AU2009205060C1 - Combination therapy comprising SGLT inhibitors and DPP4 inhibitors - Google Patents

Combination therapy comprising SGLT inhibitors and DPP4 inhibitors Download PDF

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Publication number
AU2009205060C1
AU2009205060C1 AU2009205060A AU2009205060A AU2009205060C1 AU 2009205060 C1 AU2009205060 C1 AU 2009205060C1 AU 2009205060 A AU2009205060 A AU 2009205060A AU 2009205060 A AU2009205060 A AU 2009205060A AU 2009205060 C1 AU2009205060 C1 AU 2009205060C1
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AU
Australia
Prior art keywords
alkyl
group
formula
inhibitor
compound
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Ceased
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AU2009205060A
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AU2009205060A1 (en
AU2009205060B2 (en
Inventor
Kenji Arakawa
Yasuaki Matsushita
Kiichiro Ueta
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Mitsubishi Tanabe Pharma Corp
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Mitsubishi Tanabe Pharma Corp
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Publication of AU2009205060A1 publication Critical patent/AU2009205060A1/en
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Publication of AU2009205060B2 publication Critical patent/AU2009205060B2/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
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    • C—CHEMISTRY; METALLURGY
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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2009205060A 2008-01-17 2009-01-16 Combination therapy comprising SGLT inhibitors and DPP4 inhibitors Ceased AU2009205060C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2177708P 2008-01-17 2008-01-17
US61/021,777 2008-01-17
PCT/JP2009/051023 WO2009091082A1 (en) 2008-01-17 2009-01-16 Combination therapy comprising sglt inhibitors and dpp4 inhibitors

Publications (3)

Publication Number Publication Date
AU2009205060A1 AU2009205060A1 (en) 2009-07-23
AU2009205060B2 AU2009205060B2 (en) 2013-06-27
AU2009205060C1 true AU2009205060C1 (en) 2013-12-19

Family

ID=40433628

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2009205060A Ceased AU2009205060C1 (en) 2008-01-17 2009-01-16 Combination therapy comprising SGLT inhibitors and DPP4 inhibitors

Country Status (14)

Country Link
US (2) US8853385B2 (enExample)
EP (1) EP2252289B1 (enExample)
JP (3) JP5204849B2 (enExample)
KR (1) KR101257554B1 (enExample)
CN (2) CN101932321B (enExample)
AR (1) AR070193A1 (enExample)
AU (1) AU2009205060C1 (enExample)
BR (1) BRPI0906735A2 (enExample)
CA (1) CA2712614C (enExample)
CL (1) CL2008003653A1 (enExample)
ES (1) ES2763239T3 (enExample)
MX (1) MX2010007818A (enExample)
TW (1) TWI437996B (enExample)
WO (1) WO2009091082A1 (enExample)

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