DK1341899T3 - Bakterieværtsstammer - Google Patents

Bakterieværtsstammer

Info

Publication number
DK1341899T3
DK1341899T3 DK01987349T DK01987349T DK1341899T3 DK 1341899 T3 DK1341899 T3 DK 1341899T3 DK 01987349 T DK01987349 T DK 01987349T DK 01987349 T DK01987349 T DK 01987349T DK 1341899 T3 DK1341899 T3 DK 1341899T3
Authority
DK
Denmark
Prior art keywords
prc
strain
bacterial host
host strains
degp
Prior art date
Application number
DK01987349T
Other languages
English (en)
Inventor
Christina Yu-Ching Chen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1341899T3 publication Critical patent/DK1341899T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK01987349T 2000-12-14 2001-12-07 Bakterieværtsstammer DK1341899T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25616200P 2000-12-14 2000-12-14

Publications (1)

Publication Number Publication Date
DK1341899T3 true DK1341899T3 (da) 2006-04-10

Family

ID=22971286

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01987349T DK1341899T3 (da) 2000-12-14 2001-12-07 Bakterieværtsstammer

Country Status (23)

Country Link
US (1) US6828121B2 (da)
EP (1) EP1341899B9 (da)
JP (1) JP4056880B2 (da)
KR (1) KR100841486B1 (da)
CN (1) CN1233820C (da)
AT (1) ATE318890T1 (da)
AU (2) AU3957602A (da)
BR (1) BR0116680A (da)
CA (1) CA2430249A1 (da)
CZ (1) CZ304484B6 (da)
DE (1) DE60117601T2 (da)
DK (1) DK1341899T3 (da)
ES (1) ES2259338T3 (da)
HK (1) HK1058686A1 (da)
HU (1) HU230065B1 (da)
IL (2) IL156111A0 (da)
MX (1) MXPA03005271A (da)
NO (1) NO328987B1 (da)
NZ (1) NZ526134A (da)
PL (1) PL205897B1 (da)
RU (1) RU2287574C2 (da)
WO (1) WO2002048376A2 (da)
ZA (1) ZA200304101B (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6979556B2 (en) * 2000-12-14 2005-12-27 Genentech, Inc. Separate-cistron contructs for secretion of aglycosylated antibodies from prokaryotes
WO2003018771A2 (en) 2001-08-27 2003-03-06 Genentech, Inc. A system for antibody expression and assembly
JP4050559B2 (ja) * 2002-06-28 2008-02-20 富士通株式会社 コンテンツ検索処理プログラム、コンテンツ検索処理プログラムを記録した記録媒体およびオペレータ問合せ処理システム
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
NZ568403A (en) * 2003-05-09 2009-10-30 Univ Duke CD20-specific antibodies and methods of employing same
AU2004282984B2 (en) 2003-11-13 2011-07-14 Hanmi Science Co., Ltd. Protein complex using immunoglobulin fragment andmethod for the preparation thereof
US8110665B2 (en) 2003-11-13 2012-02-07 Hanmi Holdings Co., Ltd. Pharmaceutical composition comprising an immunoglobulin FC region as a carrier
US8227241B2 (en) * 2004-03-12 2012-07-24 Unigene Laboratories, Inc. Bacterial host cell for the direct expression of peptides
EP2412816B1 (en) 2004-07-26 2014-12-03 Pfenex Inc. Process for improved protein expression by strain engineering
AU2006249305B2 (en) 2005-05-26 2012-10-18 Genentech, Inc. Humanized anti-CD40 antibodies and their methods of use
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
EP2142651B1 (en) 2007-04-27 2013-05-22 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
EP2176291A1 (en) * 2007-08-10 2010-04-21 Wacker Chemie AG Expression of full length igg and secretion into the culture medium of prokaryotic cells
PE20120622A1 (es) 2009-06-17 2012-05-26 Abbott Biotherapeutics Corp Anticuerpos anti-vegf y sus usos
KR101758942B1 (ko) * 2009-09-24 2017-07-17 유씨비 파마, 에스.에이. 박테리아 숙주 균주
WO2011036455A1 (en) 2009-09-24 2011-03-31 Ucb Pharma S.A. Bacterial strain for recombinant protein expression, having protease deficient degp retaining chaperone activity, and knocked out tsp and ptr genes
US8361744B2 (en) 2009-11-05 2013-01-29 Genentech, Inc. Methods and composition for secretion of heterologous polypeptides
GB201000587D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201000590D0 (en) * 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial host strain
GB201000591D0 (en) 2010-01-14 2010-03-03 Ucb Pharma Sa Bacterial hoist strain
GB201012599D0 (en) 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
EP3339325A1 (en) * 2011-07-13 2018-06-27 UCB Biopharma SPRL Bacterial host strain expressing recombinant dsbc
GB201208367D0 (en) 2012-05-14 2012-06-27 Ucb Pharma Sa Biological product
WO2014003709A1 (en) * 2012-06-25 2014-01-03 Empire Technology Development Llc Ultrasound based antigen binding detection
MX2015003028A (es) 2012-09-17 2015-06-10 Hoffmann La Roche Metodo para produccion de polipeptidos en periplasma de celulas procarioticas.
US20140154255A1 (en) 2012-11-30 2014-06-05 Abbvie Biotherapeutics Inc. Anti-vegf antibodies and their uses
ES2897765T3 (es) 2014-03-14 2022-03-02 Hoffmann La Roche Procedimientos y composiciones para la secreción de polipéptidos heterólogos
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
JP7033795B2 (ja) * 2017-02-22 2022-03-11 国立大学法人 長崎大学 生体由来材料の透明化用試薬
CN106967658B (zh) * 2017-02-23 2020-09-15 郑州大学 一种提高Fab抗体表达量的方法
CN108587992B (zh) * 2018-04-10 2022-03-15 安徽大学 一种高效分泌表达抗VEGF-Fab抗体片段的高产菌株及其构建方法
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
AU2020243460A1 (en) 2019-03-18 2021-10-07 Bio-Rad Abd Serotec Gmbh Protection of SpyTag-containing periplasmic fusion proteins from protease Tsp and ompT degradation
CN114829578A (zh) * 2019-08-05 2022-07-29 瓦克化学股份公司 用于在发酵方法中释放重组蛋白的细菌菌株
JPWO2021193566A1 (da) * 2020-03-23 2021-09-30
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
SE545714C2 (en) * 2021-09-24 2023-12-19 Xbrane Biopharma Ab Dna contructs for producing a pelb signal peptide
CA3232722A1 (en) 2021-09-24 2023-03-30 Kiavash MIRZADEH Dna constructs and host cells for expressing recombinant protein
SE545715C2 (en) * 2021-09-24 2023-12-19 Xbrane Biopharma Ab Dna contructs comprising tirs for producing recombinant proteins
SE545694C2 (en) * 2021-09-24 2023-12-05 Xbrane Biopharma Ab Dna construct comprising nucleotide sequences encoding amino acid sequences of certolizumab and pelb signal peptides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439523A (en) * 1981-07-07 1984-03-27 Phillips Petroleum Company Production of single cell protein material
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DE3853745D1 (de) 1987-01-30 1995-06-14 Harvard College Periplasmische protease-mutanten von escherichia coli.
CA1341235C (en) 1987-07-24 2001-05-22 Randy R. Robinson Modular assembly of antibody genes, antibodies prepared thereby and use
US5508192A (en) 1990-11-09 1996-04-16 Board Of Regents, The University Of Texas System Bacterial host strains for producing proteolytically sensitive polypeptides
US20020037558A1 (en) 1991-10-23 2002-03-28 Kin-Ming Lo E.coli produced immunoglobulin constructs
US6251395B1 (en) * 1993-12-23 2001-06-26 W. Michael Gallatin Methods of inhibiting inflammation at the site of a central nervous system injury with alphaD-specific antibodies
FR2787810B1 (fr) 1998-12-24 2002-10-31 Inst Nat De La Rech Agronomique Inra Bacteries a gram positif depourvues d'activite proteasique htra, et leurs utilisations

Also Published As

Publication number Publication date
BR0116680A (pt) 2005-04-05
AU2002239576B2 (en) 2007-03-29
KR100841486B1 (ko) 2008-06-25
IL156111A0 (en) 2003-12-23
MXPA03005271A (es) 2003-09-25
KR20030057579A (ko) 2003-07-04
CN1526010A (zh) 2004-09-01
ZA200304101B (en) 2005-07-27
WO2002048376A2 (en) 2002-06-20
ES2259338T3 (es) 2006-10-01
EP1341899B9 (en) 2007-03-21
NO328987B1 (no) 2010-07-12
RU2287574C2 (ru) 2006-11-20
AU3957602A (en) 2002-06-24
US6828121B2 (en) 2004-12-07
PL205897B1 (pl) 2010-06-30
JP4056880B2 (ja) 2008-03-05
DE60117601D1 (de) 2006-04-27
CZ304484B6 (cs) 2014-05-21
EP1341899A2 (en) 2003-09-10
HUP0303892A3 (en) 2011-03-28
CZ20031523A3 (cs) 2003-10-15
HK1058686A1 (en) 2004-05-28
JP2004537262A (ja) 2004-12-16
WO2002048376A3 (en) 2003-06-19
RU2003121232A (ru) 2005-01-20
PL366194A1 (en) 2005-01-24
ATE318890T1 (de) 2006-03-15
HUP0303892A2 (hu) 2004-03-01
EP1341899B1 (en) 2006-03-01
IL156111A (en) 2010-05-31
NO20032694L (no) 2003-08-14
US20020142388A1 (en) 2002-10-03
DE60117601T2 (de) 2006-11-16
CN1233820C (zh) 2005-12-28
NO20032694D0 (no) 2003-06-13
NZ526134A (en) 2005-07-29
HU230065B1 (hu) 2015-06-29
CA2430249A1 (en) 2002-06-20

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