BRPI0407680A - métodos para diagnóstico de cáncer e diminuição de metástase por células cancerosas - Google Patents

métodos para diagnóstico de cáncer e diminuição de metástase por células cancerosas

Info

Publication number
BRPI0407680A
BRPI0407680A BRPI0407680-0A BRPI0407680A BRPI0407680A BR PI0407680 A BRPI0407680 A BR PI0407680A BR PI0407680 A BRPI0407680 A BR PI0407680A BR PI0407680 A BRPI0407680 A BR PI0407680A
Authority
BR
Brazil
Prior art keywords
cancer
methods
cell metastasis
diagnosis
cancer cell
Prior art date
Application number
BRPI0407680-0A
Other languages
English (en)
Inventor
James P Quigley
John D Hooper
Jacqueline E Testa
Original Assignee
Novartis Ag
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32908657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0407680(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Scripps Research Inst filed Critical Novartis Ag
Publication of BRPI0407680A publication Critical patent/BRPI0407680A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Abstract

"MéTODOS PARA DIAGNóSTICO DE CáNCER E DIMINUIçãO DE METáSTASE POR CéLULAS CANCEROSAS". A presente invenção refere-se a uma proteína que é uma proteína marcadora de tumor. Essa proteína pode ser usada para preparar anticorpos que se ligam à proteína marcadora de tumor. Esses anticorpos podem ser usados para reduzir ou eliminar metástase por células de câncer que produzem a proteína marcadora de tumor. Ainda, a invenção provê métodos que podem ser usados para diagnosticar cáncer e metástase por células de câncer.
BRPI0407680-0A 2003-02-19 2004-02-18 métodos para diagnóstico de cáncer e diminuição de metástase por células cancerosas BRPI0407680A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44882803P 2003-02-19 2003-02-19
PCT/EP2004/001556 WO2004074481A1 (en) 2003-02-19 2004-02-18 Glycorpotein antigen sima135 expressed in metastatic human tumor cells

Publications (1)

Publication Number Publication Date
BRPI0407680A true BRPI0407680A (pt) 2006-03-01

Family

ID=32908657

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0407680-0A BRPI0407680A (pt) 2003-02-19 2004-02-18 métodos para diagnóstico de cáncer e diminuição de metástase por células cancerosas

Country Status (13)

Country Link
US (4) US7589173B2 (pt)
EP (1) EP1597367B1 (pt)
JP (3) JP2007523836A (pt)
CN (1) CN100422328C (pt)
AT (1) ATE473279T1 (pt)
AU (1) AU2004213568A1 (pt)
BR (1) BRPI0407680A (pt)
CA (2) CA2787820A1 (pt)
DE (1) DE602004027992D1 (pt)
ES (1) ES2349128T3 (pt)
MX (1) MXPA05008794A (pt)
PT (1) PT1597367E (pt)
WO (1) WO2004074481A1 (pt)

Families Citing this family (22)

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DE10242146A1 (de) * 2002-09-04 2004-03-18 Eberhard-Karls-Universität Tübingen Universitätsklinikum Antikörper zur Identifizierung und/oder Isolierung von hämatopoetischen Stammzellen
CN100422328C (zh) * 2003-02-19 2008-10-01 诺瓦提斯公司 在人转移性肿瘤细胞中表达的糖蛋白抗原sima135
EP1660531A2 (en) 2003-08-05 2006-05-31 Novo Nordisk A/S Novel insulin derivatives
GB0324656D0 (en) * 2003-10-22 2003-11-26 Celltech R&D Ltd A protein involved in ovarian cancer
US20080008719A1 (en) * 2004-07-10 2008-01-10 Bowdish Katherine S Methods and compositions for the treatment of prostate cancer
WO2006017173A1 (en) * 2004-07-10 2006-02-16 Alexion Pharmaceuticals, Inc. Methods for discovering antibodies specific to cancer cells and antibodies discovered thereby
WO2007005502A2 (en) * 2005-06-30 2007-01-11 Applera Corporation Methods and compositions for treating diseases targeting cdcp1
JP2007112734A (ja) * 2005-10-19 2007-05-10 Chugai Pharmaceut Co Ltd 抗ｃｄｃｐ１抗体を含有する癌細胞増殖抑制剤
EP1969004B1 (en) 2005-12-28 2011-08-10 Novo Nordisk A/S Compositions comprising an acylated insulin and zinc and method of making the said compositions
US8264715B2 (en) * 2006-04-25 2012-09-11 Ricoh Company, Ltd. Approach for implementing locked printing with remote unlock on printing devices
US20130136689A1 (en) * 2007-06-05 2013-05-30 Christian Rohlff Proteins
DK2447719T3 (en) * 2007-02-26 2016-10-10 Oxford Biotherapeutics Ltd proteins
WO2008152106A1 (en) 2007-06-13 2008-12-18 Novo Nordisk A/S Pharmaceutical formulation comprising an insulin derivative
WO2010049488A1 (en) 2008-10-30 2010-05-06 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
TW201113037A (en) 2009-08-28 2011-04-16 Hoffmann La Roche Antibodies against CDCP1 for the treatment of cancer
TWI412375B (zh) 2009-08-28 2013-10-21 Roche Glycart Ag 人類化抗ｃｄｃｐ１抗體
RU2013123515A (ru) 2010-10-27 2014-12-10 Ново Нордиск А/С Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами
JP2016519127A (ja) 2013-04-30 2016-06-30 ノヴォ ノルディスク アー／エス 新規投与レジメン
WO2015082446A1 (en) 2013-12-02 2015-06-11 F. Hoffmann-La Roche Ag Treatment of cancer using an anti-cdcp1 antibody and a taxane
MA50134A (fr) 2016-12-16 2020-07-29 Bluefin Biomedicine Inc Anticorps anti-protéine 1 contenant un domaine anti-cub (cdcp1), conjugués anticorps-médicament et leurs méthodes d'utilisation
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
AU2020377402A1 (en) * 2019-11-06 2022-06-23 Commonwealth Scientific And Industrial Research Organisation Binding proteins to CUB domain-containing protein (CDCP1)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69229254T2 (de) * 1991-10-30 1999-09-23 Idemitsu Kosan Co Verfahren zur Herstellung von menschlichen Lymphozyten und menschlichen Antikörpern; und so hergestellte Antikörper
AU4441799A (en) 1998-06-15 2000-01-05 Research Foundation Of The State University Of New York, The Monoclonal antibodies that recognize antigens associated with tumor metastasis
JP2002521055A (ja) * 1998-07-30 2002-07-16 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ９８個のヒト分泌タンパク質
WO2002004508A1 (de) 2000-07-07 2002-01-17 Boehringer Ingelheim International Gmbh Tumorassoziiertes antigen (b345), gekennzeichnet durch eine aminosäuresequenz wie in seq. id. no. 4
US20020142003A1 (en) * 2000-07-07 2002-10-03 Norbert Schweifer Tumor-associated antigen (B345)
US6783969B1 (en) * 2001-03-05 2004-08-31 Nuvelo, Inc. Cathepsin V-like polypeptides
CN100422328C (zh) * 2003-02-19 2008-10-01 诺瓦提斯公司 在人转移性肿瘤细胞中表达的糖蛋白抗原sima135
WO2007134272A2 (en) * 2006-05-12 2007-11-22 Janssen Pharmaceutica N.V. Humanized models via targeted mtagenesis with zinc finger nuclease

Also Published As

Publication number Publication date
WO2004074481A1 (en) 2004-09-02
US7589173B2 (en) 2009-09-15
US20040247601A1 (en) 2004-12-09
CA2787820A1 (en) 2004-09-02
US20120039891A1 (en) 2012-02-16
CN1761750A (zh) 2006-04-19
JP2011046712A (ja) 2011-03-10
ATE473279T1 (de) 2010-07-15
ES2349128T3 (es) 2010-12-28
US20130142798A1 (en) 2013-06-06
MXPA05008794A (es) 2006-03-10
JP2013241416A (ja) 2013-12-05
DE602004027992D1 (de) 2010-08-19
CA2516366A1 (en) 2004-09-02
PT1597367E (pt) 2010-09-02
AU2004213568A1 (en) 2004-09-02
EP1597367B1 (en) 2010-07-07
CN100422328C (zh) 2008-10-01
EP1597367A1 (en) 2005-11-23
JP2007523836A (ja) 2007-08-23
US20100158917A1 (en) 2010-06-24
JP5331071B2 (ja) 2013-10-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]