KR100615389B1 - 다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 예방 및 개선용 건강 기능 식품 - Google Patents
다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 예방 및 개선용 건강 기능 식품 Download PDFInfo
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Images
Classifications
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- A—HUMAN NECESSITIES
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- A23V2200/304—Foods, ingredients or supplements having a functional effect on health having a modulation effect on allergy and risk of allergy
Abstract
Description
LPS 자극 | 처리 | IgE(IU/㎖) |
- | 배지 | 187.8 ±8.4 |
+ | 배지 | 392.9 ±3.4 |
+ | 다래 열수추출물 | 228.8 ±7.1 |
+ | 개다래 열수추출물 | 233.2 ±5.8 |
+ | 취다래 열수추출물 | 211.7 ±7.9 |
+ | 다래 줄기 열수추출물 | 241.5 ±5.8 |
+ | 30% 에탄올 열수추출물 | 306.2 ±16.5 |
+ | 50% 에탄올 열수추출물 | 266.8 ±17.0 |
+ | 70% 에탄올 열수추출물 | 201.9 ±27.6 |
+ | 덱사메타손 | 203.6 ±30.9 |
LPS 자극 | 처리 | IgE (IU/㎖) |
- | 배지 | 117.4±7.6 |
+ | 배지 | 212.5 ±11.8 |
+ | 다래 열수추출물 | 151.7 ±11.9 |
+ | 클로로포름 분획 | 206.7 ±15.6 |
+ | 에틸아세테이트 분획 | 123.3 ±8.1 |
+ | 물 분획 | 218.9 ±13.3 |
+ | 덱사메타손 | 138.9 ±2.1 |
LPS 자극 | 처리 | IgE (IU/㎖) |
- | 배지 | 379.7 ±13.2 |
+ | 배지 | 540.4 ±35.1 |
+ | 에틸아세테이트 분획 | 298.1 ±9.7 |
+ | 실리카겔 분획 1 | 293.5 ±12.5 |
+ | 실리카겔 분획 2 | 307.6 ±24.1 |
+ | 실리카겔 분획 3 | 453.1 ±17.3 |
+ | 실리카겔 분획 4 | 396.9 ±26.8 |
+ | 덱사메타손 | 277.6 ±12.4 |
정상마우스 | 음용수 | 다래추출물 | 덱사메타손 | |
IgE | 1.0 ±0.0 | 7.6 ±0.2 | 2.2 ±0.5 | 2.0 ±0.6 |
IgG1 | 1.0 ±0.0 | 5.1 ±0.1 | 3.3 ±0.3 | 3.1 ±0.3 |
IgG2a | 1.0 ±0.1 | 2.1 ±0.4 | 4.6 ±0.3 | 1.9 ±0.4 |
IgG2b | 1.0 ±0.0 | 1.4 ±0.1 | 1.5 ±0.2 | 1.2 ±0.1 |
정상마우스 | OVA 감작 마우스 | |||
음용수 | 다래추출물 | 덱사메타손 | ||
IL-4 | 21.6 ±11.8 | 159.5 ±15.7 | 76.5 ±10.0 | 23.1 ±8.7 |
IL-5 | 0.5 ±0.8 | 2573.6 ±42.0 | 1638.3 ±33.3 | 884.1 ±80.7 |
IL-12 | 1626.0 ±58.5 | 906.2 ±66.0 | 1321.2 ±92.4 | 297.7 ±16.4 |
인터페론-감마 | 14.1 ±19.6 | 1016.0 ±25.6 | 1688.2 ±15.8 | 470.5 ±38.6 |
단위: pg/㎖ |
PHA 자극 | 처리 | IL-5 | IL-13 | IL-10 | 인터페론-감마 |
- | - | 92.2 ±6.4 | 0 ±0 | 0 ±0 | 53.3 ±30.2 |
+ | 배지 | 518.1 ±120.3 | 667.8 ±46.5 | 480.3 ±15.3 | 334.1 ±277.7 |
+ | 다래추출물 | 248.5 ±62.0 | 355.7 ±93.1 | 570.2 ±56.3 | 1067 ±345.1 |
단위: pg/㎖ |
1 일 | 14 일 | 28 일 | 42 일 | |
알러지 환자 K | 950.8 IU/㎖ | 855.6 IU/㎖ | 679.1 IU/㎖ | 266.1 IU/㎖ |
알러지 환자 E | 278.3 IU/㎖ | 236.0 IU/㎖ | 189.2 IU/㎖ | 95.0 IU/㎖ |
처리 | 크로몰린(대조군) | 다래 추출물 |
저해율(%) | 52 ±13 | 44 ±10 |
처리 | 부종지수(㎎) | 저해율(%) |
대조군 | 7.2 ±1.1 | - |
다래 추출물 | 2.7 ±0.8 | 62.5 |
인도메타신 | 1.3 ±0.3 | 81.9 |
IgE | IgG1 | IgG2a | |
음용수 | 1572.9 ±77.4 | 242.2 ±14.2 | 177.5 ±17.2 |
다래열수추출물 | 699.0 ±348.5 | 263.4 ±21.1 | 263.5 ±16.2 |
덱사메타손 | 130.0 ±55.3 | 247.3 ±10.8 | 148.0 ±14.8 |
단위: pg/㎖ |
IL-4 | IL-5 | IL-12 | 인터페론 감마 | |
음용수 | 151.9 ±2.2 | 778.3 ±34.1 | 1925.7 ±134.5 | 10407.5 ±130.8 |
다래열수추출물 | 24.1 ±5.2 | 248.0 ±17.8 | 2346.2 ±98.4 | 15847.9 ±1693.1 |
덱사메타손 | 42.7 ±19.4 | 646.5 ±51.7 | 201.2 ±12.1 | 10096.4 ±192.4 |
단위: ng/㎖ |
Claims (9)
- 다래 (Actinidia arguta) 과실 물, 에탄올 또는 이들의 혼합용매 가용추출물 및 식품학적으로 첨가 가능한 식품보조첨가제를 포함하는 알러지 질환의 예방 및 개선용 건강 기능 식품.
- 삭제
- 삭제
- 삭제
- 삭제
- 삭제
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- 삭제
- 삭제
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US40529502P | 2002-08-23 | 2002-08-23 | |
US60/405,295 | 2002-08-23 |
Publications (2)
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KR20040018117A KR20040018117A (ko) | 2004-03-02 |
KR100615389B1 true KR100615389B1 (ko) | 2006-08-25 |
Family
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Application Number | Title | Priority Date | Filing Date |
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KR1020030035530A KR100615389B1 (ko) | 2002-08-23 | 2003-06-03 | 다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 예방 및 개선용 건강 기능 식품 |
KR10-2003-0037515A KR100511550B1 (ko) | 2002-08-23 | 2003-06-11 | 다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 치료 및 예방을 위한 약학 조성물 |
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KR10-2003-0037515A KR100511550B1 (ko) | 2002-08-23 | 2003-06-11 | 다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 치료 및 예방을 위한 약학 조성물 |
Country Status (17)
Country | Link |
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US (2) | US9131722B2 (ko) |
EP (2) | EP2329835B8 (ko) |
JP (3) | JP4620461B2 (ko) |
KR (2) | KR100615389B1 (ko) |
CN (1) | CN1678333B (ko) |
AU (1) | AU2003251197B2 (ko) |
BR (1) | BR0313983A (ko) |
CA (1) | CA2495542C (ko) |
CL (1) | CL2004002241A1 (ko) |
ES (1) | ES2428079T3 (ko) |
HK (1) | HK1076054A1 (ko) |
IL (1) | IL167036A (ko) |
MX (1) | MXPA05002087A (ko) |
NZ (2) | NZ574363A (ko) |
RU (1) | RU2317821C2 (ko) |
WO (1) | WO2004017982A1 (ko) |
ZA (1) | ZA200501666B (ko) |
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US20100111927A1 (en) * | 2002-08-23 | 2010-05-06 | Sunyoung Kim | Compositions Comprising Actinidia and Methods of Use Thereof |
KR100615389B1 (ko) | 2002-08-23 | 2006-08-25 | (주)헬릭서 | 다래 추출물을 함유하는 알러지성 질환 및 비알러지성염증 질환의 예방 및 개선용 건강 기능 식품 |
CA2531988C (en) | 2003-08-05 | 2016-06-28 | Novo Nordisk A/S | Novel insulin derivatives |
NZ532254A (en) * | 2004-04-08 | 2006-03-31 | Dragon Pacific Ltd | Kiwifruit extract and a method for producing powdered kiwifruit extract |
ATE547112T1 (de) * | 2004-08-10 | 2012-03-15 | Helixir Co Ltd | Zusammensetzung aus dem extrakt von actinidia arguta zur prävention und behandlung von alopezie und seborrhöischen hauterkrankungen |
JP4717413B2 (ja) * | 2004-10-22 | 2011-07-06 | 森永乳業株式会社 | 脂質代謝改善用組成物 |
US20080175888A1 (en) * | 2005-02-25 | 2008-07-24 | Julie Lindemann | Combination Therapy Comprising Actinidia and Steroids and Uses Thereof |
AU2006218875B2 (en) * | 2005-02-25 | 2012-08-09 | Efficas, Inc. | Compositions comprising Actinidia and methods of use thereof |
US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
PT1969004E (pt) | 2005-12-28 | 2011-11-25 | Novo Nordisk As | Composições que compreendem uma insulina acilada e zinco e método para criar tais composições |
JP5462430B2 (ja) * | 2006-01-19 | 2014-04-02 | オリザ油化株式会社 | 抗炎症剤及び鎮痛剤 |
AT503521A1 (de) | 2006-05-05 | 2007-11-15 | Omnica Gmbh | Verwendung eines extraktes von kiwi-frucht |
KR101310981B1 (ko) * | 2006-06-05 | 2013-09-25 | 충북대학교 산학협력단 | 괴각 추출물을 유효성분으로 함유하는 알레르기 질환의예방 및 개선용 조성물 |
US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
JP5306605B2 (ja) * | 2007-03-12 | 2013-10-02 | 株式会社ノエビア | 皮膚外用剤 |
US20100143319A1 (en) * | 2007-05-03 | 2010-06-10 | Vital Food Processors Limited | Kiwifruit compositions |
KR100880712B1 (ko) * | 2007-05-17 | 2009-02-02 | 건국대학교 산학협력단 | 탄닌 함유 목천료자 추출물을 유효성분으로 하는 소염 진통제 조성물 |
WO2008152106A1 (en) | 2007-06-13 | 2008-12-18 | Novo Nordisk A/S | Pharmaceutical formulation comprising an insulin derivative |
JP5710091B2 (ja) * | 2007-08-20 | 2015-04-30 | 丸善製薬株式会社 | No産生促進剤 |
WO2009114828A1 (en) * | 2008-03-13 | 2009-09-17 | Childrens Hospital Medical Center | Compositions and methods relating to gastrointestinal allergic conditions |
US9603904B2 (en) | 2008-10-30 | 2017-03-28 | Novo Nordisk A/S | Treating diabetes melitus using insulin injections with less than daily injection frequency |
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