ATA112186A - Verfahren zur herstellung neuer imidazo(4,5-b)chinolinderivate - Google Patents

Verfahren zur herstellung neuer imidazo(4,5-b)chinolinderivate

Info

Publication number
ATA112186A
ATA112186A AT0112186A AT112186A ATA112186A AT A112186 A ATA112186 A AT A112186A AT 0112186 A AT0112186 A AT 0112186A AT 112186 A AT112186 A AT 112186A AT A112186 A ATA112186 A AT A112186A
Authority
AT
Austria
Prior art keywords
producing new
new imidazo
chinoline derivatives
chinoline
derivatives
Prior art date
Application number
AT0112186A
Other languages
English (en)
Other versions
AT390257B (de
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Priority to AT0168989A priority Critical patent/AT390953B/de
Publication of ATA112186A publication Critical patent/ATA112186A/de
Application granted granted Critical
Publication of AT390257B publication Critical patent/AT390257B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT0112186A 1985-04-25 1986-04-25 Verfahren zur herstellung neuer imidazo(4,5-b)chinolin-derivate AT390257B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0168989A AT390953B (de) 1986-02-26 1989-07-12 Verfahren zur herstellung neuer imidazo(4,5-b) chinolin-2-thione

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72686985A 1985-04-25 1985-04-25
US06/832,212 US4668686A (en) 1985-04-25 1986-02-26 Imidazoquinoline antithrombrogenic cardiotonic agents

Publications (2)

Publication Number Publication Date
ATA112186A true ATA112186A (de) 1989-09-15
AT390257B AT390257B (de) 1990-04-10

Family

ID=27111398

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0112186A AT390257B (de) 1985-04-25 1986-04-25 Verfahren zur herstellung neuer imidazo(4,5-b)chinolin-derivate

Country Status (32)

Country Link
US (1) US4668686A (de)
KR (1) KR940000828B1 (de)
CN (1) CN1016175B (de)
AT (1) AT390257B (de)
AU (1) AU592983B2 (de)
BE (1) BE904671A (de)
CA (1) CA1298836C (de)
CH (1) CH675722A5 (de)
CY (1) CY1641A (de)
DE (1) DE3614132A1 (de)
DK (3) DK164868C (de)
EG (1) EG18104A (de)
ES (3) ES8708229A1 (de)
FI (1) FI83316C (de)
FR (1) FR2581065B1 (de)
GB (1) GB2174987B (de)
GR (1) GR861086B (de)
HK (1) HK64492A (de)
HU (1) HU195813B (de)
IL (1) IL78581A0 (de)
IT (1) IT1215651B (de)
LU (1) LU86406A1 (de)
MY (1) MY102086A (de)
NL (1) NL8601053A (de)
NO (1) NO163406C (de)
NZ (1) NZ215885A (de)
OA (1) OA08242A (de)
PT (1) PT82460B (de)
SE (1) SE461468B (de)
SG (1) SG29092G (de)
SU (3) SU1450746A3 (de)
YU (1) YU46054B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) * 1986-07-08 1987-10-20 Bristol-Myers Company 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
US4803210A (en) * 1987-05-29 1989-02-07 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic oxazolones
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) * 1990-11-10 1996-10-02 Daimler Benz Ag Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
MXPA06001674A (es) 2003-08-12 2006-05-12 3M Innovative Properties Co Compuestos que contienen imidazo hidroxilamina-sustituidos.
EP1658076B1 (de) 2003-08-27 2013-03-06 3M Innovative Properties Company Aryloxy- und arylalkylenoxy-substituierte imidazochinoline
EP1660026A4 (de) 2003-09-05 2008-07-16 3M Innovative Properties Co Behandlung von cd5+ b-zell-lyphom
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
AU2004278014B2 (en) 2003-10-03 2011-04-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
EP1685129A4 (de) 2003-11-14 2008-10-22 3M Innovative Properties Co Oximsubstituierte imidazoringverbindungen
CN1906192A (zh) * 2003-11-14 2007-01-31 3M创新有限公司 羟胺取代的咪唑环化合物
AR046781A1 (es) 2003-11-25 2005-12-21 3M Innovative Properties Co Derivados de imidazoquinolinas. composiciones farmaceuticas.
WO2005066170A1 (en) 2003-12-29 2005-07-21 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
CA2551399A1 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
WO2005094531A2 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
EP1831221B1 (de) 2004-12-30 2012-08-08 3M Innovative Properties Company Substituierte, chirale, fusionierte 1,2 imidazo-4,5-c-ringverbindungen
AU2005322898B2 (en) 2004-12-30 2011-11-24 3M Innovative Properties Company Chiral fused (1,2)imidazo(4,5-c) ring compounds
JP2008530022A (ja) 2005-02-04 2008-08-07 コーリー ファーマシューティカル グループ，インコーポレイテッド 免疫反応調節物質を含む水性ゲル処方物
AU2006213746A1 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods
JP2008535832A (ja) 2005-04-01 2008-09-04 コーリー ファーマシューティカル グループ，インコーポレイテッド ピラゾロピリジン−１，４−ジアミン、およびそのアナログ
US7943636B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
ES2558517T3 (es) 2006-08-02 2016-02-04 Cytokinetics, Inc. Ciertas entidades químicas, composiciones y métodos que comprenden imidazopirimidinas
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
US7851484B2 (en) 2007-03-30 2010-12-14 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
EA028060B1 (ru) 2011-07-13 2017-10-31 Сайтокинетикс, Инк. Комбинированная терапия бокового амиотрофического склероза

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

Also Published As

Publication number Publication date
KR860008177A (ko) 1986-11-12
ES557552A0 (es) 1988-07-16
SU1450746A3 (ru) 1989-01-07
EG18104A (en) 1992-09-30
SG29092G (en) 1992-05-15
DK164868B (da) 1992-08-31
HUT42089A (en) 1987-06-29
PT82460A (en) 1986-05-01
ES8801829A1 (es) 1988-02-16
NZ215885A (en) 1989-04-26
FI861684A0 (fi) 1986-04-22
AT390257B (de) 1990-04-10
DK164868C (da) 1993-01-11
FR2581065B1 (fr) 1990-02-02
GB2174987A (en) 1986-11-19
ES554336A0 (es) 1987-10-01
CH675722A5 (de) 1990-10-31
SE461468B (sv) 1990-02-19
BE904671A (fr) 1986-10-24
IT8620206A0 (it) 1986-04-24
ES8802521A1 (es) 1988-07-16
AU5641386A (en) 1986-10-30
ES8708229A1 (es) 1987-10-01
KR940000828B1 (ko) 1994-02-02
LU86406A1 (fr) 1986-11-05
OA08242A (en) 1987-10-30
DK165248C (da) 1993-03-22
DK81091A (da) 1991-05-01
GB2174987B (en) 1989-08-02
SU1470192A3 (ru) 1989-03-30
HK64492A (en) 1992-09-04
NO163406C (no) 1990-05-23
DK165248B (da) 1992-10-26
HU195813B (en) 1988-07-28
US4668686A (en) 1987-05-26
FI83316B (fi) 1991-03-15
DK80291A (da) 1991-04-30
SE8601907L (sv) 1986-10-26
GR861086B (en) 1986-09-01
GB8610037D0 (en) 1986-05-29
PT82460B (pt) 1988-11-30
AU592983B2 (en) 1990-02-01
DK165249C (da) 1993-03-22
CA1298836C (en) 1992-04-14
DK165249B (da) 1992-10-26
YU46054B (sh) 1992-12-21
CY1641A (en) 1992-11-06
FI861684A (fi) 1986-10-26
NO861617L (no) 1986-10-27
CN86102747A (zh) 1987-02-04
YU116787A (en) 1988-04-30
DK81091D0 (da) 1991-05-01
DK190986D0 (da) 1986-04-24
DK190986A (da) 1986-10-26
SE8601907D0 (sv) 1986-04-24
FR2581065A1 (fr) 1986-10-31
IL78581A0 (en) 1986-08-31
NO163406B (no) 1990-02-12
DK80291D0 (da) 1991-04-30
CN1016175B (zh) 1992-04-08
DE3614132A1 (de) 1986-11-27
NL8601053A (nl) 1986-11-17
ES557551A0 (es) 1988-02-16
IT1215651B (it) 1990-02-22
SU1560056A3 (ru) 1990-04-23
FI83316C (fi) 1991-06-25
MY102086A (en) 1992-03-31

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee
REN Ceased due to non-payment of the annual fee