ES554336A0 - Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas. - Google Patents

Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas.

Info

Publication number
ES554336A0
ES554336A0 ES554336A ES554336A ES554336A0 ES 554336 A0 ES554336 A0 ES 554336A0 ES 554336 A ES554336 A ES 554336A ES 554336 A ES554336 A ES 554336A ES 554336 A0 ES554336 A0 ES 554336A0
Authority
ES
Spain
Prior art keywords
onas
quinolin
imidazo
dihydro
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES554336A
Other languages
English (en)
Other versions
ES8708229A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES554336A0 publication Critical patent/ES554336A0/es
Publication of ES8708229A1 publication Critical patent/ES8708229A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES554336A 1985-04-25 1986-04-24 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas. Expired ES8708229A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72686985A 1985-04-25 1985-04-25
US06/832,212 US4668686A (en) 1985-04-25 1986-02-26 Imidazoquinoline antithrombrogenic cardiotonic agents

Publications (2)

Publication Number Publication Date
ES554336A0 true ES554336A0 (es) 1987-10-01
ES8708229A1 ES8708229A1 (es) 1987-10-01

Family

ID=27111398

Family Applications (3)

Application Number Title Priority Date Filing Date
ES554336A Expired ES8708229A1 (es) 1985-04-25 1986-04-24 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas.
ES557552A Expired ES8802521A1 (es) 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas
ES557551A Expired ES8801829A1 (es) 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES557552A Expired ES8802521A1 (es) 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas
ES557551A Expired ES8801829A1 (es) 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Country Status (32)

Country Link
US (1) US4668686A (es)
KR (1) KR940000828B1 (es)
CN (1) CN1016175B (es)
AT (1) AT390257B (es)
AU (1) AU592983B2 (es)
BE (1) BE904671A (es)
CA (1) CA1298836C (es)
CH (1) CH675722A5 (es)
CY (1) CY1641A (es)
DE (1) DE3614132A1 (es)
DK (3) DK164868C (es)
EG (1) EG18104A (es)
ES (3) ES8708229A1 (es)
FI (1) FI83316C (es)
FR (1) FR2581065B1 (es)
GB (1) GB2174987B (es)
GR (1) GR861086B (es)
HK (1) HK64492A (es)
HU (1) HU195813B (es)
IL (1) IL78581A0 (es)
IT (1) IT1215651B (es)
LU (1) LU86406A1 (es)
MY (1) MY102086A (es)
NL (1) NL8601053A (es)
NO (1) NO163406C (es)
NZ (1) NZ215885A (es)
OA (1) OA08242A (es)
PT (1) PT82460B (es)
SE (1) SE461468B (es)
SG (1) SG29092G (es)
SU (3) SU1450746A3 (es)
YU (1) YU46054B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) * 1986-07-08 1987-10-20 Bristol-Myers Company 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
US4803210A (en) * 1987-05-29 1989-02-07 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic oxazolones
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) * 1990-11-10 1996-10-02 Daimler Benz Ag Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
JP2007502293A (ja) 2003-08-12 2007-02-08 スリーエム イノベイティブ プロパティズ カンパニー ヒドロキシルアミン置換イミダゾ含有化合物
EP1658076B1 (en) 2003-08-27 2013-03-06 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted imidazoquinolines
CA2537763A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for cd5+ b cell lymphoma
AR046046A1 (es) 2003-10-03 2005-11-23 3M Innovative Properties Co Imidazoquinolinas alcoxi sustituidas. composiciones farmaceuticas.
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
CA2545825A1 (en) * 2003-11-14 2005-06-02 3M Innovative Properties Company Hydroxylamine substituted imidazo ring compounds
CA2545774A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Oxime substituted imidazo ring compounds
BRPI0416936A (pt) 2003-11-25 2007-01-16 3M Innovative Properties Co sistemas de anel de imidazo substituìdos e métodos
EP1701955A1 (en) 2003-12-29 2006-09-20 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
EP1699788A2 (en) 2003-12-30 2006-09-13 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl and imidazonaphthyridinyl sulfonamides
AU2005228150A1 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
JP5543068B2 (ja) 2004-12-30 2014-07-09 スリーエム イノベイティブ プロパティズ カンパニー キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物
US8034938B2 (en) 2004-12-30 2011-10-11 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
EP1846405A2 (en) 2005-02-11 2007-10-24 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo 4,5-c ring compounds and methods
CA2602590A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US7943610B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company Pyrazolopyridine-1,4-diamines and analogs thereof
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
PT2583970E (pt) 2006-08-02 2016-02-08 Cytokinetics Inc Certas entidades químicas, composições e métodos compreendendo imidazopirimidinas
EP2139478A4 (en) * 2007-03-30 2010-05-05 Cytokinetics Inc CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
EA201791043A1 (ru) 2011-07-13 2017-09-29 Сайтокинетикс, Инк. Комбинированная терапия бокового амиотрофического склероза

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

Also Published As

Publication number Publication date
SG29092G (en) 1992-05-15
AU5641386A (en) 1986-10-30
CY1641A (en) 1992-11-06
DK80291A (da) 1991-04-30
IL78581A0 (en) 1986-08-31
LU86406A1 (fr) 1986-11-05
EG18104A (en) 1992-09-30
DE3614132A1 (de) 1986-11-27
DK165248B (da) 1992-10-26
BE904671A (fr) 1986-10-24
FI83316B (fi) 1991-03-15
GR861086B (en) 1986-09-01
DK164868B (da) 1992-08-31
FI861684A (fi) 1986-10-26
SE8601907D0 (sv) 1986-04-24
OA08242A (en) 1987-10-30
HUT42089A (en) 1987-06-29
GB8610037D0 (en) 1986-05-29
HK64492A (en) 1992-09-04
DK165249C (da) 1993-03-22
MY102086A (en) 1992-03-31
CN1016175B (zh) 1992-04-08
NO163406B (no) 1990-02-12
GB2174987B (en) 1989-08-02
FR2581065B1 (fr) 1990-02-02
DK190986A (da) 1986-10-26
PT82460A (en) 1986-05-01
SU1560056A3 (ru) 1990-04-23
NO861617L (no) 1986-10-27
CN86102747A (zh) 1987-02-04
CA1298836C (en) 1992-04-14
GB2174987A (en) 1986-11-19
NZ215885A (en) 1989-04-26
ES557551A0 (es) 1988-02-16
NL8601053A (nl) 1986-11-17
PT82460B (pt) 1988-11-30
AT390257B (de) 1990-04-10
SE8601907L (sv) 1986-10-26
IT1215651B (it) 1990-02-22
FI83316C (fi) 1991-06-25
DK80291D0 (da) 1991-04-30
ES8801829A1 (es) 1988-02-16
SE461468B (sv) 1990-02-19
ES8802521A1 (es) 1988-07-16
CH675722A5 (es) 1990-10-31
DK165249B (da) 1992-10-26
DK164868C (da) 1993-01-11
DK190986D0 (da) 1986-04-24
ATA112186A (de) 1989-09-15
FI861684A0 (fi) 1986-04-22
YU46054B (sh) 1992-12-21
DK81091D0 (da) 1991-05-01
KR860008177A (ko) 1986-11-12
SU1450746A3 (ru) 1989-01-07
IT8620206A0 (it) 1986-04-24
ES8708229A1 (es) 1987-10-01
ES557552A0 (es) 1988-07-16
US4668686A (en) 1987-05-26
HU195813B (en) 1988-07-28
SU1470192A3 (ru) 1989-03-30
YU116787A (en) 1988-04-30
FR2581065A1 (fr) 1986-10-31
NO163406C (no) 1990-05-23
KR940000828B1 (ko) 1994-02-02
DK165248C (da) 1993-03-22
DK81091A (da) 1991-05-01
AU592983B2 (en) 1990-02-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401