AU2004261353B2 - Novel insulin derivatives - Google Patents

Novel insulin derivatives Download PDF

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Publication number
AU2004261353B2
AU2004261353B2 AU2004261353A AU2004261353A AU2004261353B2 AU 2004261353 B2 AU2004261353 B2 AU 2004261353B2 AU 2004261353 A AU2004261353 A AU 2004261353A AU 2004261353 A AU2004261353 A AU 2004261353A AU 2004261353 B2 AU2004261353 B2 AU 2004261353B2
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AU
Australia
Prior art keywords
insulin
glu
des
asp
human insulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active, expires
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AU2004261353A
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English (en)
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AU2004261353A1 (en
Inventor
Svend Havelund
Thomas Hoeg-Jensen
Ib Jonassen
Peter Madsen
Ulla Ribel-Madsen
Tina Moller Tagmose
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Novo Nordisk AS
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Novo Nordisk AS
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Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of AU2004261353A1 publication Critical patent/AU2004261353A1/en
Application granted granted Critical
Publication of AU2004261353B2 publication Critical patent/AU2004261353B2/en
Priority to AU2010200497A priority Critical patent/AU2010200497B2/en
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2004261353A 2003-08-05 2004-07-22 Novel insulin derivatives Active 2029-07-22 AU2004261353B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2010200497A AU2010200497B2 (en) 2003-08-05 2010-02-10 Novel insulin derivatives

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200301129 2003-08-05
DKPA200301129 2003-08-05
US49545103P 2003-08-14 2003-08-14
US60/495,451 2003-08-14
PCT/DK2004/000511 WO2005012347A2 (en) 2003-08-05 2004-07-22 Novel insulin derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2010200497A Division AU2010200497B2 (en) 2003-08-05 2010-02-10 Novel insulin derivatives

Publications (2)

Publication Number Publication Date
AU2004261353A1 AU2004261353A1 (en) 2005-02-10
AU2004261353B2 true AU2004261353B2 (en) 2009-12-10

Family

ID=34117520

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2004261353A Active 2029-07-22 AU2004261353B2 (en) 2003-08-05 2004-07-22 Novel insulin derivatives
AU2010200497A Active 2029-07-22 AU2010200497B2 (en) 2003-08-05 2010-02-10 Novel insulin derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2010200497A Active 2029-07-22 AU2010200497B2 (en) 2003-08-05 2010-02-10 Novel insulin derivatives

Country Status (18)

Country Link
US (3) US7615532B2 (enExample)
EP (3) EP2107069B1 (enExample)
JP (1) JP4463814B2 (enExample)
KR (1) KR101159559B1 (enExample)
AU (2) AU2004261353B2 (enExample)
BE (2) BE2013C035I2 (enExample)
BR (1) BRPI0413276B8 (enExample)
CA (1) CA2531988C (enExample)
CY (5) CY1113850T1 (enExample)
FR (2) FR13C0035I2 (enExample)
HU (1) HUS1300033I1 (enExample)
IL (1) IL172980A (enExample)
LU (2) LU92213I2 (enExample)
MX (1) MXPA06001283A (enExample)
NO (5) NO340925B1 (enExample)
PL (1) PL2107069T3 (enExample)
RU (1) RU2518460C2 (enExample)
WO (1) WO2005012347A2 (enExample)

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* Cited by examiner, † Cited by third party
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