NO2018002I2 - Insulin degludec i alle dens former som de er beskyttet av basispatentet - Google Patents
Insulin degludec i alle dens former som de er beskyttet av basispatentetInfo
- Publication number
- NO2018002I2 NO2018002I2 NO2018002C NO2018002C NO2018002I2 NO 2018002 I2 NO2018002 I2 NO 2018002I2 NO 2018002 C NO2018002 C NO 2018002C NO 2018002 C NO2018002 C NO 2018002C NO 2018002 I2 NO2018002 I2 NO 2018002I2
- Authority
- NO
- Norway
- Prior art keywords
- protected
- forms
- insulin degludec
- basic patent
- basic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200301129 | 2003-08-05 | ||
US49545103P | 2003-08-14 | 2003-08-14 | |
PCT/DK2004/000511 WO2005012347A2 (en) | 2003-08-05 | 2004-07-22 | Novel insulin derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
NO2018002I1 NO2018002I1 (no) | 2018-01-11 |
NO2018002I2 true NO2018002I2 (no) | 2018-08-20 |
Family
ID=34117520
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20061026A NO340925B1 (no) | 2003-08-05 | 2006-03-02 | Nye insulinderivater |
NO2018003C NO2018003I1 (no) | 2003-08-05 | 2018-01-11 | Combination of insulin degludec and insulin aspart |
NO2018002C NO2018002I2 (no) | 2003-08-05 | 2018-01-11 | Insulin degludec i alle dens former som de er beskyttet av basispatentet |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20061026A NO340925B1 (no) | 2003-08-05 | 2006-03-02 | Nye insulinderivater |
NO2018003C NO2018003I1 (no) | 2003-08-05 | 2018-01-11 | Combination of insulin degludec and insulin aspart |
Country Status (18)
Country | Link |
---|---|
US (3) | US7615532B2 (no) |
EP (3) | EP2107069B1 (no) |
JP (1) | JP4463814B2 (no) |
KR (1) | KR101159559B1 (no) |
AU (2) | AU2004261353B2 (no) |
BE (2) | BE2013C035I2 (no) |
BR (1) | BRPI0413276B8 (no) |
CA (1) | CA2531988C (no) |
CY (3) | CY1113850T1 (no) |
FR (2) | FR13C0035I2 (no) |
HU (1) | HUS1300033I1 (no) |
IL (1) | IL172980A (no) |
LU (2) | LU92213I2 (no) |
MX (1) | MXPA06001283A (no) |
NO (3) | NO340925B1 (no) |
PL (1) | PL2107069T3 (no) |
RU (1) | RU2518460C2 (no) |
WO (1) | WO2005012347A2 (no) |
Families Citing this family (95)
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EP2107069B1 (en) | 2003-08-05 | 2013-01-16 | Novo Nordisk A/S | Novel insulin derivatives |
US20080171695A1 (en) * | 2005-02-02 | 2008-07-17 | Novo Nordisk A/S | Insulin Derivatives |
US8067362B2 (en) | 2005-02-02 | 2011-11-29 | Novo Nordisk As | Insulin derivatives |
ES2371361T3 (es) * | 2005-12-28 | 2011-12-30 | Novo Nordisk A/S | Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones. |
US8722620B2 (en) | 2006-02-27 | 2014-05-13 | Novo Nordisk A/S | Insulin derivatives |
WO2007104736A2 (en) * | 2006-03-13 | 2007-09-20 | Novo Nordisk A/S | Acylated single chain insulin |
US8293965B2 (en) | 2006-04-28 | 2012-10-23 | Kimberly-Clark Worldwide, Inc. | Antimicrobial site dressings |
CN101437849B (zh) * | 2006-05-09 | 2015-09-30 | 诺沃-诺迪斯克有限公司 | 胰岛素衍生物 |
EP2386572B1 (en) * | 2006-05-09 | 2015-07-08 | Novo Nordisk A/S | Insulin derivative |
EP2024390B1 (en) | 2006-05-09 | 2015-08-19 | Novo Nordisk A/S | Insulin derivative |
JP5097900B2 (ja) * | 2006-06-27 | 2012-12-12 | 独立行政法人物質・材料研究機構 | 有機酸又はこれらの誘導体の活性エステル体の製造方法 |
CN101573133B (zh) * | 2006-07-31 | 2014-08-27 | 诺沃-诺迪斯克有限公司 | Peg化延长的胰岛素 |
JP5864834B2 (ja) | 2006-09-22 | 2016-02-17 | ノボ・ノルデイスク・エー/エス | プロテアーゼ耐性のインスリンアナログ |
EP2152245B1 (en) | 2007-04-30 | 2015-12-02 | Novo Nordisk A/S | Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein |
EP2514406A1 (en) | 2007-06-01 | 2012-10-24 | Novo Nordisk A/S | Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier |
AU2008257505B2 (en) * | 2007-06-01 | 2013-05-16 | Novo Nordisk A/S | Stable non-aqueous pharmaceutical compositions |
JP5552046B2 (ja) * | 2007-06-13 | 2014-07-16 | ノボ・ノルデイスク・エー/エス | インスリン誘導体を含有する薬学的製剤 |
JP5721432B2 (ja) * | 2007-08-15 | 2015-05-20 | ノボ・ノルデイスク・エー/エス | アミノ酸含有アルキレングリコール反復単位を含むアシル部を有するインスリン |
RU2514430C2 (ru) * | 2007-08-15 | 2014-04-27 | Ново Нордиск А/С | Аналоги инсулина с ацильной и алкиленгликолевой группировкой |
CN101157725B (zh) * | 2007-10-24 | 2012-07-25 | 中国药科大学 | 人胰岛素类似物的制备方法及用途 |
US8710000B2 (en) | 2007-11-08 | 2014-04-29 | Novo Nordisk A/S | Insulin derivative |
US8937042B2 (en) | 2007-11-16 | 2015-01-20 | Novo Nordisk A/S | Pharmaceutical compositions comprising GLP-1 peptides or extendin-4 and a basal insulin peptide |
EP2254905B1 (en) | 2008-03-14 | 2016-12-14 | Novo Nordisk A/S | Protease-stabilized insulin analogues |
EP2910570B1 (en) | 2008-03-18 | 2016-10-12 | Novo Nordisk A/S | Protease stabilized, acylated insulin analogues |
ES2561208T3 (es) | 2008-09-12 | 2016-02-25 | Novo Nordisk A/S | Método de acilación de un péptido o una proteína |
US9603904B2 (en) * | 2008-10-30 | 2017-03-28 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections with less than daily injection frequency |
RU2525393C2 (ru) | 2009-01-23 | 2014-08-10 | Ново Нордиск А/С | Производные fgf21 со связующим альбумина а-в-с-d-e- и их применение |
US8835379B2 (en) | 2009-10-30 | 2014-09-16 | Novo Nordisk A/S | Derivatives of CGRP |
CN102753150A (zh) | 2010-01-12 | 2012-10-24 | 诺沃—诺迪斯克有限公司 | 用于口服给予胰岛素肽的药物组合物 |
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EP2536434B1 (en) | 2010-02-16 | 2016-04-20 | Novo Nordisk A/S | Purification method |
KR20130092972A (ko) | 2010-05-10 | 2013-08-21 | 노보 노르디스크 에이/에스 | 인슐린-아연 복합체의 제조 방법 |
WO2011146973A1 (en) | 2010-05-25 | 2011-12-01 | Monash University | Insulin analogues |
JP5931857B2 (ja) | 2010-06-23 | 2016-06-08 | ノヴォ ノルディスク アー/エス | 追加のジスルフィド結合を含有するインスリン誘導体 |
EP2585483A1 (en) | 2010-06-23 | 2013-05-01 | Novo Nordisk A/S | Human insulin containing additional disulfide bonds |
CN102947331B (zh) | 2010-06-23 | 2016-08-03 | 诺沃—诺迪斯克有限公司 | 包含额外的二硫键的胰岛素类似物 |
JP2013540771A (ja) | 2010-10-15 | 2013-11-07 | ノヴォ ノルディスク アー/エス | 新規n末端修飾インスリン誘導体 |
JP6049625B2 (ja) * | 2010-10-27 | 2016-12-21 | ノヴォ ノルディスク アー/エス | 様々な注射間隔を用いて施されるインスリン注射を使用する、真性糖尿病の治療 |
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JP2014510516A (ja) | 2011-02-15 | 2014-05-01 | ノヴォ ノルディスク アー/エス | 長時間作用性il−1受容体アンタゴニスト |
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JP6030630B2 (ja) | 2011-04-14 | 2016-11-24 | ノヴォ ノルディスク アー/エス | 経口ペプチド送達のための脂肪酸アシル化アミノ酸 |
JP6058646B2 (ja) | 2011-06-15 | 2017-01-11 | ノヴォ ノルディスク アー/エス | 多置換インスリン |
JP6352806B2 (ja) | 2011-09-23 | 2018-07-04 | ノヴォ ノルディスク アー/エス | 新規のグルカゴン類似体 |
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ES2594303T3 (es) | 2012-04-11 | 2016-12-19 | Novo Nordisk A/S | Formulaciones de insulina |
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