DK190986D0 - Imidazoquinolinonderivater - Google Patents

Imidazoquinolinonderivater

Info

Publication number
DK190986D0
DK190986D0 DK190986A DK190986A DK190986D0 DK 190986 D0 DK190986 D0 DK 190986D0 DK 190986 A DK190986 A DK 190986A DK 190986 A DK190986 A DK 190986A DK 190986 D0 DK190986 D0 DK 190986D0
Authority
DK
Denmark
Prior art keywords
imidazoquinoline derivatives
imidazoquinoline
derivatives
Prior art date
Application number
DK190986A
Other languages
English (en)
Other versions
DK190986A (da
DK164868C (da
DK164868B (da
Inventor
Nicholas A Meanwell
John J Wright
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK190986D0 publication Critical patent/DK190986D0/da
Publication of DK190986A publication Critical patent/DK190986A/da
Publication of DK164868B publication Critical patent/DK164868B/da
Application granted granted Critical
Publication of DK164868C publication Critical patent/DK164868C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK190986A 1985-04-25 1986-04-24 Imidazooe4,5-baaquinolin-2-on-derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse DK164868C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72686985A 1985-04-25 1985-04-25
US72686985 1985-04-25
US06/832,212 US4668686A (en) 1985-04-25 1986-02-26 Imidazoquinoline antithrombrogenic cardiotonic agents
US83221286 1986-02-26

Publications (4)

Publication Number Publication Date
DK190986D0 true DK190986D0 (da) 1986-04-24
DK190986A DK190986A (da) 1986-10-26
DK164868B DK164868B (da) 1992-08-31
DK164868C DK164868C (da) 1993-01-11

Family

ID=27111398

Family Applications (3)

Application Number Title Priority Date Filing Date
DK190986A DK164868C (da) 1985-04-25 1986-04-24 Imidazooe4,5-baaquinolin-2-on-derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse
DK080291A DK165248C (da) 1985-04-25 1991-04-30 1,3,9,9a-tetrahydro-imidazooe4,5-baaquinolin-2-oner samt fremgangsmaade til fremstilling deraf
DK081091A DK165249C (da) 1985-04-25 1991-05-01 Imidazooe4,5-baaquinolin-2-thionderivater samt fremgangsmaade til fremstilling deraf

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK080291A DK165248C (da) 1985-04-25 1991-04-30 1,3,9,9a-tetrahydro-imidazooe4,5-baaquinolin-2-oner samt fremgangsmaade til fremstilling deraf
DK081091A DK165249C (da) 1985-04-25 1991-05-01 Imidazooe4,5-baaquinolin-2-thionderivater samt fremgangsmaade til fremstilling deraf

Country Status (32)

Country Link
US (1) US4668686A (da)
KR (1) KR940000828B1 (da)
CN (1) CN1016175B (da)
AT (1) AT390257B (da)
AU (1) AU592983B2 (da)
BE (1) BE904671A (da)
CA (1) CA1298836C (da)
CH (1) CH675722A5 (da)
CY (1) CY1641A (da)
DE (1) DE3614132A1 (da)
DK (3) DK164868C (da)
EG (1) EG18104A (da)
ES (3) ES8708229A1 (da)
FI (1) FI83316C (da)
FR (1) FR2581065B1 (da)
GB (1) GB2174987B (da)
GR (1) GR861086B (da)
HK (1) HK64492A (da)
HU (1) HU195813B (da)
IL (1) IL78581A0 (da)
IT (1) IT1215651B (da)
LU (1) LU86406A1 (da)
MY (1) MY102086A (da)
NL (1) NL8601053A (da)
NO (1) NO163406C (da)
NZ (1) NZ215885A (da)
OA (1) OA08242A (da)
PT (1) PT82460B (da)
SE (1) SE461468B (da)
SG (1) SG29092G (da)
SU (3) SU1450746A3 (da)
YU (1) YU46054B (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775674A (en) * 1986-05-23 1988-10-04 Bristol-Myers Company Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) * 1986-07-08 1987-10-20 Bristol-Myers Company 7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
US4803210A (en) * 1987-05-29 1989-02-07 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic oxazolones
US4943573A (en) * 1989-11-01 1990-07-24 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) * 1990-11-10 1996-10-02 Daimler Benz Ag Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) * 1991-10-30 1998-06-18 Janssen Pharmaceutica Nv 1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5552267A (en) * 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5348960A (en) * 1992-04-03 1994-09-20 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5158958A (en) * 1992-04-03 1992-10-27 Bristol-Myers Squibb Company Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5208237A (en) * 1992-04-03 1993-05-04 Bristol-Meyers Squibb Company 7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
EP1653914A4 (en) 2003-08-12 2008-10-29 3M Innovative Properties Co COMPOUNDS CONTAINING OXIME SUBSTITUTED IMIDAZO STRUCTURE
MXPA06002199A (es) 2003-08-27 2006-05-22 3M Innovative Properties Co Imidazoquinolinas sustituidas con grupos ariloxi o arilalquilenoxi.
JP2007504269A (ja) 2003-09-05 2007-03-01 スリーエム イノベイティブ プロパティズ カンパニー Cd5+b細胞リンパ腫の治療方法
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
AU2004278014B2 (en) 2003-10-03 2011-04-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
CN1906192A (zh) * 2003-11-14 2007-01-31 3M创新有限公司 羟胺取代的咪唑环化合物
EP1685129A4 (en) 2003-11-14 2008-10-22 3M Innovative Properties Co OXIMSUBSTITUTED IMIDAZORING CONNECTIONS
MXPA06005910A (es) 2003-11-25 2006-08-23 3M Innovative Properties Co Sistemas de anillo imidazo sustituido y metodos.
US8802853B2 (en) 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
WO2005066169A2 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
US8697873B2 (en) 2004-03-24 2014-04-15 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US7915281B2 (en) 2004-06-18 2011-03-29 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method
WO2006038923A2 (en) 2004-06-18 2006-04-13 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006009826A1 (en) 2004-06-18 2006-01-26 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
CA2594674C (en) 2004-12-30 2016-05-17 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
JP5543068B2 (ja) 2004-12-30 2014-07-09 スリーエム イノベイティブ プロパティズ カンパニー キラル縮合[1,2]イミダゾ[4,5−c]環状化合物
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
WO2006086634A2 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
US7943636B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company 1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
AU2006232377A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines and analogs thereof
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
US8227603B2 (en) 2006-08-01 2012-07-24 Cytokinetics, Inc. Modulating skeletal muscle
US8299248B2 (en) 2006-08-02 2012-10-30 Cytokinetics, Incorporated Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
ES2558517T3 (es) 2006-08-02 2016-02-04 Cytokinetics, Inc. Ciertas entidades químicas, composiciones y métodos que comprenden imidazopirimidinas
US7851484B2 (en) 2007-03-30 2010-12-14 Cytokinetics, Inc. Certain chemical entities, compositions, and methods
SG10201605707UA (en) 2011-07-13 2016-09-29 Cytokinetics Inc Combination als therapy

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

Also Published As

Publication number Publication date
DK81091D0 (da) 1991-05-01
NZ215885A (en) 1989-04-26
DE3614132A1 (de) 1986-11-27
SU1450746A3 (ru) 1989-01-07
PT82460A (en) 1986-05-01
HUT42089A (en) 1987-06-29
FI861684A0 (fi) 1986-04-22
SE8601907D0 (sv) 1986-04-24
CH675722A5 (da) 1990-10-31
HK64492A (en) 1992-09-04
HU195813B (en) 1988-07-28
SU1560056A3 (ru) 1990-04-23
DK190986A (da) 1986-10-26
CY1641A (en) 1992-11-06
DK80291A (da) 1991-04-30
SE8601907L (sv) 1986-10-26
DK165249B (da) 1992-10-26
FI83316C (fi) 1991-06-25
NO163406B (no) 1990-02-12
OA08242A (en) 1987-10-30
DK165249C (da) 1993-03-22
CN86102747A (zh) 1987-02-04
BE904671A (fr) 1986-10-24
GB8610037D0 (en) 1986-05-29
YU46054B (sh) 1992-12-21
DK165248B (da) 1992-10-26
ES8802521A1 (es) 1988-07-16
NO163406C (no) 1990-05-23
FI83316B (fi) 1991-03-15
EG18104A (en) 1992-09-30
MY102086A (en) 1992-03-31
AU5641386A (en) 1986-10-30
AT390257B (de) 1990-04-10
ES557551A0 (es) 1988-02-16
ATA112186A (de) 1989-09-15
CN1016175B (zh) 1992-04-08
IL78581A0 (en) 1986-08-31
KR940000828B1 (ko) 1994-02-02
GR861086B (en) 1986-09-01
YU116787A (en) 1988-04-30
DK165248C (da) 1993-03-22
DK81091A (da) 1991-05-01
SU1470192A3 (ru) 1989-03-30
LU86406A1 (fr) 1986-11-05
DK80291D0 (da) 1991-04-30
ES8801829A1 (es) 1988-02-16
IT1215651B (it) 1990-02-22
FR2581065A1 (fr) 1986-10-31
FI861684A (fi) 1986-10-26
ES554336A0 (es) 1987-10-01
ES8708229A1 (es) 1987-10-01
PT82460B (pt) 1988-11-30
NL8601053A (nl) 1986-11-17
DK164868C (da) 1993-01-11
AU592983B2 (en) 1990-02-01
ES557552A0 (es) 1988-07-16
CA1298836C (en) 1992-04-14
KR860008177A (ko) 1986-11-12
IT8620206A0 (it) 1986-04-24
US4668686A (en) 1987-05-26
FR2581065B1 (fr) 1990-02-02
GB2174987A (en) 1986-11-19
GB2174987B (en) 1989-08-02
NO861617L (no) 1986-10-27
SG29092G (en) 1992-05-15
DK164868B (da) 1992-08-31
SE461468B (sv) 1990-02-19

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Legal Events

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PBP Patent lapsed