JP5204849B2 - Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法 - Google Patents

Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法 Download PDF

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JP5204849B2
JP5204849B2 JP2010528230A JP2010528230A JP5204849B2 JP 5204849 B2 JP5204849 B2 JP 5204849B2 JP 2010528230 A JP2010528230 A JP 2010528230A JP 2010528230 A JP2010528230 A JP 2010528230A JP 5204849 B2 JP5204849 B2 JP 5204849B2
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alkyl
acceptable salt
pharmaceutically acceptable
substituted
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JP2011509922A5 (enExample
JP2011509922A (ja
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喜一郎 植田
健司 荒川
泰明 松下
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Mitsubishi Tanabe Pharma Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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  • Animal Behavior & Ethology (AREA)
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  • Organic Chemistry (AREA)
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  • Epidemiology (AREA)
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  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010528230A 2008-01-17 2009-01-16 Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法 Active JP5204849B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2177708P 2008-01-17 2008-01-17
US61/021,777 2008-01-17
PCT/JP2009/051023 WO2009091082A1 (en) 2008-01-17 2009-01-16 Combination therapy comprising sglt inhibitors and dpp4 inhibitors

Related Child Applications (1)

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JP2012284625A Division JP5646588B2 (ja) 2008-01-17 2012-12-27 Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法

Publications (3)

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JP2011509922A JP2011509922A (ja) 2011-03-31
JP2011509922A5 JP2011509922A5 (enExample) 2012-03-01
JP5204849B2 true JP5204849B2 (ja) 2013-06-05

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JP2010528230A Active JP5204849B2 (ja) 2008-01-17 2009-01-16 Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法
JP2012284625A Active JP5646588B2 (ja) 2008-01-17 2012-12-27 Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法
JP2014225301A Active JP5908563B2 (ja) 2008-01-17 2014-11-05 Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法

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JP2012284625A Active JP5646588B2 (ja) 2008-01-17 2012-12-27 Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法
JP2014225301A Active JP5908563B2 (ja) 2008-01-17 2014-11-05 Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法

Country Status (14)

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US (2) US8853385B2 (enExample)
EP (1) EP2252289B1 (enExample)
JP (3) JP5204849B2 (enExample)
KR (1) KR101257554B1 (enExample)
CN (2) CN101932321B (enExample)
AR (1) AR070193A1 (enExample)
AU (1) AU2009205060C1 (enExample)
BR (1) BRPI0906735A2 (enExample)
CA (1) CA2712614C (enExample)
CL (1) CL2008003653A1 (enExample)
ES (1) ES2763239T3 (enExample)
MX (1) MX2010007818A (enExample)
TW (1) TWI437996B (enExample)
WO (1) WO2009091082A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013091654A (ja) * 2008-01-17 2013-05-16 Mitsubishi Tanabe Pharma Corp Ｓｇｌｔ阻害剤及びｄｐｐ４阻害剤からなる併用療法

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US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
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BR112012012641A2 (pt) 2009-11-27 2020-08-11 Boehringer Ingelheim International Gmbh TRATAMENTO DE PACIENTES DIABÉTICOS GENOTIPADOS COM INIBIDORES DE DPP-lVTAL COMO LINAGLIPTINA
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