AU2009256169A1 - Compositions and methods comprising variant microbial proteases - Google Patents

Compositions and methods comprising variant microbial proteases Download PDF

Info

Publication number
AU2009256169A1
AU2009256169A1 AU2009256169A AU2009256169A AU2009256169A1 AU 2009256169 A1 AU2009256169 A1 AU 2009256169A1 AU 2009256169 A AU2009256169 A AU 2009256169A AU 2009256169 A AU2009256169 A AU 2009256169A AU 2009256169 A1 AU2009256169 A1 AU 2009256169A1
Authority
AU
Australia
Prior art keywords
subtilisin
protease
variant
bpn
detergent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2009256169A
Other languages
English (en)
Inventor
Joshua R. Basler
Luis G. Cascao-Pereira
David A. Estell
James T. Kellis Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Danisco US Inc
Original Assignee
Danisco US Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco US Inc filed Critical Danisco US Inc
Publication of AU2009256169A1 publication Critical patent/AU2009256169A1/en
Priority to AU2014201929A priority Critical patent/AU2014201929A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38681Chemically modified or immobilised enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D2111/00Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
    • C11D2111/10Objects to be cleaned
    • C11D2111/12Soft surfaces, e.g. textile
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21062Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AU2009256169A 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases Abandoned AU2009256169A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014201929A AU2014201929A1 (en) 2008-06-06 2014-04-03 Compositions and methods comprising variant microbial proteases

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5969508P 2008-06-06 2008-06-06
US61/059,695 2008-06-06
PCT/US2009/046156 WO2009149200A2 (en) 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2014201929A Division AU2014201929A1 (en) 2008-06-06 2014-04-03 Compositions and methods comprising variant microbial proteases

Publications (1)

Publication Number Publication Date
AU2009256169A1 true AU2009256169A1 (en) 2009-12-10

Family

ID=41009802

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2009256295A Abandoned AU2009256295A1 (en) 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases
AU2009256169A Abandoned AU2009256169A1 (en) 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases
AU2009256294A Abandoned AU2009256294A1 (en) 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AU2009256295A Abandoned AU2009256295A1 (en) 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2009256294A Abandoned AU2009256294A1 (en) 2008-06-06 2009-06-03 Compositions and methods comprising variant microbial proteases

Country Status (13)

Country Link
US (12) US20110256610A1 (enExample)
EP (10) EP2297315A2 (enExample)
JP (8) JP6067221B2 (enExample)
KR (3) KR20110015006A (enExample)
CN (7) CN103382420B (enExample)
AU (3) AU2009256295A1 (enExample)
BR (3) BRPI0913623A8 (enExample)
CA (3) CA2726370A1 (enExample)
DK (2) DK2297314T3 (enExample)
MX (6) MX360255B (enExample)
RU (2) RU2010153866A (enExample)
WO (3) WO2009149145A2 (enExample)
ZA (1) ZA201008169B (enExample)

Families Citing this family (132)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2336092T3 (es) * 2002-01-16 2010-04-08 Genencor International, Inc. Variantes de proteasas con multiples sustituciones.
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
EP2297315A2 (en) * 2008-06-06 2011-03-23 Danisco US Inc. Compositions and methods comprising variant microbial proteases
EP2362896A2 (en) 2008-11-11 2011-09-07 Danisco US Inc. Bacillus subtilisin comprising one or more combinable mutations
EP2362897A2 (en) 2008-11-11 2011-09-07 Danisco US Inc. Compositions and methods comprising serine protease variants
MX2012000765A (es) * 2009-07-16 2012-02-13 Glaxo Group Ltd Dominios variables sencillos de union de albumina anti-suero mejorados.
BR112012006497A2 (pt) * 2009-09-25 2015-09-08 Novozymes As uso de uma variante de subtilisina, composição de lavagem de pratos, e, uso de uma composição.
CN105368809A (zh) 2009-12-09 2016-03-02 丹尼斯科美国公司 包含蛋白酶变体的组合物和方法
CN102652175B (zh) 2009-12-09 2016-02-10 宝洁公司 织物和家居护理产品
US20120067373A1 (en) * 2010-04-15 2012-03-22 Philip Frank Souter Automatic Dishwashing Detergent Composition
BR112012028467B1 (pt) * 2010-05-06 2021-02-17 Danisco Us Inc. variantes de subtilisina, seu método de produção, ácido nucleico, e método de limpeza
CA3194062A1 (en) * 2011-05-05 2012-11-08 Danisco Us Inc. Compositions and methods comprising serine protease variants
CN106065381B (zh) * 2011-05-05 2019-07-26 宝洁公司 包含丝氨酸蛋白酶变体的组合物和方法
EP2782988A1 (en) * 2011-11-25 2014-10-01 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2013092635A1 (en) * 2011-12-20 2013-06-27 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP2607468A1 (en) 2011-12-20 2013-06-26 Henkel AG & Co. KGaA Detergent compositions comprising subtilase variants
WO2013120948A1 (en) * 2012-02-17 2013-08-22 Novozymes A/S Subtilisin variants and polynucleotides encoding same
ES2582608T3 (es) * 2012-02-17 2016-09-14 Henkel Ag & Co. Kgaa Composiciones detergentes que comprenden variantes de subtilasa
WO2014099525A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Paenibacillus curdlanolyticus amylase, and methods of use, thereof
DK2935575T3 (en) 2012-12-21 2018-07-23 Danisco Us Inc ALPHA-amylase variants
DK2970931T3 (en) 2013-03-11 2018-01-22 Danisco Us Inc COMBINATORY ALPHA AMYLASE VARIATIONS
WO2014194034A2 (en) 2013-05-29 2014-12-04 Danisco Us Inc. Novel metalloproteases
US20160160202A1 (en) 2013-05-29 2016-06-09 Danisco Us Inc. Novel metalloproteases
EP3004341B1 (en) 2013-05-29 2017-08-30 Danisco US Inc. Novel metalloproteases
JP6367930B2 (ja) 2013-05-29 2018-08-01 ダニスコ・ユーエス・インク 新規メタロプロテアーゼ
WO2014207224A1 (en) 2013-06-27 2014-12-31 Novozymes A/S Subtilase variants and polynucleotides encoding same
EP3013950B1 (en) 2013-06-27 2018-08-08 Novozymes A/S Subtilase variants and polynucleotides encoding same
DK3044313T3 (da) * 2013-09-12 2020-02-17 Danisco Us Inc Sammensætninger og fremgangsmåder omfattende lg12-clade- proteasevarianter
US20160244699A1 (en) 2013-10-15 2016-08-25 Danisco Us Inc. Clay Granule
EP3068879B1 (en) 2013-11-14 2019-12-25 Danisco US Inc. Stable enzymes by glycation reduction
DK3080262T3 (da) 2013-12-13 2019-05-06 Danisco Us Inc Serinproteaser af bacillus-arter
WO2015089447A1 (en) 2013-12-13 2015-06-18 Danisco Us Inc. Serine proteases of the bacillus gibsonii-clade
EP4163305B1 (en) 2013-12-16 2024-07-10 Nutrition & Biosciences USA 4, Inc. Use of poly alpha-1,3-glucan ethers as viscosity modifiers
EP3083705B1 (en) 2013-12-18 2020-09-30 DuPont Industrial Biosciences USA, LLC Cationic poly alpha-1,3-glucan ethers
WO2015112338A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Method of treating textile fabrics
WO2015112340A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Method of treating textile fabrics
EP3097175B1 (en) 2014-01-22 2018-10-17 The Procter and Gamble Company Fabric treatment composition
WO2015112339A1 (en) 2014-01-22 2015-07-30 The Procter & Gamble Company Fabric treatment composition
US20150232785A1 (en) 2014-02-14 2015-08-20 E I Du Pont De Nemours And Company Polysaccharides for viscosity modification
JP2017515921A (ja) 2014-03-11 2017-06-15 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company 酸化されたポリα−1,3−グルカン
CN106170546A (zh) 2014-03-21 2016-11-30 丹尼斯科美国公司 芽孢杆菌属的丝氨酸蛋白酶
EP3919599A1 (en) 2014-06-19 2021-12-08 Nutrition & Biosciences USA 4, Inc. Compositions containing one or more poly alpha-1,3-glucan ether compounds
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
EP3164486B1 (en) 2014-07-04 2020-05-13 Novozymes A/S Subtilase variants and polynucleotides encoding same
US20170233710A1 (en) 2014-10-17 2017-08-17 Danisco Us Inc. Serine proteases of bacillus species
US20170306360A1 (en) 2014-10-24 2017-10-26 Danisco Us Inc. Method for producing alcohol by use of a tripeptidyl peptidase
WO2016069569A2 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
US20170335306A1 (en) 2014-10-27 2017-11-23 Danisco Us Inc. Serine proteases
EP3224357A1 (en) 2014-10-27 2017-10-04 Danisco US Inc. Serine proteases of bacillus species
EP4403631A3 (en) 2014-10-27 2024-10-30 Danisco US Inc. Serine proteases
DK3212662T3 (da) 2014-10-27 2020-07-20 Danisco Us Inc Serinproteaser
EP3256563A1 (en) 2014-11-17 2017-12-20 The Procter and Gamble Company Benefit agent delivery compositions
WO2016087617A1 (en) * 2014-12-04 2016-06-09 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2016087619A1 (en) 2014-12-04 2016-06-09 Novozymes A/S Liquid cleaning compositions comprising protease variants
EP3234122B1 (en) 2014-12-15 2020-10-14 Novozymes A/S Subtilase variants
US10400230B2 (en) * 2014-12-19 2019-09-03 Novozymes A/S Protease variants and polynucleotides encoding same
JP2018512109A (ja) 2014-12-23 2018-05-17 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーE.I.Du Pont De Nemours And Company 酵素により製造されるセルロース
US20180216090A1 (en) * 2015-03-12 2018-08-02 Danisco Us Inc. Compositions and methods comprising lg12-clade protease variants
US10513671B2 (en) 2015-04-29 2019-12-24 The Procter & Gamble Company Method of treating a fabric
EP3088505B1 (en) 2015-04-29 2020-06-03 The Procter and Gamble Company Method of treating a fabric
CN107820515A (zh) 2015-04-29 2018-03-20 宝洁公司 洗涤剂组合物
CN107548415A (zh) 2015-04-29 2018-01-05 宝洁公司 洗涤织物的方法
CN107532116B (zh) 2015-04-29 2021-05-07 宝洁公司 处理织物的方法
CN107835855B (zh) 2015-05-13 2022-05-13 丹尼斯科美国公司 AprL-进化枝蛋白酶变体及其用途
ES2962329T3 (es) 2015-06-09 2024-03-18 Danisco Us Inc Encapsulados de estallido osmótico
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
JP7015695B2 (ja) 2015-06-17 2022-02-03 ダニスコ・ユーエス・インク バチルス・ギブソニイ(Bacillus gibsonii)クレードセリンプロテアーゼ
JP7364330B2 (ja) 2015-11-05 2023-10-18 ダニスコ・ユーエス・インク パエニバチルス(Paenibacillus)属種及びバチルス(Bacillus)属種のマンナナーゼ
US20190153417A1 (en) 2015-11-05 2019-05-23 Danisco Us Inc Paenibacillus sp. mannanases
EP3374401B1 (en) 2015-11-13 2022-04-06 Nutrition & Biosciences USA 4, Inc. Glucan fiber compositions for use in laundry care and fabric care
JP7045313B2 (ja) 2015-11-13 2022-03-31 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
US10876074B2 (en) 2015-11-13 2020-12-29 Dupont Industrial Biosciences Usa, Llc Glucan fiber compositions for use in laundry care and fabric care
WO2017089093A1 (en) 2015-11-25 2017-06-01 Unilever N.V. A liquid detergent composition
DK3387124T3 (da) 2015-12-09 2021-08-23 William Cuevas Kombinatoriske alfa-amylasevarianter
EP3390625B1 (en) 2015-12-18 2023-09-06 Danisco US Inc. Polypeptides with endoglucanase activity and uses thereof
DE102016205670A1 (de) * 2016-04-06 2017-10-12 Henkel Ag & Co. Kgaa Neue Protease mit verbesserter Waschleistung
BR112018072530A2 (pt) 2016-05-03 2019-03-26 Danisco Us Inc variantes de protease e usos das mesmas
EP3464599A1 (en) 2016-05-31 2019-04-10 Danisco US Inc. Protease variants and uses thereof
WO2017219011A1 (en) 2016-06-17 2017-12-21 Danisco Us Inc Protease variants and uses thereof
US20190264138A1 (en) 2016-11-07 2019-08-29 Danisco Us Inc. Laundry detergent composition
US10550443B2 (en) 2016-12-02 2020-02-04 The Procter & Gamble Company Cleaning compositions including enzymes
WO2018102479A1 (en) 2016-12-02 2018-06-07 The Procter & Gamble Company Cleaning compositions including enzymes
WO2018102478A1 (en) 2016-12-02 2018-06-07 The Procter & Gamble Company Cleaning compositions including enzymes
WO2018118950A1 (en) 2016-12-21 2018-06-28 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
EP3559227B1 (en) 2016-12-21 2025-02-19 Danisco US Inc. Protease variants and uses thereof
EP3583210B1 (en) 2017-03-15 2021-07-07 Danisco US Inc. Trypsin-like serine proteases and uses thereof
US20200040283A1 (en) 2017-03-31 2020-02-06 Danisco Us Inc Delayed release enzyme formulations for bleach-containing detergents
WO2019006077A1 (en) 2017-06-30 2019-01-03 Danisco Us Inc PARTICLES CONTAINING LOW AGGLOMERATION ENZYME
WO2019059804A1 (ru) * 2017-09-25 2019-03-28 Георгий Георгиевич ЧУМБУРИДЗЕ Термостабильная композиция, обладающая антивирусной и антибактериальной активностью и ее использование
WO2019108599A1 (en) 2017-11-29 2019-06-06 Danisco Us Inc Subtilisin variants having improved stability
WO2019125683A1 (en) 2017-12-21 2019-06-27 Danisco Us Inc Enzyme-containing, hot-melt granules comprising a thermotolerant desiccant
WO2019156670A1 (en) 2018-02-08 2019-08-15 Danisco Us Inc. Thermally-resistant wax matrix particles for enzyme encapsulation
US12415996B2 (en) 2018-06-19 2025-09-16 Danisco Us Inc. Subtilisin variants
EP3799601A1 (en) 2018-06-19 2021-04-07 Danisco US Inc. Subtilisin variants
US20210189295A1 (en) 2018-08-30 2021-06-24 Danisco Us Inc Enzyme-containing granules
EP3856882A1 (en) 2018-09-27 2021-08-04 Danisco US Inc. Compositions for medical instrument cleaning
CN111019925B (zh) * 2018-10-10 2022-08-23 上饶市康可得生物科技有限公司 筛选蛋白酶变体的方法以及获得的蛋白酶变体
JP7386552B2 (ja) 2018-10-10 2023-11-27 上饒市康可得生物科技有限公司 プロテアーゼバリアントのスクリーニング方法および得られたプロテアーゼバリアント
EP3887515A1 (en) 2018-11-28 2021-10-06 Danisco US Inc. Subtilisin variants having improved stability
CN109481336B (zh) * 2018-12-19 2021-10-26 广州立白企业集团有限公司 口腔护理组合物及其应用
US20220220419A1 (en) 2019-05-24 2022-07-14 Danisco Us Inc Subtilisin variants and methods of use
US20220306968A1 (en) 2019-06-06 2022-09-29 Danisco Us Inc Methods and compositions for cleaning
IT201900023433A1 (it) 2019-12-10 2021-06-10 Lonati Spa Dispositivo prelevatore per operare il prelievo di un manufatto tubolare a maglia da una macchina circolare per maglieria, calzetteria o simile
US20240034960A1 (en) 2020-08-27 2024-02-01 Danisco Us Inc Enzymes and enzyme compositions for cleaning
CN116997642A (zh) 2021-01-29 2023-11-03 丹尼斯科美国公司 清洁组合物及其相关的方法
US12497644B2 (en) * 2021-02-12 2025-12-16 Fresenius Kabi Ipsum S.R.L. Subtilisin variants and their use
CN112877304B (zh) * 2021-03-15 2022-07-26 合肥师范学院 一种细菌漆酶突变体LacAt及其表达菌株的构建和应用
CN117616120A (zh) 2021-06-30 2024-02-27 丹尼斯科美国公司 变体脂肪酶及其用途
CN117916354A (zh) 2021-09-03 2024-04-19 丹尼斯科美国公司 用于清洁的衣物洗涤组合物
US20240384206A1 (en) 2021-09-13 2024-11-21 Danisco Us Inc. Bioactive-containing granules
WO2023114936A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023114939A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023114932A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
WO2023168234A1 (en) 2022-03-01 2023-09-07 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
CN114733656B (zh) * 2022-04-25 2024-01-23 江苏泓润生物质能科技有限公司 一种用于预处理后的餐厨垃圾同步分相除渣及除杂系统
EP4525615A2 (en) 2022-05-14 2025-03-26 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
EP4544016A1 (en) 2022-06-21 2025-04-30 Danisco US Inc. Methods and compositions for cleaning comprising a polypeptide having thermolysin activity
CA3265943A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. DETERGENT COMPOSITIONS AND ASSOCIATED PROCESSES
CN119816592A (zh) 2022-09-02 2025-04-11 丹尼斯科美国公司 甘露聚糖酶变体和使用方法
JP2025529133A (ja) 2022-09-02 2025-09-04 ダニスコ・ユーエス・インク サブチリシン変異体及びそれに関連する方法
WO2024102698A1 (en) 2022-11-09 2024-05-16 Danisco Us Inc. Subtilisin variants and methods of use
US20240263162A1 (en) * 2023-02-01 2024-08-08 The Procter & Gamble Company Detergent compositions containing enzymes
CN120569471A (zh) * 2023-02-01 2025-08-29 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN120677237A (zh) 2023-02-01 2025-09-19 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN120712348A (zh) 2023-03-06 2025-09-26 丹尼斯科美国公司 枯草杆菌蛋白酶变体和使用方法
CN120813242A (zh) 2023-03-16 2025-10-17 营养与生物科学美国第四公司 用于清洁和臭味控制的短芽孢杆菌发酵物提取物及其用途
WO2025072144A1 (en) * 2023-09-27 2025-04-03 Osprey Biopharmaceuticals, Inc. Polypeptides having human igg cleavage activity
WO2025071996A1 (en) 2023-09-28 2025-04-03 Danisco Us Inc. Variant cutinase enzymes with improved solubility and uses thereof
WO2025085351A1 (en) 2023-10-20 2025-04-24 Danisco Us Inc. Subtilisin variants and methods of use
CN117417922B (zh) * 2023-12-13 2024-03-15 北京科为博生物科技有限公司 一种耐高温碱性蛋白酶及其基因和应用
CN120197407B (zh) * 2025-05-27 2025-08-12 南京华洲药业有限公司 一种除草剂悬浮剂分散稳定性预估优化方法及系统

Family Cites Families (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (enExample) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
GR76237B (enExample) 1981-08-08 1984-08-04 Procter & Gamble
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5801038A (en) * 1984-05-29 1998-09-01 Genencor International Inc. Modified subtilisins having amino acid alterations
US5411873A (en) * 1984-05-29 1995-05-02 Genencor, Inc. Process for producing heterologous polypeptides
US5972682A (en) 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DK154572C (da) 1985-08-07 1989-04-24 Novo Industri As Enzymatisk detergentadditiv, detergent og fremgangsmaade til vask af tekstiler
US4933287A (en) 1985-08-09 1990-06-12 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
ES2068181T3 (es) * 1986-04-30 1995-04-16 Genencor Int Mutantes de la carbonil hidrolasa no humana, secuencias de adn y vectores que codifican las mismas y huespedes transformados con dichos vectores.
US5322770A (en) 1989-12-22 1994-06-21 Hoffman-Laroche Inc. Reverse transcription with thermostable DNA polymerases - high temperature reverse transcription
ATE110768T1 (de) 1986-08-29 1994-09-15 Novo Nordisk As Enzymhaltiger reinigungsmittelzusatz.
US4914031A (en) * 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
WO1988009367A1 (en) 1987-05-29 1988-12-01 Genencor, Inc. Cutinase cleaning composition
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
DE68924654T2 (de) 1988-01-07 1996-04-04 Novonordisk As Spezifische Protease.
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
US4977252A (en) 1988-03-11 1990-12-11 National Starch And Chemical Investment Holding Corporation Modified starch emulsifier characterized by shelf stability
WO1990009446A1 (en) 1989-02-17 1990-08-23 Plant Genetic Systems N.V. Cutinase
BR9006827A (pt) * 1989-06-26 1991-08-06 Unilever Nv Composicoes detergentes enzimaticas
DK316989D0 (da) * 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
US5665587A (en) * 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
DE4111321A1 (de) 1990-04-14 1991-10-17 Kali Chemie Ag Alkalische bacillus-lipasen, hierfuer codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren
US5354559A (en) 1990-05-29 1994-10-11 Grain Processing Corporation Encapsulation with starch hydrolyzate acid esters
US5766898A (en) * 1990-12-05 1998-06-16 Novo Nordisk A/S Proteins with changed epitopes and methods for the production thereof
ATE219136T1 (de) 1991-01-16 2002-06-15 Procter & Gamble Kompakte waschmittelzusammensetzungen mit hochaktiven cellulasen
US5340735A (en) 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
AU682314B2 (en) * 1992-07-17 1997-10-02 Genencor International, Inc. High alkaline serine proteases
DE4231726A1 (de) * 1992-09-23 1994-03-24 Cognis Bio Umwelt Mutierte subtilisinartige Serinproteasen
DE69331907T2 (de) * 1992-09-24 2002-09-05 Genencor International, Inc. Neue alkalische proteasen enthaltende reinigungsmittelzusammensetzungen
ATE237681T1 (de) 1992-12-01 2003-05-15 Novozymes As Beschleunigung von enzymreaktionen
WO1994016048A1 (en) 1993-01-18 1994-07-21 The Procter & Gamble Company Machine dishwashing detergent compositions
DK77393D0 (da) 1993-06-29 1993-06-29 Novo Nordisk As Aktivering af enzymer
US5698504A (en) 1993-07-01 1997-12-16 The Procter & Gamble Company Machine dishwashing composition containing oxygen bleach and paraffin oil and benzotriazole compound silver tarnishing inhibitors
US5486303A (en) 1993-08-27 1996-01-23 The Procter & Gamble Company Process for making high density detergent agglomerates using an anhydrous powder additive
CN1057123C (zh) 1993-09-15 2000-10-04 普罗格特-甘布尔公司 降低了吸附能力以及增加了水解能力的枯草杆菌蛋白酶bpn变体
US6436690B1 (en) * 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
MA23346A1 (fr) * 1993-10-14 1995-04-01 Genencor Int Variantes de la subtilisine
CZ105296A3 (en) * 1993-10-14 1996-09-11 Procter & Gamble Bleaching agent containing protease enzymes, cleansing agents, agent for cleaning fabrics and fabric cleaning method
ES2287931T3 (es) * 1993-10-14 2007-12-16 THE PROCTER & GAMBLE COMPANY Composiciones limpiadoras que contienen proteasa.
DE4342680A1 (de) 1993-12-15 1995-06-22 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US5861271A (en) 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
EP0701605B2 (en) 1994-02-24 2017-02-22 Basf Se Improved enzymes and detergents containing them
ES2364776T3 (es) 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US5691295A (en) 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
US5686014A (en) 1994-04-07 1997-11-11 The Procter & Gamble Company Bleach compositions comprising manganese-containing bleach catalysts
AU704022B2 (en) 1994-06-17 1999-04-15 Genencor International, Inc. Cleaning compositions containing plant cell wall degrading enzymes and their use in cleaning methods
GB2294268A (en) 1994-07-07 1996-04-24 Procter & Gamble Bleaching composition for dishwasher use
GB9416841D0 (en) * 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
US5879584A (en) 1994-09-10 1999-03-09 The Procter & Gamble Company Process for manufacturing aqueous compositions comprising peracids
US5516448A (en) 1994-09-20 1996-05-14 The Procter & Gamble Company Process for making a high density detergent composition which includes selected recycle streams for improved agglomerate
US5691297A (en) 1994-09-20 1997-11-25 The Procter & Gamble Company Process for making a high density detergent composition by controlling agglomeration within a dispersion index
US5489392A (en) 1994-09-20 1996-02-06 The Procter & Gamble Company Process for making a high density detergent composition in a single mixer/densifier with selected recycle streams for improved agglomerate properties
WO1996017921A1 (en) 1994-12-09 1996-06-13 The Procter & Gamble Company Automatic dishwashing composition containing particles of diacyl peroxides
US5534179A (en) 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
US5574005A (en) 1995-03-07 1996-11-12 The Procter & Gamble Company Process for producing detergent agglomerates from high active surfactant pastes having non-linear viscoelastic properties
US5569645A (en) 1995-04-24 1996-10-29 The Procter & Gamble Company Low dosage detergent composition containing optimum proportions of agglomerates and spray dried granules for improved flow properties
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
ATE203051T1 (de) 1995-06-16 2001-07-15 Procter & Gamble Maschinengeschirrspülmittel, die kobaltkatalysatoren enthalten
US5565422A (en) 1995-06-23 1996-10-15 The Procter & Gamble Company Process for preparing a free-flowing particulate detergent composition having improved solubility
DE19530816A1 (de) 1995-08-23 1997-02-27 Cognis Bio Umwelt Verwendung von mutierter Subtilisin-Protease in kosmetischen Produkten
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
HUP9802268A3 (en) 1995-09-18 2000-03-28 Procter And Gamble Company Cin Delivery systems for detergent comprising glass-stage granules
US5879564A (en) 1995-11-14 1999-03-09 Cytec Technology Corp. High performance polymer flocculating agents
MA24136A1 (fr) 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface .
ATE409743T1 (de) * 1996-11-04 2008-10-15 Novozymes As Subtilase varianten und verbindungen
BR9712473B1 (pt) * 1996-11-04 2009-08-11 variantes de subtilase e composições.
DE69830574T2 (de) 1997-03-07 2006-05-04 The Procter & Gamble Company, Cincinnati Verbesserte verfahren zur herstellung von vernetzt verbrückten macropolycyclen
US6306812B1 (en) 1997-03-07 2001-10-23 Procter & Gamble Company, The Bleach compositions containing metal bleach catalyst, and bleach activators and/or organic percarboxylic acids
AU9061898A (en) * 1997-08-29 1999-03-22 Novo Nordisk A/S Protease variants and compositions
RU2252958C2 (ru) * 1997-10-23 2005-05-27 Джененкор Интернэшнл, Инк. Вариант субтилизина (варианты), кодирующая его днк, экспрессирующий вектор, очищающая композиция, корм для животных, композиция для обработки ткани
AR015977A1 (es) * 1997-10-23 2001-05-30 Genencor Int Variantes de proteasa multiplemente substituida con carga neta alterada para su empleo en detergentes
US5935826A (en) 1997-10-31 1999-08-10 National Starch And Chemical Investment Holding Corporation Glucoamylase converted starch derivatives and their use as emulsifying and encapsulating agents
KR100762164B1 (ko) 1997-11-21 2007-10-01 노보자임스 에이/에스 프로테아제 변이체 및 조성물
US6773907B2 (en) * 1997-11-21 2004-08-10 Peter Kamp Hansen Subtilase enzymes
WO2000071686A1 (en) * 1999-05-20 2000-11-30 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 97 and 98
WO1999034011A2 (en) 1997-12-24 1999-07-08 Genencor International, Inc. Method of assaying for a preferred enzyme and/or detergent
US6936249B1 (en) * 1998-04-15 2005-08-30 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
CN101024826B (zh) 1998-06-10 2014-09-03 诺沃奇梅兹有限公司 新的甘露聚糖酶
US6461849B1 (en) * 1998-10-13 2002-10-08 Novozymes, A/S Modified polypeptide
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
CA2348893A1 (en) 1998-11-30 2000-06-08 The Procter & Gamble Company Process for preparing cross-bridged tetraaza macrocycles
ES2281976T3 (es) * 1998-12-18 2007-10-01 Novozymes A/S Enzimas subtilasas de los subgrupos i-s1 y i-s2 que tienen un residuo aminoacido adicional en la region del bucle del sitio activo.
DE69933694T2 (de) * 1998-12-18 2007-08-23 Novozymes A/S SUBTILASE ENZYME DER I-S1 und IS2 UNTERGRUPPEN, MIT EINEM ZUSÄTZLICHEN AMINOSAÜREREST IN EINER AKTIVEN SCHLEIFENREGION
EP1141258B1 (en) * 1998-12-18 2007-08-22 Novozymes A/S Subtilase enzymes of the i-s1 and i-s2 sub-groups having an additional amino acid residue in an active site loop region
JP2003505070A (ja) * 1999-07-22 2003-02-12 ザ、プロクター、エンド、ギャンブル、カンパニー 定められたエピトープ領域においてアミノ酸置換を有するサブチリシンプロテアーゼ変異体
US6525012B2 (en) * 2000-02-23 2003-02-25 The Procter & Gamble Company Liquid laundry detergent compositions having enhanced clay removal benefits
AU2001249811B2 (en) * 2000-04-03 2006-06-08 Maxygen, Inc. Subtilisin variants
EP1280817A2 (en) * 2000-04-28 2003-02-05 Novozymes A/S Production and use of protein variants having modified immunogenecity
DK1309677T4 (da) 2000-08-11 2012-06-25 Genencor Int Bacillustransformation, transformanter og mutantbiblioteker
US6541235B1 (en) * 2000-09-29 2003-04-01 University Of Maryland Biotechnology Institute Calcium free subtilisin mutants
US6440991B1 (en) 2000-10-02 2002-08-27 Wyeth Ethers of 7-desmethlrapamycin
US6582914B1 (en) 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
PL210859B1 (pl) * 2001-03-23 2012-03-30 Genencor Int Odmiana subtylizyny zawierająca zmieniony epitop limfocytów T, kwas nukleinowy kodujący tę odmianę subtylizyny, wektor ekspresyjny i komórka gospodarza zawierająca kwas nukleinowy oraz kompozycje zawierające tę odmianę subtylizyny
JP2005515180A (ja) * 2001-11-13 2005-05-26 ザ プロクター アンド ギャンブル カンパニー 阻害物質で安定化させた酵素を含有する局所適用組成物
US7332320B2 (en) * 2001-12-31 2008-02-19 Genencor International, Inc. Protease producing an altered immunogenic response and methods of making and using the same
CA2471972A1 (en) * 2001-12-31 2003-07-17 Genencor International, Inc. Proteases producing an altered immunological response and methods of making and using the same
ES2336092T3 (es) * 2002-01-16 2010-04-08 Genencor International, Inc. Variantes de proteasas con multiples sustituciones.
WO2003072746A2 (en) * 2002-02-26 2003-09-04 Genencor International, Inc. Subtilisin carlsberg proteins with reduced immunogenicity
TWI319007B (en) * 2002-11-06 2010-01-01 Novozymes As Subtilase variants
US7888093B2 (en) * 2002-11-06 2011-02-15 Novozymes A/S Subtilase variants
US20040214737A1 (en) * 2003-04-25 2004-10-28 John Billman Foamy composition for pretreatment of stains on fabrics
EP1627885B8 (en) * 2003-04-30 2015-02-18 Innovative Medicine and Any Peptide Pharmaceuticals Corp Polypeptide capable of assisting digestive organ absorption
WO2005052161A2 (en) 2003-11-19 2005-06-09 Genencor International, Inc. Serine proteases, nucleic acids encoding serine enzymes and vectors and host cells incorporating same
CN1981035B (zh) 2003-12-03 2011-06-08 金克克国际有限公司 过水解酶
JP2007532117A (ja) 2004-04-08 2007-11-15 ジェネンコー・インターナショナル・インク αアミラーゼ変異体
DE102004027091A1 (de) * 2004-06-02 2005-12-29 Henkel Kgaa Leistungsverbesserte Alkalische Protease-Varianten und Wasch- und Reinigungsmittel, enthaltend diese leistungsverbesserten Alkalische Protease-Varianten
MX2007016045A (es) * 2005-07-08 2008-03-10 Novozymes As Variantes de subtilasa.
DK1934340T3 (da) 2005-10-12 2014-06-16 Danisco Us Inc Anvendelse og fremstilling af en opbevaringsstabil neutral metalloprotease
JP2009534022A (ja) * 2006-04-20 2009-09-24 ノボザイムス アクティーゼルスカブ 卵のシミに対する洗浄能力が向上したサビナーゼ変異体
CA2652792A1 (en) * 2006-06-05 2007-12-21 The Procter & Gamble Company Enzyme stabilization
CN101511998A (zh) * 2006-07-18 2009-08-19 丹尼斯科美国公司 在宽温度范围内具有活性的蛋白酶变体
EP2297315A2 (en) * 2008-06-06 2011-03-23 Danisco US Inc. Compositions and methods comprising variant microbial proteases
EP2362897A2 (en) * 2008-11-11 2011-09-07 Danisco US Inc. Compositions and methods comprising serine protease variants
CN102652175B (zh) * 2009-12-09 2016-02-10 宝洁公司 织物和家居护理产品
CN105368809A (zh) * 2009-12-09 2016-03-02 丹尼斯科美国公司 包含蛋白酶变体的组合物和方法
EP2551335A1 (en) * 2011-07-25 2013-01-30 The Procter & Gamble Company Enzyme stabilized liquid detergent composition
US20130123162A1 (en) * 2011-11-10 2013-05-16 The Procter & Gamble Company Consumer products

Also Published As

Publication number Publication date
BRPI0913623A8 (pt) 2017-10-03
EP2947147A2 (en) 2015-11-25
EP2297315A2 (en) 2011-03-23
BRPI0915073A2 (pt) 2019-09-24
AU2009256295A1 (en) 2009-12-10
US20110251073A1 (en) 2011-10-13
CA2726450A1 (en) 2009-12-10
CN104130993B (zh) 2018-10-23
MX383345B (es) 2025-03-13
WO2009149145A3 (en) 2010-01-28
KR20110015006A (ko) 2011-02-14
US10563189B2 (en) 2020-02-18
KR20110015004A (ko) 2011-02-14
CN103382420B (zh) 2015-10-28
US20180223269A1 (en) 2018-08-09
US12410420B2 (en) 2025-09-09
MX2010013121A (es) 2011-01-21
DK2297314T3 (en) 2015-07-13
CA2726451A1 (en) 2009-12-10
EP3095859A1 (en) 2016-11-23
DK2578680T3 (en) 2016-08-15
JP2011524166A (ja) 2011-09-01
JP2018050618A (ja) 2018-04-05
JP2013240327A (ja) 2013-12-05
JP2011522539A (ja) 2011-08-04
BRPI0915681A2 (pt) 2015-08-04
US20200190497A1 (en) 2020-06-18
EP2578679A1 (en) 2013-04-10
JP6426391B2 (ja) 2018-11-21
US20220025350A1 (en) 2022-01-27
CN103382421B (zh) 2016-01-20
CN102112607B (zh) 2014-08-20
MX360255B (es) 2018-10-26
US20240309352A1 (en) 2024-09-19
AU2009256294A1 (en) 2009-12-10
WO2009149144A3 (en) 2010-04-15
JP5647976B2 (ja) 2015-01-07
EP2647701A3 (en) 2013-12-25
RU2010154103A (ru) 2012-07-20
US20110256610A1 (en) 2011-10-20
WO2009149144A2 (en) 2009-12-10
CN104694519B (zh) 2023-10-27
EP2647701A2 (en) 2013-10-09
US20110256609A1 (en) 2011-10-20
BRPI0913623A2 (pt) 2015-08-04
EP2647702A3 (en) 2013-12-25
EP2578680A1 (en) 2013-04-10
CN102057043B (zh) 2015-03-04
KR20110020245A (ko) 2011-03-02
WO2009149145A2 (en) 2009-12-10
RU2010153864A (ru) 2012-07-20
JP2015012864A (ja) 2015-01-22
EP3173479A1 (en) 2017-05-31
CN103382421A (zh) 2013-11-06
RU2541786C2 (ru) 2015-02-20
EP2578680B1 (en) 2016-04-27
JP2011522537A (ja) 2011-08-04
CN102057043A (zh) 2011-05-11
EP2297316A2 (en) 2011-03-23
CA2726370A1 (en) 2009-12-10
WO2009149200A3 (en) 2010-07-29
ZA201008169B (en) 2012-02-29
CN104130993A (zh) 2014-11-05
EP2947147A3 (en) 2015-12-23
JP2013223499A (ja) 2013-10-31
WO2009149200A2 (en) 2009-12-10
MX2010013100A (es) 2010-12-21
CN104694519A (zh) 2015-06-10
MX350188B (es) 2017-08-30
EP2297314B1 (en) 2015-04-15
JP6067221B2 (ja) 2017-01-25
US20180051269A1 (en) 2018-02-22
US20150247140A1 (en) 2015-09-03
US12448616B2 (en) 2025-10-21
CN103382420A (zh) 2013-11-06
US20150056682A1 (en) 2015-02-26
RU2010153866A (ru) 2012-07-20
CN102046783A (zh) 2011-05-04
US20150064767A1 (en) 2015-03-05
MX2010013101A (es) 2010-12-21
JP2015211671A (ja) 2015-11-26
EP2297314A2 (en) 2011-03-23
CN102112607A (zh) 2011-06-29
EP2647702A2 (en) 2013-10-09
US20150159147A1 (en) 2015-06-11

Similar Documents

Publication Publication Date Title
US12448616B2 (en) Compositions and methods comprising variant microbial proteases
US10093887B2 (en) Compositions and methods comprising serine protease variants
RU2575073C2 (ru) Композиции и способы, включающие в себя применение вариантных микробных протеаз
AU2014201929A1 (en) Compositions and methods comprising variant microbial proteases
AU2014201928A1 (en) Compositions and methods comprising variant microbial proteases

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted