NO20076404L - Humaniserte anti-CD40 antistoffer og deres anvendelsesmetoder - Google Patents
Humaniserte anti-CD40 antistoffer og deres anvendelsesmetoderInfo
- Publication number
- NO20076404L NO20076404L NO20076404A NO20076404A NO20076404L NO 20076404 L NO20076404 L NO 20076404L NO 20076404 A NO20076404 A NO 20076404A NO 20076404 A NO20076404 A NO 20076404A NO 20076404 L NO20076404 L NO 20076404L
- Authority
- NO
- Norway
- Prior art keywords
- antibodies
- methods
- humanized anti
- antigen
- expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Sammendrag Tilveiebrakt er humaniserte anti-CD40-antistoffer og antigen-bindende fragmenter og fremgangsmåter for behandling av sykdom kjennetegnet ved ekspresjon av CD40antigen.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68485305P | 2005-05-26 | 2005-05-26 | |
PCT/US2006/020688 WO2006128103A2 (en) | 2005-05-26 | 2006-05-26 | Humanized anti-cd40 antibodies and their methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20076404L true NO20076404L (no) | 2008-02-13 |
NO341793B1 NO341793B1 (no) | 2018-01-22 |
Family
ID=37452957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20076404A NO341793B1 (no) | 2005-05-26 | 2007-12-12 | Humaniserte anti-CD40 antistoffer eller antigenbindende fragment, farmasøytisk sammensetning, isolert polynukleotid og kit |
Country Status (19)
Country | Link |
---|---|
US (4) | US8303955B2 (no) |
EP (1) | EP1885399B1 (no) |
JP (1) | JP5027804B2 (no) |
KR (1) | KR100991010B1 (no) |
CN (1) | CN101237882B (no) |
AT (1) | ATE485057T1 (no) |
AU (1) | AU2006249305B2 (no) |
BR (1) | BRPI0610470A2 (no) |
CA (1) | CA2609269C (no) |
CR (1) | CR9562A (no) |
DE (1) | DE602006017690D1 (no) |
EC (1) | ECSP078026A (no) |
ES (1) | ES2354865T3 (no) |
IL (1) | IL187594A0 (no) |
MA (1) | MA29595B1 (no) |
NO (1) | NO341793B1 (no) |
PL (1) | PL1885399T3 (no) |
RU (1) | RU2407544C2 (no) |
WO (1) | WO2006128103A2 (no) |
Families Citing this family (73)
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US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
WO2006128103A2 (en) * | 2005-05-26 | 2006-11-30 | Seattle Genetics, Inc. | Humanized anti-cd40 antibodies and their methods of use |
BRPI0619586A2 (pt) * | 2005-12-09 | 2018-08-28 | Seattle Genetics Inc | método para o tratamento ou prevenção de um distúrbio associado com cd40 |
CA2669412A1 (en) * | 2007-01-23 | 2008-07-31 | Xencor, Inc. | Optimized cd40 antibodies and methods of using the same |
MX2010005080A (es) | 2007-11-07 | 2010-07-28 | Genentech Inc | Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40. |
FR2942799B1 (fr) * | 2009-03-06 | 2011-02-25 | Lfb Biotechnologies | Anticorps monoclonal anti-rhesus d |
CN102770457A (zh) | 2009-03-10 | 2012-11-07 | 贝勒研究院 | 靶向抗原呈递细胞的疫苗 |
BRPI1009455A2 (pt) | 2009-03-10 | 2016-03-01 | Baylor Res Inst | anticorpos anti-c40 e usos dos mesmos |
CN103415534A (zh) | 2009-03-10 | 2013-11-27 | 贝勒研究院 | 靶向抗原呈递细胞的癌症疫苗 |
CA2758523C (en) | 2009-04-18 | 2019-03-12 | Genentech, Inc. | Methods for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies |
WO2011084605A1 (en) * | 2009-12-16 | 2011-07-14 | The Trustees Of The University Of Pennsylvania | Anti-prostate cancer antibodies and methods of detection and treatment of prostate cancer using the same |
AR081750A1 (es) | 2010-03-31 | 2012-10-17 | Boehringer Ingelheim Int | Anticuerpos anti-cd40 |
CA2852056C (en) | 2011-03-11 | 2021-08-10 | Beth Israel Deaconess Medical Center, Inc. | Anti-cd40 antibodies and uses thereof |
EP2688592A4 (en) | 2011-03-25 | 2015-07-22 | Baylor Res Inst | COMPOSITIONS AND METHODS FOR IMMUNIZATION AGAINST HEPATITIS C VIRUS |
AU2012249454B2 (en) * | 2011-04-29 | 2016-03-24 | Apexigen, Inc. | Anti-CD40 antibodies and methods of use |
GB201115280D0 (en) | 2011-09-05 | 2011-10-19 | Alligator Bioscience Ab | Antibodies, uses and methods |
WO2013055745A2 (en) * | 2011-10-11 | 2013-04-18 | Medimmune, Llc | Cd40l-specific tn3-derived scaffolds and methods of use thereof |
AR090263A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
CN109265552A (zh) * | 2012-10-30 | 2019-01-25 | 埃派斯进有限公司 | 抗-cd40抗体及其使用方法 |
US9353150B2 (en) | 2012-12-04 | 2016-05-31 | Massachusetts Institute Of Technology | Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment |
AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
EP3992210A1 (en) | 2014-01-13 | 2022-05-04 | Baylor Research Institute | Novel vaccines against hpv and hpv-related diseases |
RU2749041C2 (ru) | 2014-04-30 | 2021-06-03 | Макс-Дельбрюк-Центрум Фюр Молекуляре Медицин Ин Дер Хельмхольтц - Гемайншафт | Гуманизированные антитела против cd269 (bcma) |
CA2957146A1 (en) | 2014-08-12 | 2016-02-18 | Alligator Bioscience Ab | Combination therapies with anti cd40 antibodies |
IL299075A (en) * | 2014-10-29 | 2023-02-01 | Seagen Inc | Dosage and administration of non-fucosylated anti-CD40 antibodies |
SG11201704058TA (en) * | 2014-11-18 | 2017-06-29 | Janssen Pharmaceutica Nv | Cd47 antibodies, methods, and uses |
EP3964527A3 (en) | 2015-04-13 | 2022-06-15 | Five Prime Therapeutics, Inc. | Combination therapy for cancer |
KR20180039172A (ko) * | 2015-09-01 | 2018-04-17 | 베링거 인겔하임 인터내셔날 게엠베하 | 루푸스 신염의 치료를 위한 항-cd40 항체의 용도 |
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MA43053A (fr) * | 2015-09-30 | 2018-08-08 | Janssen Biotech Inc | Anticorps antagonistes se liant spécifiquement au cd40 humain et procédés d'utilisation |
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US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
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BR112021003156A2 (pt) | 2018-08-23 | 2021-05-11 | Seagen, Inc. | composição, anticorpo que se liga ao tigit humano, formulação farmacêutica, polinucleotídeo isolado, vetor, célula hospedeira, métodos para a produção de um anticorpo que se liga ao tigit humano e de anticorpos afucosilados que se ligam a tigit e para o tratamento de um câncer, e, kit. |
JP2022511396A (ja) * | 2018-10-01 | 2022-01-31 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | Cd40への三価結合を伴う二重特異性抗原結合分子 |
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EP1263960A2 (en) | 2000-03-16 | 2002-12-11 | Genentech, Inc. | Anti-tissue factor antibodies with enhanced anticoagulant potency |
DK1341899T3 (da) * | 2000-12-14 | 2006-04-10 | Genentech Inc | Bakterieværtsstammer |
AU2004213053C1 (en) * | 2003-02-20 | 2009-07-16 | Seagen Inc. | Anti-CD70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders |
EP1697741A4 (en) | 2003-12-04 | 2008-02-13 | Xencor Inc | PROCESS FOR PRODUCING PROTEIN VARIANTS WITH INCREASED HOST STRUCTURE CONTENT AND COMPOSITIONS THEREOF |
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JP2008515774A (ja) * | 2004-08-03 | 2008-05-15 | ダイアックス コーポレイション | hK1結合タンパク質 |
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WO2006128103A2 (en) * | 2005-05-26 | 2006-11-30 | Seattle Genetics, Inc. | Humanized anti-cd40 antibodies and their methods of use |
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2006
- 2006-05-26 WO PCT/US2006/020688 patent/WO2006128103A2/en active Application Filing
- 2006-05-26 BR BRPI0610470-3A patent/BRPI0610470A2/pt not_active IP Right Cessation
- 2006-05-26 CA CA2609269A patent/CA2609269C/en active Active
- 2006-05-26 ES ES06771453T patent/ES2354865T3/es active Active
- 2006-05-26 DE DE602006017690T patent/DE602006017690D1/de active Active
- 2006-05-26 EP EP06771453A patent/EP1885399B1/en active Active
- 2006-05-26 AU AU2006249305A patent/AU2006249305B2/en active Active
- 2006-05-26 AT AT06771453T patent/ATE485057T1/de not_active IP Right Cessation
- 2006-05-26 US US11/913,305 patent/US8303955B2/en active Active
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- 2006-05-26 KR KR1020077030332A patent/KR100991010B1/ko active IP Right Grant
- 2006-05-26 CN CN2006800271172A patent/CN101237882B/zh active Active
- 2006-05-26 JP JP2008513805A patent/JP5027804B2/ja active Active
- 2006-05-26 PL PL06771453T patent/PL1885399T3/pl unknown
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- 2007-12-06 CR CR9562A patent/CR9562A/es not_active Application Discontinuation
- 2007-12-11 MA MA30474A patent/MA29595B1/fr unknown
- 2007-12-12 NO NO20076404A patent/NO341793B1/no unknown
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2012
- 2012-09-19 US US13/622,517 patent/US8492531B2/en active Active
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Also Published As
Publication number | Publication date |
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JP2008541733A (ja) | 2008-11-27 |
CA2609269A1 (en) | 2006-11-30 |
US20140193405A1 (en) | 2014-07-10 |
IL187594A0 (en) | 2008-03-20 |
RU2407544C2 (ru) | 2010-12-27 |
CN101237882A (zh) | 2008-08-06 |
AU2006249305B2 (en) | 2012-10-18 |
KR20080030958A (ko) | 2008-04-07 |
CN101237882B (zh) | 2012-08-15 |
NO341793B1 (no) | 2018-01-22 |
EP1885399A4 (en) | 2009-04-22 |
US20130315900A1 (en) | 2013-11-28 |
US8492531B2 (en) | 2013-07-23 |
ECSP078026A (es) | 2008-03-26 |
PL1885399T3 (pl) | 2011-04-29 |
DE602006017690D1 (de) | 2010-12-02 |
CR9562A (es) | 2008-03-06 |
MA29595B1 (fr) | 2008-07-01 |
US20090181015A1 (en) | 2009-07-16 |
EP1885399A2 (en) | 2008-02-13 |
RU2007148932A (ru) | 2009-07-10 |
AU2006249305A1 (en) | 2006-11-30 |
WO2006128103A3 (en) | 2007-01-18 |
ATE485057T1 (de) | 2010-11-15 |
US8303955B2 (en) | 2012-11-06 |
WO2006128103A2 (en) | 2006-11-30 |
EP1885399B1 (en) | 2010-10-20 |
BRPI0610470A2 (pt) | 2010-06-22 |
KR100991010B1 (ko) | 2010-10-29 |
US20130023047A1 (en) | 2013-01-24 |
ES2354865T3 (es) | 2011-03-18 |
CA2609269C (en) | 2014-08-05 |
JP5027804B2 (ja) | 2012-09-19 |
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