ATE407353T1 - Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben - Google Patents

Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben

Info

Publication number
ATE407353T1
ATE407353T1 AT98940811T AT98940811T ATE407353T1 AT E407353 T1 ATE407353 T1 AT E407353T1 AT 98940811 T AT98940811 T AT 98940811T AT 98940811 T AT98940811 T AT 98940811T AT E407353 T1 ATE407353 T1 AT E407353T1
Authority
AT
Austria
Prior art keywords
vessel
tissue specimens
dehydrated
defatted
fixed
Prior art date
Application number
AT98940811T
Other languages
German (de)
English (en)
Inventor
Ervin Essenfeld
Harold Essenfeld
Azorides Morales
Original Assignee
Univ Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Miami filed Critical Univ Miami
Application granted granted Critical
Publication of ATE407353T1 publication Critical patent/ATE407353T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/50—Clamping means, tongs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36—Embedding or analogous mounting of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44—Sample treatment involving radiation, e.g. heat
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N2001/315—Basket-type carriers for tissues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • General Preparation And Processing Of Foods (AREA)
AT98940811T 1997-08-20 1998-08-19 Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben ATE407353T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5610297P 1997-08-20 1997-08-20

Publications (1)

Publication Number Publication Date
ATE407353T1 true ATE407353T1 (de) 2008-09-15

Family

ID=22002161

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940811T ATE407353T1 (de) 1997-08-20 1998-08-19 Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben

Country Status (12)

Country Link
US (4) US6207408B1 (enExample)
EP (2) EP1005633B1 (enExample)
JP (2) JP4164232B2 (enExample)
KR (1) KR20010023070A (enExample)
AT (1) ATE407353T1 (enExample)
AU (1) AU746497B2 (enExample)
CA (2) CA2301924C (enExample)
DE (1) DE69839963D1 (enExample)
DK (1) DK1005633T3 (enExample)
ES (1) ES2313752T3 (enExample)
TW (1) TW571100B (enExample)
WO (1) WO1999009390A1 (enExample)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451551B1 (en) * 1994-03-11 2002-09-17 Biogenex Laboratories Releasing embedding media from tissue specimens
US6793890B2 (en) 1997-08-20 2004-09-21 The University Of Miami Rapid tissue processor
KR20010023070A (ko) 1997-08-20 2001-03-26 더 유니버시티 오브 마이애미 고품질의 연속적인 재료 처리, 조직 고정-탈수-지방제거-함침 방법
US7075640B2 (en) 1997-10-01 2006-07-11 Arcturus Bioscience, Inc. Consumable for laser capture microdissection
WO2000000813A1 (en) * 1998-06-30 2000-01-06 Lamina, Inc. Cytological and histological fixative composition and methods of use
EP1210577A2 (en) * 1999-04-29 2002-06-05 Arcturus Engineering, Inc. Processing technology for lcm samples
US7897106B2 (en) * 1999-07-08 2011-03-01 Lee Angros Situ heat induced antigen recovery and staining apparatus and method
EP1208378B9 (en) 1999-07-08 2014-12-10 Lee H. Angros Antigen recovery and/or staining apparatus and method
US7951612B2 (en) * 1999-07-08 2011-05-31 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
US8298485B2 (en) * 1999-07-08 2012-10-30 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
US6916608B2 (en) * 1999-09-10 2005-07-12 Becton, Dickinson And Company Composition for providing long term stability to cells for diagnostic testing
DE19945621A1 (de) * 1999-09-23 2001-04-05 Aurel Popa Geräteanordnung zur Präparation und Analyse von Gewebe für mirkoskopische Untersuchungen
WO2001044783A1 (en) * 1999-12-14 2001-06-21 University Of Miami Rapid tissue processor
DK1292818T3 (en) 2000-06-09 2016-04-11 Univ Miami Pathology board for rough cut
CN1488002A (zh) * 2000-12-01 2004-04-07 ��˹��ŵ�� 测定表皮生长因子受体和HER2-neu的基因表达及其水平与存活率之间相关性的方法
US7049059B2 (en) * 2000-12-01 2006-05-23 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression
US6582919B2 (en) 2001-06-11 2003-06-24 Response Genetics, Inc. Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates
US6602670B2 (en) 2000-12-01 2003-08-05 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 expression
US6518416B1 (en) 2000-12-01 2003-02-11 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 expression
US6956111B2 (en) * 2001-03-02 2005-10-18 Response Genetics, Inc. Method of determining dihydropyrimidine dehydrogenase gene expression
US6458598B1 (en) * 2001-08-13 2002-10-01 Dako A/S Process for preparing and presenting a tissue sample for histological study
CN100359313C (zh) * 2001-09-20 2008-01-02 王世峰 一种活体组织脱水盒
JP2005504323A (ja) * 2001-10-01 2005-02-10 ヴィジョン バイオシステムズ リミテッド 組織学的組織標本処理
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
US6797928B2 (en) * 2002-04-23 2004-09-28 Ted Pella, Inc. Method and apparatus for the rapid decalcification and fixation of mineralized tissues
US7138226B2 (en) * 2002-05-10 2006-11-21 The University Of Miami Preservation of RNA and morphology in cells and tissues
DE60328186D1 (de) * 2002-05-28 2009-08-13 Diapath S P A Zusammensetzung für die herstellung von histologischen, autopsischen und zytologischen proben
US7179424B2 (en) 2002-09-26 2007-02-20 Biopath Automation, L.L.C. Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor
JP4105164B2 (ja) * 2002-09-26 2008-06-25 バイオパス・オートメーション・エル・エル・シー 組織標本のハンドリングおよび包埋を自動化する機器および方法
CN100518940C (zh) 2002-09-26 2009-07-29 比欧帕斯自动化公司 操作组织样品的盒子、嵌入组件和方法
US7219884B2 (en) * 2002-10-01 2007-05-22 The University Of Miami Pathology grossing tool
US7541161B2 (en) * 2002-10-31 2009-06-02 University Of Massachusetts Method and apparatus for preparing cells for microtome sectioning and archiving nucleic acids and proteins
CA2502580C (en) * 2002-10-31 2013-09-10 University Of Massachusetts Rapid cell block embedding method and apparatus
JP4189484B2 (ja) * 2002-12-12 2008-12-03 国立循環器病センター総長 マイクロ波照射による生体組織の処理方法
WO2004072268A2 (en) * 2003-02-12 2004-08-26 Mayo Foundation For Medical Education And Research Pkhdl1, a homolog of the autosomal recessive kidney disease gene
KR200327028Y1 (ko) * 2003-06-17 2003-09-19 장시창 인체조직검사기구
US8554372B2 (en) 2003-09-29 2013-10-08 Leica Biosystems Melbourne Pty Ltd System and method for histological tissue specimen processing
CA2543043C (en) * 2003-10-24 2013-09-17 The University Of Miami Simplified tissue processing
KR100458860B1 (ko) * 2004-04-22 2004-12-03 송영민 생검시료의 검사를 위한 보조기구
WO2005116609A1 (en) * 2004-05-25 2005-12-08 Vision Biosystems Limited Method of treatment of tissue processing fluid and apparatus therefor
ATE416368T1 (de) * 2004-06-07 2008-12-15 Milestone Srl Verfahren und vorrichtung zur mikrowellen- unterstützten automatischen gewebebehandlung
US7273720B1 (en) 2004-12-02 2007-09-25 Collaborative Laboratory Services, Llc Rapid tissue processing method and apparatus
US8236255B2 (en) * 2004-12-02 2012-08-07 Lab Vision Corporation Slide treatment apparatus and methods for use
US7273587B1 (en) 2004-12-02 2007-09-25 Collaborative Laboratory Services, Llc Rapid tissue processing method and apparatus
CA2764294C (en) 2004-12-17 2013-12-24 Ventana Medical Systems, Inc. Methods and compositions for a microemulsion-based tissue treatment
GB0501590D0 (en) * 2005-01-25 2005-03-02 Ceres Power Ltd Processing of enhanced performance LSCF fuel cell cathode microstructure and a fuel cell cathode
US20060228772A1 (en) * 2005-04-11 2006-10-12 Donndelinger Thomas M Compositions and methods for preparing specimens for microscopic analysis
CN101203597A (zh) * 2005-04-21 2008-06-18 塞莱勒斯诊断公司 用于自动快速免疫组织化学的芯吸盒方法和设备
EP1888739B1 (en) 2005-05-24 2021-08-11 Lee H. Angros Automated apparatus and method for treating biological specimens on slides
KR101289256B1 (ko) * 2005-06-28 2013-07-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 오클라호마 탄소 나노튜브의 성장 및 수득 방법
WO2007016935A1 (en) 2005-07-29 2007-02-15 Histogenex Nv Methods, reagents and instrumentation for preparing impregnated tissue samples suitable for histopathological and molecular studies
US20070116612A1 (en) * 2005-11-02 2007-05-24 Biopath Automation, L.L.C. Prefix tissue cassette
US7769962B2 (en) * 2005-12-12 2010-08-03 Jeda Technologies, Inc. System and method for thread creation and memory management in an object-oriented programming environment
EP1804045B1 (de) 2005-12-30 2014-03-12 QIAGEN GmbH Ein Verfahren und ein Kit zur Behandlung einer biologischen Probe
EP1977214A2 (en) * 2006-01-13 2008-10-08 Ventana Medical Systems, Inc. Biological sample processing composition and method
WO2007141888A1 (ja) * 2006-06-05 2007-12-13 Jokoh Co., Ltd 生物組織固定装置
US20080026366A1 (en) * 2006-06-07 2008-01-31 Newcomer Supply, Inc. Biological fixative and method of using the biological fixative
AT504371B8 (de) 2006-10-03 2008-09-15 Leica Mikrosysteme Gmbh Vorrichtung zur mikrowellen-gestützten präparation von proben
US7666620B2 (en) * 2006-11-08 2010-02-23 Richard-Allan Scientific Company Rapid tissue processing system
JP5050200B2 (ja) * 2006-11-20 2012-10-17 国立大学法人三重大学 医療検体用ケース
ES2788002T3 (es) * 2006-12-12 2020-10-20 Biopath Automation Llc Soporte de biopsia con material celular resiliente seccionable
EP1965190A1 (en) * 2007-02-27 2008-09-03 Qiagen GmbH Fixation of a biological sample
EP1975595A1 (en) * 2007-03-21 2008-10-01 Diapath S.r.l. Automatic processor for histological samples and its operation
EP2009419B1 (en) * 2007-06-25 2009-12-23 Milestone S.r.l. Measuring the thickness of organic samples
US7906076B2 (en) * 2007-07-02 2011-03-15 University Of Massachusetts Method and apparatus for biopsy sample processing
JP4059520B1 (ja) * 2007-07-25 2008-03-12 株式会社常光 組織片処理装置
EP2187749A4 (en) * 2007-08-14 2011-04-20 Charm Sciences Inc METHOD AND DEVICE FOR CONCENTRATING SAMPLES
ES2422629T3 (es) * 2007-10-23 2013-09-12 Becton Dickinson Co Recipiente para tejido con desplazamiento de fluido para diagnóstico molecular e histológico
AU2013200912B2 (en) * 2007-10-23 2014-04-17 Becton, Dickinson And Company Multi-chambered tissue containment system for molecular and histology diagnostics
EP2214827B1 (en) 2007-10-23 2013-05-22 Becton, Dickinson and Company Multi-chambered tissue containment system for molecular and histology diagnostics
BRPI0817814B1 (pt) 2007-10-23 2019-01-29 Becton Dickinson Co kit de partes, sistema, conjunto e método para armazenar e preservar uma amostra biológica
ES2805503T3 (es) 2007-10-23 2021-02-12 Becton Dickinson Co Recipiente para tejidos para diagnóstico molecular e histológico que incorpora una membrana rompible
WO2009055595A1 (en) 2007-10-23 2009-04-30 Becton, Dickinson And Company Closed kit for tissue containment and stabilization for molecular and histopathology diagnostics
US8158381B2 (en) * 2008-03-27 2012-04-17 Richard-Allan Scientific Company Methods for integrated tissue processing and staining
EP2285979B2 (en) 2008-05-27 2020-02-19 Dako Denmark A/S Hybridization compositions and methods
US20090298172A1 (en) 2008-05-28 2009-12-03 Steven Paul Wheeler Histological specimen treatment apparatus and method
US20090325273A1 (en) * 2008-06-30 2009-12-31 Chin Pin Chang Chien Multi-functional treating device for treating pathological tissue sections
EP2316010B1 (en) * 2008-08-27 2022-03-16 The University of Miami Tissue cassette and method for preparing tissue samples
WO2010025425A1 (en) 2008-08-29 2010-03-04 Angros Lee H Multiplexed microscope slide staining apparatus
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
WO2010056883A1 (en) 2008-11-12 2010-05-20 Ventana Medical Systems, Inc. Methods and apparatuses for heating slides carrying specimens
CA2745431A1 (en) 2008-12-03 2010-06-10 Timothy J. O'leary Pressure-assisted molecular recovery (pamr) of biomolecules, pressure-assisted antigen retrieval (paar), and pressure-assisted tissue histology (path)
CA2749135C (en) 2009-01-22 2017-04-18 Biopath Automation, L.L.C. Microtome sectionable biopsy support for orienting tissue samples
WO2010097655A1 (en) * 2009-02-26 2010-09-02 Dako Denmark A/S Compositions and methods for rna hybridization applications
US8640357B2 (en) * 2009-03-23 2014-02-04 Hasan Huseyin Engin Laboratory type quick film drying oven
DE102009025574A1 (de) * 2009-06-19 2010-12-23 Leica Biosystems Nussloch Gmbh Verfahren zum automatischen Bearbeiten von Gewebeproben in einem Gewebeprozessor
US9237608B2 (en) 2009-08-14 2016-01-12 Cem Corporation Pressure stepped microwave assisted digestion
EP2467694B1 (en) * 2009-08-21 2015-01-07 Roche Diagnostics GmbH Use of a bis-maleic anhydride cross-linking agent for fixation of a cell or tissue sample
US10539487B2 (en) 2010-03-04 2020-01-21 Ventana Medical Systems, Inc. Systems and methods for monitoring tissue sample processing
US10126216B2 (en) 2011-02-17 2018-11-13 Ventana Medical Systems, Inc. Method for tissue sample fixation
US10267769B2 (en) 2010-03-04 2019-04-23 Ventana Medical Systems, Inc. Processing system for processing specimens using acoustic energy
US8227233B2 (en) * 2010-06-09 2012-07-24 Ford Global Technologies, Llc Method of making foamed mycelium structure
US20120171694A1 (en) * 2010-07-30 2012-07-05 Vermillion, Inc. Predictive markers and biomarker panels for ovarian cancer
DE102011055120B4 (de) * 2011-04-20 2016-04-14 Leica Biosystems Nussloch Gmbh Verfahren zur Verarbeitung zumindest einer histologischen Probe und Vorrichtung zum Behandeln einer histologischen Probe.
GB2490202B (en) * 2011-04-20 2015-06-24 Leica Biosystems Nussloch Gmbh Method of detaching and/or isolating a histological sample
US10444124B2 (en) 2011-05-20 2019-10-15 Riken Clarifying reagent for biological materials and use thereof
US8920720B2 (en) * 2011-06-03 2014-12-30 Rushabh Instruments, Inc. Rotary tissue processor with configurable stations
RU2499242C2 (ru) * 2011-08-29 2013-11-20 Андрей Викторович Иванченко Способ подготовки образцов биологических тканей к гистологическим исследованиям
JP6189306B2 (ja) * 2011-09-29 2017-08-30 ザ ユニバーシティ オブ マイアミＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍｉａｍｉ 凍結切片の代用としての超迅速診断用組織調製法
WO2013046033A1 (en) 2011-09-30 2013-04-04 Dako Denmark A/S Hybridization compositions and methods using formamide
EP3252173A1 (en) 2011-10-21 2017-12-06 Dako Denmark A/S Hybridization compositions and methods
US20140341871A1 (en) * 2011-12-30 2014-11-20 Paul R. Morris Regenerative tissue matrix
CA2876682A1 (en) 2012-06-22 2013-12-27 Leica Biosystems Nussloch Gmbh Biopsy tissue sample transport device and method of using thereof
WO2013192607A1 (en) 2012-06-22 2013-12-27 Leica Biosystems Nussloch Gmbh Tissue sample container and methods
JP6274443B2 (ja) * 2012-10-30 2018-02-07 学校法人金沢医科大学 透明化生物標本作製用キット及び透明化生物標本作製方法
US9052256B2 (en) 2013-03-15 2015-06-09 Leica Biosystems Nussloch Gmbh Method for processing and embedding tissue
CA2845832C (en) 2013-03-15 2020-09-22 Leica Biosystems Nussloch Gmbh Tissue cassette with biasing element
US9097629B2 (en) 2013-03-15 2015-08-04 Leica Biosystems Nussloch Gmbh Tissue cassette with retractable member
EP3035026A4 (en) 2013-08-14 2017-04-26 Riken Composition for preparing biomaterial with excellent light-transmitting property, and use thereof
WO2015085175A1 (en) * 2013-12-05 2015-06-11 Shidham Vinod B Cell blocks for cytopathology and surgical pathology specimens
US9733162B2 (en) * 2014-02-11 2017-08-15 Ihor Turkevych Universal system, method and solution for the acceleration of the process of fixing, dehydrating and clearing the structure of biological tissue
US9766171B2 (en) 2014-03-17 2017-09-19 Columbia Insurance Company Devices, systems and method for flooring performance testing
CN106211762B (zh) 2014-04-04 2020-08-14 麻省理工学院 向带电基质中、在带电基质中和/或从带电基质中主动转运带电分子
US10591392B2 (en) 2014-07-03 2020-03-17 Applikate Technologies Llc Simultaneous dehydration and staining of tissue for deep imaging
JP6383619B2 (ja) * 2014-09-22 2018-08-29 株式会社トスカバノック 病理検体の管理方法
JP6781421B2 (ja) * 2015-03-18 2020-11-04 国立研究開発法人理化学研究所 生物材料の観察方法および透明化方法
US10365189B2 (en) 2015-05-07 2019-07-30 Steven Wheeler Histological specimen treatment
US12366508B2 (en) 2015-07-30 2025-07-22 Qiagen Gmbh Method of preparing a frozen biological sample
KR101765460B1 (ko) * 2016-01-11 2017-08-07 주식회사 메딕슨 카트리지형 극초단파 생체시료 고정장치
CN105606437B (zh) * 2016-03-01 2018-06-19 青岛锴锦医疗器械有限公司 一种快速病理组织脱水机
ITUA20162517A1 (it) * 2016-04-12 2017-10-12 Andrea Fantozzi Composizione per la conservazione/fissazione di materiale biologico
CN106053126A (zh) * 2016-05-27 2016-10-26 中国水产科学研究院淡水渔业研究中心 一种福瑞鲤成熟卵巢组织冷冻切片的制作方法
KR101866249B1 (ko) 2016-11-29 2018-06-12 박순현 생체 조직 투명화용 조성물 및 이를 이용한 생체 조직 투명화 방법
TWI616525B (zh) * 2017-01-26 2018-03-01 Scl Biotech Ltd 初代細胞萃取設備及其使用方法
JP7028979B2 (ja) * 2017-12-29 2022-03-02 エフ．ホフマン－ラ ロシュ アーゲー 組織試料調製システム
CN108344608B (zh) * 2018-02-09 2021-06-22 李西启 一种快速微波病理组织处理专用试剂及其制备方法
CN108387421B (zh) * 2018-02-09 2021-05-07 青岛锴锦医疗器械有限公司 一种用于病理切片的新型环保快速组织处理液
CN108387419A (zh) * 2018-02-09 2018-08-10 青岛锴锦医疗器械有限公司 一种新型环保快速生物组织处理液
CN110954385B (zh) * 2019-12-17 2021-05-25 李惠 一种病理组织脱水仪
GB2600091B (en) * 2020-10-12 2025-02-19 Cellpath Ltd Cassette assembly and processing method
RU209703U1 (ru) * 2021-07-15 2022-03-18 Федеральное государственное автономное образовательное учреждение высшего образования «Дальневосточный федеральный университет» (ДВФУ) Инкубационная установка для длительного содержания переживающих срезов
WO2023076000A1 (en) * 2021-11-01 2023-05-04 Novodiax, Inc. A method and apparatus for rapid circulating tissue pretreatment
CN114295446B (zh) * 2021-12-28 2024-07-09 中国林业科学研究院木材工业研究所 一种利用包埋剂改善木质文物脆裂的徒手切片方法
CN117147251B (zh) * 2023-08-16 2024-04-26 四川大学 一种人类离体牙髓组织透明化方法

Family Cites Families (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2698809A (en) * 1955-01-04 Preserving plant and animal tissues
US2150757A (en) 1937-06-22 1939-03-14 Agfa Ansco Corp Film drier
US2684925A (en) 1949-03-16 1954-07-27 Technicon Chemical Company Inc Liquid for treating tissue in histologic processing
US3546334A (en) * 1965-05-21 1970-12-08 Lerner Lab Inc Composition for fixing and protecting a smear of body cells and method of applying same
US3389052A (en) 1965-11-02 1968-06-18 Ehrenreich Theodore Fixing and drying cytological smears
GB1321712A (en) * 1970-03-17 1973-06-27 Shandon Elliott Ltd Sequential processing apparatus for processing an article by immersion
US3961097A (en) 1971-10-28 1976-06-01 Gravlee Jr Joseph F Method of preparing tissue for microscopic examination
GB1454510A (en) 1973-05-22 1976-11-03 Tetronics Research Dev Co Ltd Laying blood traces
US3892197A (en) 1974-04-22 1975-07-01 Thomas D Kinney Light microscopy processing apparatus
FR2320544A1 (fr) 1975-08-08 1977-03-04 Gen Electric Formulation et procede de coloration et de scellement d'un echantillon biologique
US4199558A (en) 1976-04-07 1980-04-22 Shandon Southern Products Limited Tissue processing method
US4099483A (en) 1976-04-07 1978-07-11 Shandon Southern Products Limited Tissue processing apparatus
US4141312A (en) 1977-05-16 1979-02-27 Fisher Scientific Company Apparatus for histological tissue processing
US4221823A (en) 1978-04-21 1980-09-09 Phillips Petroleum Company Process for mounting palynological specimens
DE2906650A1 (de) 1979-02-21 1980-08-28 Pfrimmer Pharma Verfahren zur herstellung von transplantatkonserven
US4670386A (en) * 1980-05-23 1987-06-02 Stephen Sugaar Cancer tests using tumor antigen generated lymphokines and compositions
US4578282A (en) * 1982-02-04 1986-03-25 Harrison James S Composition for diagnostic reagents
JPS58219167A (ja) 1982-06-15 1983-12-20 Sumitomo Chem Co Ltd 置換フェニルヒダントイン誘導体およびそれを有効成分とする除草剤
JPS5973A (ja) 1982-06-25 1984-01-05 立花　俊郎 超音波搬送管
US4545831A (en) 1982-09-13 1985-10-08 The Mount Sinai School Of Medicine Method for transferring a thin tissue section
US4681996A (en) 1982-12-16 1987-07-21 Cem Corporation Analytical process in which materials to be analyzed are directly and indirectly heated and dried by microwave radiation
DE3319564A1 (de) 1983-05-30 1984-12-06 Arthur Pfeiffer Vakuumtechnik Wetzlar Gmbh, 6334 Asslar Verfahren zur herstellung flexibler, dauerhaltbargemachter nicht konservierter und konservierter biologischer materialien
JPS6025973A (ja) 1983-07-20 1985-02-08 Chisso Corp ピリミジン類
DE8509640U1 (de) * 1985-03-30 1985-05-30 AGW Analysen-Geräte GmbH, 7970 Leutkirch Küvette
SE8501959L (sv) * 1985-04-23 1986-10-24 Henrik Gerhard Renvall Framstellning av ett vevnadspreparat
US4839194A (en) * 1985-07-05 1989-06-13 Bone Diagnostic Center Methods of preparing tissue samples
US5023187A (en) 1985-09-13 1991-06-11 Fisher Scientific Company Method and device for accelerated treatment of thin sample on surface
US4820504A (en) * 1986-02-12 1989-04-11 City Of Hope Multi-specimen tissue blocks and slides
US4656047A (en) * 1986-03-06 1987-04-07 Kok Lanbrecht P Rapid method for cell block preparation
JPH0525347Y2 (enExample) 1986-07-04 1993-06-25
US4835354A (en) 1987-03-30 1989-05-30 Cem Corporation Microwave heating apparatus for laboratory analyses
FR2616273B1 (fr) 1987-06-05 1989-10-20 Thomson Csf Resonateur hyperfrequence en mode de chuchotement en galerie
US5782897A (en) 1987-06-26 1998-07-21 Microwave Medical Systems, Inc. Microwave heating apparatus for rapid tissue fixation
US4857300A (en) * 1987-07-27 1989-08-15 Cytocorp, Inc. Cytological and histological fixative formulation and methods for using same
US4882128A (en) 1987-07-31 1989-11-21 Parr Instrument Company Pressure and temperature reaction vessel, method, and apparatus
US4946669A (en) 1987-10-09 1990-08-07 Siegfried Barry A Histological fixatives
US4911915A (en) 1987-10-13 1990-03-27 Richard-Allan Medical Industries Method of processing tissue specimens and dehydrant solvent for use therein
US5544650A (en) 1988-04-08 1996-08-13 Neuromedical Systems, Inc. Automated specimen classification system and method
US4891239A (en) 1988-07-05 1990-01-02 Raytheon Company Method and apparatus for ultrafast microwave tissue fixation
DE68918950T2 (de) 1988-10-10 1995-03-16 Commw Scient Ind Res Org Verfahren und vorrichtung für kontinuierliche chemische reaktionen.
US5104640A (en) 1989-03-17 1992-04-14 Wescor, Inc. Fixative composition for fixing blood smears to slides
PT94279A (pt) 1989-06-07 1991-12-31 Wolfgang Moshammer Processo e dispositivo para a aplicacao de radiacao de microondas a materias que contem agua ou misturadas com agua
US5089288A (en) * 1989-06-24 1992-02-18 Berger Hermann J Method for impregnating tissue samples in paraffin
US5230865A (en) 1989-09-08 1993-07-27 Cem Corporation Ventable rupture diaphragm-protected container for heating contained materials by microwave radiation
US5049510A (en) 1990-01-05 1991-09-17 Fisher Scientific Company Process for histological tissue specimen treatment that includes variable sensitivity level control
US5030929A (en) 1990-01-09 1991-07-09 General Atomics Compact waveguide converter apparatus
US5086288A (en) * 1990-05-18 1992-02-04 Borroughs Tool & Equipment Corporation VATS interrogator accessory
US5068086A (en) 1990-06-12 1991-11-26 Raytheon Company Method and apparatus for batch fixating tissue specimens
DE4018955A1 (de) * 1990-06-13 1991-12-19 Werner Lautenschlaeger Probenbehaelter zum aufschliessen bzw. analysieren von probenmaterial
US5244787A (en) 1991-01-31 1993-09-14 Biogenex Laboratories Antigen retrieval in formalin-fixed tissues using microwave energy
DE4143541C2 (de) * 1991-02-19 1999-03-04 Mls Gmbh Vorrichtung zum Extrahieren von Proben mittels eines Lösungsmittels bei erhöhter Temperatur
US5256571A (en) 1991-05-01 1993-10-26 Cytyc Corporation Cell preservative solution
WO1992019952A1 (en) 1991-05-07 1992-11-12 Wescor, Inc. Improved staining method for histology and cytology specimens
US5460797A (en) 1991-05-08 1995-10-24 Streck Laboratories, Inc. Method for fixing tissues and cells for analysis using oxazolidine compounds
US5849517A (en) 1991-05-08 1998-12-15 Streck Laboratories, Inc. Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
US5696887A (en) 1991-08-05 1997-12-09 Biotek Solutions, Incorporated Automated tissue assay using standardized chemicals and packages
US5289140A (en) 1991-08-16 1994-02-22 Dako Japan Co., Ltd. Consistent diagnostic test method using microwaves
DE4136416C2 (de) * 1991-11-05 1994-01-13 Gossler Kg Oscar Vorrichtung zur Mikrowellen-Bestrahlung von Materialien
JP2996794B2 (ja) 1991-11-29 2000-01-11 株式会社千代田製作所 一槽式包埋装置の運転方法
US5422277A (en) * 1992-03-27 1995-06-06 Ortho Diagnostic Systems Inc. Cell fixative composition and method of staining cells without destroying the cell surface
DE4223116A1 (de) * 1992-04-30 1993-11-04 Mikrowellen Labor Systeme Vorrichtung zur verdampfungsbehandlung von vorzugsweise fluessigen stoffen, insbesondere reagenzstoffen, oder zum aufbereiten oder analysieren von probenmaterial
JPH06182718A (ja) * 1992-05-21 1994-07-05 Nara Pref Gov 樹脂含浸竹材の製造方法、およびこの樹脂含浸竹材の製造方法によって製造された樹脂含浸竹材、ならびにこの樹脂含浸竹材を用いて製造した編み針
JP3108099B2 (ja) * 1992-08-12 2000-11-13 バイオジェネックス ラボラトリーズ アルデヒド固定組織における免疫化学的染色の増強
US5401625A (en) 1993-06-24 1995-03-28 E. K. Industries, Inc. Histological composition for light microscopy
US5830417A (en) 1993-09-24 1998-11-03 Duquesne University Of The Holy Ghost Method and apparatus for microwave assisted chemical reactions
US5725835A (en) * 1993-11-11 1998-03-10 Lautenschlaeger; Werner Device for initiating and/or promoting chemical or physical processes in a material
US5432056A (en) * 1993-11-15 1995-07-11 Ventana Medical Systems, Inc. Bisulfite-based tissue fixative
US5431952A (en) 1994-02-28 1995-07-11 Board Of Trustees Operating Michigan State University Method for preservation of biological tissue
US6451551B1 (en) * 1994-03-11 2002-09-17 Biogenex Laboratories Releasing embedding media from tissue specimens
ATE173173T1 (de) * 1994-03-22 1998-11-15 Werner Lautenschlaeger Vorrichtung zum aufbereiten und/oder extrahieren von proben mittels eines verdampfungsfähigen mittels bei erhöhter temperatur
CA2147593C (en) * 1994-04-22 2008-07-29 Hyman C. Birnboim Dual purpose tissue fixative
US5532462A (en) 1994-04-29 1996-07-02 Communications & Power Industries Method of and apparatus for heating a reaction vessel with microwave energy
US5712605A (en) 1994-05-05 1998-01-27 Hewlett-Packard Co. Microwave resonator
CA2153215A1 (en) 1994-07-06 1996-01-07 Lu Wang Treatment of paraffin embedded tissue for gene analysis
EP0749513B1 (de) * 1995-01-05 2000-05-17 LAUTENSCHLÄGER, Werner Vorrichtung zur wärmebehandlung von materialien in einer heizkammer
DE19503591A1 (de) * 1995-02-03 1996-08-08 Werner Lautenschlaeger Verfahren und Vorrichtung zur Extraktions-Behandlung einer Probe
US5625706A (en) 1995-05-31 1997-04-29 Neopath, Inc. Method and apparatus for continously monitoring and forecasting slide and specimen preparation for a biological specimen population
US5796080A (en) 1995-10-03 1998-08-18 Cem Corporation Microwave apparatus for controlling power levels in individual multiple cells
US6072086A (en) 1996-04-12 2000-06-06 Intergen Company Method and composition for controlling formaldehyde fixation by delayed quenching
DE69600484T2 (de) 1996-08-02 1999-04-01 Milestone S.R.L., Sorisole Verfahren zur Bearbeitung von organischen Proben
DE19639022B4 (de) * 1996-09-23 2013-03-21 Mwt Mikrowellen Labor Technik Ag Verfahren und Vorrichtung zum Herstellen hochreiner flüssiger Chemikalien
DE19639021A1 (de) 1996-09-23 1998-03-26 Mikrowellen Systeme Mws Gmbh Vorrichtung und Verfahren zum Behandeln einer chemischen Substanz durch Erhitzen unter Druck
US5679333A (en) * 1996-10-25 1997-10-21 Dunphy; Brian William Formaldehyde-free tissue preservative compositions
DE19652339A1 (de) 1996-12-17 1998-06-18 Microm Laborgeraete Gmbh Vorrichtung zur Behandlung von Objekten
DE19652784A1 (de) 1996-12-19 1998-06-25 Dade Behring Marburg Gmbh Vorrichtung (Küvette) zur Aufnahme und Speicherung von Flüssigkeiten und zur Durchführung optischer Messungen
AU3615297A (en) * 1997-07-15 1999-02-10 Bernard Pajak Method for fixing and embedding tissues for histological preparations
US6793890B2 (en) * 1997-08-20 2004-09-21 The University Of Miami Rapid tissue processor
KR20010023070A (ko) * 1997-08-20 2001-03-26 더 유니버시티 오브 마이애미 고품질의 연속적인 재료 처리, 조직 고정-탈수-지방제거-함침 방법
US6017725A (en) * 1997-08-21 2000-01-25 Aaper Alcohol And Chemical Company Cytological fixative and dehydrating agent for treating histological and cytological tissue
US6183995B1 (en) 1997-09-05 2001-02-06 Lifespan Biosciences, Inc. Methods of measuring gene expression using wax-embedded tissue specimens
US6033912A (en) * 1997-11-13 2000-03-07 Milestone S.R.L. Method of controlling a chemical process heated by microwave radiation
DK1080228T3 (da) 1998-05-18 2010-08-16 Igenex Inc In situ hybridiseringsfremgangsmåde til detektering af target-nukleinsyrer
WO2000000813A1 (en) * 1998-06-30 2000-01-06 Lamina, Inc. Cytological and histological fixative composition and methods of use
US6242723B1 (en) * 1998-07-30 2001-06-05 Milestone S.R.L. Apparatus for performing chemical and physical processes without sample transfer within a microwave radiation field
US6054695A (en) * 1998-07-30 2000-04-25 Milestone S.R.L. Apparatus for condensing gases within a microwave radiation field
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
DE19928820A1 (de) 1999-06-17 2000-12-21 Ulrich Groth Fixiermittel für Zellen und Gewebe von Lebewesen
EP1208378B9 (en) * 1999-07-08 2014-12-10 Lee H. Angros Antigen recovery and/or staining apparatus and method
US6916608B2 (en) * 1999-09-10 2005-07-12 Becton, Dickinson And Company Composition for providing long term stability to cells for diagnostic testing
US6291180B1 (en) 1999-09-29 2001-09-18 American Registry Of Pathology Ultrasound-mediated high-speed biological reaction and tissue processing
US6248535B1 (en) 1999-12-20 2001-06-19 University Of Southern California Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
US6337189B1 (en) * 2000-02-08 2002-01-08 Streck Laboratories, Inc. Fixative system, method and composition for biological testing
AU2001240034A1 (en) 2000-03-03 2001-09-17 Ted Pella, Inc. Apparatus for dampening standing wave pattern generation in microwave oven
DE10015794A1 (de) 2000-03-27 2001-10-11 Univ Schiller Jena Vorrichtung zur Durchführung chemischer Reaktionen und Prozesse in Hochfrequenzfeldern
EP1156309B1 (de) * 2000-05-18 2003-04-16 Precisa Instruments AG Automatische Probenpräparation
DE10037417A1 (de) * 2000-07-24 2002-02-07 Friedrich Schiller Uni Jena Bu Vorrichtung zur Durchführung multipler chemischer Reaktionen und Prozesse in Hochfrequenzfeldern
DE10104320A1 (de) * 2001-01-25 2002-08-01 Univ Schiller Jena Vorrichtung zur Erfüllung von Sicherheitsfunktionen in Räumen mit Hochfrequenzstrahlung
US6875583B2 (en) 2001-05-22 2005-04-05 Ted Pella, Inc. Rapid microwave-assisted fixation of fresh tissue
US7297311B2 (en) 2001-06-29 2007-11-20 Sysmex Corporation Automatic smear preparing apparatus and automatic sample analysis system having the same
US6458598B1 (en) * 2001-08-13 2002-10-01 Dako A/S Process for preparing and presenting a tissue sample for histological study
DE20120649U1 (de) * 2001-12-20 2002-04-18 MLS Mikrowellen-Labor-Systeme GmbH, 88299 Leutkirch Vorrichtung zum Verschließen eines topfförmigen Aufschlussbehälters
US20030127313A1 (en) * 2001-12-20 2003-07-10 Milestone S.R.L. Device for closing a pot-like digestion vessel
US20030194352A1 (en) * 2001-12-20 2003-10-16 Milestone S.R.L. Device for closing a plurality of digestion vessesls
US6797928B2 (en) * 2002-04-23 2004-09-28 Ted Pella, Inc. Method and apparatus for the rapid decalcification and fixation of mineralized tissues
US7138226B2 (en) 2002-05-10 2006-11-21 The University Of Miami Preservation of RNA and morphology in cells and tissues
CA2502580C (en) * 2002-10-31 2013-09-10 University Of Massachusetts Rapid cell block embedding method and apparatus
EP1455174B1 (en) 2003-03-05 2004-12-15 Milestone S.r.l. Fixative
EP1464388A1 (de) 2003-04-04 2004-10-06 Mikrowellen-Systeme MWS GmbH Mikrowellen-Behandlung von chemischen Substanzen in einem Behälter
KR200327028Y1 (ko) * 2003-06-17 2003-09-19 장시창 인체조직검사기구
CA2543043C (en) * 2003-10-24 2013-09-17 The University Of Miami Simplified tissue processing
ATE416368T1 (de) * 2004-06-07 2008-12-15 Milestone Srl Verfahren und vorrichtung zur mikrowellen- unterstützten automatischen gewebebehandlung
US7273720B1 (en) * 2004-12-02 2007-09-25 Collaborative Laboratory Services, Llc Rapid tissue processing method and apparatus
US7273587B1 (en) * 2004-12-02 2007-09-25 Collaborative Laboratory Services, Llc Rapid tissue processing method and apparatus
AT503448B1 (de) * 2006-03-29 2007-10-15 Leica Mikrosysteme Gmbh Gerät zur präparation biologischer proben für die elektronenmikroskopie
AT504371B8 (de) * 2006-10-03 2008-09-15 Leica Mikrosysteme Gmbh Vorrichtung zur mikrowellen-gestützten präparation von proben

Also Published As

Publication number Publication date
EP1005633B1 (en) 2008-09-03
JP2008281573A (ja) 2008-11-20
DE69839963D1 (de) 2008-10-16
JP4164232B2 (ja) 2008-10-15
JP2001516869A (ja) 2001-10-02
TW571100B (en) 2004-01-11
CA2301924C (en) 2008-12-09
AU8900198A (en) 1999-03-08
US6586713B2 (en) 2003-07-01
ES2313752T3 (es) 2009-03-01
WO1999009390A1 (en) 1999-02-25
US8221996B2 (en) 2012-07-17
KR20010023070A (ko) 2001-03-26
EP1005633A1 (en) 2000-06-07
CA2301924A1 (en) 1999-02-25
JP4334601B2 (ja) 2009-09-30
EP2199774A1 (en) 2010-06-23
EP1005633A4 (en) 2003-01-22
AU746497B2 (en) 2002-05-02
EP2199774B1 (en) 2018-10-03
US6207408B1 (en) 2001-03-27
CA2635001C (en) 2012-12-04
DK1005633T3 (da) 2008-12-15
US7547538B2 (en) 2009-06-16
CA2635001A1 (en) 1999-02-25
US20080153127A1 (en) 2008-06-26
US20040004075A1 (en) 2004-01-08
US20010000487A1 (en) 2001-04-26

Similar Documents

Publication Publication Date Title
ATE407353T1 (de) Hochqualitatives durchlaufendes verfahren zur fixierung, dehydratisierung, entfettung und imprägnation von geweben
ES2031435T3 (es) Procedimiento y aparato para el tratamiento de materiales por ondas de radiofrecuencia usando una secuencia seleccionada de modos.
Mayers Histological fixation by microwave heating
US5089288A (en) Method for impregnating tissue samples in paraffin
CA2394194A1 (en) Rapid tissue processor
DE3485720D1 (de) Verfahren zum blanchieren von pilzen und anderen gemuesen.
ES2033957T3 (es) Procedimiento para lavar y/o enjuagar materiales textiles, asi como dispositivos apropiados para ello.
RU94036621A (ru) Способ подготовки биологических образцов к гистологическим исследованиям
ATE447984T1 (de) Verfahren zur behandlung von biologischem gewebe mittels mikrowellenbestrahlung
CN105363071A (zh) 生物材料的抗钙化处理方法
ES8101152A1 (es) Aparato para secar material textil.
DK306689A (da) Apparat til udbening af fjerkraekroppe
CN117405473A (zh) 一种动物肌肉组织的病理切片制作方法
CN111001040A (zh) 一种生物组织细胞外基质材料的制备方法
Chen et al. Scanning electron microscope studies on chicken gizzard structure as affected by cooking
RU2082407C1 (ru) Способ подготовки пантов оленей для получения ранторина и пантокрина
ATE57544T1 (de) Verfahren und vorrichtung zur nassbehandlung von textilen materialien.
BR0016228A (pt) Processo e aparelho para processamento de peles de animais
RU94045432A (ru) Способ лечения дефекта костей при хрящевых дисплазиях (варианты)
SU953494A1 (ru) Способ обработки биопсийного материала,содержащего жир
Wong Microwave stimulated diffusion method for processing oral mucosal tissue of hamster and human being
Bubenik et al. Velericorn antlers on a mature male moose (Alces a. gigas)
JP3852908B2 (ja) カンガルー皮を原料とする和楽器用胴皮の製造方法
JPS60153747A (ja) スライスハム様魚肉製品
RU2002101409A (ru) Способ замещения костных дефектов кисти

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties