FI861684A0 - Imidazokinoliner, antitrombogena hjaertmediciner. - Google Patents

Imidazokinoliner, antitrombogena hjaertmediciner.

Info

Publication number
FI861684A0
FI861684A0 FI861684A FI861684A FI861684A0 FI 861684 A0 FI861684 A0 FI 861684A0 FI 861684 A FI861684 A FI 861684A FI 861684 A FI861684 A FI 861684A FI 861684 A0 FI861684 A0 FI 861684A0
Authority
FI
Finland
Prior art keywords
imidazokinoliner
hjaertmediciner
antitrombogene
antitrombogene hjaertmediciner
Prior art date
Application number
FI861684A
Other languages
English (en)
Other versions
FI861684A (fi
FI83316C (fi
FI83316B (fi
Inventor
Nicholas A Meanwell
John J Wright
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI861684A0 publication Critical patent/FI861684A0/fi
Publication of FI861684A publication Critical patent/FI861684A/fi
Application granted granted Critical
Publication of FI83316B publication Critical patent/FI83316B/fi
Publication of FI83316C publication Critical patent/FI83316C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI861684A 1985-04-25 1986-04-22 Foerfarande foer framstaellning av farmaceutiskt aktiva 1,3-dihydro-2h-imidazo/4,5-b/kinolin-2-onderivat. FI83316C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72686985A 1985-04-25 1985-04-25
US72686985 1985-04-25
US06/832,212 US4668686A (en) 1985-04-25 1986-02-26 Imidazoquinoline antithrombrogenic cardiotonic agents
US83221286 1986-02-26

Publications (4)

Publication Number Publication Date
FI861684A0 true FI861684A0 (fi) 1986-04-22
FI861684A FI861684A (fi) 1986-10-26
FI83316B FI83316B (fi) 1991-03-15
FI83316C FI83316C (fi) 1991-06-25

Family

ID=27111398

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861684A FI83316C (fi) 1985-04-25 1986-04-22 Foerfarande foer framstaellning av farmaceutiskt aktiva 1,3-dihydro-2h-imidazo/4,5-b/kinolin-2-onderivat.

Country Status (32)

Country Link
US (1) US4668686A (fi)
KR (1) KR940000828B1 (fi)
CN (1) CN1016175B (fi)
AT (1) AT390257B (fi)
AU (1) AU592983B2 (fi)
BE (1) BE904671A (fi)
CA (1) CA1298836C (fi)
CH (1) CH675722A5 (fi)
CY (1) CY1641A (fi)
DE (1) DE3614132A1 (fi)
DK (3) DK164868C (fi)
EG (1) EG18104A (fi)
ES (3) ES8708229A1 (fi)
FI (1) FI83316C (fi)
FR (1) FR2581065B1 (fi)
GB (1) GB2174987B (fi)
GR (1) GR861086B (fi)
HK (1) HK64492A (fi)
HU (1) HU195813B (fi)
IL (1) IL78581A0 (fi)
IT (1) IT1215651B (fi)
LU (1) LU86406A1 (fi)
MY (1) MY102086A (fi)
NL (1) NL8601053A (fi)
NO (1) NO163406C (fi)
NZ (1) NZ215885A (fi)
OA (1) OA08242A (fi)
PT (1) PT82460B (fi)
SE (1) SE461468B (fi)
SG (1) SG29092G (fi)
SU (3) SU1450746A3 (fi)
YU (1) YU46054B (fi)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) * 1986-07-08 1987-10-20 Bristol-Myers Company 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
US4803210A (en) * 1987-05-29 1989-02-07 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic oxazolones
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) * 1990-11-10 1996-10-02 Daimler Benz Ag Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
AU2004266658A1 (en) 2003-08-12 2005-03-03 3M Innovative Properties Company Hydroxylamine substituted imidazo-containing compounds
KR101106812B1 (ko) 2003-08-27 2012-01-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 아릴옥시 및 아릴알킬렌옥시 치환된 이미다조퀴놀린
EP1660026A4 (en) 2003-09-05 2008-07-16 3M Innovative Properties Co TREATMENT FOR CD5 + B CELL LYMPHOMA
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
JP5043435B2 (ja) 2003-10-03 2012-10-10 スリーエム イノベイティブ プロパティズ カンパニー アルコキシ置換イミダゾキノリン
EP1685129A4 (en) 2003-11-14 2008-10-22 3M Innovative Properties Co OXIMSUBSTITUTED IMIDAZORING CONNECTIONS
JP2007511535A (ja) * 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー ヒドロキシルアミン置換イミダゾ環化合物
WO2005051317A2 (en) 2003-11-25 2005-06-09 3M Innovative Properties Company Substituted imidazo ring systems and methods
US8802853B2 (en) 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
JP2007517044A (ja) 2003-12-30 2007-06-28 スリーエム イノベイティブ プロパティズ カンパニー イミダゾキノリニル、イミダゾピリジニル、およびイミダゾナフチリジニルスルホンアミド
WO2005094531A2 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US7897609B2 (en) 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
US7943609B2 (en) 2004-12-30 2011-05-17 3M Innovative Proprerties Company Chiral fused [1,2]imidazo[4,5-C] ring compounds
WO2006083440A2 (en) 2004-12-30 2006-08-10 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
EP1846405A2 (en) 2005-02-11 2007-10-24 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo 4,5-c ring compounds and methods
CA2602590A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
JP2008535832A (ja) 2005-04-01 2008-09-04 コーリー ファーマシューティカル グループ，インコーポレイテッド ピラゾロピリジン−１，４−ジアミン、およびそのアナログ
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
ES2439590T3 (es) 2006-08-02 2014-01-23 Cytokinetics, Inc. Ciertas entidades químicas, composiciones y métodos
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
WO2008121333A1 (en) 2007-03-30 2008-10-09 Cytokinetics, Incorporated Certain chemical entities, compositions and methods
CA2849213A1 (en) 2011-07-13 2013-01-17 Cytokinetics, Inc. Combination of riluzole and ck-2017357 for treating als

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

Also Published As

Publication number Publication date
HUT42089A (en) 1987-06-29
GB2174987A (en) 1986-11-19
LU86406A1 (fr) 1986-11-05
NO163406B (no) 1990-02-12
DK165249B (da) 1992-10-26
DK80291A (da) 1991-04-30
ATA112186A (de) 1989-09-15
CN86102747A (zh) 1987-02-04
GB2174987B (en) 1989-08-02
YU46054B (sh) 1992-12-21
NL8601053A (nl) 1986-11-17
IL78581A0 (en) 1986-08-31
YU116787A (en) 1988-04-30
FR2581065A1 (fr) 1986-10-31
SU1450746A3 (ru) 1989-01-07
KR860008177A (ko) 1986-11-12
DK165248C (da) 1993-03-22
DK81091A (da) 1991-05-01
HK64492A (en) 1992-09-04
ES8802521A1 (es) 1988-07-16
IT8620206A0 (it) 1986-04-24
PT82460A (en) 1986-05-01
SU1560056A3 (ru) 1990-04-23
AT390257B (de) 1990-04-10
DK190986A (da) 1986-10-26
FI861684A (fi) 1986-10-26
FR2581065B1 (fr) 1990-02-02
BE904671A (fr) 1986-10-24
FI83316C (fi) 1991-06-25
DK80291D0 (da) 1991-04-30
SU1470192A3 (ru) 1989-03-30
OA08242A (en) 1987-10-30
DK165248B (da) 1992-10-26
NO163406C (no) 1990-05-23
ES557552A0 (es) 1988-07-16
IT1215651B (it) 1990-02-22
DK165249C (da) 1993-03-22
KR940000828B1 (ko) 1994-02-02
AU592983B2 (en) 1990-02-01
CN1016175B (zh) 1992-04-08
FI83316B (fi) 1991-03-15
SE8601907D0 (sv) 1986-04-24
NO861617L (no) 1986-10-27
ES8801829A1 (es) 1988-02-16
ES557551A0 (es) 1988-02-16
NZ215885A (en) 1989-04-26
EG18104A (en) 1992-09-30
ES8708229A1 (es) 1987-10-01
CY1641A (en) 1992-11-06
AU5641386A (en) 1986-10-30
ES554336A0 (es) 1987-10-01
CH675722A5 (fi) 1990-10-31
MY102086A (en) 1992-03-31
SG29092G (en) 1992-05-15
CA1298836C (en) 1992-04-14
HU195813B (en) 1988-07-28
DK81091D0 (da) 1991-05-01
DK164868C (da) 1993-01-11
DK190986D0 (da) 1986-04-24
PT82460B (pt) 1988-11-30
SE461468B (sv) 1990-02-19
SE8601907L (sv) 1986-10-26
DK164868B (da) 1992-08-31
GR861086B (en) 1986-09-01
US4668686A (en) 1987-05-26
DE3614132A1 (de) 1986-11-27
GB8610037D0 (en) 1986-05-29

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Legal Events

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MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS SQUIBB COMPANY