ES557552A0 - Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas - Google Patents

Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Info

Publication number
ES557552A0
ES557552A0 ES557552A ES557552A ES557552A0 ES 557552 A0 ES557552 A0 ES 557552A0 ES 557552 A ES557552 A ES 557552A ES 557552 A ES557552 A ES 557552A ES 557552 A0 ES557552 A0 ES 557552A0
Authority
ES
Spain
Prior art keywords
onas
quinolin
imidazo
dihydro
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES557552A
Other languages
English (en)
Other versions
ES8802521A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8802521A1 publication Critical patent/ES8802521A1/es
Publication of ES557552A0 publication Critical patent/ES557552A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES557552A 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas Expired ES8802521A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72686985A 1985-04-25 1985-04-25
US06/832,212 US4668686A (en) 1985-04-25 1986-02-26 Imidazoquinoline antithrombrogenic cardiotonic agents

Publications (2)

Publication Number Publication Date
ES8802521A1 ES8802521A1 (es) 1988-07-16
ES557552A0 true ES557552A0 (es) 1988-07-16

Family

ID=27111398

Family Applications (3)

Application Number Title Priority Date Filing Date
ES554336A Expired ES8708229A1 (es) 1985-04-25 1986-04-24 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas.
ES557551A Expired ES8801829A1 (es) 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas
ES557552A Expired ES8802521A1 (es) 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES554336A Expired ES8708229A1 (es) 1985-04-25 1986-04-24 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas.
ES557551A Expired ES8801829A1 (es) 1985-04-25 1987-05-14 Un procedimiento para la obtencion de 1,3-dihidro-2h-imidazo (4,5-b)-quinolin-2-onas

Country Status (32)

Country Link
US (1) US4668686A (es)
KR (1) KR940000828B1 (es)
CN (1) CN1016175B (es)
AT (1) AT390257B (es)
AU (1) AU592983B2 (es)
BE (1) BE904671A (es)
CA (1) CA1298836C (es)
CH (1) CH675722A5 (es)
CY (1) CY1641A (es)
DE (1) DE3614132A1 (es)
DK (3) DK164868C (es)
EG (1) EG18104A (es)
ES (3) ES8708229A1 (es)
FI (1) FI83316C (es)
FR (1) FR2581065B1 (es)
GB (1) GB2174987B (es)
GR (1) GR861086B (es)
HK (1) HK64492A (es)
HU (1) HU195813B (es)
IL (1) IL78581A0 (es)
IT (1) IT1215651B (es)
LU (1) LU86406A1 (es)
MY (1) MY102086A (es)
NL (1) NL8601053A (es)
NO (1) NO163406C (es)
NZ (1) NZ215885A (es)
OA (1) OA08242A (es)
PT (1) PT82460B (es)
SE (1) SE461468B (es)
SG (1) SG29092G (es)
SU (3) SU1450746A3 (es)
YU (1) YU46054B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) * 1986-07-08 1987-10-20 Bristol-Myers Company 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4803210A (en) * 1987-05-29 1989-02-07 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic oxazolones
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) * 1990-11-10 1996-10-02 Daimler Benz Ag Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
BRPI0412902A (pt) 2003-08-12 2006-09-26 3M Innovative Properties Co compostos contendo imidazo substituìdo por oxima
CA2536136C (en) 2003-08-27 2012-10-30 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted imidazoquinolines
AU2004270201A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for CD5+ B cell lymphoma
CA2540541C (en) 2003-10-03 2012-03-27 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
US8598192B2 (en) * 2003-11-14 2013-12-03 3M Innovative Properties Company Hydroxylamine substituted imidazoquinolines
WO2005048933A2 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Oxime substituted imidazo ring compounds
AU2004293078B2 (en) 2003-11-25 2012-01-19 3M Innovative Properties Company Substituted imidazo ring systems and methods
EP1701955A1 (en) 2003-12-29 2006-09-20 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
WO2005066169A2 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
CA2559863A1 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
US7915281B2 (en) 2004-06-18 2011-03-29 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US7943609B2 (en) 2004-12-30 2011-05-17 3M Innovative Proprerties Company Chiral fused [1,2]imidazo[4,5-C] ring compounds
ES2392648T3 (es) 2004-12-30 2012-12-12 3M Innovative Properties Company Compuestos quirales sustituidos que contienen un núcleo 1,2-imidazo-4,5-c condensado
US9248127B2 (en) 2005-02-04 2016-02-02 3M Innovative Properties Company Aqueous gel formulations containing immune response modifiers
EP1846405A2 (en) 2005-02-11 2007-10-24 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo 4,5-c ring compounds and methods
AU2006232377A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
CA2602590A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
WO2008008432A2 (en) 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
KR101410453B1 (ko) 2006-08-02 2014-06-27 싸이토키네틱스, 인코포레이티드 소정의 화학 물질, 조성물 및 방법
EP2139478A4 (en) * 2007-03-30 2010-05-05 Cytokinetics Inc CHEMICAL ENTITIES, COMPOSITIONS AND METHODS
EA028060B1 (ru) 2011-07-13 2017-10-31 Сайтокинетикс, Инк. Комбинированная терапия бокового амиотрофического склероза

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

Also Published As

Publication number Publication date
AU5641386A (en) 1986-10-30
AT390257B (de) 1990-04-10
KR940000828B1 (ko) 1994-02-02
ATA112186A (de) 1989-09-15
CY1641A (en) 1992-11-06
ES8802521A1 (es) 1988-07-16
CA1298836C (en) 1992-04-14
FI861684A (fi) 1986-10-26
FI83316B (fi) 1991-03-15
NL8601053A (nl) 1986-11-17
KR860008177A (ko) 1986-11-12
DK165248C (da) 1993-03-22
DK81091A (da) 1991-05-01
FI83316C (fi) 1991-06-25
CN1016175B (zh) 1992-04-08
DK81091D0 (da) 1991-05-01
SU1450746A3 (ru) 1989-01-07
FI861684A0 (fi) 1986-04-22
FR2581065A1 (fr) 1986-10-31
US4668686A (en) 1987-05-26
GR861086B (en) 1986-09-01
GB2174987B (en) 1989-08-02
DK165249B (da) 1992-10-26
NO861617L (no) 1986-10-27
SE8601907D0 (sv) 1986-04-24
EG18104A (en) 1992-09-30
SE461468B (sv) 1990-02-19
HU195813B (en) 1988-07-28
NO163406C (no) 1990-05-23
DK164868B (da) 1992-08-31
DK190986A (da) 1986-10-26
SU1470192A3 (ru) 1989-03-30
CH675722A5 (es) 1990-10-31
IT1215651B (it) 1990-02-22
AU592983B2 (en) 1990-02-01
DK164868C (da) 1993-01-11
PT82460B (pt) 1988-11-30
DK80291A (da) 1991-04-30
ES8801829A1 (es) 1988-02-16
IL78581A0 (en) 1986-08-31
DK80291D0 (da) 1991-04-30
HK64492A (en) 1992-09-04
ES8708229A1 (es) 1987-10-01
SU1560056A3 (ru) 1990-04-23
DK165248B (da) 1992-10-26
CN86102747A (zh) 1987-02-04
DK190986D0 (da) 1986-04-24
DK165249C (da) 1993-03-22
FR2581065B1 (fr) 1990-02-02
BE904671A (fr) 1986-10-24
SE8601907L (sv) 1986-10-26
OA08242A (en) 1987-10-30
ES557551A0 (es) 1988-02-16
IT8620206A0 (it) 1986-04-24
YU46054B (sh) 1992-12-21
SG29092G (en) 1992-05-15
NO163406B (no) 1990-02-12
MY102086A (en) 1992-03-31
GB8610037D0 (en) 1986-05-29
HUT42089A (en) 1987-06-29
NZ215885A (en) 1989-04-26
YU116787A (en) 1988-04-30
LU86406A1 (fr) 1986-11-05
PT82460A (en) 1986-05-01
GB2174987A (en) 1986-11-19
DE3614132A1 (de) 1986-11-27
ES554336A0 (es) 1987-10-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519