IT1240314B - Formulazioni acquose stabilizzate di piccoli peptidi. - Google Patents

Formulazioni acquose stabilizzate di piccoli peptidi.

Info

Publication number
IT1240314B
IT1240314B IT19421A IT1942190A IT1240314B IT 1240314 B IT1240314 B IT 1240314B IT 19421 A IT19421 A IT 19421A IT 1942190 A IT1942190 A IT 1942190A IT 1240314 B IT1240314 B IT 1240314B
Authority
IT
Italy
Prior art keywords
small peptides
aqueous formulations
stabilized aqueous
stabilized
formulations
Prior art date
Application number
IT19421A
Other languages
English (en)
Other versions
IT9019421A0 (it
IT9019421A1 (it
Inventor
Goldstein Gideon
Audhya Tapan
Original Assignee
Immunobiology Research Institutes, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunobiology Research Institutes, Inc. filed Critical Immunobiology Research Institutes, Inc.
Publication of IT9019421A0 publication Critical patent/IT9019421A0/it
Publication of IT9019421A1 publication Critical patent/IT9019421A1/it
Application granted granted Critical
Publication of IT1240314B publication Critical patent/IT1240314B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
IT19421A 1989-09-28 1990-02-20 Formulazioni acquose stabilizzate di piccoli peptidi. IT1240314B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41384189A 1989-09-28 1989-09-28

Publications (3)

Publication Number Publication Date
IT9019421A0 IT9019421A0 (it) 1990-02-20
IT9019421A1 IT9019421A1 (it) 1991-03-29
IT1240314B true IT1240314B (it) 1993-12-07

Family

ID=23638883

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19421A IT1240314B (it) 1989-09-28 1990-02-20 Formulazioni acquose stabilizzate di piccoli peptidi.

Country Status (14)

Country Link
EP (1) EP0420649A3 (it)
JP (1) JPH04502017A (it)
AU (1) AU6446790A (it)
BR (1) BR9006934A (it)
CA (1) CA2026149A1 (it)
DD (1) DD298053A5 (it)
HU (1) HUT59013A (it)
IE (1) IE903475A1 (it)
IL (1) IL95663A0 (it)
IT (1) IT1240314B (it)
NZ (1) NZ235324A (it)
PT (1) PT95451A (it)
WO (1) WO1991004743A1 (it)
ZA (1) ZA907492B (it)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5036050A (en) * 1989-01-12 1991-07-30 Immunobiology Research Institute, Inc. Compositions containing thymopentin for topical treatment of skin disorders
EP0689843B1 (en) * 1993-12-17 2003-09-10 Mochida Pharmaceutical Co., Ltd. Composition containing soluble thrombomodulins
CA2192725C (en) 1995-12-28 2004-04-20 Kenji Tsujihara Camptothecin derivatives
US8632778B2 (en) 2000-08-11 2014-01-21 Chugai Seiyaku Kabushiki Kaisha Stabilized anti-interleukin-6 antibody-containing preparations
US7425618B2 (en) 2002-06-14 2008-09-16 Medimmune, Inc. Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
KR101159559B1 (ko) 2003-08-05 2012-06-26 노보 노르디스크 에이/에스 신규의 인슐린 유도체
DE202004020676U1 (de) 2004-03-10 2005-11-10 Bioceuticals Arzneimittel Ag Erythropoietin-Flüssigformulierung
US20090074882A1 (en) 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
WO2008152106A1 (en) 2007-06-13 2008-12-18 Novo Nordisk A/S Pharmaceutical formulation comprising an insulin derivative
MX385591B (es) 2008-08-15 2025-03-18 Ironwood Pharmaceuticals Inc Formulaciones que contienen linaclotida para administracion oral.
CA2738615A1 (en) 2008-10-30 2010-05-06 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
CA2742659C (en) * 2008-11-04 2016-09-27 Aska Pharmaceutical Co., Ltd. Aqueous composition containing follicle-stimulating hormone
WO2011017502A2 (en) 2009-08-06 2011-02-10 Ironwood Pharmaceuticals, Inc. Linaclotide-containing formulations for oral administration
TWI505838B (zh) * 2010-01-20 2015-11-01 中外製藥股份有限公司 Stabilized antibody solution containing
CN102869677B (zh) 2010-02-17 2015-07-08 硬木药品公司 胃肠病症的治疗
CA2808091C (en) 2010-08-11 2019-05-21 Ironwood Pharmaceuticals, Inc. Stable formulations of linaclotide
JP6049625B2 (ja) 2010-10-27 2016-12-21 ノヴォ ノルディスク アー／エス 様々な注射間隔を用いて施されるインスリン注射を使用する、真性糖尿病の治療
EP2699265B1 (en) 2011-04-20 2019-10-16 Sandoz AG STABLE PHARMACEUTICAL LIQUID FORMULATIONS OF THE FUSION PROTEIN TNFR:Fc
JP6312592B2 (ja) 2011-08-17 2018-04-18 アイアンウッド ファーマシューティカルズ インコーポレイテッド 消化器疾患の治療
US10493151B2 (en) 2011-10-18 2019-12-03 Coherus Biosciences, Inc. Etanercept formulations stabilized with sodium chloride
CN104011073B (zh) 2011-10-18 2017-08-25 科荣生生物科学公司 使用氨基酸稳定的依那西普制剂
RS57013B1 (sr) 2012-09-11 2018-05-31 Coherus Biosciences Inc Korektno savijeni etanercept sa visokom čistoćom i odličnim prinosom
WO2014177623A1 (en) 2013-04-30 2014-11-06 Novo Nordisk A/S Novel administration regime
CN105012232B (zh) * 2015-08-14 2017-09-05 北京世桥生物制药有限公司 一种胸腺五肽注射液及其制作方法
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
CN113453661A (zh) * 2018-12-21 2021-09-28 艾瑞克有限公司 新组合物
CN114096269B (zh) 2019-07-12 2024-06-11 诺和诺德股份有限公司 高浓度胰岛素制剂
CN115697404A (zh) 2020-05-29 2023-02-03 中外制药株式会社 含有抗体的制剂
US20240366731A1 (en) 2021-08-12 2024-11-07 Celagenex Research (India) Pvt. Ltd. Oral algal oil based gastro-intestinal tract permeable peptide composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4190646A (en) * 1975-11-11 1980-02-26 Sloan-Kettering Institute For Cancer Research Polypeptide compositions and methods
JPS57169425A (en) * 1981-04-10 1982-10-19 Eisai Co Ltd Composition and method for preventing adsorption of secretin
EP0082481B2 (en) * 1981-12-23 1990-09-12 Schering Corporation Stabilised alpha-interferon formulations and their preparation
DE3583880D1 (de) * 1984-04-09 1991-10-02 Takeda Chemical Industries Ltd Stabile interleukin-2-zusammensetzung.
US4749690A (en) * 1986-01-27 1988-06-07 Ortho Pharmaceutical Corporation Treatment of allergy with thymopentin
US4898826A (en) * 1987-12-10 1990-02-06 Invitron Corporation Method to solubilize tissue plasminogen activator

Also Published As

Publication number Publication date
EP0420649A2 (en) 1991-04-03
EP0420649A3 (en) 1991-07-31
IE903475A1 (en) 1991-04-10
PT95451A (pt) 1991-05-22
NZ235324A (en) 1992-07-28
AU6446790A (en) 1991-04-28
WO1991004743A1 (en) 1991-04-18
DD298053A5 (de) 1992-02-06
ZA907492B (en) 1991-10-30
IT9019421A0 (it) 1990-02-20
JPH04502017A (ja) 1992-04-09
IT9019421A1 (it) 1991-03-29
HUT59013A (en) 1992-04-28
HU907939D0 (en) 1991-08-28
IL95663A0 (en) 1991-06-30
CA2026149A1 (en) 1991-03-29
BR9006934A (pt) 1991-10-22

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