocular angiogenesis
ES2389387T3 (en) * 1998-03-17 2012-10-25 Genentech, Inc. Homologous VEGF and BMP1 polypeptides
JPH11302193A (en) * 1998-04-22 1999-11-02 Toagosei Co Ltd Vascularization inhibitor
EP1079688A1 (en) 1998-05-26 2001-03-07 Innogenetics N.V. Method for expanding primate b cells selectively in immunocompromised mice and producing large numbers of antigen-specific b lymphocytes for the production of primate monoclonal antibodies
JP2001086982A (en) 1999-07-16 2001-04-03 Shunpei Niida Bone resorption regulator
AU2001228742A1 (en) * 2000-02-04 2001-08-14 Supratek Pharma, Inc. Ligand for vascular endothelial growth factor receptor
EP1297016B1 (en) * 2000-05-12 2006-03-22 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Use of inhibitors of placental growth factor for the treatment of pathological angiogenesis, pathological arteriogenesis, inflammation, tumour formation and/or vascular leakage
CN1511040A (en) * 2001-05-25 2004-07-07 ����˹���ѷ��ѧ Alternative splice forms of proteins as basis for multiple therapeutic modalities
US7139817B1 (en) * 2001-06-12 2006-11-21 Network Appliance, Inc. Managing configuration information for multiple devices
AU2002316305A1 (en) 2001-06-20 2003-01-08 Vlaams Interuniversitair Institut Voor Biotechnologie Method of treating atherosclerosis and other inflammatory diseases
WO2003063904A2 (en) 2002-01-29 2003-08-07 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Tissue adhesion formation control
IL165392A0 (en) 2002-06-05 2006-01-15 Genentech Inc Compositions and methods for liver growth and liver protection
ATE357255T1 (en) 2002-06-28 2007-04-15 Vlaams Interuniv Inst Biotech PLACENTA GROWTH FACTOR AS A TARGET FOR THE TREATMENT OF OSTEOPOROSIS
NZ540144A (en) * 2002-11-08 2008-08-29 Primagen Holding Bv Method for quantifying a ratio between at least two nucleic acid sequences
EP1610806A4 (en) * 2003-03-10 2006-04-19 Callisto Pharmaceuticals Inc Method of treating cancer with azaspirane compositions
WO2005087812A1 (en) * 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Multivalent antibody materials and methods for vegf/pdgf family of growth factors
SI1869085T1 (en) 2005-03-24 2012-07-31 Thrombogenics Nv Novel anti-plgf antibody
US7867490B2 (en) * 2005-06-30 2011-01-11 Vib Vzw Treatment of liver cirrhosis and its complications
CN102239178B (en) 2008-10-02 2017-06-23 Vib研究所 Suppress PlGF to treat Philadelphia Chromosome Positive leukaemia

Also Published As

Publication number Publication date
ATE549358T1 (en) 2012-03-15
ME01446B (en) 2013-12-20
CA2601267C (en) 2014-02-18
CN101184776B (en) 2013-04-24
JP2008532557A (en) 2008-08-21
ZA200707258B (en) 2008-06-25
EP1869085A2 (en) 2007-12-26
EA013970B1 (en) 2010-08-30
US20140178397A1 (en) 2014-06-26
WO2006099698A3 (en) 2006-11-30
PL1869085T3 (en) 2012-09-28
AU2006227571B2 (en) 2010-12-23
EP2447281B1 (en) 2015-12-16
WO2006099698A2 (en) 2006-09-28
IL185754A0 (en) 2008-01-06
ES2565481T3 (en) 2016-04-05
AU2006227571A1 (en) 2006-09-28
AU2011201340B2 (en) 2012-02-23
PT1869085E (en) 2012-06-01
BRPI0609151A2 (en) 2010-02-17
EA200702064A1 (en) 2008-02-28
BRPI0609151B1 (en) 2020-01-21
BRPI0609151B8 (en) 2021-05-25
MX2007011735A (en) 2008-03-14
HK1116803A1 (en) 2009-01-02
JP5164829B2 (en) 2013-03-21
US8758748B2 (en) 2014-06-24
KR101314014B1 (en) 2013-10-02
CY1113224T1 (en) 2016-04-13
EP1869085B1 (en) 2012-03-14
RS52372B (en) 2012-12-31
DK1869085T3 (en) 2012-06-18
UA94707C2 (en) 2011-06-10
EP2447281A1 (en) 2012-05-02
US7875704B2 (en) 2011-01-25
US20110123525A1 (en) 2011-05-26
NZ561763A (en) 2009-02-28
HRP20120477T1 (en) 2012-07-31
CN101184776A (en) 2008-05-21
IL185754A (en) 2013-02-28
US9085617B2 (en) 2015-07-21
JP2012136522A (en) 2012-07-19
KR20080016794A (en) 2008-02-22
AU2011201340A1 (en) 2011-04-14
SI1869085T1 (en) 2012-07-31
NO341877B1 (en) 2018-02-12
AU2006227571B8 (en) 2011-01-27
ES2384110T3 (en) 2012-06-29
CA2601267A1 (en) 2006-09-28
US20080193455A1 (en) 2008-08-14

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